Clinical trials: Arterial Hypotension
Obese Individuals, Central Adiposity
Post-exercise Blood Pressure With Inorganic Nitrate
This study is examining whether acute inorganic nitrate supplementation in the form of beetroot juice, paired with an acute bout of exercise, affects blood pressure and what is the magnitude of the difference compared to exercise…
- Trial name
- BEET-DOWN (NCT07869472)
- Testing
- Beetroot Juice - Active + Exercise, Beetroot Juice - Active + No exercise
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Hypovolemia
Effect of Preoperative Fluid Therapy on Post-induction Hypotension
Although preoperative dehydration is a known risk factor for post-induction hypotension, evidence regarding preemptive weight-based fluid therapy remains limited.
- Trial name
- NCT06231472
- Testing
- weight-based fluid therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Mustafa Burgac
Hypertension
Active Video Game and Potential to Cause Post-exercise Hypotension
The aim of this study was to determine the energy demand and the potential to promote reduce blood pressure of an active video game (AVG).
- Trial name
- NCT02924012
- Testing
- video game active, sedentary video game, walking
- Volunteers
- 14 people
- Sponsor
- Federal University of Paraíba
Acute Postthoracotomy Pain, Chronic Postthoracotomy Pain
The Effect of Paravertebral Block Using a Multi-orifice Catheter on Preventing Acute and Chronic Post-thoracotomy Pain
This study aims to evaluate the effect of the paravertebral block using a multi-lumen catheter on the incidence and severity of acute and chronic postthoracotomy pain compared to the thoracic epidural block.
- Conditions
- Acute Postthoracotomy Pain, Chronic Postthoracotomy Pain, Hypotension After Bolus Dose
- Trial name
- NCT01039870
- Testing
- paravertebral block, thoracic epidural analgesia
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Seoul National University Hospital
Septic Shock, Sepsis
VBI-S for the Treatment of Hypotension in Hypovolemic Septic Shock Patients
This study is being conducted to evaluate the safety and effectiveness of VBI-S in elevating the blood pressure of septic shock patients with absolute or relative hypovolemia.
- Conditions
- Septic Shock, Sepsis, Hypovolemia
- Trial name
- NCT04257136
- Testing
- VBI-S
- Where
- 8 sites in United States
- Volunteers
- 20 people
- Sponsor
- Vivacelle Bio
Hypotension
The Effect of Sevoflurane Versus Isoflurane on Vasopressor Need
Aim of this study is to determine the effect of isoflurane versus sevoflurane on blood pressure and systemic vascular resistance.
- Trial name
- ESIVAN (NCT00922844)
- Testing
- Sevoflurane and isoflurane
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- UMC Utrecht
Traumatic Brain Injury
Observational Study of Cortical Spreading Depression in Human Brain Trauma
Since the primary damage from traumatic brain injury (TBI) is irreversible, the focus of medical management of TBI is preventing secondary injury that can be life-threatening and worsen patient outcome.
- Trial name
- COSBID-TBI (NCT00803036)
- Where
- 5 sites in United States, United Kingdom
- Volunteers
- 165 people
- Sponsor
- University of Cincinnati
Ultrasound Guidance
Clinical Study of Combined Carotid Artery With Inferior Vena Cava Ultrasonography to Predict Hypotension After Induction of General Anesthesia
Studies have shown that the clinical application of ultrasound to measure large blood vessels related parameters has been widely used to assess the blood volume status of patients, with the advantages of simple, non-invasive and…
- Trial name
- NCT05472025
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Tongji Hospital
Scoliosis, Spinal Deformity
Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Spinal Deformations
Improving the anesthesiology management for surgical correction of spinal deformations with introducing the diagnostic methods and treatment strategy of acute pain, preventing the evolution of chronic pain.
- Conditions
- Scoliosis, Spinal Deformity, Acute Pain, Chronic Pain
- Trial name
- BBESPB (NCT04697498)
- Testing
- Bilateral bi-level Erector spine plane block, General anaesthesia
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Lviv National Medical University
Fraility, Hypotension
The Effect of Frailty on Hypotension After Anesthesia Induction
Frailty is defined as a state of weakness resulting from a decrease in physiological reserves due to physiological changes, diseases, and/or malnutrition associated with advancing age.
- Trial name
- NCT07351552
- Volunteers
- 80 people
- Sponsor
- Selcuk University
Cerebrovascular Accident
Heart Rate Variability and Orthostatic Hypotension in Stroke Patients Evaluated by Intelligent Biosensor System
This research investigated the heart rate variability (HRV) and stroke patients' orthostatic hypotension in hospitalized stroke patients accompanied with dizziness at varied tilting angle controlled by tilting table with…
- Trial name
- NCT02358252
- Where
- Taiwan
- Sponsor
- Changhua Christian Hospital
Hypotension, Spinal Anesthesia
Midodrine for Prophylaxis Against Post Spinal Hypotension in Elderly Population
Hip fracture is a common and serious healthcare problem which commonly affects elderly populations. The common route of anesthesia for hip arthroplasty is spinal anesthesia.
- Conditions
- Hypotension, Spinal Anesthesia, Elderly
- Trial name
- NCT05548985
- Testing
- Midodrine Oral Tablet, Metoclopramide
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Cairo University
Menkes Disease
NORTHERA (DROXIDOPA) for Dysautonomia in Pediatric Survivors of Menkes Disease
This clinical trial will evaluate the safety, tolerability, dosing, and efficacy of Northera (Droxidopa) in children with Menkes disease aged 7 to 17 years who survived the major neurodegenerative and neurocognitive effects of…
- Trial name
- NCT07398508
- Testing
- Droxidopa Oral Product
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Stephen G. Kaler
Haemodialysis
Potassium in Haemodialysis Fluids and Haemodynamics
In a study published in 1995 in the American Journal of Kidney Diseases, Dolson et al demonstrated that a rapid decrease of serum potassium concentrations during haemodialysis would produce a significant increase in systolic…
- Trial name
- NCT01224314
- Testing
- Changing potassium concentration in dialysis fluids
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- Ospedale Regionale di Locarno
Post Induction Hypotension, Postoperative Morbidity
Preoperative Carotid Doppler Ultrasound Parameters for Prediction of Post-Induction Hypotension in Elective Non-Cardiac Surgery
This prospective observational study aims to evaluate the predictive value of preoperative carotid Doppler ultrasound parameters, including carotid velocity-time integral (carotid VTI) and corrected carotid flow time (ccFT), for…
- Trial name
- NCT07488182
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Necmettin Erbakan University
Adverse Effect
Norepinephrine Prophylaxis for Postspinal Anesthesia Hypotension in Parturients With Preeclampsia.
The purpose of this study is to investigate the suitable infusion dose of norepinephrine for prophylaxis against postspinal anesthesia hypotension in parturients with preeclampsia undergoing cesarean section.
- Trial name
- NCT04556370
- Testing
- Normal saline, Norepinephrine
- Where
- China
- Volunteers
- 180 people
- Sponsor
- General Hospital of Ningxia Medical University
Cesarean Section Complications, Regional Anesthesia Morbidity
Novel Predictors of Post Spinal Hypotension in Cesarean Sections: Evaluating Jugular Vein Collapsibility Index and Shock Indices
Jugular vein collapsibility index and shock indices (Shock index, Modified Shock Index, Diastolic Shock Index) may be useful in estimating post spinal hypotension in cesarean section operations.
- Conditions
- Cesarean Section Complications, Regional Anesthesia Morbidity, Hemodynamic Instability, Shock
- Trial name
- NCT05953129
- Testing
- Right Jugular Vein Collapsibility Index
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Cesarean Section Complications
Norepinephrine Infusion Different Doses in Cesarean Delivery
three doses (0.025 mcg/Kg/min, 0.050 mcg/Kg/min, and 0.075 mcg/Kg/min) of norepinephrine will be compared for prophylaxis against Post-spinal anesthesia hypotension during Cesarean delivery.
- Trial name
- NCT03182088
- Testing
- norepinephrine infusion (0.025 mcg/Kg/min), norepinephrine infusion (0.050 mcg/Kg/min), norepinephrine infusion (0.075 mcg/Kg/min)
- Where
- Egypt
- Volunteers
- 284 people
- Sponsor
- Cairo University
Parkinson Disease, Neurogenic Orthostatic Hypotension
Brain Perfusion & Oxygenation in Parkinson's Disease With NOH
This is a double blind placebo controlled trial in Parkinson's disease (PD) patients with neurogenic orthostatic hypotension (NOH).
- Trial name
- NCT03229174
- Testing
- Droxidopa
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- William Ondo, MD
Spinal Anaesthesia Induced Hypotension
Effect of Ondansetron on the Incidence of Spinal Anaesthesia-Induced Hypotension in Elderly Patients Undergoing Fracture Hip Surgery
This study aims to compare prophylactic intravenous ondansetron 4 mg versus placebo regarding the incidence of spinal anaesthesia-induced hypotension, defined as mean arterial pressure (MAP) fall >20% from baseline or systolic…
- Trial name
- NCT07914868
- Testing
- Ondansetron
- Where
- Egypt
- Volunteers
- 142 people
- Sponsor
- Assiut University
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