Clinical trials: Arterial Stiffness, Blood Pressure
Hypertension
Longitudinal Follow-up Study in Two Chinese Hypertension Cohorts
Essential hypertension is a complex trait that results from interaction between environmental factors and genetic factors. Salt sensitivity is the genetic susceptibility of blood pressure to salt, and it is an intermediate…
- Trial name
- NCT04471389
- Testing
- Incidence and risk factors of hypertension
- Where
- China
- Volunteers
- 5,611 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Living Kidney Donors
A Prospective UK Multicentre Study of Kidney Donors
Studies of patients with established kidney disease, even when this is mild, appear to show that they are at high risk of heart failure, stroke and sudden cardiac death.
- Trial name
- EARNEST (NCT01769924)
- Testing
- Nephrectomy
- Where
- United Kingdom
- Volunteers
- 463 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Hypertension
Endothelin Receptor Function and Acute Stress
Our bodies respond differently to stress. Animal studies by the investigators have found that endothelin-1 plays a role in regulating blood pressure in response to stress.
- Trial name
- End-Stress (NCT02116335)
- Testing
- Bosentan
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Augusta University
Diabetes Mellitus
Blood Pressure and Subclinical Organ Damage
Background: The purpose of this study is to analyze the relationship between central and peripheral blood pressure (clinic and ambulatory) with vascular structure and function, assessed by carotid intima-media thickness (IMT)…
- Trial name
- Vasorisk (NCT01325064)
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Fundacion para la Investigacion y Formacion en Ciencias de la Salud
Blood Flow Restriction (BFR) Training Effects, Arterial Stiffness, Blood Pressure
Effect of Limb Occlusion Pressure Attainment on Cardiovascular, Perceptual, and Performance Responses
To test the effect of limb occlusion pressure attainment in the supine, seated, and standing position on exercise performance, vascular physiology, and muscle.
- Conditions
- Blood Flow Restriction (BFR) Training Effects, Arterial Stiffness, Blood Pressure, Muscle Morphology, Perceptions
- Trial name
- NCT06718582
- Testing
- Delfi Training Device
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Teri Herberger
Hypertension, Cardiovascular Diseases
Improving Blood Pressure and Cardiovascular Risk With Resistance Exercise in African Americans
After the participant meets all inclusion and exclusion criteria, they will be randomized equally to either the Resistance Training group (RT) or Aerobic Training group (AT).
- Conditions
- Hypertension, Cardiovascular Diseases, Vascular Diseases
- Trial name
- BPVR (NCT03016351)
- Testing
- Aerobic Training, Resistance Training
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- University of Illinois Chicago
Hypertension
The COlchicine HypERtENsion Trial
The purpose of this study to investigate the effects of colchicine on measures of vascular and cardiac function in patients with hypertension.
- Trial name
- COHERENT (NCT04916522)
- Testing
- Colchicine
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Herlev and Gentofte Hospital
Adenoma
Arterial Stiffness Index as a Predictor of Surgically Correctable Primary Aldosteronism
Our main objective is to assess whether aortic stiffness is a predictor of blood pressure response after surgery in patients with an aldosterone producing adenoma or a unilateral adrenal hyperplasia.
- Trial name
- NCT01190501
- Testing
- complier device
- Where
- France
- Volunteers
- 96 people
- Sponsor
- University Hospital, Toulouse
Blood Pressure, Arterial Stiffness
Comparison of Different Non-invasive Methods to Assess Pulse Wave Analysis
The primary goal of the study is to compare different methods for pulse wave measurement and analysis which are cuffless and contactless. The novel measurement tools will be compared to cuff-based reference methods.
- Conditions
- Blood Pressure, Arterial Stiffness, Arrythmia
- Trial name
- MULTI-PWA (NCT05790642)
- Testing
- Pulse wave measurement and analysis
- Where
- Germany
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University Medicine Greifswald
Healthy
Acute Vascular Response To Meals Varying In Glycemic Index And Glycemic Load
This study examines the effects of carbohydrate type (high- or low-Glycemic Index (GI)) and amount (high- or low-Glycemic Load (GL)) have on blood glucose levels, blood pressure and arterial stiffness in healthy individuals.
- Trial name
- HILO (NCT01883700)
- Testing
- Boiled Pasta, Boiled Chickpeas with Oil, Instant Mashed Potatoes
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Diabetes
The Effect of Vitamin D Supplementation on Arterial Stiffness in Diabetic Patients
The incidence of type 2 Diabetes Mellitus is increasing at an alarming rate worldwide. Cardiovascular disease is the leading cause of death in patients with type 2 diabetes.
- Trial name
- NCT01500005
- Testing
- Baby D3 drops
- Where
- Israel
- Volunteers
- 74 people
- Sponsor
- Assaf-Harofeh Medical Center
Metabolic Syndrome
Korean Red Ginseng and Metabolic Syndrome
Five factor consisting of Metabolic syndrome is closely linked by insulin resistance. Until now, several studies have been performed about effects of Korea red ginseng on hypertension, diabetes, and hyperlipidemia, but not…
- Trial name
- NCT00976274
- Testing
- Korean red ginseng, starch
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- The Korean Society of Ginseng
Hypertension, Obesity
Bariatric Surgery, Arterial Stiffness and Target Organ Damage Study (BASTOD)
Introduction: Obesity is a major public health problem, associated with many morbidities, including metabolic and cardiovascular disease (CVD).
- Trial name
- BASTOD (NCT01494168)
- Testing
- Bariatric surgery (Roux-en-y bypass or sleeve gastrectomy)
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Montpellier
Hypertension
Dapagliflozin on Blood Pressure Variability and Ambulatory Arterial Stiffness Index in Hypertension
The prevalence of arterial hypertension has remained the same in the last 5 years, however, almost 50% of the population continues without an adequate adjustment according to the National Health Survey of the Midway 2016.
- Trial name
- NCT03592667
- Testing
- Dapagliflozin
- Where
- Mexico
- Volunteers
- 20 people
- Sponsor
- University of Guadalajara
Cardiovascular Risk Factor, Blood Pressure
Comparison of Acute Sauna With Exercise and Sauna
Sauna bathing has been associated with a lower risk for cardiovascular disease (CVD) outcomes, improved vascular endothelial and cardiac function, reduced oxidative stress and lower blood pressure.
- Conditions
- Cardiovascular Risk Factor, Blood Pressure, Arterial Stiffness
- Trial name
- NCT04556422
- Testing
- Aerobic exercise, Sauna bathing
- Where
- Finland
- Volunteers
- 72 people
- Sponsor
- University of Jyvaskyla
Hypertension and Cardiovascular Risk Factors
Knowledge of Vascular Age Contributes to Improve the Collaboration Between Community Pharmacies and Primary Health Care Physicians in Reducing Blood Pressure in Hypertensive Patients.
Cardiovascular diseases are the main cause of death worldwide and elevated blood pressure (BP), called hypertension (HTN), is the principal and most frequent factor for suffering cardiovascular diseases.
- Trial name
- TOGETHER (NCT06761235)
- Testing
- Standard BP intervention, EVA intervention
- Where
- 6 sites in Austria, Portugal and 1 more
- Volunteers
- 1,246 people
- Sponsor
- Enrique Rodilla
End Stage Renal Disease, Hypotension During Dialysis
Effect of Protein Intake During Hemodialysis on Blood Pressure and Arterial Stiffness Indices
Open label, randomized, cross-over clinical study comparing the acute effect of high versus low protein meals during dialysis on intradialytic blood pressure, 24-hour ambulatory blood pressure and arterial stiffness indices on…
- Conditions
- End Stage Renal Disease, Hypotension During Dialysis, Protein Malnutrition, Arterial Sclerosis
- Trial name
- NCT03947710
- Testing
- High-protein meals, Low- protein meals, No meals
- Where
- Greece
- Volunteers
- 45 people
- Sponsor
- Aristotle University Of Thessaloniki
Type 1 Diabetes
Inspiratory Muscle Strength Training in Adults With Type 1 Diabetes
Adults with type 1 diabetes have elevated cardiovascular disease risk, and systolic blood pressure is a leading modifiable contributor to that risk.
- Trial name
- NCT07859943
- Testing
- High-Resistance Inspiratory Muscle Strength Training
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Florida State University
Aging
Role of Flavanols In Cardiovascular Function in Healthy Aging
Groups of naturally occurring compounds called flavonoids are found in foods such as fruits and vegetables, red wine, tea, dark chocolate and cocoa products.
- Trial name
- NCT01395277
- Testing
- High Flavanol first then Low Flavanol, Low Flavanol first then High Flavanol
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Blood Pressure, Racial Disparities
The Influence of Beetroot Juice on Racial Disparities in Vascular Health
Black adults are 30% more likely to die from cardiovascular disease (CVD) compared to White adults, and more than half of this racial disparity in cardiovascular mortality may be attributed to the substantially greater prevalence…
- Conditions
- Blood Pressure, Racial Disparities, Cardiovascular Risk Factor
- Trial name
- NCT05132556
- Testing
- Acute Beetroot Juice
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Georgia Southern University