Clinical trials: Arterial Hypotension
Hypotension
Transcutaneous Electrical Acupoint Stimulation(TEAS) for Hypotension After Spinal Anesthesia in Parturients
The purpose of this study is to compare the effect of TEAS on hypotension after spinal anesthesia in patients undergoing cesarean section
- Trial name
- THSAP (NCT01930227)
- Testing
- TEAS, Non-acupoint stimulation
- Where
- 2 sites in China
- Volunteers
- 150 people
- Sponsor
- wangqiang
Hypotension
Interest of Intravenous Ondansetron in the Prevention of Spinal Anaesthesia-induced Hypotension in Caesarean Section
The intravenous injection of 8mg of ondansetron (a serotonin type 3 receptor antagonist) before spinal anaesthesia for caesarean section, leads to a smaller reduction in systolic arterial pressure (SAP).
- Trial name
- ZORA (NCT02862873)
- Testing
- Spinal anaesthesia, Ondansetron, saline solution
- Where
- France
- Volunteers
- 7 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Hypotension
Ultrasound in Undifferentiated Hypotension
Background Symptomatic undifferentiated hypotension represents a negative prognostic factor and the strongest predictor of in-hospital mortality.
- Trial name
- US-UHP (NCT01572571)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- San Luigi Gonzaga Hospital
Spinal Induced Hypotension, Geriatric Population
Spinal-Induced Hypotension in Geriatric Patients
The study will be conducted to asses preoperative condition of venous system by VExUS score and it's relation with the incidence of spinal induced hypotension in geriatric patients undergoing surgery with spinal anaesthesia.
- Conditions
- Spinal Induced Hypotension, Geriatric Population, Intravascular Volume
- Trial name
- NCT05862298
- Testing
- venous excess ultrasound score
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Tanta University
Intraoperative Hypotension, Hepatectomy
Remimazolam Versus Propofol for Maintenance of Anaesthesia During Major Hepatectomy Under Low Central Venous Pressure
The goal of this clinical trial is to learn whether remimazolam helps prevent low blood pressure better than propofol during major liver surgery in adults.
- Trial name
- NCT07789275
- Testing
- Remimazolam, Propofol
- Where
- China
- Volunteers
- 224 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Hypotension
A Novel Closed-loop Integrated System for the Maintenance of Haemodynamic Stability
Hypotension occurs commonly during spinal anaesthesia for caesarean section with maternal and fetal adverse effects. The investigators developed a double-vasopressor automated system incorporating continuous non-invasive…
- Trial name
- DIVA (NCT02277730)
- Testing
- vasopressor delivery automated system, phenylephrine, ephedrine
- Where
- Singapore
- Volunteers
- 252 people
- Sponsor
- KK Women's and Children's Hospital
Breast Tumors, Hypotension
Levobupivacaine and Lidocaine for Paravertebral Block Causes Greater Hemodynamic Oscillations Than Levobupivacaine
The purpose and the goal of this paper is to show whether the application of a combination of two local anesthetics, as opposed to the application of one local anesthetic at paravertebral block changes the hemodynamic variable.
- Conditions
- Breast Tumors, Hypotension, Bradycardia
- Trial name
- NCT02004834
- Testing
- levobupivacaine
- Where
- Croatia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital Dubrava
Hypotension, Shock
Fluid Responsiveness Prediction at the Bedside
The purpose of this study is to verify the accuracy and applicability of predictors of fluid administration efficacy in hypotensive critically ill patients.
- Trial name
- NCT00721604
- Testing
- fluid administration
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione Poliambulanza Istituto Ospedaliero
Hemodialysis, Diabetes
Analysis of Influencing Factors of Hypotension in Diabetic Patients Undergoing Dialysis
Hypotension (IDH) during dialysis is a common complication in hemodialysis, and the incidence is 20-50% in hemodialysis patients, the proportion of diabetic patients with IDH is 26.7%, which is much higher than that of…
- Trial name
- NCT05325892
- Testing
- This is an observational study
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Beijing Friendship Hospital
Neurogenic Orthostatic Hypotension
Spinal Cord Stimulation for Neurogenic Orthostatic Hypotension
Neurogenic orthostatic hypotension is a disabling manifestation of synucleinopathies including Parkinson's disease, multiple system atrophy, dementia with Lewy bodies, and pure autonomic failure.
- Trial name
- NCT07879391
- Testing
- Lower thoracic epidural spinal cord stimulation
- Volunteers
- 20 people
- Sponsor
- Aerospace Center Hospital
Hypotension During Surgery
Controlled Hypotension in Rhinoplasty and Septoplasty: Incidence of Cognitive Dysfunction and Delirium
Controlled hypotension application is a commonly preferred anesthesia practice during surgical procedures, particularly in regions with rich tissue perfusion, aiming to reduce bleeding, enhance surgical field visibility, and…
- Trial name
- NCT06238973
- Testing
- Group Low, Group Middle
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Hitit University
Secondary Adrenal Insufficiency, Hypotension
Ramadan Fasting Outcomes in Patients With Secondary Adrenal Insufficiency Before and After the Treatment of Hypotension.
Intermittent fasting in patients with adrenal insufficiency is associated with an increased risk of complications, such as dehydration.
- Trial name
- NCT06832566
- Testing
- Fludrocortisone 0.1 Milligrams (mg)
- Where
- Tunisia
- Volunteers
- 20 people
- Sponsor
- Hopital La Rabta
Multiple System Atrophy - Parkinsonian Subtype (MSA-P), Multiple System Atrophy - Cerebellar Subtype (MSA-C)
PET Imaging Study of Neurochemical and Autonomic Disorders in Multiple System Atrophy (MSA)
Multiple system atrophy (MSA) is a disorder of the nervous system of unclear cause. In MSA there is degeneration (progressive loss) of nerve cells in several brain and spinal cord regions.
- Trial name
- NCT02035761
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Michigan
Hemodynamic Monitoring
The EU Hyprotect Registry
European, multicenter, prospective, observational registry in patients undergoing elective major non-cardiac surgery
- Trial name
- NCT04972266
- Testing
- AcumenTM Hypotension Prediction Index software
- Where
- 12 sites in France, Germany and 3 more
- Volunteers
- 702 people
- Sponsor
- Edwards Lifesciences
Sepsis
Study of Treatment's Echocardiographic Mechanisms
This ancillary study determines whether the Crystalloid Liberal or Vasopressors Early Resuscitation in Sepsis (CLOVERS) [ClinicalTrials.gov Identifier: NCT03434028] treatment arms (restrictive fluids strategy vs.
- Trial name
- NCT03913403
- Testing
- ECHO, Blood Draw
- Where
- 7 sites in United States
- Volunteers
- 210 people
- Sponsor
- Intermountain Health Care, Inc.
Hypotension During Surgery, Blood Loss, Surgical
Reducing Hypotensive Anesthesia Use With TXA During Orthognathic Surgery
This prospective study will analyze the need for deliberate hypotensive anesthesia (DHA) during orthognathic surgery when tranexamic acid (TXA) is administered.
- Trial name
- NCT05474027
- Testing
- Avoidance of Deliberate Hypotensive Anesthesia, TRANEXAMIC ACID 1 G in 10 mL INTRAVENOUS INJECTION, SOLUTION
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Hypotension
Propofol vs. Ciprofol for Anesthesia Induction in Frail Elderly Patients
Post-induction hypotension (PIH) is a common and critical complication during general anesthesia, particularly in frail elderly patients whose physiological reserves are significantly diminished.
- Trial name
- NCT07663695
- Testing
- Ciprofol, Propofol
- Where
- China
- Volunteers
- 96 people
- Sponsor
- General Hospital of Ningxia Medical University
Catecholamine-resistant Hypotension (CRH), Distributive Shock
A Study of LJPC-501 in Pediatric Patients With Hypotension
The objective of this study is to evaluate the effect of LJPC-501 infusion on mean arterial pressure (MAP) or reduction in sum norepinephrine (NE) equivalent dosing, at Hour 2 after the start of LJPC-501, in pediatric patients…
- Conditions
- Catecholamine-resistant Hypotension (CRH), Distributive Shock, High Output Shock, Sepsis
- Trial name
- NCT03431077
- Testing
- Angiotensin II
- Where
- 3 sites in United States
- Volunteers
- 2 people
- Sponsor
- La Jolla Pharmaceutical Company
Post-induction Hypotension, Post Anesthesia Recovery
Intraoperative Hypotension and Post-anesthesia Care Unit Recovery
The underlying causative mechanism that leads to intraoperative hypotension (IOH) may vary depending on the stage of anesthesia and surgery, which determines different IOH types.
- Conditions
- Post-induction Hypotension, Post Anesthesia Recovery, Hypotension, Intraoperative Hypotension
- Trial name
- NCT05671783
- Testing
- Hemodynamic observation of the patients.
- Where
- Turkey (Türkiye)
- Volunteers
- 4,776 people
- Sponsor
- Acibadem University
Hypotension After Spinal Anesthesia
Lingual Ondansetron in Reduction of Spinal Hypotension in Cesarean Section
The goal of this clinical trial is to learn if drug ondansetron, used in lingual form, lowers the incidence of spinal anesthesia-induced hypotension in cesarean sections. It will also learn about the safety of drug ondansetron.
- Trial name
- NCT07037654
- Testing
- ondansetron lingual film
- Where
- Egypt
- Volunteers
- 112 people
- Sponsor
- Suez Canal University
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