Clinical trials: Arterial Hypotension
Rhinoplasty Surgery
Effects of Dexmetomidine and Remifentanil Used for Controlled Hypotension in Septorhinoplasty Surgery on Cardiac Electrophysiology: Prospective Randomized Study
Our aim in this treatment was to reveal the effects of remifentanil and dexmetomidine, which we used to provide controlled hypotension in septorhinoplasty surgery, on cardiac electrophysiology.
- Trial name
- Effects of Dex (NCT06138574)
- Testing
- Dexmedetomidine, Remifentanil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Orthostatic Hypotension
Water and the Gastropressor Response - Tachyphylaxis
We are studying the effects of oral water ingestion in patients with orthostatic hypotension. In this study, we are testing the null hypothesis that the blood pressure increase with oral water ingestion will not be diminished if…
- Trial name
- NCT00580996
- Testing
- water high dose, water tiny dose
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Satish R. Raj
Hemodialysis
Pneumatic Compression Stockings During Hemodialysis
This study aims to determine the effect of pneumatic compression devices (PCDs) on central blood volume in hemodialysis patients.
- Trial name
- NCT01067170
- Testing
- Pneumatic Compression Stockings
- Where
- Canada
- Volunteers
- 51 people
- Sponsor
- University of Calgary
Parkinson Disease (PD), MSA - Multiple System Atrophy
Test-retest Trial With [11C]MODAG-005 in PD or MSA and AMHC - Pilot Phase
This is an open-label, single-center Phase 1 study evaluating the safety, tolerability, and test-retest characteristics of [11C]MODAG-005, an investigational positron emission tomography/computed tomography (PET/CT) radioligand…
- Conditions
- Parkinson Disease (PD), MSA - Multiple System Atrophy, Healthy Adult Participants
- Trial name
- PIOSA (NCT07640542)
- Testing
- [11C]MODAG-005
- Where
- Germany
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- MODAG GmbH
Caesarean Section
The Pleth Variability Index and Hypotension at Caesarean Under Spinal.
During a caesarean section the blood pressure is usually measured every few minutes and it may fall too quickly to be detected in a timely fashion by this intermittent means.
- Trial name
- NCT02285569
- Where
- United Kingdom
- Volunteers
- 17 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Progressive Supranuclear Palsy, Parkinson Disease
Remote Monitoring in Progressive Supranuclear Palsy (PSP)
This is a single-arm, longitudinal, observational study on the use of wearable sensors and digital health technology to measure fall frequency and motor, speech, and cognitive function in patients with PSP over the course of…
- Conditions
- Progressive Supranuclear Palsy, Parkinson Disease, MSA - Multiple System Atrophy
- Trial name
- NCT04753320
- Where
- 2 sites in United States
- Volunteers
- 85 people
- Sponsor
- Massachusetts General Hospital
Postoperative Cognitive Dysfunction (POCD), Controlled Hypotension for Nasal Surgeries
Comparison of Desflurane, Sevoflurane, and Total Intravenous Anesthesia in Ear Surgery Under Controlled Hypotension
This randomized prospective study aimed to compare desflurane, sevoflurane, and total intravenous anesthesia methods in patients undergoing elective ear surgery under controlled hypotension, with a particular focus on…
- Trial name
- POCD-ENT (NCT07792759)
- Testing
- Desflurane, Sevoflurane, Remifentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Perioperative/Postoperative Complications, Postoperative Cognitive Dysfunction
CEReBral AutorEgulation in Non-cardiac SuRgery and Relationship to Postoperative DeliriUm State
The goal of this observational study is to learn the how to determine the mean arterial pressure(MAP) or blood pressure level to be maintained during non-cardiac surgery for optimal brain health in patients above the age of 60…
- Conditions
- Perioperative/Postoperative Complications, Postoperative Cognitive Dysfunction, Postoperative Delirium, EEG With Periodic Abnormalities
- Trial name
- CERBERUS (NCT06133842)
- Testing
- Intra-op EEG and CO data collection
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Intradialytic Hypotension
A Preliminary Randomized Study of Tianjiu (Auto-moxibustion) Effects in Patients With Intradialytic Hypotension
Intradialytic hypotension (IDH) is a most frequent complication of hemodialysis (HD) and may contribute to cardiovascular events and high mortality.
- Trial name
- NCT02210377
- Testing
- Tianjiu
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- Chang Gung Memorial Hospital
Elective Cesarean Section, Maternal Hypotention
Maternal Hypotension During Cesarean Section and Short Term Neonatal Outcome.
About 20-25% of deliveries are by cesarean section. Most are elective with use of regional anesthesia (spinal/epidural). Drop of blood pressure after regional anesthesia is common.
- Trial name
- NCT00330512
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Ephedrine, Intramuscular
Intramuscular Ephedrine in the Prevention of Hypotension in Patients Undergoing Spinal Anesthesia
Subarachnoid anesthesia is an alternative and usually the first choice for many surgical procedures. It is a simple and safe procedure, however it can present complications such as hypotension and bradycardia.
- Conditions
- Ephedrine, Intramuscular, Hypotension, Spinal Anesthesia
- Trial name
- NCT05498857
- Testing
- Intramuscular ephedrine
- Where
- Brazil
- Volunteers
- 202 people
- Sponsor
- Hospital de Base
Delirium
Hypertension and Controlled Hypotension in the Elderly
Comparision of Exposed Factors of Preoperative Hypertension and Intraoperative Controlled Hypotension on Postoperative Delirium in the Elderly under Radical Resection of Head, Neck and Maxillofacial Tumor
- Trial name
- NCT04433416
- Testing
- hypertension
- Where
- China
- Volunteers
- 98 people
- Sponsor
- Zhang Lei
Sepsis, Low Blood Pressure
MID-STEP (MIDodrine for Sepsis Treatment and Early vasoPressor Weaning) Trial
This study is being done to determine if early administration of Midodrine can improve outcomes by maintaining a higher mean blood pressure off of intravenous medications.
- Trial name
- NCT06319248
- Testing
- Midodrine, Standard of Care
- Where
- 5 sites in United States
- Volunteers
- 308 people
- Sponsor
- Mayo Clinic
Intradialytic Hypotension, Hemodialysis-Induced Symptoms
Timing of Intradialytic Exercise and Its Impact on Intradialytic Hypotension
The objective of this study is to compare the rate of low blood pressure events (Intradialytic Hypotension: IDH) when intradialytic exercise is performed in the first half of the hemodialysis (HD) session as compared to that when…
- Trial name
- NCT03504943
- Testing
- Early Intradialytic Exercise, Late Intradialytic Exercise
- Where
- 3 sites in Canada
- Volunteers
- 112 people
- Sponsor
- University of Manitoba
Ultrasound Based IVC IJV
Comparison Of Ultrasound-Based Measures Of Inferior Vena Cava And Internal Jugular Vein For Prediction Of Hypotension During Induction Of General Anesthesia
Hypotension after induction of general anesthesia is a frequent event in routine practice. Even a short period of hypotension may lead to tissue hypoperfusion and predispose to postoperative complications.
- Trial name
- NCT05526625
- Testing
- Ultrasound-based measurements of IVC & IJV.
- Where
- Egypt
- Volunteers
- 133 people
- Sponsor
- Cairo University
Anesthesia
Evaluation of the Corrected Carotid Flow Time and the Inferior Vena Cava Collapsibility Index in Predicting Post-spinal Anesthesia Hypotension in Geriatric Patients
We include patient who will undergo elective surgeries such as orthopedic surgeries as fixator placement, lower extremity debridement, inguinal hernia, Urosurgery as bladder- prostate resection, hysterectomy, fibroid removal…
- Trial name
- NCT05759533
- Testing
- Corrected carotid flow time, IVC diameter
- Where
- Egypt
- Volunteers
- 284 people
- Sponsor
- Fayoum University Hospital
Orthostatic Hypotension, Reflex Syncope
Data Collection - Of Syncope Tilt Table Testing Study
To characterize the impact of orthostatic hypotension (OH) and reflex syncope on signals measured using a wearable cardiac monitor prototype device.
- Trial name
- COST3 (NCT03721393)
- Testing
- Wearable heart monitor
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston Scientific Corporation
Hypotension, Hypotension on Induction
Perfusion Index as a Predictor of Hypotension Following Sub-arachnoid Block Among Patients Undergoing Lower Segment Caesarean Section
C-section is one of the commonly performed surgical procedures. During this surgical procedure the surgeon cuts into uterine cavity through abdominal wall and takes out the baby.
- Conditions
- Hypotension, Hypotension on Induction, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
- Trial name
- NCT06426784
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Muhammad Haroon Anwar
Anesthesia, Hypotension
Anesthetic Advantages of Dexmedetomidine for Hypotensive Anesthesia
The aim of this study was to evaluate the positive anesthetic properties such as reduce intraoperative analgesic requirement, time to extubation and recovery, and early postoperative pain of dexmedetomidine used as a hypotensive…
- Trial name
- NCT02083055
- Testing
- Dexmedetomidine, Nitroglycerin
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Post Induction Hypotension
Effects of Esketamine and Bilateral Lower Limb Elevation on Hemodynamic Stability During Induction of General Anesthesia in Elderly Patients Undergoing Thoracic Surgery
Video-assisted thoracoscopic surgery (VATS) is widely used in thoracic surgery due to small incisions, low stress response, and high patient tolerance.
- Trial name
- NCT07374458
- Testing
- Esketamine, Bilateral Lower Limb Elevation
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
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