Clinical trials: Arterial Hypotension
Anesthesia
Tachycardia as an Indication for Prophylactic Phenylephrine Injection in Caesarean Section Under Spinal Anesthesia; an Observational Study
The value of phenylephrine administration in response to tachycardia in preventing hypotension after spinal anesthesia in elective cesarean section.
- Trial name
- NCT06220942
- Testing
- Phenylephrine
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Hypotension, Very Low Birth Weight Infants
N-Terminal Pro-B-Type Natriuretic Peptide and Troponin Levels as Markers of Hemodynamic Stability in Very Low Birth Weight Infants During the First Days of Life
The primary objective is to test the hypothesis that there is an association between the hemodynamic status and the serum levels of NT-proBNP and cTnT in prematurely born infants.
- Conditions
- Hypotension, Very Low Birth Weight Infants, Ventricular Dysfunction, Prematurity
- Trial name
- NCT00425581
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Hypotension, Cesarean Section Complications
Effect of Granisetron on Usage of Sympathomimetics During Caesarean Section
The aim of the present study is to quantify the dose and usage of sympathomimetics used in caesarean section.
- Trial name
- NCT03318536
- Testing
- Granisetron Hydrochloride, No Granisetron
- Where
- Germany
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
General Anesthesia Induction for Elective Surgery
Carotid Artery Corrected Flow Time as a Predictor of Hypotension After Induction of General Anesthesia in Elderly Patients
The number of elderly patients undergoing elective surgery has been growing in recent years. Elderly patients often have a variety of underlying diseases, including hypertension, coronary heart disease, diabetes…
- Trial name
- NCT05628051
- Testing
- ultrasonographic measurement of carotid artery corrected flow time (FTc)
- Where
- China
- Volunteers
- 177 people
- Sponsor
- Fujian Medical University Union Hospital
Hypotension on Induction
Comparative Efficacity of Ephedrine Versus Norepinephrine to Correct Anesthesia Induction Related Hypotension
Hypotension occurs frequently after anesthesia induction and is more frequent in patients with chronic renal insufficiency. This hypotension occurs most frequently during the 20 minutes after anesthesia induction.
- Trial name
- NCT05497700
- Testing
- Ephedrine, Norepinephrine
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Brugmann University Hospital
Coronary Artery Bypass Grafting, Hypotension
The PRESSURE CABG Cardiac Surgery Trial
This study will be a pragmatic, prospective, single-centre, unit-based cluster crossover, open-label registry trial. The cardiac surgical intensive care unit (CSICU) will be cluster assigned to alternating MAP targets in 6-month…
- Trial name
- PRESSURECABG (NCT04197700)
- Testing
- Target MAP Management
- Where
- Canada
- Volunteers
- 600 people
- Sponsor
- University of Alberta
Hypotension, Ischemia
Phase III Study of Hemospan® to Prevent Hypotension in Hip Arthroplasty
The purpose of this study is to determine whether Hemospan is superior to Voluven for preventing hypotensive episodes during the perioperative period (from induction of spinal anesthesia until 6 hours after skin closure), and for…
- Trial name
- NCT00421200
- Testing
- Hemospan (MP4OX), Voluven (HES 130/0.4)
- Where
- 18 sites in Belgium, Czechia and 4 more
- Volunteers
- 375 people
- Sponsor
- Sangart
Hypotension Drug-Induced, General Anesthesia Using Endotracheal Intubation
Alveolar Recruitment Maneuver-Induced Hypotension: A Dynamic Consequence and Intraoperative Indicator of Fluid Responsiveness
This study investigates whether two simple bedside tests - the Passive Leg Raising (PLR) test and the Pleth Variability Index (PVI) - can predict a drop in blood pressure that sometimes occurs during a lung-opening procedure…
- Conditions
- Hypotension Drug-Induced, General Anesthesia Using Endotracheal Intubation, Atelectasis, Fluid Responsiveness
- Trial name
- NCT07766967
- Testing
- Alveolar Recruitment Maneuver (ARM), Passive Leg Raising (PLR) Test
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- University of Health Sciences Balikesir Hospital Eduation and Research
Obstetric Anesthesia Problems
The Ability of the Change in Positional Perfusion Index in Predicting Post-spinal Anesthesia Hypotension in Caesarian Section
Our study aims to investigate the value of postural perfusion index changes as a non-invasive method to predict hypotension following spinal anesthesia for elective cesarean delivery.
- Trial name
- NCT05269407
- Testing
- Peripheral perfusion index
- Where
- Egypt
- Volunteers
- 115 people
- Sponsor
- Cairo University
Hypotension on Induction
Hypotension in Children With Down Syndrome With Anesthesia Induction
Children generally undergo induction of anesthesia by inhalation of sevoflurane. Children with Down Syndrome experience bradycardia with induction of anesthesia using sevoflurane.
- Trial name
- NCT04603469
- Testing
- Non invasive blood pressure
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Baylor College of Medicine
Renal Transplant Failure and Rejection, Hypotension
HOW DOES HEMODYNAMIC REGULATION AFFECTS GRAFT FUNCTIONS DURING RENAL TRANSPLANTATION?
The aim of the researchers was to evaluate the adequacy of graft function in the postoperative period of patients who underwent renal transplantation and encountered hypotension in the intraoperative period.
- Trial name
- NCT05753475
- Testing
- renal transplantation
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Autonomic Nervous System Diseases, Orthostatic Hypotension
Treatment of Orthostatic Hypotension
The purpose of this study is to try different medications in patients with low blood pressure and other problems with their involuntary (autonomic) nervous system.
- Conditions
- Autonomic Nervous System Diseases, Orthostatic Hypotension, Dopamine Beta-Hydroxylase Deficiency, Orthostatic Intolerance
- Trial name
- NCT00581477
- Testing
- Droxidopa Oral Product
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Vanderbilt University
Hemodialysis, Intradialytic Hypotension
Different Ultrafiltration Rates and Intradialytic Hypotension.
Finding relationship between different ultrafiltration rates and intradialytic hypotension in attempt to find the optimal cut off points.
- Trial name
- NCT06695923
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Sohag University
Intradialytic Hypotension, Hypervolemia
Pilot Study Using a Pulse Oximeter Derived Photo-plethysmographic Waveform to Guide Hemodialysis Ultrafiltration
The purpose of this study is to use the photo-plethysmographic [PPG] waveform signal to guide the dialysis and ultrafiltration [UF] of chronic maintenance hemodialysis patients, and to further the investigators understanding of…
- Trial name
- NCT02264522
- Testing
- Place dialysis chair into position 3., Decrease dialysate temperature., Decrease ultrafiltration rate by 25%.
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Intelomed, Inc.
Autonomic Failure, Orthostatic Hypotension
Abdominal Compression in Orthostatic Hypotension
The purpose of this study is to assess if abdominal binders that use pull strings to adjust compression (non-elastic) are more effective than standard elastic abdominal binders in attenuating neurogenic orthostatic hypotension.
- Trial name
- NCT01223391
- Testing
- Abdominal binder, No abdominal binder
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Mayo Clinic
Intraventricular Hemorrhage, Autoregulation
Physiological Disturbances Associated With Neonatal Intraventricular Hemorrhage
Annually, almost 5,000 extremely low birth weight (9 ounces to about 2 lbs) infants born in the US survive with severe bleeding in the brain (intraventricular hemorrhage); this devastating complication of prematurity is…
- Trial name
- PhysDis (NCT00665769)
- Testing
- Hypercapnia, Normocapnia
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Baylor College of Medicine
Hypotension, Fontan Physiology
The Hemodynamic Effects of Vasopressin in Patients With Fontan Physiology
The goal of this study is to evaluate if vasopressin can elevate systemic arterial blood pressures without having a significant effect on pulmonary arterial pressures.
- Trial name
- NCT04463394
- Testing
- Vasopressin
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- Stanford University
The iNPH Patients Scheduled for VP or LP Shunt Procedures
Factors Associated With Post-induction Hypotension in iNPH Patient Undergoing VP and LP Shunt
This study is a retrospective work involving the review of patients who were scheduled for VP or LP shunt in Siriraj Hospital, Mahidol University, Thailand.
- Trial name
- NCT05183061
- Testing
- Ehedrine Norepineprine
- Where
- Thailand
- Volunteers
- 426 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Hypotension During Dialysis, Dialysis Hypotension
Integrated Strategies to Prevent Intradialytic Hypotension (The DialHypot Study)
The present study is aimed at comparing different strategies of UF profiling, dialysate sodium individualization and sodium profiling (even combining one with the other) and at evaluating the effectiveness of a new UF profile…
- Trial name
- DialHypot (NCT03949088)
- Testing
- UF and Na profiling
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Parma
Patients Undergoing Neurosurgery
The Comparison of Hypotension Incidence Between Remimazolam and Propofol in Hypertensive Patients Undergoing Neurosurgery
This study aims to find an excellent drug in terms of hemodynamic stability when comparing the propofol and remifentanil with the combined use of remimazolam and remifentanil.
- Trial name
- NCT05164146
- Testing
- propofol, remimazolam
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yonsei University
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