Clinical trials: Arterial Occlusive Disease
Coronary Artery Disease, Heart Disease
Biorepository: Indiana Health Study
Blood samples and health information (e.g., age at diagnosis, test results) are collected for the purposes of genetic research. The blood samples are assigned a number and stored in a repository for safe keeping until they are…
- Conditions
- Coronary Artery Disease, Heart Disease, Healthy
- Trial name
- IHS (NCT00741416)
- Where
- 14 sites in United States
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Fairbanks Institute
Type 2 Diabetes Mellitus
A 2 Year Trial of Patients With Type 2 Diabetes Focusing on Cardiovascular Diagnostics and Metabolic Control
The purposes of this study are: to investigate the extent of cardiovascular complications in a representative cohort (n=135) of adult patients with type 2 diabetes; to examine if modern non-invasive assessment can replace…
- Trial name
- NCT00133718
- Testing
- Combined lifestyle intervention and optimisation of pharmacological treatment
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Asker & Baerum Hospital
Coronary Artery Disease (CAD), Ischemic Heart Disease
ANGIOLITE PMCF Study ( rEPIC04F )
Multicenter, prospective, non-randomized, post-market clinical follow-up (PMCF) study to confirm and support the clinical safety and performance of Angiolite sirolimus eluting stent to meet EU Medical Device regulation (MDR)…
- Trial name
- rEPIC04F (NCT05292014)
- Testing
- ANGIOLITE
- Where
- 6 sites in Spain
- Volunteers
- 81 people
- Sponsor
- Fundación EPIC
Atherosclerosis of Arteries of the Extremities, Unspecified
Beneficial Effects of Grape Seed Proanthocyanidin Extrat on Progression of Atherosclerotic Plaques in Clinical Use
The purpose of this study is to investigate the antiatherogenic effect of GSPE in clinical use
- Trial name
- GSPE (NCT01707615)
- Testing
- GSPE, lifestyle intervention
- Volunteers
- 287 people
- Sponsor
- Jie Qiu
Coronary Artery Disease
Effects of Conditioning Exercises and Resistance Interval Training on Post CABG Patients.
Coronary artery disease (CAD) is a global health challenge influenced by diabetes, hypertension, and psychosocial stress, with women having a higher prevalence of Coronary microvascular disease.
- Trial name
- NCT06844591
- Testing
- Conditioning Exercises/ Aerobic Interval Training, Resistance Interval Training
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Ischaemic Heart Disease
Outcomes of Drug Coated Balloon Angioplasty, A UK Real Life Experience From 2009 to 2015
This is a single center, retrospective, observational cohort study to assess the safety and efficacy of drug coated balloon (DCB) angioplasty in all forms of coronary artery disease.
- Trial name
- DCBNORWICH (NCT03603210)
- Testing
- Drug coated balloon angioplasty
- Where
- United Kingdom
- Volunteers
- 1,000 people
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Coronary Artery Disease
Comparison Between Right and Left Radial Approach in Patients Undergoing Percutaneous Coronary Procedures
Our aim is to compare between right and left radial approach in patients undergoing percutaneous coronary procedures regarding feasibility and complications.
- Trial name
- NCT05626660
- Testing
- Coronary angiography and percutaneous coronary intervention
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Atherosclerosis, Coronary, Coronary Stenosis
Evaluation of Effectiveness and Safety of Rotational Atherectomy in Routine Clinical Practice
This study evaluates the effectiveness and safety rotational atherectomy in routine clinical practice.
- Trial name
- IRIS-ROTA (NCT03427996)
- Testing
- Rotational atherectomy
- Where
- 8 sites in South Korea
- Volunteers
- 500 people
- Sponsor
- Seung-Jung Park
Coronary Artery Disease
Safety and Efficacy of Rotational Atherectomy (RA) in Coronary Dissection
This study is aimed at examining the safety and efficacy of rotational atherectomy (RA) in nondilatable calcified lesion complicated by coronary dissection during percutaneous coronary intervention (PCI) procedure.
- Trial name
- NCT01701596
- Testing
- Immediate rotational atherectomy (RA), Delayed rotational atherectomy (RA)
- Where
- China
- Volunteers
- 198 people
- Sponsor
- Xijing Hospital
Coronary Artery Disease
Korean Multicenter Randomized Controlled Trial (RCT) of Pidogul for Patients With Coronary Stenting
The aim of the current study is to compare the antiplatelet efficacy and safety of clopidogrel napadisilate and clopidogrel bisulfate in Coronary Artery Disease (CAD) patients after coronary stent implantation.
- Trial name
- NCT01584791
- Testing
- clopidogrel napadisilate + aspirin, clopidogrel bisulfate + aspirin
- Where
- South Korea
- Volunteers
- 148 people
- Sponsor
- Seoul National University Hospital
Coronary Disease, Coronary Artery Disease
SPIRIT II: A Clinical Evaluation of the XIENCE V® Everolimus Eluting Coronary Stent System
Prospective, randomized, active-control, single blind, parallel two-arm multi-center clinical trial comparing XIENCE V® Everolimus Eluting Coronary Stent System to the approved commercially available active control TAXUS™…
- Conditions
- Coronary Disease, Coronary Artery Disease, Coronary Restenosis
- Trial name
- SPIRIT II (NCT00180310)
- Testing
- XIENCE V® Everolimus Eluting Coronary Stent, TAXUS™ EXPRESS2™ Paclitaxel Eluting Coronary Stent
- Where
- 32 sites in Austria, Belgium and 11 more
- Volunteers
- 300 people
- Sponsor
- Abbott Medical Devices
Cardiovascular Disease
Dose-dependent Effects of Second-hand Smoke on Vascular Function
The purpose of this study is to determine the vascular effects of brief second-hand smoke exposure on normal healthy individuals.
- Trial name
- NCT01007760
- Testing
- Respirable suspended particles (RSP) PM 2.5 dose of second-hand smoke
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Coronary Artery Disease, Myocardial Ischemia
BIOFLOW-III All-comers Orsiro Safety and Performance Registry
This registry is a clinical post-market evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES).
- Trial name
- BIOFLOW-III (NCT01553526)
- Where
- 43 sites in Austria, Chile and 11 more
- Volunteers
- 1,356 people
- Sponsor
- Biotronik AG
Coronary Artery Disease, Chronic Obstructive Pulmonary Disease
ComparisoN of ticAgrelor vs. Clopidogrel in endoTHeliAl Function of COPD patieNts
This is an investigator-initiated, prospective, single-centre, randomised, phase II, open-label study, testing the superiority of ticagrelor, as compared to clopidogrel, in modulating on-P2Y12 treatment platelet reactivity…
- Trial name
- NATHAN-NEVER (NCT02519608)
- Testing
- Aspirin 100 mg, Ticagrelor, Clopidogrel
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- University Hospital of Ferrara
Peripheral Arterial Disease, Silent Atherosclerosis
Mechanistic Study of Anti-Platelet Therapy in Atherosclerosis
Many people have a higher chance of getting heart problems. These individuals include people who are very overweight (obesity), have high blood pressure (hypertension), diabetes, or other health concerns.
- Trial name
- MPA (NCT07169513)
- Testing
- Aspirin 75 mg daily, Clopidogrel 75 mg daily, Clopidgrel 75 mg daily
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Stroke
The Prehospital Selection of Acute Stroke Patients
The aim of this study is to develop and validate a simple prehospital stroke scale, which would predict the presence of large vessel occlusion (LVO) in patients with acute stroke.
- Trial name
- NCT03072524
- Testing
- FAST PLUS test
- Where
- 4 sites in Czechia
- Volunteers
- 400 people
- Sponsor
- University Hospital Ostrava
Arterial Occlusive Diseases
The Study to Treat Superficial Femoral Artery Occlusions.
The main objective of this study is to assess the performance of the Cordis SMART™ nitinol self-expandable stent for the treatment of superficial femoral artery (SFA) occlusions in comparison with balloon angioplasty only as…
- Trial name
- SUPER UK (NCT00232843)
- Testing
- stent, angioplasty
- Where
- 2 sites in United Kingdom
- Volunteers
- 150 people
- Sponsor
- Cordis US Corp.
Thoracic Aortic Dissection, Thoracic Aortic Aneurysm (true Aneurysm)
Quick Yielding Modified Short-Distance Fenestration Technique for the Treatment of Complex Aortic Arch Diseases: a Multicenter Single-Arm Objective Performance Criteria Trial(QYM-Tech Study)
Background: This study investigates the safety and efficacy of a novel surgical approach combining thoracic endovascular aortic repair (TEVAR) and in situ fenestration reconstruction of supra-aortic branches using the Quick…
- Conditions
- Thoracic Aortic Dissection, Thoracic Aortic Aneurysm (true Aneurysm), Thoracic Pseudoaneurysm, Penetrating Aortic Ulcer
- Trial name
- NCT06639243
- Testing
- QYM Technique
- Where
- China
- Volunteers
- 87 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
ICAD - Intracranial Atherosclerotic Disease
Colchicine Use in Intracranial Atherosclerotic Disease
Intracranial atherosclerotic disease (ICAD) is a major ischaemic stroke aetiology in Asia. Influenced by genetics, lifestyle and metabolic risk factors.
- Trial name
- NCT05503225
- Testing
- Colchicine 0.5 MG
- Where
- Hong Kong
- Volunteers
- 72 people
- Sponsor
- Chinese University of Hong Kong
Coronary Artery Disease
CHoice of Optimal Anti-Thrombotic Strategy in Patients Undergoing Implantation of Coronary Drug-Eluting Stents 4
This study is multi-center, open label, two-by-two factorial, randomized, noninferiority trial to compare the efficacy and safety of polymer-free cobalt-chromium thin drug-coated stents (BioFreedom Ultra) with biodegradable…
- Trial name
- SMART-CHOICE4 (NCT05066789)
- Testing
- Type of stent, Duration of DAPT
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
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