Clinical trials: Arterial Occlusive Disease
Accidental Falls, Fall Due to Loss of Equilibrium
OHI--Randomized Control Trial to Evaluate Efficacy, Acceptability, and Perception of Benefit of an Innovative Custom AFO
The investigators propose a randomized control trial to evaluate long term effects and effectiveness of Moore Balance Brace (MBB) ankle foot orthoses (AFO) in reducing risk of falling in older adults.
- Conditions
- Accidental Falls, Fall Due to Loss of Equilibrium, High Risk of Falls Due to Mobility Limitation, Diabetes
- Trial name
- NCT02819011
- Testing
- MBB AFO, Control
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Bijan Najafi, PhD
Other Abnormal Uterine and Vaginal Bleeding
Permanent Occlusion of Uteine Arteies in Management of Abnormal Uterine Bleeding
Prospective observational interventional study , The study done in two phases: 1. Phase one from October 2011to May 2012 pilot study including twenty nine (29) premenopausal patients followed up for six months 2.
- Trial name
- NCT05423067
- Testing
- bilateral permanent occlusion of uterine arteries
- Where
- Egypt
- Volunteers
- 116 people
- Sponsor
- Mansoura Integrated Fertility Center
Coronary Artery Disease
Drug-Eluting Stenting Followed by Cilostazol tREAtment Reduces SErious Adverse Cardiac Events (DECREASE-PCI)
The DECREASE-PCI trial is a prospective, randomized, placebo controlled, double-blind, phase 4 study to evaluate efficacy and safety of triple anti-platelet therapy compared with dual antiplatelet therapy in patients treated with…
- Trial name
- NCT01346865
- Testing
- Cilostazol
- Where
- 12 sites in South Korea
- Volunteers
- 402 people
- Sponsor
- Seung-Jung Park
Stable Chronic Angina, Ischemic Heart Disease
Effect of Remote Intervention in Patients With SCAD
The study was a multicenter, two-arm, parallel, open-label, prospective clinical trial that evaluated a remote intervention with 1 year of follow-up.
- Conditions
- Stable Chronic Angina, Ischemic Heart Disease, Coronary Artery Disease, Heart Diseases
- Trial name
- NCT04795492
- Testing
- remote intervention, Routine outpatient follow-up
- Where
- China
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Chronic Coronary Syndrome, Hypertension
Benidipine in Hypertensive and/or Chronic Coronary Syndrome Patients
Evaluation of the clinical outcomes of Benidipine initiated by physician's preference in patients with hypertension and/or angina pectoris (chronic coronary syndrome) presenting to cardiology outpatient clinics in Türkiye.
- Conditions
- Chronic Coronary Syndrome, Hypertension, Angina Pectoris
- Trial name
- BenidipineTR (NCT06808321)
- Testing
- Benidipine Hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 1,659 people
- Sponsor
- The Society of Prevention and Awareness of Cardiovascular Diseases
Acute Myocardial Infarction, Coronary Artery Disease
Cardiac MRI for Patients Enrolled in INFUSE-AMI
Background: INFUSE AMI is an ongoing clinical trial examining how patients with heart attacks are treated. The study's aim is to help determine the best way to treat patients with specific kinds of heart attacks caused by blood…
- Conditions
- Acute Myocardial Infarction, Coronary Artery Disease, Myocardial Fibrosis, Gadolinium
- Trial name
- NCT01059214
- Where
- United States
- Volunteers
- 455 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Coronary Artery Disease
Evaluation of Inspiratory Muscle Strength Early After Coronary Artery Bypass
The purpose of this study is to evaluate the effects of a 6-day postoperative in hospital cardiopulmonary rehabilitation program on inspiratory muscle strength and its potential association with improved functional capacity after…
- Trial name
- NCT00873028
- Testing
- In Hospital Cardiopulmonary Rehabilitation
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Peripheral Arterial Occlusive Disease
Dose-finding, Safety and Efficacy Study of NV1FGF in Patients With Intermittent Claudication
The primary objective is to assess safety and efficacy of two different doses of NV1FGF as compared to placebo. The secondary objective is to assess the pharmacokinetics of NV1FGF and FGF-1 protein.
- Trial name
- TALISMAN 211 (NCT01157871)
- Testing
- XRP0038 (NV1FGF)
- Where
- 4 sites in United States, Belgium and 2 more
- Volunteers
- 36 people
- Sponsor
- Sanofi
Peripheral Artery Disease, Peripheral Vascular Disease
BARD® Study of LIFESTREAM™ Balloon Expandable Covered Stent Treating Iliac Arterial Occlusive Disease
Collect confirmatory evidence of the safety and effectiveness of the Balloon LIFESTREAM™ Stent Graft for the treatment of stenoses and occlusion in the iliac arteries.
- Conditions
- Peripheral Artery Disease, Peripheral Vascular Disease, Arterial Occlusive Disease
- Trial name
- BOLSTER (NCT02228564)
- Testing
- Percutaneous transluminal angioplasty (PTA), LIFESTREAM™ covered stent
- Where
- 20 sites in United States, Germany and 1 more
- Volunteers
- 155 people
- Sponsor
- C. R. Bard
Coronary Artery Disease, Coronary Artery Disease Progression
Disease Characteristics of R-CAD
The present case-control study is designed to investigate the disease characteristics of rapidly progressive coronary artery disease (R-CAD) by comparing the demographics, clinical features, lab results, imaging findings, and…
- Conditions
- Coronary Artery Disease, Coronary Artery Disease Progression, Coronary Stenosis, Coronary Restenosis
- Trial name
- NCT07239921
- Testing
- Protocol-defined Examinations and Evaluations
- Volunteers
- 52 people
- Sponsor
- Peking Union Medical College Hospital
Peripheral Artery Disease (PAD)
Results of the Treatment of Medium and Long de Novo and Restenotic Lesions in the Superficial Femoral Artery and/or Popliteal Artery With Primary or Salvage Pulsar® -18 t3 Stent
The purpose of this post-authorization registry is to describe the clinical outcomes of de novo and restenotic lesions in the superficial femoral and/or popliteal artery treated with the PULSAR® -18 T3 stent, implanted both…
- Trial name
- T3PROJECT (NCT05665816)
- Testing
- Stent PULSAR® -18 T3,
- Volunteers
- 100 people
- Sponsor
- Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
Heart Failure, Pulmonary Hypertension
Development of Novel Physiological CMR Methods in Health and Disease
Physiological cardiovascular stress test plays a crucial role in the assessment of patients with suspected heart disease. There are several methods of cardiac physiological stress tests and each of them offer varied insight into…
- Conditions
- Heart Failure, Pulmonary Hypertension, Myocardial Infarction, Coronary Artery Disease
- Trial name
- NCT03854071
- Testing
- intravenous fluid challenge
- Where
- United Kingdom
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Ischemic Attack, Transient, Transient Ischemic Attack
Pocket Sized Carotid Stenosis Screening by Junior Doctors
Among patients admitted with cerebral ischemia (stroke and transitory ischemic attack (TIA)) it is important to reveal the underlying cause of the disease.
- Conditions
- Ischemic Attack, Transient, Transient Ischemic Attack, Stroke, Cerebrovascular Accident
- Trial name
- NCT02992821
- Testing
- Bed-side pocket size ultrasound imaging, High frame rate tracking doppler
- Where
- 2 sites in Norway
- Volunteers
- 75 people
- Sponsor
- Helse Nord-Trøndelag HF
Carotid Stenoses
Additional Neurological Symptoms Before Surgery of the Carotid Arteries - A Prospective Study (ANSYSCAP)
A single center observational study. Observing the time between cerebrovascular symptoms and Carotid Endarterectomy (CEA) and patient outcome.
- Trial name
- ANSYSCAP (NCT00514592)
- Testing
- New Guidelines
- Where
- Sweden
- Volunteers
- 230 people
- Sponsor
- Umeå University
Peripheral Arterial Disease
A Study of the Gore VIABAHN BX for Treatment of Occlusive Disease in the Iliac Arteries.
Evaluation of the Gore(R) VIABAHN BX for the treatment of arterial occlusive disease in the common and/or external iliac arteries.
- Trial name
- VBXFLEX (NCT02080871)
- Testing
- Stenting of the Common and/or External Iliac Arteries
- Where
- 27 sites in United States, New Zealand
- Volunteers
- 134 people
- Sponsor
- W.L.Gore & Associates
Peripheral Artery Disease
Implementation of Vascular Care Team to Improve Medical Management of PAD Patients
This study intends to evaluate the efficacy of a multidisciplinary vascular care team utilizing an intensive guideline-based lipid reduction program in improving risk factor modification as measured by LDL-C reduction at 12…
- Trial name
- NCT04400409
- Testing
- Intervention A - Vascular Care + site 6MWT administration, Intervention B - Standard Care + site 6MWT administration, Intervention A - Vascular Care + CPC EQuIP 6MWT administration
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- Colorado Prevention Center
Coronary Artery Disease With Myocardial Infarction
Resistance Training Added to Aerobic Interval Training to Improve Aerobic Capacity and Muscle Mass in Women With Coronary Artery Disease
The goal of this clinical trial is to find out whether partly replacing aerobic interval training (AIT) with resistance training (RT) leads to greater improvements in physical fitness and muscle mass in women with coronary artery…
- Trial name
- VAKAR (NCT07354399)
- Testing
- Aerobic Interval Training, Traditional Resistance Training, Prolonged Eccentric Phase Resistance Training
- Where
- Slovenia
- Volunteers
- 50 people
- Sponsor
- University Medical Centre Ljubljana
Hyperlipidemia, Hypercholesterolemia
Patient and Provider Assessment of Lipid Management Registry
The purpose of the Patient and Provider Assessment of Lipid Management Registry (PALM) is to gain a better understanding of physicians' cholesterol medication prescribing practices, patient and physician attitudes and beliefs…
- Conditions
- Hyperlipidemia, Hypercholesterolemia, Cardiovascular Disease, Diabetes
- Trial name
- PALM (NCT02341664)
- Where
- 14 sites in United States
- Volunteers
- 7,658 people
- Sponsor
- Duke University
CORONARY ARTERY DISEASE
Multisensor Array for the Localisation of Coronary Artery Stenosis (MALCAS)
This is a proof of concept study involving a novel medical device, developed to investigate the potential for detecting and localising coronary artery stenosis.
- Trial name
- MALCAS (NCT04647448)
- Testing
- Application of sensor patch
- Volunteers
- healthy volunteers welcome
- Sponsor
- Barts & The London NHS Trust
Chest Pain
Validation of the Siemens System Somatom Definition and Operating Software for Cardiac CT Studies
We are evaluating a new computer software package to help us acquire and interpret heart CT studies, which is the purpose of this research project.
- Trial name
- SOMARIS (NCT00481468)
- Where
- United States
- Volunteers
- 385 people, healthy volunteers welcome
- Sponsor
- Corewell Health East
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