Clinical trials: Arterial Line
Surgeries Requiring Arterial Lines
Comparing Palpation Guided and Ultrasound Guided Arterial Line Placement
When surgery is performed under general anesthesia, a catheter is placed in a vein to administer drugs and saline. During major operations, an additional catheter is placed in an artery in order to measure the blood pressure…
- Trial name
- NCT01757314
- Testing
- ultrasound technique, palpation technique
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Rutgers, The State University of New Jersey
Pulmonary Arterial Hypertension
Clinical Study Evaluating the Effects of First-line Oral cOmbination theraPy of maciTentan and tadalafIl in Patients With Newly Diagnosed pulMonary Arterial Hypertension (OPTIMA)
The purpose of the study is to document the effect of first line dual oral combination therapy with macitentan 10mg and tadalafil 40mg on pulmonary vascular resistance (PVR) in treatment-naïve patients with newly diagnosed…
- Trial name
- OPTIMA (NCT02968901)
- Testing
- macitentan, tadalafil
- Where
- 18 sites in France
- Volunteers
- 46 people
- Sponsor
- Actelion
Cholangiocarcinoma
Efficacy and Safety of Hepatic Arterial Infusion Chemotherapy Combined With Tislelizumab and Regorafenib as First-Line Therapy for Advanced Cholangiocarcinoma
The goal of this clinical trial is to evaluate the efficacy and safety of hepatic arterial infusion chemotherapy (HAIC) combined with tislelizumab and regorafenib as first-line therapy in patients with locally advanced or…
- Trial name
- NCT07619937
- Testing
- HAIC Combined with Tislelizumab and Regorafenib
- Where
- China
- Volunteers
- 31 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Arterial Line, Ischemia
Subcutaneous Nitroglycerin to Prevent Radial Artery Occlusion in Children
The primary objective of the study is to evaluate the vasodilative effect of subcutaneous nitroglycerin to prevent radial arterial occlusion(RAO) after removal of the radial arterial catheter in pediatric patients.
- Trial name
- NCT05443061
- Testing
- Nitroglycerin, Normal saline
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Seoul National University Hospital
Hemodynamic Instability
Effect of Extended Infusion Lines on Pulse Contour-based Measurements
Hemodynamic monitoring of the critically-ill patients is increasingly performed using an arterial pulse contour-based cardiac output device such as the proAQT system.
- Trial name
- NCT03599440
- Testing
- Pressure line extensions
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Hepatocellular Carcinoma, Atezolizumab Plus Bevacizumab
Low-Dose Bevacizumab and Atezolizumab Combined With TACE-HAIC in Unresectable Hepatocellular Carcinoma
This is a prospective, single-arm, phase II clinical study designed to evaluate the efficacy and safety of low-dose bevacizumab plus atezolizumab combined with transarterial chemoembolization followed by hepatic arterial infusion…
- Conditions
- Hepatocellular Carcinoma, Atezolizumab Plus Bevacizumab, Transarterial Chemoembolization
- Trial name
- NCT07543510
- Testing
- TACE-HAIC + Atezolizumab + Low-dose Bevacizumab
- Volunteers
- 38 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
General Anesthesia, Blood Pressure
Assessment of Effectiveness of Continuous Non-invasive Haemodynamic Monitor by Compared to Invasive Blood Pressure and Pulse Oximeter Monitoring on Patients Undergoing General Anesthesia Surgeries for More Than 60 Minutes
The goal of this observational study is to assess whether the continuous non-invasive haemodynamic monitor MOH200 (measuring blood pressure as well as pulse rate) is effective or not in people undergoing general anesthetic…
- Conditions
- General Anesthesia, Blood Pressure, Pulse Rate, Arterial Line
- Trial name
- NCT06383000
- Volunteers
- 55 people
- Sponsor
- BLZ Technology (Wuhan) Co.,Ltd
Blood Pressure, Arterial Line
Non Invasive Continuous Blood Pressure Sensor
The primary objective of this study is to collect training data in order to establish a method for correlating arterial blood pressure with voltage output signals from a non-invasive piezoelectric array sensor placed on the skin…
- Conditions
- Blood Pressure, Arterial Line, Anesthesia
- Trial name
- NCT05689294
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Blood Pressure Measurement
Data Collection of Arterial Line Waveform and BP Values
Collect continuous systolic and diastolic blood pressure values and waveforms as recorded by an arterial line catheter and by non-invasive blood pressure (NIBP) and to collect Photoplethysmogram Pulse Oximetry (PPG) waveform in…
- Trial name
- NCT04510753
- Testing
- Arterial catheterization kit, GE Datex-Ohmeda Finger Clip Pulse Oximeter Sensor, NIBP Cuff (GE Healthcare)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Sensifree Ltd.
Coronary Artery Disease, Coronary Artery Stenosis
Healthy Endothelial Accelerated Lining Inhibits Neointimal Growth
This is a multi-center, prospective, non-randomized study. Approximately 90 patients from up to 16 centers will be entered in the study. Patients will be followed clinically for up to 5 years post-procedure.
- Trial name
- NCT00349895
- Testing
- Coronary stent implantation
- Where
- 15 sites in Austria, Belgium and 4 more
- Volunteers
- 100 people
- Sponsor
- OrbusNeich
Carcinoma, Small Cell Lung Cancer
Efficacy and Safety of DEB-BACE Combined With Serplulimab in First-line Treatment of SCLC
This project aims to conduct a prospective, single-center, randomized, open-label, two-arm study to compare the clinical efficacy and safety of bronchial arterial chemoembolization with drug-eluting beads (DEB-BACE) combined with…
- Trial name
- NCT06364046
- Testing
- Drug-eluting beads bronchial arterial chemoembolization, Serplulimab, Intravenous chemotherapy
- Where
- China
- Volunteers
- 56 people
- Sponsor
- The Central Hospital of Lishui City
Renal Failure, Hemodynamics
Hemodynamic Assessment APCO Monitor vs Crit Line for Renal Replacement Rx
Fluid and volume management are a challenging part of critical care and the difficulties increase in the face of renal failure. Utilizing the Crit-Line to monitor blood volume changes in conjunction with arterial pressure cardiac…
- Trial name
- APCOvC-Line (NCT00666003)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Baystate Medical Center
HCC - Hepatocellular Carcinoma
The DoHAICs Study Expansion Phase
We explored the efficacy and safety of the first-line treatment of unresectable hepatocellular carcinoma with donafenib combined with hepatic artery infusion chemotherapy (HAIC) and sintilimab .
- Trial name
- NCT07584018
- Testing
- Donafenib, sintilimab, HAIC
- Volunteers
- 90 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Arterial Line, Consent of Patients
Hemodynamic and Biological Evaluations During Reventilation Collapse in ICU
Prospective, observational clinical multicentric study in ICU; during the period surrounding the orotracheal intubation.
- Conditions
- Arterial Line, Consent of Patients, Adult Patients, Tracheal Intubation in ICU
- Trial name
- REVECOL (NCT01785654)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Clermont-Ferrand
Hepatocellular Carcinoma
HAIC Combined With Second-line "Target Immunity" for HCC With TACE Standard Treatment Low Response or Failure
This study is a prospective, randomized controlled, multicenter clinical study. The purpose of this study is to explore the efficacy and safety of hepatic artery infusion chemotherapy (HAIC) combined with second-line regorafenib…
- Trial name
- NCT05233358
- Testing
- Hepatic Artery Infusion Chemotherapy, Transarterial Chemoembolization, Regorafenib
- Volunteers
- 176 people
- Sponsor
- The Central Hospital of Lishui City
Chronic Kidney Disease Requiring Chronic Dialysis
The Effect of High-flux Hemodialysis and On-line Hemodiafiltration on Endothelial Function.
The main aim of this project is to evaluate, in patients with chronic kidney disease (CKD5D), the role of adhesion molecules in leukocyte adhesion and transendothelial migration involved in atherogenesis.
- Trial name
- NCT03942744
- Testing
- on-line hemodiafiltration
- Where
- 2 sites in Spain
- Volunteers
- 88 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Blood Pressure, Perioperative/Postoperative Complications
SOMNOmedics Clinical Validation Trial
Observational study in which pulse transit time (PTT) as a method and the device to register this data is compared with arterial blood pressure.
- Trial name
- NCT03307889
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Uppsala University
Atherosclerosis, Coronary Disease
Study of the Interaction Between the Cells Lining Blood Vessels and Angiotensin-Converting Enzyme
The walls of blood vessels are lined by flat cells that are responsible for releasing substance(s) that control the activity of the blood vessel. These cells are referred to as the endothelium of the blood vessel.
- Trial name
- NCT00001461
- Where
- United States
- Volunteers
- 209 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Blood Pressure Measurement
Continuous Non-Invasive Blood Pressure System Data Collection in Comparison to Invasive Radial Arterial Pressure
The purpose of this study is to evaluate methods to modify blood pressure in humans and measure the effectiveness of such methods.
- Trial name
- NCT04456179
- Testing
- GE Datex-Ohmeda Oxy-F Finger Clip Pulse Oximeter Sensor, Arrow® arterial catheterization kit (Teleflex)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Sensifree Ltd.
Leukodystrophy, White Matter Disease
LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies
Leukodystrophies, and other heritable disorders of the white matter of the brain, were previously resistant to genetic characterization, largely due to the extreme genetic heterogeneity of molecular causes.
- Conditions
- Leukodystrophy, White Matter Disease, 4H Syndrome, Adrenoleukodystrophy
- Trial name
- NCT02699190
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- Children's Hospital of Philadelphia