Clinical trials: Arterial Hypotension
Hypotension, Cardiopulmonary Bypass
Pharmacokinetics and Pharmacodynamics of MTR105 in Hypotensive Cardiac Surgery Patients
The purpose of this study is to evaluate the safety, pharmacokinetic and the pharmacodynamic effects of escalating doses of MTR105 while weaning from bypass in a hypotensive population of cardiac surgery patients.
- Trial name
- NCT00482287
- Testing
- MTR105
- Where
- United States
- Sponsor
- Meditor Pharmaceuticals Ltd.
Cesarean Section Complications
Perfusion Index and Pleth Variability Index in Cesarean Section.
The aim of this study is to investigate the predictability of hypotension by using PI and PVI in pre-and post-spinal anesthesia periods in cesarean section cases in the sitting position.
- Trial name
- NCT04195087
- Testing
- Masimo Radical-7® Pulse CO-Oximeter®
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Antalya Training and Research Hospital
Hypotension
Intraopertive Hypotension and Postoperative Cardiovascular Complications Among Chinese Elderly Patients Undergoing Oncardiac Surgery : a Retrospective Cohort Study
To explore the relationship of intraoperative hypotension and perioperative cardiovascular complications in elderly noncardiac surgical patients
- Trial name
- NCT06017206
- Volunteers
- 35,262 people
- Sponsor
- Hao Li
Maternal Hypotension After Spinal Anesthesia
Height Versus Height and Weight Based Spinal Bupivacaine on Maternal Haemodynamics for Elective Cesarean in Short Stature Patients
Doses of intrathecal bupivacaine based on patients either height or height and weight has shown to lower the risk of maternal hypotension with similar quality of anesthesia compared to conventional doses.
- Trial name
- NCT04082676
- Testing
- Hyperbaric bupivacaine spinal
- Where
- Nepal
- Volunteers
- 112 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Post Spinal Anaesthesia Hypotension
This is a Study That Aims to Estimate the Effect of Maternal Body Mass Index on the Prophylactic Dose of Norepinephrine Infusion for Preventing Hypotension in Parturient After Spinal Anesthesia
This is a randomized, double-blinded controlled study that aims to estimate the effect of maternal body mass index on the prophylactic dose of norepinephrine infusion for preventing hypotension in parturient after spinal…
- Trial name
- NCT07706426
- Testing
- Nor-epinephrine, Normal Saline
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Hypotension
Reduction in Spinal-induced Hypotension With Ondansetron in Parturients Undergoing Caesarean Section
Subarachnoid block is the preferred method of anaesthesia for caesarean section, but is associated with hypotension and bradycardia, which may be deleterious to both parturient and baby.
- Trial name
- NCT02913768
- Testing
- Ondansetron, Normal saline
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Assiut University
Orthostatic Hypotension, Orthostatic Intolerance
Orthostatic Intolerance and Hypotension After Administration of Morphine in Patients Prior to Hip or Knee Arthroplasty
Incidence of orthostatic intolerance and orthostatic hypotension after intravenous administration of morphine in patients prior to hip or knee arthroplasty.
- Trial name
- NCT04902222
- Testing
- Morphine
- Where
- Denmark
- Volunteers
- 26 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Hypotension (MeSH: D007022), Bradycardia
Prophylactic Ondansetron and Maternal Hemodynamics During Spinal Anesthesia for Elective Cesarean Section
Spinal anesthesia is the preferred technique for elective cesarean section, but it is frequently complicated by maternal hypotension and bradycardia.
- Trial name
- NCT07883772
- Testing
- Ondansetron
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Aydin Adnan Menderes University
Secondary Peritonitis, Post-induction Hypotension
Low-dose Norepinephrine Infusion for Prevention of Post-induction Hypotension in Emergency Surgery for Peritonitis
This study tests whether giving a low-dose norepinephrine infusion just before induction of anesthesia can reduce low blood pressure during emergency surgery for peritonitis.
- Trial name
- NCT07529795
- Testing
- Norepinephrine (0.05 μg/kg/min)
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Bach Mai Hospital
Hypotension After Spinal Anesthesia, Hypotension During Cesarean Delivery
Ephedrine Doses to Prevent Maternal Hypotension After Spinal Anesthesia in Cesarean Section
This randomized controlled trial aims to compare the effectiveness of different doses of ephedrine infusion in preventing maternal hypotension following spinal anesthesia in parturients undergoing cesarean sections.
- Trial name
- NCT06668337
- Testing
- Ephedrine
- Where
- Nepal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
IL-2 Induced Hypotension
Evaluation of M40403 for the Prevention of Dose Limiting Toxicities of High Dose IL-2
The clinical use of IL-2 is currently limited by development of dose-dependent hypotension (systolic blood pressure (SBP) < 90 mm Hg).
- Trial name
- NCT00033956
- Testing
- M40403
- Where
- 3 sites in United States
- Volunteers
- 48 people
- Sponsor
- MetaPhore Pharmaceuticals
Intradialytic Hypotension
Effect of Dialysate Cooling Versus Sodium Profiling in Management of Intradialytic Hypotension Among Chronic Hemodialysis Patients
Chronic kidney disease (CKD) is a worldwide public health issue. Dialysis patients have a tenfold greater relative risk of cardiovascular death than the general population.
- Trial name
- NCT06890195
- Testing
- dialysate cooling, standard dialysate temperature
- Volunteers
- 106 people
- Sponsor
- Assiut University
Cesarean Section Complications, Spinal Anesthesia
Three Protocols for Phenylephrine Administration in Cesarean Delivery
The investigators will compare variable infusion of phenylephrine (at a starting rate of 0.75 mcg/Kg/min) with fixed rate (0.75 mcg/Kg/min which will stop of reactive hypertension occurred) and single shot (1.5 mcg/Kg)…
- Trial name
- NCT03302039
- Testing
- Single shot phenylephrine, Fixed infusion phenylephrine., Variable infusion phenylephrine.
- Where
- Egypt
- Volunteers
- 217 people
- Sponsor
- Cairo University
Dialysis Amyloidosis, Hypotension
Studying the Effect of Dialysate Temperature on Toxin Removal and Hypotension
Hemodialysis (HD) is widely used treatment for end stage renal diseases (ESRD) patients. The chief aims of HD are solute and fluid removal.
- Trial name
- NCT02064153
- Testing
- Cool dialysate, Warm dialysate
- Where
- Singapore
- Volunteers
- 14 people
- Sponsor
- National University Hospital, Singapore
Hypotension
Detecting Hypotension By Continuous Non-invasive Arterial Pressure Monitoring
The purpose of this study is to determine whether continuous non-invasive arterial pressure (CNAP) monitoring is beneficial to maintain maternal hemodynamic stability and improve the outcomes of maternal and fetal comparing with…
- Trial name
- NCT02532270
- Testing
- phenylephrine
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Fudan University
Septic Shock, Sepsis
Effects of Dexmedetomidine on Sublingual Microcirculation and Vascular Waterfall Phenomenon in Patients With Septic Shock
This prospective, multicenter, single-arm, open-label interventional pilot study aims to evaluate the short-term physiological effects of intravenous dexmedetomidine on sublingual microcirculation and vascular-waterfall…
- Conditions
- Septic Shock, Sepsis, Critical Illness
- Trial name
- DEX-MICRO (NCT07657715)
- Testing
- Dexmedetomidine Intravenous Infusion
- Where
- 2 sites in China
- Volunteers
- 20 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Postoperative Pain
Sacral Canal Block for Hip Replacement the Efficacy and Safety of Controlled Intraoperative Hypotension
To observe the efficacy and safety of sacral canal block in controlled blood pressure reduction during hip replacement in the elderly, and to provide a better option for controlled blood pressure reduction during clinical hip…
- Trial name
- NCT07064434
- Testing
- Sacral canal block combined with general anesthesia, Simple general anesthesia
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- General Hospital of Ningxia Medical University
Proximal Humeral Fracture
Impact of Regional Anesthesia on Blood Pressure in Humeral Fracture Surgery
This study aims to compare the hemodynamic impact of two anaesthetic strategies : Regional anesthesia versus General anesthesia in proximal humeral fracture surgery.
- Trial name
- ALR_HUMERUS (NCT05153902)
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Montpellier
Symptomatic Orthostatic Hypotension
Clinical Efficacy of Midodrine in Symptomatic Orthostatic Hypotension
To study the effect of midodrine against the symptoms of orthostatic hypotension
- Trial name
- NCT01515865
- Testing
- Midodrine HCl
- Where
- 32 sites in United States, Czechia and 2 more
- Volunteers
- 98 people
- Sponsor
- Shire
Atrial Fibrillation
Release of Acetylcholine From the Ganglionated Plexus During the Thaw Phase of Cryoballon Pulmonary Vein Ablation (GP RESPONSE Study)
Determine whether the presence of acetylcholine in the systemic circulation, correlates with the hypotensive response observed during the thaw phase of cryoballoon ablation.
- Trial name
- NCT03636100
- Testing
- Cryoballoon ablation
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Saint Luke's Health System
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.