Clinical trials: Arterial Aneurysm
Aneurysm, Intracranial Aneurysm
Appraising the Embolization of Aneurysms Using Balt Optima™ Coil System (APPLY Study)
In recent years, many developments have been made to the tools and techniques used to treat IAs via endovascular intervention. Specifically, to the detachable coils themselves.
- Conditions
- Aneurysm, Intracranial Aneurysm, Ruptured Aneurysm, Subarachnoid Hemorrhage, Aneurysmal
- Trial name
- APPLY (NCT04499508)
- Testing
- Optima Coil System
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Vascular Neurology of Southern California Inc.
Intracranial Aneurysm
Contour Neurovascular System - European Pre-Market Unruptured Aneurysm
Cerus Endovascular is sponsoring a prospective, multi-center trial to document the safety and performance of the Contour Neurovascular System™ ("Contour").
- Trial name
- CERUS (NCT03680742)
- Testing
- Contour Neurovascular System
- Where
- 6 sites in Austria, Denmark and 1 more
- Volunteers
- 34 people
- Sponsor
- Cerus Endovascular, Inc.
Aortic Aneurysm and Dissection, Coronary Artery Disease (CAD)
Effects of Myofascial Release on Cardiac Patients After Median Sternotomy
After deciding to join this study and signing the informed consent form, participants will undergo the following interventions: All participants will receive a preoperative assessment (Tp) before surgery.
- Conditions
- Aortic Aneurysm and Dissection, Coronary Artery Disease (CAD), Valve Heart Disease
- Trial name
- NCT07649330
- Testing
- myofascial release+Routine Physical Therapy, Routine Physical therapy
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Siou-Pin Huang
Cerebral Aneurysm Unruptured, Cerebral Aneurysm
Use of Classic LMA During Endovascular Therapy
Background: Earlier treatment and resolution for patients with cerebral aneurysms is now possible due to earlier diagnosis. This observational study aims to evaluate the intraoperative cardiovascular parameters in patients with…
- Conditions
- Cerebral Aneurysm Unruptured, Cerebral Aneurysm, Hemodynamic Instability, Airway Morbidity
- Trial name
- NCT03288519
- Volunteers
- 60 people
- Sponsor
- Universidad de Antioquia
Aneurysm Cerebral
Dexmedetomidine Improves Recovery After Cranial Aneurysm Surgery
Dexmedetomidine induces analgesic and sedative effects and is reported to decrease agitation during emergence after general anesthesia in various surgeries.
- Trial name
- DACA (NCT03355534)
- Testing
- Intravenous dexmedetomidine, nasal dexmedetomidine, intravenous saline
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Zhihong LU
Cerebral Aneurysm
New Findings About Somatosensory Evoked Potentials (SEP) During Surgery for Cerebral Aneurysms
During surgery, electrophysiological signals will be acquired with the instrument (ISIS IOM, NeuroExplore, Software Version 4.4, Inomed) already in use at the Neurosurgery Service of the Neurocentro of the Hospital Civic Italian…
- Trial name
- NCT03152201
- Testing
- electrophysiological signal
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Luca Valci
Intracranial Aneurysm, Stent Complication
Stent-Assisted Coiling Followed by Ticagrelor Monotherapy Instead of Dual Antiplatelet Therapy in Unruptured Intracranial Aneurysm
The primary goal of the trial is to investigate whether the experimental arms (receiving the P2Y12 inhibitor Ticagrelor) compared with the control arm (taking dual antiplatelet therapy) could reduce bleeding complications in…
- Trial name
- SAC-TIDE (NCT06015477)
- Testing
- Ticagrelor monotherapy, Dual Antiplatelet Therapy
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Cerebral Aneurysms
Registry for Study of Coils in Intracranial Aneurysms
The current proposal describes a post-market, clinical registry of HydroSoft, aimed at gaining robust clinical data in a large set of patients to better define the advantages, and potentially, the disadvantages of the HydroSoft…
- Trial name
- Gel-the-nec (NCT01000675)
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Mayo Clinic
Abdominal Aortic Aneurysm, Abdominal Aortic Stenosis
Effectiveness of TAP (Transversus Abdominis Plane) Block for Abdominal Aortic Surgery
The goal of this study is to learn about the effectiveness of TAP block for pain relief after vascular surgery on the abdominal aorta.
- Conditions
- Abdominal Aortic Aneurysm, Abdominal Aortic Stenosis, Syndrome, Leriche
- Trial name
- NCT05860452
- Testing
- ropivacaine, normal saline
- Where
- Slovenia
- Volunteers
- 30 people
- Sponsor
- University Medical Centre Ljubljana
Intracranial Aneurysm, Aneurysm, Intracranial
Transcranial Doppler Ultrasound Monitoring During Flow-Diverter Embolization
Flow diverters have been approved since 2012 for the treatment of large, wide neck intracranial aneurysms. These devices have been associated with embolic events which cause blockage in a blood vessel and can result in long term…
- Conditions
- Intracranial Aneurysm, Aneurysm, Intracranial, Giant Intracranial Aneurysm
- Trial name
- NCT02354300
- Testing
- TCD Ultrasound
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Florida
Abdominal Aortic Aneurysm, Peripheral Artery Disease
A Study of Remote Ischaemic Preconditioning in Patients With Atherosclerosis Undergoing Vascular Surgery
The purpose of this study is to evaluate the effect of preoperative remote ischaemic preconditioning (RIPC) on organ damage and the functional characteristics of arteries in patients undergoing vascular surgery.
- Conditions
- Abdominal Aortic Aneurysm, Peripheral Artery Disease, Carotid Artery Stenosis
- Trial name
- NCT02689414
- Testing
- Remote ischaemic preconditioning, Control to RIPC
- Where
- Estonia
- Volunteers
- 98 people
- Sponsor
- Tartu University Hospital
MMPs and NGAL in Ruptured and Non-ruptured Aneurysms
Matrix Metalloproteinases (MMPs),Neutrophil Gelatinase-associated Lipocalin (NGAL) Tissue and Plasma Levels and Aneurysms
An association between arterial aneurysms and matrix metalloproteinases (MMPs) has been described previously. MMPs regulate extracellular structural proteins and tissue remodeling.
- Trial name
- NCT02145533
- Where
- Italy
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- University of Catanzaro
Intracranial Aneurysms
CARE: A Prospective Multicenter Case Study to Assess Radiation Exposure in Patients Treated With the Penumbra Coil 400
The primary objective of this study is to gather data on the radiation exposure in patients treated with the Penumbra Coil 400™ System (PC 400) or conventional coils per their respective indications for use.This is a multicenter…
- Trial name
- CARE (NCT02122133)
- Testing
- PC 400
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Penumbra Inc.
Stroke (CVA) or TIA, Headache, Migraine
Onabotulinum Toxin A (Botox) for the Treatment of Persistent Post-Stroke and Vascular Headache
Post stroke headache occurs in approximately 10-23% of all stroke patients. Its onset is shortly after experiencing a stroke, or stroke like event, and persists for at least three months.
- Conditions
- Stroke (CVA) or TIA, Headache, Migraine, Botulinum Toxins, Type A, Cerebral Venous Sinus Thrombosis
- Trial name
- NCT04580238
- Testing
- Botox 200 UNT Injection, Non Botox based Standard of Care Treatments for Headache/Migraine
- Where
- Canada
- Sponsor
- University of Alberta
Aortic Aneurysm, Thoracic, Descending Thoracic Aortic Dissection
Valiant Thoracic Stent Graft With the Captivia Delivery System in the Treatment of Descending Thoracic Aortic Diseases (VALIANT CAPTIVIA France)
The objective of this study is to assess the benefits of endovascular technique in terms of efficacy and safety of Valiant Thoracic Stent Graft with the Captivia Delivery System in the treatment of thoracic aortic disease, in a…
- Conditions
- Aortic Aneurysm, Thoracic, Descending Thoracic Aortic Dissection, Penetrating Ulcer, Aorta Thoracic; Traumatic Rupture
- Trial name
- NCT01775046
- Testing
- DTA patients (Valiant)
- Where
- 17 sites in France
- Volunteers
- 160 people
- Sponsor
- Medtronic Cardiovascular
Intracranial Aneurysms, Ruptured Aneurysm
Impact of Platelet Activation in Intracranial Aneurysm Rupture Risk - PLAQRAN
Sub arachnoid hemorrhage consecutive to intracranial aneurysm rupture is a devastating disease. Predictors of intracranial aneurysm rupture are limited and focus mainly on size and location.
- Trial name
- PLAQRAN (NCT03408379)
- Testing
- Collection of blood sample in aneurysm
- Where
- France
- Volunteers
- 230 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Hyperoxia, Hyperoxemia
Hyperoxemia and Oxygen Reserve Index During Neurointerventional Anesthesia
The goal of this observational study is to learn how often high blood oxygen levels (hyperoxemia) occur in adults receiving general anesthesia for planned (elective) neurointerventional procedures, such as brain aneurysm coiling…
- Conditions
- Hyperoxia, Hyperoxemia, Cerebrovascular Disorders, Intracranial Aneurysms
- Trial name
- NCT07859982
- Testing
- Oxygen Reserve Index Monitoring (Observational)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Intracranial Aneurysm
Pipeline Flex With SHield Technology Embolization - An International MulticEnter ObservationaL Post Market StuDy
This is a prospective, single-arm, multi-center post-market observational study assessing the performance of the Pipeline™ Flex Embolization Device with Shield Technology™ in subjects undergoing treatment for intracranial…
- Trial name
- SHIELD (NCT02719522)
- Testing
- Pipeline™ Flex Embolization Device with Shield Technology™
- Where
- 21 sites in Australia, Denmark and 9 more
- Volunteers
- 205 people
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Aneurysms, Flow Diverter
Flow-diverting Devices for the Treatment of Middle Cerebral Artery Bifurcation Aneurysms
The goal of this clinical trial is to learn if flow diverter (FD) offers advantages over conventional stent-assisted coiling in the treatment of middle cerebral artery (MCA) bifurcation aneurysms .
- Conditions
- Aneurysms, Flow Diverter, Middle Cerebral Artery Aneurysm, Coiling Therapy
- Trial name
- NCT07372612
- Testing
- Flow diverter, Stent-assisted coiling
- Volunteers
- 140 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Coronary Artery Disease, Ascending Aortic Aneurysm
Coronary Artery Bypass Grafting With Ascending Aortic Replacement
This retrospective study investigates early outcomes after CABG as well as graft patency rate in patients with concomitant AAR. 35 patients undergoing CABG with concomitant AAR (CABG+AAR group) were case-control matched to 35…
- Trial name
- NCT07071857
- Testing
- ECG CT angiography, TTFM, computed tomography of the aorta and/or grafts
- Volunteers
- 70 people
- Sponsor
- Tomsk Cardiology Research Institute