Clinical trials: Arterial Occlusive Diseases
Cardiovascular Diseases, Coronary Artery Disease
ISCHEMIA-Chronic Kidney Disease Trial
The purpose of the ISCHEMIA-CKD trial is to determine the best management strategy for patients with stable ischemic heart disease (SIHD), at least moderate inducible ischemia and advanced chronic kidney disease (CKD; estimated…
- Conditions
- Cardiovascular Diseases, Coronary Artery Disease, Heart Diseases, Myocardial Ischemia
- Trial name
- ISCHEMIA-CKD (NCT01985360)
- Testing
- Cardiac Catheterization, Coronary Artery Bypass Graft Surgery, Percutaneous Coronary Intervention
- Where
- United States
- Volunteers
- 777 people
- Sponsor
- NYU Langone Health
Chest Pain, Coronary Disease
MRI Evaluation of Chest Pain
This study will assess the value of magnetic resonance imaging (MRI) in detecting heart attack and heart attack risk in patients who come to the hospital emergency room because of chest pain.
- Conditions
- Chest Pain, Coronary Disease, Myocardial Infarction
- Trial name
- NCT00001961
- Testing
- MRI
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Coronary Artery Disease, Myocardial Infarction
Outcome After Coronary Artery Bypass Grafting
The E-CABG registry is a multicenter, European registry collecting data on the preoperative characteristics, treatment strategies and outcome of patients undergoing isolated coronary artery bypass grafting (CABG).
- Conditions
- Coronary Artery Disease, Myocardial Infarction, Angina Pectoris
- Trial name
- E-CABG (NCT02319083)
- Testing
- Coronary artery bypass surgery
- Where
- Finland
- Volunteers
- 4,000 people
- Sponsor
- University of Oulu
Coronary Artery Bypass Grafting, Coronary Artery Disease
Radial Artery Assessment in Surgical Coronary Revascularisation
The goal of this observational study is to learn about how screening tests inform the radial artery (RA) suitability for harvesting and coronary bypass grafting in adults with ischaemic heart disease.
- Trial name
- NCT06433960
- Testing
- Modified Allen Test, Pulse-oximetry guided Modified Allen Test, Barbeau Test
- Where
- 2 sites in United Kingdom
- Volunteers
- 77 people
- Sponsor
- Papworth Hospital NHS Foundation Trust
Coronary Artery Disease, Myocardial Ischemia
Comparison of Hyperemic Efficacy Between Central and Peripheral Adenosine Infusion for Fractional Flow Reserve (FFR) Measurement
The purpose of this study is to evaluate the safety and effectiveness of the peripheral IV continuous infusion without the insertion of central venous vascular access method in the achievement of steady-state maximal coronary…
- Trial name
- NCT01070420
- Testing
- FFR via central venous line, FFR via peripheral venous line
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Seoul National University Hospital
Carotid Stenosis
Histological Validation Of Carotid Plaque Composition In Preoperative Imaging
Patients scheduled for carotid endarterectomy undergo preoperative imaging to assess vulnerable plaque. The imaging modalities include (in various combinations at different study sites) 3-dimensional ultrasound, PET/CT imaging…
- Trial name
- NCT01456403
- Testing
- Histological validation
- Where
- 3 sites in Canada
- Volunteers
- 95 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Myocardial Infarction, Coronary Artery Disease
One-Time Complete Revascularization Versus Staged PCI in MVD During Pharmaco-Invasive STEMI Strategy
This study compares two treatment strategies in patients with ST-elevation myocardial infarction (STEMI) and multivessel coronary artery disease (MVD) undergoing a pharmaco-invasive approach after successful fibrinolysis.
- Trial name
- NCT07519590
- Testing
- One-Time Complete Revascularization, Staged Percutaneous Coronary Intervention
- Where
- Egypt
- Volunteers
- 112 people
- Sponsor
- Tanta University
Coronary Artery Disease
Fractional Flow Reserve Versus Angiography for Multivessel Evaluation (FAME) 3 Extended
Coronary artery disease, or narrowing of the blood vessels that provide blood to the heart, is the most common cause of death in the United States and can be treated with either coronary bypass surgery or coronary stent…
- Trial name
- NCT07308860
- Testing
- FFR-guided PCI, CABG
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- Stanford University
Coronary Artery Disease (CAD), Oxidative Stress
Ginger in the Modulation of Inflammatory Cytokines and Oxidative Stress in Patients With Coronary Artery Disease
The study aims to evaluate the effect of ginger supplementation on inflammatory cytokines and markers of oxidative stress in patients with Coronary Artery Disease (CAD).
- Conditions
- Coronary Artery Disease (CAD), Oxidative Stress, Inflammation
- Trial name
- NCT07596979
- Testing
- Ginger
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Universidade Federal Fluminense
Atherosclerosis, Peripheral Artery Disease
Imaging of Totally Blocked Arteries
This study will test how well a new contrast agent (dye) used in magnetic resonance imaging (MRI) can help visualize totally blocked arteries that normally supply blood to the neck, arms or legs.
- Conditions
- Atherosclerosis, Peripheral Artery Disease, Intermittent Claudication, Chronic Total Aterial Occlusion
- Trial name
- NCT00459446
- Testing
- MS-325 Injection (Gadofosveset Trisodium)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Acute Coronary Syndrome, Coronary Artery Disease
Clopidogrel Resistance and Platelet Reactivity in Women Undergoing Percutaneous Coronary Intervention
Plavix (clopidogrel) is a drug that is approved by the FDA (Food and Drug Administration) to reduce the risk of having another heart attack by preventing platelets (blood cells that are important in forming blood clots) from…
- Trial name
- NCT01796873
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- University of Arizona
Coronary Artery Disease
Left Versus Right Radial Artery and Radiation Exposure in Patients With Predictors of Trans-radial Failure
The aim of this study is to measure radiation exposure during coronary angiography (CA) with a trans-radial approach (TRA), specifically comparing access via the left versus right radial artery in patients with suggested clinical…
- Trial name
- NCT01707524
- Testing
- Randomized left versus right radial artery approach
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- NYU Langone Health
Coronary Artery Disease
Long-term Fasting in Patients With a History of PCI
Patients in this prospective cohort study were selected if they had a history of PCI more than 1 year previously. 405 patients were divided based on their preferences to fasting and non fasting and after 1 month of fasting major…
- Trial name
- NCT04772924
- Testing
- fasting, not fasting
- Where
- Iran
- Volunteers
- 405 people
- Sponsor
- Shiraz University of Medical Sciences
Hyperperfusion Syndrome, Moyamoya Disease
Sevoflurane and Hyperperfusion Syndrome
The aim of the present study is to evaluate the effect of sevoflurane postconditioning on the incidence of postoperative hyperperfusion syndrome following revascularization surgery in moyamoya patients.
- Trial name
- NCT02510586
- Testing
- Sevoflurane
- Volunteers
- 152 people
- Sponsor
- Seoul National University Hospital
Coronary Artery Disease, Glucose Intolerance
Exercise Training, Insulin Resistance and Coronary Artery Disease
The purpose of this study was to determine the effects of exercise training on insulin resistance in subjects with coronary artery disease independent of changes in weight, diet, or the effect of an acute bout of exercise.
- Trial name
- NCT00412815
- Testing
- Exercise training
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Peripheral Arterial Disease
Adapted Physical Activity in Patients With Lower Limb Peripheral Arterial Disease
The prevalence of peripheral arterial disease is 12.2% in France. Intermittent claudication is the most common symtom of this disease. During physical exercise, such as walking, blood oxygen (O2) requirements increase.
- Trial name
- ACTIV'AO (NCT04800276)
- Testing
- muscle strengthening targeted on ischemic areas, global muscle strenghtening
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Hospitalier le Mans
Coronary Artery Disease
Aspirin Effectiveness Study
Aspirin is an effective medicine for prevention of heart attacks in patients with coronary artery disease and works by preventing clots from forming.
- Trial name
- NCT01113060
- Where
- Ireland
- Volunteers
- 500 people
- Sponsor
- Royal College of Surgeons, Ireland
Peripheral Artery Diseases
Detour2 Continued Access Study
Prospective, single-arm, multi-center, clinical investigation to continue to evaluate the safety and effectiveness of the PQ Bypass System to access, deliver guidewires, and implant stent grafts for a percutaneous femoropopliteal…
- Trial name
- NCT04625660
- Testing
- PQ Bypass System
- Where
- 3 sites in United States
- Volunteers
- 11 people
- Sponsor
- Endologix
Coronary Artery Disease, Myocardial Infarction
Reduction in Infarct Size by Remote Per-postconditioning in Patients With ST-elevation Myocardial Infarction
Trial objective: To test the hypothesis that remote per-postconditioning in connection with primary PCI will reduce myocardial infarct size patients with STEMI.
- Trial name
- RECOND (NCT02021760)
- Testing
- Primary Percutaneous Coronary Intervention
- Where
- 3 sites in Sweden
- Volunteers
- 120 people
- Sponsor
- John Pernow
Magnetic Resonance Angiography, Peripheral Vascular Diseases
Magnevist (SH L 451A) Intra-individual Dose Comparison Study in Magnetic Resonance Angiography
The objective of the study was to compare the efficacy of Magnevist (SH L 451 A) at doses of 0.1 mmol/kg and 0.2 mmol/kg in contrast-enhanced 3D-Magnetic Resonance Angiography in three regions (abdominal, femoral, and leg…
- Conditions
- Magnetic Resonance Angiography, Peripheral Vascular Diseases, Peripheral Arterial Diseases
- Trial name
- NCT00652418
- Testing
- Gadopentetate dimeglumine (Magnevist, BAY86-4882, SH L 451A)
- Where
- 3 sites in Japan
- Volunteers
- 12 people
- Sponsor
- Bayer
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