Clinical trials: Arterial Hypotension
Head-Down Tilt Following Spinal Anesthesia
Cephalic Spread of Block With Head Down Tilt in Spinal Anaesthesia - A Randomised Controlled Study
Subarachnoid block has become an established and reliable method of providing anaesthesia for lower abdominal and lower limb surgeries. Several factors determine the spread of local anaesthetic solutions in CSF.
- Trial name
- NCT03491319
- Testing
- Group X - head low tilt, Group Y - head low tilt, Group C - neutral
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nitte University
Pregnancy, Effects of; Anesthesia, Spinal and Epidural; in Pregnancy
Effect of Different Injection Speeds for Spinal Anaesthesia in Caesarean Section
The purpose of this study is to investigate if prolonging the speed of injection during spinal anaesthesia can reduce the incidence of hypotension and/or medication requirements thereby making it safer for the mother and foetus.
- Trial name
- NCT02275897
- Testing
- Slow Speed of spinal injection, Fast Speed of spinal injection
- Where
- Malaysia
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Malaysia
Cardiac Arrest, Out-Of-Hospital, Hypotension
Cardiac Arrest - Ultrasound Detection of Occult Perfusion
The goal of this study is to describe the population of patients presenting after out of hospital cardiac arrest with occult perfusion, defined as a patient without a palpable pulse but with some evidence of pulsatile arterial…
- Trial name
- NCT07897370
- Where
- 8 sites in United States
- Volunteers
- 1,400 people
- Sponsor
- University of Massachusetts, Worcester
Intraoperative Bleeding, Functional Endoscopic Sinus Surgeries
Dexmedetomidine Versus Nitroglycerin on Surgical Field Quality and Drug Cost in Functional Endoscopic Sinus Surgeries
Sinus surgery is one of the most prevalent ear, nose, and throat (ENT) surgeries, which is mainly carried out nowadays through functional endoscopic sinus surgery (FESS) and leads to significant improvement in the clinical…
- Conditions
- Intraoperative Bleeding, Functional Endoscopic Sinus Surgeries, Hypotension
- Trial name
- NCT07585201
- Testing
- controlled hypotension using dexmedetomidine, controlled hypotension hypotension using nitroglycerin
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Zagazig University
Functional Endoscopic Sinus Surgery
Comparison Between Pregabalin and Magnesium Sulfate in Hypotensive Anaesthesia
Comparison between pregabalin and magnesium sulfate in hypotensive anaethesia
- Trial name
- NCT05442931
- Testing
- Pregabalin 150mg, Magnesium Sulfate, Nitroglycerin
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Minia University
End Stage Renal Disease, End Stage Renal Disease on Dialysis
Evaluation of Non-Invasive Continuous vs Intermittent BloodPressure Monitors in Maintenance Dialysis (BP Dialysis)
Prospective, single center, open label, non-randomized, post-market study of the Tablo Hemodialysis System and VitalStream Monitor in participants with End-Stage KidneyDisease undergoing In-Center Hemodialysis.
- Conditions
- End Stage Renal Disease, End Stage Renal Disease on Dialysis, Dialysis Hypotension, Dialysis Induced Hypertension
- Trial name
- NCT05540457
- Testing
- Intermittent Non-InvasiveBlood Pressure Monitor
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The Rogosin Institute
Anesthesia
Ultrasonic Measurement of IVC and IJV in Predicting Hypotension After Anesthesia Induction
This research is expected to study ultrasonic measurement of internal jugular vein and inferior vena cava, which can be used as a good index to predict hypotension after anesthesia induction, and its measurement method is simple…
- Trial name
- NCT04379141
- Volunteers
- 150 people
- Sponsor
- Jin Dong Liu
Anesthesia, Surgery
Norepinephrine vs Phenylephrine During General Anesthesia
50 million patients undergo surgery each year in the United States. Postoperative mortality is considered the third leading cause of death worldwide.
- Conditions
- Anesthesia, Surgery, Hypotension
- Trial name
- VEGA-1 (NCT04789330)
- Testing
- Norepinephrine, Phenylephrine
- Where
- 5 sites in United States
- Volunteers
- 3,626 people
- Sponsor
- University of California, San Francisco
Hypotension, Spinal Anesthesia
Prophylactic Ondansetron for Preventing Spinal Anesthesia-Induced Hypotension in Elective Cesarean Section
Spinal anesthesia is the preferred technique for elective cesarean section, but it frequently causes maternal hypotension due to sympathetic blockade and the Bezold-Jarisch reflex, which can threaten both mother and baby.
- Conditions
- Hypotension, Spinal Anesthesia, Cesarean Section
- Trial name
- NCT07886151
- Testing
- Ondansetron
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Spinal Anesthesia, Pregnancy
Ephedrine vs Phenylephrine - ECG Changes
ECG changes during caesarean section are common. Incidence of ST depression on the ECG is up to 81% in some studies. Although this may indicate inadequate oxygen supply to the heart muscle (myocardial ischaemia) many other…
- Trial name
- NCT01243970
- Testing
- Phenylephrine, Ephedrine
- Where
- United Kingdom
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University College London Hospitals
Cesarean Section
Heart Rate Variability to Predict Hypotension Following Spinal Anesthesia in Cesarean Delivery
Based on the patient's heart rate variability, the analgesia nociception index (ANI) measures the activity of the autonomic nervous system and the sympathetic/parasympathetic nervous system and expresses it as a numerical value…
- Trial name
- NCT04979039
- Testing
- analgesia nociception index (ANI) monitoring
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Bundang Hospital
Apheresis Related Hypotension
Evaluation of the Aurora Xi New Nomogram Software 2.0
A clinical trial to evaluate the safety and effectiveness of the Aurora Xi Plasmapheresis System with a new plasma collection volume nomogram.
- Trial name
- NCT06122935
- Testing
- Aurora Xi New Nomogram Software 2.0, Aurora Xi Currently Approved Software 1.3
- Where
- 3 sites in United States
- Volunteers
- 6,735 people, healthy volunteers welcome
- Sponsor
- Fenwal, Inc.
Hypertension
Post-exercise Hypotension After a Power Training Session in Older Adults With Hypertension
The main purpose of the present study was to evaluate the effect of a power training session on office and 24h ambulatory blood pressure in older adults with hypertension.
- Trial name
- NCT03615625
- Testing
- Power Training Session
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Anesthesia, General, Hypotension
Can Continuous Cardiac Output Monitoring Before General Anesthesia Predict Hypotension After Induction?
Post-induction hypotension (PIH) is very common with high incidence about 9-60%. There are multiple factors that may cause PIH, like pre-operative fasting, bowel preparation, vasodilatation due to anesthetics, and reduced…
- Conditions
- Anesthesia, General, Hypotension, Cardiac Output
- Trial name
- NCT03718949
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Hypotension on Induction
CirQPOD Shoulder Study
Intrathoracic pressure regulation (IPR) therapy, delivered by impedance threshold devices (ITDs) or intrathoracic pressure regulators (ITPRs), increases venous return, preload, cardiac output, blood pressure, and cerebral…
- Trial name
- NCT04299776
- Testing
- CirQPOD, Standard airway management
- Where
- United States
- Sponsor
- Zoll Medical Corporation
Blood Pressure, Hypotension Drug-Induced
Comparison Between Inhalation and Intravenous Induction of Anaesthesia During Interventional Mitral Valve Repair
The induction of anaesthesia is one of the most critical situations for high-risk-patients undergoing interventions surgery. For several reasons, it is crucial to maintain adequate blood pressure and cardiac output during this…
- Trial name
- COMPETENT (NCT04865614)
- Testing
- Etomidate, Sevoflurane
- Where
- Germany
- Volunteers
- 57 people
- Sponsor
- Heidelberg University
Multiple Myeloma
A Study Evaluating Hypotension and Autonomic Nervous System Dysfunction in Multiple Myeloma (MM) Patients
The purpose of this study is to determine whether the orthostatic hypotension reported among subjects during bortezomib-containing regimen is caused by a dysfunction of the autonomic nervous system (ANS).
- Trial name
- NCT01314625
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Arkansas
Sepsis, Septic Shock
Early Norepinephrine Administration and Rapid Dose Adjustment
The goal of this clinical trial is to determine whether early initiation of norepinephrine with rapid dose adjustment improves clinical outcomes in adult patients with septic shock.
- Trial name
- CENSER2 (NCT07343206)
- Testing
- Early norepinephrine administration and rapid dose adjustment, Control
- Where
- 6 sites in Thailand
- Volunteers
- 600 people
- Sponsor
- Siriraj Hospital
Hypotension During Surgery
Epinephrine Infusion for Prophylaxis Against Maternal Hypotension After Spinal Anesthesia for Cesarean Delivery
Subarachnoid block is the common route of anesthesia for cesarean delivery. Maternal hypotension after subarachnoid block is very common despite the vigorous methods for its prevention.
- Trial name
- NCT05881915
- Testing
- Phenylephrine, Epinephrine
- Where
- Egypt
- Volunteers
- 196 people
- Sponsor
- Cairo University
Spinal Induced Hypotension
PVI for Prediction of Spinal Induced Hypotension
The hypothesis is that plethysmography variability index can predict the occurrence of hypotension after spinal anesthesia for cesarean delivery
- Trial name
- NCT01967914
- Testing
- PVI
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Duke University
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