Clinical trials: Arterial Aneurysm
Intracranial Aneurysm
Risk Factors for Intracranial Aneurysm Recanalization After Endovascular Treatment.
Endovascular treatment is now the first line treatment for the management of intracranial aneurysms. However aneurysm recanalization is an important limitation to this treatment.
- Trial name
- ARETA (NCT01942512)
- Testing
- Endovascular treatment of intracranial aneurysm
- Where
- 22 sites in France
- Volunteers
- 1,275 people
- Sponsor
- CHU de Reims
Ruptured Aneurysm of Intracranial Artery, Stent-Assisted Coiling
Safety and Efficacy Analysis of Stent-assisted Coil Embolization in the Treatment of Acute Ruptured Intracranial Aneurysms in the Perioperative Period.
To determine the perioperative safety and efficacy of stent-assisted coil embolization of intracranial aneurysms in the acute phase.
- Conditions
- Ruptured Aneurysm of Intracranial Artery, Stent-Assisted Coiling, Efficacy and Safety
- Trial name
- NCT07683377
- Testing
- Perform stent-assisted aneurysm embolization on patients who meet the enrollment criteria, and administer antiplatelet drugs postoperatively according to the established trial protocol.
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Tang-Du Hospital
Blood Pressure
Arterial Properties of Thoracic Aorta Disease
A dissecting or intramural haematoma of the thoracic aorta (AH) is a haemorrhage that dissects the aortic wall. An entry point is detected at an intimal tear, ulcer or plaque rupture via imaging in almost 50% of cases.
- Trial name
- ao_diss (NCT01068691)
- Testing
- Ambulatory blood pressure monitoring (to evaluate the level of blood pressure)
- Where
- France
- Volunteers
- 180 people
- Sponsor
- University Hospital, Grenoble
Aneurysm, Brain Aneurysm
Multimodal Biocollection Linked to the French Register of Intracranial Aneurysms
The purpose of the bCAN study is to create a prospective collection of multimodal data and human samples, linked to the French Intracranial Aneurysm Registry (FRAN).
- Conditions
- Aneurysm, Brain Aneurysm, Congenital Disease
- Trial name
- bCAN (NCT06689410)
- Testing
- blood or saliva sample
- Where
- 26 sites in France
- Volunteers
- 1,100 people
- Sponsor
- Nantes University Hospital
Aortic Aneurysm, Iliac Aneurysm
Safety and Efficacy of the Gore® Excluder® Iliac Branch Platform and Analysis of Its Behavior in Combination With the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis (IBERVIX)
Aorto-iliac aneurysms with involvement of the iliac bifurcation or hypogastric artery aneurysms constitute only 20% of all aneurysmal pathology of the abdominal aorta.
- Trial name
- IBERVIX (NCT04356313)
- Testing
- GORE® EXCLUDER® Iliac Branch Endoprosthesis
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Asociacion para el Estudio de la Enfermedades Vasculares de Galicia
Cerebral Aneurysm
NIRS and BIS Monitoring During Cerebral Aneurysm Coiling
This prospective observational study aims to evaluate the effectiveness of Near-Infrared Spectroscopy (NIRS) and Bispectral Index (BIS) monitoring during endovascular coil embolization of cerebral aneurysms under general…
- Trial name
- NIRSBIS-ANEUR (NCT07438275)
- Testing
- Near-Infrared Spectroscopy (NIRS) and Bispectral Index (BIS) Monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Dokuz Eylul University
Dissecting Aneurysm of Cerebral Artery, Intramural Hematomas
Atorvastatin in the TREATment of Intracranial Unruptured VertebroBasilar Dissecting Aneurysms
This study was designed to whether there is a measurable reduction in inflammation in walls of unruptured vertebrobasilar dissecting aneurysms with atorvastatin.
- Conditions
- Dissecting Aneurysm of Cerebral Artery, Intramural Hematomas, Inflammation Vascular
- Trial name
- ATREAT-VBD (NCT04943783)
- Testing
- Atorvastatin 20mg
- Where
- 2 sites in China
- Volunteers
- 40 people
- Sponsor
- Beijing Neurosurgical Institute
PAD - Peripheral Arterial Disease, PAD
Tack Optimized Balloon Angioplasty Post-Market Study
The objective of this study is to obtain outcomes following dissection repair with the Tack Endovascular System in a broad population of patients undergoing endovascular treatment of lesions within the superficial femoral…
- Conditions
- PAD - Peripheral Arterial Disease, PAD, Dissection, Arterial Dissection
- Trial name
- TOBA PMS (NCT05361967)
- Testing
- The Tack Endovascular System
- Where
- 10 sites in United States
- Volunteers
- 6 people
- Sponsor
- Spectranetics Corporation
Cerebral Aneurysm
Effect of Sirolimus on Molecular Alterations in Cerebral Aneurysms
The objective of this study is to explore the effects of Sirolimus on the underlying molecular alterations of cerebral aneurysms.
- Trial name
- NCT04141020
- Testing
- Microsurgical clipping, Endovascular treatment, Sirolimus
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Miami
Intracranial Aneurysm
Reduction of Microembolism After the Intervention Surgery of Intracranial Aneurysms by Administration of Tirofiban
The goal of this clinical trial is to investigate whether intravenous injection of tilofiban can reduce microembolism in patients with unruptured intracranial aneurysms after Stent-Assisted Coil Embolization.The main questions it…
- Trial name
- NCT05841147
- Testing
- Tirofiban, normal saline
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Lu Hua
Acute Coronary Syndrome, Angiographic Evidence if Coronary Aneurysms
The Italian Coronary Artery Aneurysm and Ectasia In Patients With Acute Coronary Syndrome
The ITACA study is a prospective, observational no profit registry enrolling patients with Acute Coronary Syndrome and angiographic evidence of coronary aneurysms and/or ectasia.
- Conditions
- Acute Coronary Syndrome, Angiographic Evidence if Coronary Aneurysms, Ectasia
- Trial name
- ITACA (NCT05051917)
- Where
- 2 sites in Italy
- Volunteers
- 500 people
- Sponsor
- Federico II University
Intracranial Aneurysm, Natural History
The Prospective Cohort Study on the Benefit-risk of Antithrombotic or Anticoagulant Therapy in Patients With Unruptured Intracranial Aneurysms Associated With Ischemic Heart Disease or Ischemic Cerebrovascular Disease
This is a registry study of the natural course of unruptured intracranial aneurysms (UIA). In addition, the investigators will analyze the benefit-risk of antithrombotic or anticoagulant therapy in patients with unruptured…
- Conditions
- Intracranial Aneurysm, Natural History, Ischemic Heart Disease, Ischemic Cerebrovascular Disease
- Trial name
- NCT03153878
- Volunteers
- 1,800 people
- Sponsor
- Liu Zhiyong
Brain Neoplasm, Intracranial Aneurysm
Subclavian Vein catheterization_Seldinger Vs Modified Seldinger
Seldinger technique is a minimally invasive technique in which the practitioner accesses the target vessel with a small bore needle, then dilates to the size required for the catheter.
- Conditions
- Brain Neoplasm, Intracranial Aneurysm, Cerebrovascular Moyamoya Disease
- Trial name
- MS (NCT02090010)
- Testing
- Seldinger technique, Modified Seldinger technique
- Where
- South Korea
- Volunteers
- 418 people
- Sponsor
- Seoul National University Hospital
Cerebral Aneurysm, Arteriovenous Malformations
Exploration of Anticoagulation Program in Cerebral Aneurysm and Arteriovenous Malformations With Hybrid Operation 1
In the stage of registration study, our purpose is to find out the safety range of activated coagulation time level in cerebral aneurysm and arteriovenous malformations with hybrid operation.
- Trial name
- EAPCAAMHO1 (NCT03306823)
- Where
- China
- Volunteers
- 556 people
- Sponsor
- Beijing Tiantan Hospital
Intracranial Aneurysm
Real-World Study of Woven EndoBridge for Intracranial Aneurysm Treatment
We designed the Real-World Study of Woven EndoBridge for Intracranial Aneurysm Treatment (WEB-RWS), an ambidirectional, multicenter, post-market real-world study with a prospective active surveillance component.
- Trial name
- WEB-RWS (NCT07620626)
- Testing
- Intrasaccular Flow Disruption Device
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Xuanwu Hospital, Beijing
Brain Aneurysm
Post Market Registry Study of Intracranial Aneurysms Treated With Sugita Clipping Devices
The objective of this study is to verify the performance and safety of the Sugita Aneurysm Clips devices when used as intended and to identify possible risk factors.
- Trial name
- T2_PMCF (NCT06798740)
- Testing
- Sugita Titanium Aneurysm Clip II
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Mizuho Corporation
Coronary Artery Disease
Vascular Function on the First Day After Cardiac Surgery
This study examines the flow mediated dilation (FMD) of the brachial artery before and after cardiac surgery. FMD is measured with ultrasound technique.
- Trial name
- NCT02001090
- Where
- Norway
- Volunteers
- 25 people
- Sponsor
- Norwegian University of Science and Technology
Cerebral Aneurysms, Intracranial Aneurysms
NOn-inVAsive Blood Pressure Monitoring in Intracranial Aneurysm Embolization
The goal of this clinical trial is to evaluate whether non-invasive continuous blood pressure monitoring (NVBP) using the ClearSight system can safely serve as an alternative to radial arterial catheterization for invasive…
- Conditions
- Cerebral Aneurysms, Intracranial Aneurysms, Coil Embolization, Hemodynamic Instability
- Trial name
- NOVA (NCT07246148)
- Testing
- Non-invasive continuous blood pressure monitoring, Invasive arterial blood pressure monitoring
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Korea University Anam Hospital
Vascular; Lesion, Central Nervous System, Brain Tumor
Intraoperative Fluorescence With Augmented Reality
This is a study looking at a new way to evaluate vascular problems or tumors in brain surgery patients using a standard \& approved intravenous dye and augmented reality.
- Conditions
- Vascular; Lesion, Central Nervous System, Brain Tumor, Cerebral Aneurysm, Cerebral AVM
- Trial name
- NCT03888014
- Testing
- GLOW800, indocyanine green (ICG)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Cedars-Sinai Medical Center
Cerebral Aneurysm, Thromboembolic Disease
Prospective, Single-Arm, Multicenter Study to Evaluate the Effectiveness and Safety of Endovascular Treatment in Patients With Cerebral Aneurysms Using P64 and P48 Flow-Diverter Stents
The use of flow-diverting stents for the endovascular treatment of cerebral aneurysms has proven to be effective and efficient in several clinical studies, leading to its widespread adoption.
- Trial name
- pSPAIN_HPC (NCT06201598)
- Testing
- Group 1 - Intervention 1
- Where
- 11 sites in Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Universitario Central de Asturias