Clinical trials: Arterial Occlusive Disease
Carotid Stenosis, Postoperative Cognitive Dysfunction
Neurocognitive Function After Carotid Thrombendarterectomy
Previous studies did not reach a consensus on the influence of the type of anesthesiologic procedure and monitoring, during carotid thrombendarterectomy, on perioperative complications and cognitive outcomes.
- Conditions
- Carotid Stenosis, Postoperative Cognitive Dysfunction, Neurological Impairment
- Trial name
- NCT05739357
- Testing
- NIRS, EEG
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- Clinical Hospital Centre Zagreb
Coronary Artery Disease
Non-invasive Fractional Flow Reserve CT (FFRCT)Scan for the Study of Coronary Vaso-motion
Coronary artery disease (CAD) is a very common cause of heart failure affecting millions of people worldwide, which is caused by build-up of plaque inside arteries of the heart.
- Trial name
- NCT02809157
- Volunteers
- 10 people
- Sponsor
- National Heart Centre Singapore
Peripheral Arterial Disease
Study of NMB Drug Ejecting Balloon for Peripheral Arteries
The purpose of this study is to demonstrate the Safety and effectiveness of the use of NMB's drug ejecting balloon for the treatment of de novo and restenotic lesions in peripheral arterial disease.
- Trial name
- NCT01646801
- Testing
- NMB Balloon Catheter
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- N.M.B. Medical Applications Ltd
Coronary Artery Disease
CCTA to Optimize the Diagnostic Yield of Invasive Angiography
This study aims to reduce patient risk and costs to the healthcare system by improving the diagnostic yield of invasive coronary angiography through existing triage processes to improve risk stratification using Coronary Computed…
- Trial name
- CarDIA (NCT03554057)
- Testing
- Coronary Computed Tomographic Angiography
- Where
- Canada
- Volunteers
- 186 people
- Sponsor
- Hamilton Health Sciences Corporation
Coronary Artery Disease
Evaluation of Effectiveness and Safety of Ultimaster™ Tansei™ Stent and/or Ultimaster Nagomi™ Stent in Routine Clinical Practice
This study is to evaluate the effectiveness and safety of Ultimaster Tansei stent and/or Ultimaster Nagomi stent in the "real-world" daily practice.
- Trial name
- IRIS Tansei (NCT04443530)
- Testing
- Ultimaster™ Tansei™ stent and/or Ultimaster Nagomi™ stent
- Where
- 11 sites in South Korea
- Volunteers
- 2,000 people
- Sponsor
- Duk-Woo Park, MD
Coronary Disease, Coronary Artery Disease
XIENCE V® Everolimus Eluting Coronary Stent System India Post-marketing Single-arm Study
XIENCE V® India is a prospective, open-label, multi-center, observational, single-arm study to evaluate XIENCE V® EECSS continued safety and effectiveness during commercial use in real world settings.
- Conditions
- Coronary Disease, Coronary Artery Disease, Coronary Restenosis
- Trial name
- XIENCE V India (NCT00631228)
- Testing
- XIENCE V® Everolimus Eluting Coronary Stent
- Where
- 18 sites in India
- Volunteers
- 1,000 people
- Sponsor
- Abbott Medical Devices
Coronary Artery Disease
Polymorphisms in CD36 and STAT3 Genes and Different Dietary Interventions Among Patients With Coronary Artery Disease
Background: Cardiovascular diseases are the major health problem worldwide and the understanding of genetic contributions on the development of cardiovascular diseases is increasing significantly.
- Trial name
- GENUTRI (NCT02202265)
- Testing
- Olive oil, Nuts, Control diet
- Where
- Brazil
- Volunteers
- 204 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
Coronary Artery Disease, Atherosclerosis
Balloon Inflation and Plaque Morphology in Revascularisation (BURST)
This study will look at the effects of standardised balloon inflation times, pressure and balloon types and atherosclerotic plaque morphology on the procedural results of percutaneous coronary intervention (PCI).
- Trial name
- BURST (NCT03538067)
- Testing
- Percutaneous coronary intervention (PCI)
- Volunteers
- 30 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Peripheral Arterial Disease
Hypoxic Exercise in Lower Extremity Artery Disease
The aim of this randomized controlled trial is to: Phase I: To explore, in a first pilot phase, the adequate combination of hypoxia severity and exercise intensity in patients with symptomatic lower extremity artery disease…
- Trial name
- NCT03506607
- Testing
- Exercise in hypoxia 1500m, Exercise in hypoxia 2500m, Exercise in normoxia
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Coronary Artery Disease
PITT PCI Xience Registry
Stents are devices utilized to treat cholesterol blockages of the coronary (heart) arteries. The introduction of drug-eluting (coated) stents into clinical practice is regarded as a revolutionary breaktrhough, as it has reduced…
- Trial name
- NCT01299207
- Where
- United States
- Volunteers
- 2,506 people
- Sponsor
- University of Pittsburgh
CMV
Effect of Atorvastatin on Subclinical Atherosclerosis
Statin administration is supposed to reduce subclinical atherosclerosis by decreasing LDL cholesterol levels, possibly via lipid-independent anti-inflammatory effect.
- Trial name
- NCT04101136
- Where
- Indonesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
Coronary Artery Disease, Atheromatosis
Prognostic Indices of Atheromatosis Severity and Coronary Artery Bypass Surgery Outcomes for Patients With Coronary Artery Disease
Coronary artery disease is a multifactorial disease. Traditional risk factors, such as obesity, diabetes, hypertension, stimulate the onset of an inflammatory process in the prone vessel and perivascular adipose tissue, which has…
- Trial name
- NCT06242171
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- Onassis Cardiac Surgery Centre
Dementia, Alzheimer Disease
Efficacy Study of Kinto Care Coaching for Dementia Family Caregivers
The goal of this clinical trial is to evaluate Kinto's Care Coaching intervention for dementia caregivers. The main questions it aims to answer are: Does the intervention help caregivers to address their general caregiving goals…
- Conditions
- Dementia, Alzheimer Disease, Lewy Body Disease, Vascular Dementia
- Trial name
- NCT05916664
- Testing
- Kinto Care Coaching
- Where
- United States
- Volunteers
- 495 people, healthy volunteers welcome
- Sponsor
- Kinto
Peripheral Artery Disease, Access Site Complication
BIOTRONIK 4French for AMBulatory Peripheral Intervention
BIOTRONIK 4French for AMBulatory peripheral intervention. A multicenter, controlled trial comparing 4French versus 6French femoral access for endovascular treatment of lower-extremity peripheral artery disease in an ambulatory…
- Conditions
- Peripheral Artery Disease, Access Site Complication, Outpatient Treatment
- Trial name
- BIO4AMB (NCT03044002)
- Testing
- Biotronik 4 French Portfolio, 6 French Portfolio
- Where
- 5 sites in Austria, Belgium and 2 more
- Volunteers
- 821 people
- Sponsor
- Biotronik AG
Coronary Artery Disease
Coronary Artery Disease (CAD) in Women Marathon Runners
The aim of this study is to determine the effects of extreme fitness in women. The incidence of coronary artery disease observed via multislice computed tomography (MSCT) angiogram will be compared with age and risk-matched…
- Trial name
- NCT00918372
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Minneapolis Heart Institute Foundation
Acute Ischemic Stroke, Intracranial Artery Occlusion
Intra-arterial TNK Following Endovascular Thrombectomy in Patients With Large Vessel Occlusion of Posterior Circulation
Rationale: Recently, one prospective multicenter RCT reported a potential beneficial effect of intra-arterial alteplase following successful endovascular thrombectomy (EVT) in patients with an acute intracranial large vessel…
- Conditions
- Acute Ischemic Stroke, Intracranial Artery Occlusion, Endovascular Thrombectomy
- Trial name
- NCT05684172
- Testing
- Tenecteplase, endovascular thrombectomy alone
- Where
- China
- Volunteers
- 208 people
- Sponsor
- The First Affiliated Hospital of University of Science and Technology of China
Complication of Treatment
Transbrachial Access for Interventions in Patients With Peripheral Arterial Occlusive Disease
The aim of the present study is an evaluation, whether an immobilization of the upper extremity by means of a positioning splint can help to reduce the incidence of local complications after transbrachial puncture for peripheral…
- Trial name
- TBA (NCT05892367)
- Testing
- Transbrachial Access for Interventions
- Where
- Austria
- Volunteers
- 95 people
- Sponsor
- Wilhelminenspital Vienna
Ischemic Stroke, Atrial Fibrillation
Atrial Fibrillation and Carotid Atherosclerosis in Ischemic Stroke Patients-(AFCAS)
The main aim of the study is to investigate the prevalence and characteristics of ischemic stroke patients with atrial fibrillation and concurrent carotid atherosclerosis.
- Conditions
- Ischemic Stroke, Atrial Fibrillation, Carotid Stenosis
- Trial name
- AFCAS (NCT04821700)
- Testing
- Carotid Stenosis
- Where
- Greece
- Volunteers
- 3,000 people
- Sponsor
- University of Thessaly
Stroke, Ischemic, Genetic Disease
CUHK Stroke Biobank
The purpose of the study are: 1. To make quality, characterized samples and related data available for future studies, including Genome Wide Association Studies (GWAS), genomics, and biomarker research; 2.
- Conditions
- Stroke, Ischemic, Genetic Disease, Atherosclerosis, Cerebral
- Trial name
- NCT03291392
- Testing
- Gene expression or biomarkers exploration
- Where
- Hong Kong
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Stroke, Ischemic
Triage of Patients Presenting Beyond 24 Hours With Ischemic Stroke Due to Vertebrobasilar Artery Occlusion
Endovascular thrombectomy (EVT) for posterior circulation occlusion is generally performed within a window of less than 24 hours from the time the patient was last known well (LKW).
- Trial name
- VBAO-LATE (NCT06510634)
- Testing
- Endovascular Therapy
- Where
- China
- Volunteers
- 236 people
- Sponsor
- Tianjin Huanhu Hospital
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