Clinical trials: Arterial Hypotension
Intraoperative Hypotension
Hypotension Prediction Index (HPI) in Lung Resections
Perioperative hypotension is a risk factor for perioperative complications. Advances in machine learning and artificial intelligence have produced an algorithm that predicts the occurrence of hypotension episodes by analyzing an…
- Trial name
- NCT06202638
- Testing
- HemoSphere monitor with Acumen Hypotension Prediction Index Software
- Where
- 3 sites in Greece, Poland
- Volunteers
- 77 people
- Sponsor
- John Paul II Hospital, Krakow
Hypotension,Controlled
Correlation Analysis of the Effects of Management Pressure Goals and Control Volume Goals in Patients in Spinal Surgery
The investigators study 160 patients undergoing spinal surgery.Participants will be randomly divided into study group and control group.The study group will receive controlled hypotension by nitroglycerin and be divided into 3…
- Trial name
- NCT03917004
- Testing
- Nitroglycerin
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Liang Bing
Hypotension, End Stage Renal Disease
Pharmacokinetic and Pharmacodynamic Effects of MTR107 in End-Stage Renal Disease (ESRD) Patients
MTR107 effect on blood pressure throught the dialysis procedure and its ability to prevent Intra dialytic Hypotension
- Conditions
- Hypotension, End Stage Renal Disease, Intra Dialytic Hypotension
- Trial name
- NCT00448071
- Testing
- MTR107
- Where
- 2 sites in Israel
- Volunteers
- 12 people
- Sponsor
- Wolfson Medical Center
Hypotension, Cesarean Section Complications
Norepinephrine to Prevent Hypotension in Ceasrean Delivery
This study will be conducted on 40 healthy women having spinal anesthesia for elective cesarean delivery in the operating rooms at Menoufia university hospital.
- Trial name
- NCT05248932
- Testing
- Norepinephrine bolus, cardiometry, Norepinephrine infusion
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Desaturation, Bradycardia
NTX Wireless Patient Monitoring System
Determine the accuracy of the NTX wireless monitoring system alerts Evaluate patient compliance with wearing device Determine false alarm rates
- Conditions
- Desaturation, Bradycardia, Tachycardia, Hypertension
- Trial name
- NCT00654693
- Testing
- Rapid Response Team
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Vanderbilt University
Anesthesia
Preventing Hypotension in the Spine During Cesarean Delivery.
Examining the advantages associated with the utilization of noradrenaline in preventing spinal hypotension during cesarean births.
- Trial name
- NCT06231316
- Testing
- Norepinephrine Injection
- Volunteers
- 100 people
- Sponsor
- Assiut University
Hypotension During Surgery
External Validation of Prediction Algorithm Using Non-invasive Monitoring Device for Intraoperative Hypotension
The goal of this prospective observational study is to externally validate the prediction algorithm using non-invasive monitoring device for intraoperative hypotension.
- Trial name
- NCT06897514
- Testing
- Prediction algorithm for intraoperative hypotension
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Samsung Medical Center
Sepsis, Hypotension
Non-Invasive Cardiac Output Monitor (NICOM) for Goal-directed Fluid Resuscitation for Inpatients With Hypotension and/or Septic Shock
The Non-Invasive Cardiac Output Monitor (NICOM) is a non-invasive monitor capable of measuring cardiac output (CO) and cardiac index (CI), and stroke volume (SV) and stroke volume index (SVI) based on heart rate.
- Conditions
- Sepsis, Hypotension, Septic Shock
- Trial name
- NCT05630716
- Testing
- NICOM
- Where
- United States
- Volunteers
- 251 people
- Sponsor
- University of Minnesota
Hypotension During Surgery
Epinephrine Infusion for Prophylaxis Against Maternal Hypotension After Spinal Anesthesia for Cesarean Delivery
Subarachnoid block is the common route of anesthesia for cesarean delivery. Maternal hypotension after subarachnoid block is very common despite the vigorous methods for its prevention.
- Trial name
- NCT05881915
- Testing
- Phenylephrine, Epinephrine
- Where
- Egypt
- Volunteers
- 196 people
- Sponsor
- Cairo University
Post Spinal Anaesthesia Hypotension, Geriatric Population
Effect of Dexamethasone on Post-spinal Hypotension
The goal of this clinical trial is to learn if intravenous dexamethasone is effective for prevention of post spinal hypotension in geriatric population undergoing orthopedic surgeries.
- Conditions
- Post Spinal Anaesthesia Hypotension, Geriatric Population, Orthopedic Surgeries
- Trial name
- NCT06819436
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Shaheed Mohtarma Benazir Bhutto Institue of Trauma
Hypotension, Cesarean Section Complications
Effect of Granisetron on Usage of Sympathomimetics During Caesarean Section
The aim of the present study is to quantify the dose and usage of sympathomimetics used in caesarean section.
- Trial name
- NCT03318536
- Testing
- Granisetron Hydrochloride, No Granisetron
- Where
- Germany
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
Post Induction Hypotension
Dose Responsive Study of Ringer's Lactate Solution in Prevention of Post-induction Hypotension
To assess the dose responsiveness of ringer lactate solution in prevention of post-induction hypotension predicted by Ultrasound guided Inferior Vena Cava diameter in patients receiving General anesthesia.
- Trial name
- NCT05924230
- Testing
- RL 10ml/kg, RL 15ml/kg
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tata Main Hospital
Hypotension
Phenylephrine for Spinal Induced Hypotension
This study is designed to determine the ED90 for a single dose of phenylephrine for the treatment of spinal induced hypotension in parturients presenting for an elective CD.
- Trial name
- NCT00781157
- Testing
- Phenylephrine bolus
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- IWK Health Centre
Hypotension
Median Sevoflurane Concentration for Hypotension Between Young and Elderlypatients: Adaptive Clinical Trial
Two arms: elder group, young group. Dixon's up and down adaptive methodology for ED50. Executed after Anesthesia induction for 10min without touching the patient after starting mechanical ventilation.
- Trial name
- NCT03595319
- Testing
- Sevoflurane
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Brasilia University Hospital
Hypotension, Fluid Therapy
Phenylephrine or Norepinephrine for a Better Hemodynamic Stability
A prospective, double-blinded study. The present study consisted in applying Stroke volume variation fluid guided therapy to old patients (65 years old) undergoing radical resection of colon surgery.
- Trial name
- NCT03215797
- Testing
- phenylephrine, Norepinephrine
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Dalian Medical University
the Effect of Hypotension Prediction Index Application
Hypotension Prediction Index in Major Gastrointestinal Surgery
Intraoperative hypotension (IOH) is defined as a mean arterial pressure (MAP) of < 65mmHg during surgery. Patients undergoing major gastrointestinal (GI) surgery, such as esophagectomy with reconstruction, are at a high-risk of…
- Trial name
- NCT04966364
- Testing
- hypotension prediction index guided, without hypotesion prediction index guided
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Severe Sepsis, Persistent Hypotension
Epidemiology of Septic Shock in Medical or Polyvalent ICU in the North-East Region of France
The epidemiology of this study aims and outcome of patients with septic shock in the intensive care unit (or versatile) of the North-East region in france as well as the modalities of care.
- Trial name
- NCT01903746
- Volunteers
- 1,495 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Total Fluid Volume Decreased
Preoperative Ultrasound Guided Evaluation of SVC-CI and IVC -CI as Predictors of Hypotension After Induction of Anaesthesia in Major Onco-surgery
Patients undergoing major Oncosurgeries are fluid deficit due to preoperative fasting , inadequate intake due to disease hence prone to development of hypotension after induction of general anaesthesia owing to vasodilatory…
- Trial name
- SVC IVC CI (NCT05548920)
- Testing
- Ultrasound guided Superior Vena Cava Collapsibility Index, Inferior Vena Cava Collapsibility Index
- Where
- India
- Volunteers
- 120 people
- Sponsor
- Rajiv Gandhi Cancer Institute & Research Center, India
Hypotension on Induction
Carotid Artery Corrected Flow Time and Respiratory Variation of Blood Flow Peak Velocity for Prediction of Hypotension After Induction of General Anaesthesia in Adult Patients With Chronic Liver Disease
Baseline Measurements For the ultrasound parameters, it is the average of three readings In supine position . The investigators will continuously monitoring during induction and 10 minutes after.
- Trial name
- NCT07370103
- Where
- Egypt
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Spinal Induced-hypotension
Comparison of Phenylephrine and Norepinephrine for Spinal-induced Hypotension
Hypotension after spinal anaesthesia for cesarean deliveries is frequently encountered. Phenylephrine an α-agonist is commonly used for the prevention and treatment of spinal-induced hypotension.
- Trial name
- NCT04789005
- Testing
- Norepinephrine, Phenylephrine
- Where
- Nepal
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tribhuvan University Teaching Hospital, Institute Of Medicine.