Clinical trials: Arterial Hypotension
Drug-induced Hypotension
Study of Maraviroc (MVC) and Epzicom (ABC/3TC) Once-Daily in ART-Naive & First Switch Patients
Hypotension does not occur with Maraviroc at a dose of 600 mg/day
- Trial name
- NCT02626923
- Volunteers
- 51 people
- Sponsor
- Nicholaos C Bellos, MD
Acute Kidney Injury, Renal Replacement Therapy
Albumin To Enhance Recovery After Acute Kidney Injury
Study objectives: To determine whether, in critically ill patients with Acute Kidney Injury requiring renal replacement therapy (AKI-RRT), randomization to receive intravenous hyperoncotic albumin 20-25% (100 mL X two doses)…
- Conditions
- Acute Kidney Injury, Renal Replacement Therapy, Hypotension, Critical Illness
- Trial name
- ALTER-AKI (NCT04705896)
- Testing
- 20-25% Albumin fluid (100 mL), 0.9% Normal Saline (100 mL)
- Where
- 16 sites in Canada
- Volunteers
- 856 people
- Sponsor
- Ottawa Hospital Research Institute
Hypotension During Surgery, Kidney Transplant; Complications
Hypotension Prediction With HPI Algorithm During Decessed-donor Kidney Transplant (HPI2022)
HPI monitoring and the adoption of therapeutic interventions before hypotension occurs should be ensure a shorter time of intra-operative hypotension (MAP < 65 mmHg) during deceased-donor kidney transplant surgery.
- Trial name
- HPI2022 (NCT05394896)
- Testing
- ACUMEN (Edwards Lifesciences, Irvine, USA), Invasive Blood Pressure
- Where
- Italy
- Volunteers
- 46 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Nasal Surgery, Anesthesia
Remifentanil vs. Nicardipine for Controlled Hypotension in Elective Nasal Surgery
This study compares remifentanil infusion versus nicardipine infusion for controlled hypotension during elective nasal surgery. Both agents are standard clinical methods.
- Conditions
- Nasal Surgery, Anesthesia, Controlled Hypotension for Nasal Surgeries
- Trial name
- NCT07660562
- Testing
- Nicardipine, Remifentanil
- Volunteers
- 44 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Spinal Cord Injuries, Postprandial Hypotension
Low-GI Diet Vs High-GI Diet in Individuals with SCI
The purpose of this pilot research project is to examine the impact of a low-glycemic index (GI) diet on postprandial hypotension and glucose control in individuals with chronic spinal cord injury.
- Conditions
- Spinal Cord Injuries, Postprandial Hypotension, Glucose Metabolism Disorders
- Trial name
- NCT05334342
- Testing
- Low-GI Diet, High-GI Diet
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Ohio State University
Kidney Failure
To Assess Ear Blood Flow During Dialysis
This is a prospective observational pilot study of patients under the care of the Royal Free Hospital with chronic kidney disease who have been established on regular thrice weekly haemodialysis treatments in a dialysis centre,to…
- Trial name
- NCT02545920
- Testing
- no intervention
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- University College, London
Hypotension During Surgery
Hypotension Prediction Index for Shoulder Surgery in Beach Chair.
The beach chair position is the most commonly used position during shoulder surgery and offers the surgeon numerous advantages over the lateral decubitus position.
- Trial name
- NCT06120296
- Testing
- Acumen Hypotension prediction Index software
- Where
- Belgium
- Volunteers
- 144 people
- Sponsor
- Geertrui Dewinter
Blood Pressure, Perioperative Hypotension
Impact of Continuous Non-invasive Blood Pressure Monitoring on Hypotension in Patients Having Non-cardiac Surgery
This is a randomized trial (1) investigating whether continuous non-invasive finger-cuff blood pressure monitoring reduces the area under a mean arterial pressure (MAP) of 65 mmHg within the first 15 minutes of anesthetic…
- Trial name
- NCT04736862
- Testing
- Continuous non-invasive blood pressure monitoring, Intermittent non-invasive blood pressure monitoring
- Where
- Germany
- Volunteers
- 242 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Blood Pressure, Low
Induction Agent and Incidence of Hypotension in Heart Failure Patients Undergoing LVAD-Implantation
The induction of anesthesia is one of the most critical situations for high-risk-patients undergoing major surgery. For several reasons, it is crucial to maintain adequate blood pressure and cardiac output during this phase.
- Trial name
- INTENS (NCT04934410)
- Testing
- Etomidate, Midazolam, Sevoflurane
- Volunteers
- 50 people
- Sponsor
- Heidelberg University
Intraoperative Hypotension
Continuous Finger-cuff Arterial Pressure Monitoring and Intraoperative Hypotension During Non-cardiac Surgery: the Randomized DETECT II Trial
This is a randomized trial (1) investigating whether continuous finger-cuff - compared to intermittent oscillometric - arterial pressure monitoring reduces the amount of intraoperative hypotension (specifically, from the start of…
- Trial name
- DETECT II (NCT06753097)
- Testing
- Continuous finger-cuff arterial pressure monitoring
- Where
- Germany
- Volunteers
- 930 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Hypotension, Respiratory Failure
Thyroid Hormones in Critically Ill Children
Thyroid hormones are substances naturally made by the body and are important to many of your body's basic functions such as breathing and brain function.
- Trial name
- Thyroid (NCT00664079)
- Testing
- Blood draws
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Children's Hospital of Philadelphia
Hypertrophic Obstructive Cardiomyopathy
The Safety and Influencing Factors of Liwen Procedure in The Treatment of Hypertrophic Cardiomyopathy
Liwen procedure is generally safe and effective in treating hypertrophic cardiomyopathy, but a small proportion of patients have complications after the operation.
- Trial name
- NCT06003478
- Testing
- Percutaneous Intramyocardial Septal Radiofrequency Ablation for hypertrophic obstructive cardiomyopathy (Liwen Procedure)
- Where
- China
- Volunteers
- 486 people
- Sponsor
- Xijing Hospital
Complications; Cesarean Section, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Phenylephrine Dose and Mode of Administration for Spinal Anesthesia Induced Hypotension
Three different regimens of phenylephrine are being evaluated to see if one is superior over the other in the maintenance of cardiac output while keeping normotension and/or treating hypotension experienced when receiving spinal…
- Trial name
- NCT02101047
- Testing
- Phenylephrine
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Intradialytic Hypotension, End Stage Renal Disease
Application of Impedance Threshold Device Technologies to Treat and Prevent Hypotension During Dialysis
The purpose of this study is to evaluate the application of the impedance threshold device during hemodialysis in children to optimize fluid removal, reduce the incidence of complications (such as cramps,vomiting and…
- Conditions
- Intradialytic Hypotension, End Stage Renal Disease, Low Blood Pressure
- Trial name
- ITD (NCT00576524)
- Testing
- ITD
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Children's Hospital of Philadelphia
Hypertension
Post-Exercise Hypotension in Elderly Hypertensive Men
The purpose of this study is to compare the effects of two exercise protocols on post-exercise blood pressure versus a control group in elderly hypertensive men.
- Trial name
- HPE (NCT02415582)
- Testing
- Aerobic exercise, Combined exercises, Control
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Surgery
Permissive Hypotension After Cardiac Surgery
The objective of this pilot randomized controlled trial is to demonstrate the feasibility of implementing a pragmatic clinical trial randomizing patients to permissive hypotension versus usual care and to determine the impact of…
- Trial name
- PHACS (NCT06476613)
- Testing
- Permissive Hypotension
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Massachusetts General Hospital
Hypertension, Hypoxia
The VISION-Acute Study
AIM: We propose an innovative approach using Lifelight® smart technology that will enable the continued provision of high level patient care at the same time as reducing pressure on nursing and equipment resources.
- Conditions
- Hypertension, Hypoxia, Hypotension
- Trial name
- NCT04589923
- Testing
- Lifelight® Data Collect Blood Pressure Group, Lifelight® Data Collect Oxygen Saturation Group
- Where
- United Kingdom
- Volunteers
- 127 people
- Sponsor
- Xim Limited
Hypertension
Clinical Validation of the Tiba Medical Ambulo 2400 ABPM According to the ISO 80601-2-30 Standard in Adults, Adolescents, and Children
Clinical validation of the Tiba Medical Ambulo 2400 ambulatory blood pressure monitoring system according to the accuracy guidelines of the ISO 80601-2-30 Standard in Adults, Adolescents, and Children.
- Trial name
- NCT00944983
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Tiba Medical, Inc.
Hemodialysis, Hypotension
Safety of Dialysate Sodium Individualization in Hemodialysis Patients With Intradialytic Hypotension
Low blood pressure (hypotension) during dialysis afflicts approximately 25% of hemodialysis patients. In this pilot study, we will evaluate the safety and effects of individualizing the sodium concentration in the dialysate…
- Trial name
- NCT00237783
- Testing
- dialysate sodium (140 mmol/L), individualized dialysate sodium
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Yale University
Orthostatic Hypotension
State of Knowledge Among Nurses Regarding the Screening for Orthostatic Hypotension in Elderly Individuals in Acute Geriatric Medicine and Medical and Rehabilitation Services
Orthostatic hypotension is a common geriatric syndrome associated with an increased risk of falls, syncope, functional decline and mortality in older adults.
- Trial name
- HTO-IDE (NCT07738666)
- Testing
- Administration of questionnaires on nurses' knowledge of orthostatic hypotension, its measurement, diagnosis and management
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hôpital NOVO
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