Clinical trials: Arterial Embolization
Intracranial Aneurysm, Aneurysm, Intracranial
Transcranial Doppler Ultrasound Monitoring During Flow-Diverter Embolization
Flow diverters have been approved since 2012 for the treatment of large, wide neck intracranial aneurysms. These devices have been associated with embolic events which cause blockage in a blood vessel and can result in long term…
- Conditions
- Intracranial Aneurysm, Aneurysm, Intracranial, Giant Intracranial Aneurysm
- Trial name
- NCT02354300
- Testing
- TCD Ultrasound
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Florida
Prostatic Hyperplasia, Benign, Prostatic Hypertrophy, Benign
Clinical Trial of Prostatic Arterial Embolization Versus a Sham Procedure to Treat Benign Prostatic Hyperplasia
The purpose of this study is to determine whether prostatic arterial embolization (PAE) compared is an effective and safe treatment for benign prostatic hyperplasia in patients with severe lower urinary tract symptoms not…
- Conditions
- Prostatic Hyperplasia, Benign, Prostatic Hypertrophy, Benign, Genital Diseases, Male, Lower Urinary Tract Symptoms
- Trial name
- NCT02074644
- Testing
- Prostatic Arterial Embolization
- Where
- Portugal
- Volunteers
- 80 people
- Sponsor
- João Martins Pisco
Intracranial Aneurysm
Bioabsorbable/Nufairy Coil Application Trial in China
The scope of this trial is the collection and analysis of effectiveness and safety endpoints, related to the use of the Bioabsorbable/Nufairy Coil Embolization System in the treatment of intracranial aneurysms.
- Trial name
- NuCATCH (NCT06466564)
- Testing
- Nufairy® Coil embolization system for intracranial aneurysm
- Where
- China
- Volunteers
- 258 people
- Sponsor
- MicroPort NeuroTech Co., Ltd.
Intracranial Aneurysm
Medina Embolization Device In Neurovascular Aneurysm Study
A global prospective, multi-center, single-arm, post-market clinical follow-up (PMCF) study conducted to assess the performance of the Medina Embolization Device when used in unruptured and ruptured intracranial aneurysms.
- Trial name
- MEDINA (NCT02982200)
- Where
- 3 sites in Austria, Italy and 1 more
- Volunteers
- 15 people
- Sponsor
- Medtronic Neurovascular Clinical Affairs
Obesity, Type2diabetes
Metabolic Effects of Bariatric Arterial Embolization vs Bariatric Surgery
Obesity and Type 2 diabetes mellitus (DMT2) are two of the most common chronic diseases of the Western society. Obesity is one critical factor in DMT2 development, with weight loss having profound beneficial effects on DMT2 and…
- Conditions
- Obesity, Type2diabetes, Bariatric Surgery Candidate, Metabolic Disease
- Trial name
- BEOD (NCT05859022)
- Testing
- Roux-en-Y gastric By-pass (RYGB) surgery, Bariatric Arterial Embolization (BAE) procedure
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Nova de Lisboa
Carcinoma, Hepatocellular
Transarterial Embolization Alone Versus Drug-Eluting Beads Chemoembolization for Hepatocellular Carcinoma
Developed in Japan in the 1980s, TACE became the most frequent treatment for unresectable hepatocellular carcinoma (HCC) in patients with preserved hepatic function after 2002, when two radiochemotherapies (RCTs) showed survival…
- Trial name
- RAD-18-TAcE (NCT04803019)
- Testing
- DEB-TACE, TAE
- Where
- Italy
- Volunteers
- 154 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Uterine Fibroid
Evaluation of Uterine Fibroids by CEUS and SHAPE Pre and Post UAE
This study goals are to determine the patterns of uterine fibroid vascularity pre and post UAE using CEUS resulting in an alternative to gadolinium-enhanced MRI that is less expensive, has less contra-indications and side…
- Trial name
- NCT06705075
- Testing
- Perfluten
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Thomas Jefferson University
Liver Cancer
HAIC Sequential TAE Combined With Lenvatinib and Tislelizumab in Unresectable HCC
Patients with unresectable hepatocellular carcinoma will receive hepatic arterial infusion chemotherapy (HAIC) sequential transarterial embolization combined with lenvatinib and tislelizumab.
- Trial name
- FRONT-1 (NCT05532319)
- Testing
- HAIC sequential TAE combined with lenvatinib and tislelizumab
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Guangxi Medical University
Ruptured Aneurysm of Intracranial Artery, Stent-Assisted Coiling
Safety and Efficacy Analysis of Stent-assisted Coil Embolization in the Treatment of Acute Ruptured Intracranial Aneurysms in the Perioperative Period.
To determine the perioperative safety and efficacy of stent-assisted coil embolization of intracranial aneurysms in the acute phase.
- Conditions
- Ruptured Aneurysm of Intracranial Artery, Stent-Assisted Coiling, Efficacy and Safety
- Trial name
- NCT07683377
- Testing
- Perform stent-assisted aneurysm embolization on patients who meet the enrollment criteria, and administer antiplatelet drugs postoperatively according to the established trial protocol.
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Tang-Du Hospital
Uveal Melanoma, Liver Metastases
Halt Growth of Liver Tumors From Uveal Melanoma With Closure of Liver Artery Following Injection of GM-CSF
Patients with uveal melanoma metastatic to the liver will be treated with embolization of the hepatic artery every 4 weeks. GM-CSF (granulocyte-macrophage colony simulating factor) or normal saline will be injected into one of…
- Trial name
- NCT00661622
- Testing
- GM-CSF, Embolization
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Knee Osteoarthritis
Genicular Artery Embolization vs Nerve Ablation Intervention (GENI) for Knee Osteoarthritis
The genicular artery embolization vs nerve ablation intervention (GENI) knee OA study is a three-arm randomized controlled trial to evaluate symptoms of knee osteoarthritis (OA) in patients after receiving one of three…
- Trial name
- NCT06166628
- Testing
- Geniculate artery embolization, Genicular nerve phenol nerve ablation, Skin infiltration of 2cc of 0.25% bupivacaine at the knee
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- David Clinkard
Migraine
Safety and Efficacy of Middle Meningeal Artery Embolization for the Treatment of Migraine.
This study is a multicenter, prospective, double-blind, multi-arm, randomized controlled trial that investigates whether middle meningeal artery embolization is superior to current standard pharmacotherapy for migraine.
- Trial name
- FAST-EM-2 (NCT07633067)
- Testing
- Middle meningeal artery embolization, Conventional standard pharmacotherapy for migraine
- Volunteers
- 150 people
- Sponsor
- The Affiliated Hospital Of Guizhou Medical University
Benign Prostatic Hyperplasia (BPH), Minimal Invasive Surgery
Minimally Invasive Prostate Interventions Registry (MIST Study)
This study is a multicenter prospective patient registry designed to evaluate clinical, functional, and safety outcomes after minimally invasive prostate interventions (MIST) performed for benign prostatic obstruction (BPO)…
- Conditions
- Benign Prostatic Hyperplasia (BPH), Minimal Invasive Surgery, LUTS
- Trial name
- MIST (NCT07242807)
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 2,000 people
- Sponsor
- Necmettin Erbakan University
Migraine
Middle Meningeal Artery Embolization for Chronic Migraine
The main goal of this study is to find out how well middle meningeal artery coil embolization works for patients with recurrent chronic migraines that are not resolved with medication.
- Trial name
- NCT07044648
- Testing
- Middle Meningeal Artery Embolization
- Sponsor
- Wake Forest University Health Sciences
Benign Prostatic Hyperplasia, Post-Op Complication
Artery Embolization vs Operation of Benign Prostate Hyperplasia
Aim of the study is to compare prostate artery embolization (PAE) to the established surgical treatment for patient acceptance, morbidity, complications, and the functional outcomes.
- Conditions
- Benign Prostatic Hyperplasia, Post-Op Complication, Embolization Therapeutic, Transurethral Resection of Prostate Syndrome
- Trial name
- NORTAPE (NCT04084938)
- Testing
- Prostate operation or prostate artery embolization
- Where
- Norway
- Volunteers
- 140 people
- Sponsor
- Oslo University Hospital
Chronic Subdural Hematoma, Subdural Hematoma
Dartmouth Middle Meningeal Embolization Trial (DaMMET)
Chronic subdural hematomas (cSDH) are one form of bleeding in the head. They are one of the most common diseases encountered by neurosurgeons across the country.
- Trial name
- DAMMET (NCT04270955)
- Testing
- Embolization of the Middle Meningeal Artery, Standard of care including possible surgical evacuation of subdural hematoma
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Hepatocellular Carcinoma
Microparticle Enhanced Cytotoxic Transarterial Embolization Therapy in Hepatocellular Carcinoma
This is a non-randomized, prospective, pilot, Multicenter Study of Drug-eluting bead transarterial chemoembolization (DEB-TACE) using Doxorubicin-Loaded Embozene® Tandem™ Microspheres to treat hepatocellular carcinoma (HCC).
- Trial name
- MIRACLE I (NCT01798134)
- Testing
- TANDEM™
- Where
- 7 sites in Germany
- Volunteers
- 25 people
- Sponsor
- Boston Scientific Corporation
Hemorrhoid, Hemorrhoid Bleeding
Bleeding Reduction in Grade II-III Haemorrhoids Through Embolization Treatment
BRIGHT is a Europe-wide study that will follow up to 250 adults with bleeding symptoms from haemmorhoids (Grade II-III categories).
- Trial name
- BRIGHT (NCT07264413)
- Testing
- Haemorrhoid artery embolizsation (HAE)
- Volunteers
- 250 people
- Sponsor
- Cardiovascular and Interventional Radiological Society of Europe
Hemorrhage, Gastrointestinal Hemorrhage
HISTOACRYL® Used for Embolization of Thoracoabdominal Artery Bleeding
This observational study will collect information from adult patients in Japan who are treated with Histoacryl® to stop bleeding from arteries in the chest or abdomen, in order to better understand how well the treatment works…
- Conditions
- Hemorrhage, Gastrointestinal Hemorrhage, Hemoptysis, Postpartum Hemorrhage
- Trial name
- HEAL (NCT07753005)
- Testing
- Embolization therapy
- Where
- 11 sites in Japan
- Volunteers
- 176 people
- Sponsor
- Aesculap AG
Hypervascular Tumor and Arteriovenous Malformation
A Multicenter, Open-label Study for E7040 in Japanese Subjects With Hypervascular Tumor and Subjects With Arteriovenous Malformation
To evaluate the efficacy and safety of transcatheter arterial embolization with E7040 in Japanese subjects with hypervascular tumor or arteriovenous malformation
- Trial name
- NCT01677624
- Testing
- E7040
- Where
- 10 sites in Japan
- Volunteers
- 28 people
- Sponsor
- Eisai Co., Ltd.