Clinical trials: Arterial Stiffness
Type 1 Diabetes
Inspiratory Muscle Strength Training in Adults With Type 1 Diabetes
Adults with type 1 diabetes have elevated cardiovascular disease risk, and systolic blood pressure is a leading modifiable contributor to that risk.
- Trial name
- NCT07859943
- Testing
- High-Resistance Inspiratory Muscle Strength Training
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Florida State University
Pulmonary Disease, Chronic Obstructive
A 24-week Arterial Stiffness Study With Fluticasone Furoate/Vilanterol in COPD
The purpose of the study is to investigate the effect of fluticasone furoate/vilanterol Inhalation Powder on arterial stiffness compared with placebo and vilanterol over a 24-week treatment period in subjects with COPD and aortic…
- Trial name
- NCT01336608
- Testing
- Fluticasone Furoate/Vilanterol, Vilanterol
- Where
- 72 sites in United States, Germany and 4 more
- Volunteers
- 446 people
- Sponsor
- GlaxoSmithKline
Diabetes Mellitus
Vascular Markers During OGTT in Diabetics and First-degree Relatives
Arterial stiffness is associated with increased risk for cardiovascular disease. Moreover, the integrity of endothelial glycocalyx plays a vital role in vascular permeability, inflammation and elasticity.
- Trial name
- NCT02244736
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Athens
End-Stage Renal Disease
Comparison of Post-dilution On-line Hemodiafiltration and Hemodialysis
This study aims to compare high-efficiency post-dilution on-line hemodiafiltration and high-flux hemodialysis regarding mortality, hospitalization rate, several clinical and laboratory parameters, and required medications.
- Trial name
- NCT00411177
- Testing
- post-dilution on-line hemodiafiltration, high flux hemodialysis
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 782 people
- Sponsor
- Ercan OK
Aging, Endothelial Dysfunction
Role of Mitochondrial-derived Oxidative Stress to Promote Vascular Endothelial Dysfunction in Non-exercisers With Aging
The primary goal of this intervention is to determine the efficacy of acute mitochondrial-specific antioxidants to improve vascular endothelial function in middle-aged and older (≥45 y) adults who do no perform regular aerobic…
- Conditions
- Aging, Endothelial Dysfunction, Cardiovascular Function, Arterial Stiffness
- Trial name
- NCT05872139
- Testing
- Mitoquinone Mesylate
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Ball State University
Type 2 Diabetes, Hypertension
Step Monitoring to Improve ARTERial Health
Many people with diabetes and/or high blood pressure (hypertension) are not very active. When people are more active, they can reduce the chances of having a heart attack or stroke.
- Trial name
- SMARTER (NCT01475201)
- Testing
- Step count prescription, Usual care
- Where
- 6 sites in Canada
- Volunteers
- 347 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Hypertension
LAAS (Losartan Anti-Atherosclerosis Study)(0954-330)(COMPLETED)
The primary objective of this study is to evaluate efficacy, arterial stiffness measured by Pulse Wave Velocity (PWV) of Losartan potassium group compared to Carvedilol group after 24 weeks of treatment in patients with the…
- Trial name
- NCT00496834
- Testing
- losartan potassium, Comparator: carvedilol, Comparator: losartan (+) hydrochlorothiazide (HCTZ)
- Volunteers
- 201 people
- Sponsor
- Organon and Co
Atrial Fibrillation
Arterial Stiffness and Atrial Fibrillation
Researchers are trying to determine whether arterial stiffness detected by ultrasound can predict outcomes in the development and recurrence of atrial fibrillation.
- Trial name
- NCT04160663
- Testing
- Carotid Ultrasound
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Mayo Clinic
Coronary Artery Disease
Effects of Exercise Training on Endothelial Function, Inflammation, Arterial Stiffness and Autonomic Function in CAD
The main purposes of this study is to analyze, in a randomized controlled trial, the effects of an exercise-based cardiac rehabilitation program (i) on biomarkers of endothelial function, (ii) on biomarkers of inflammation, (iii)…
- Trial name
- NCT01432639
- Testing
- Exercise-based cardiac rehabilitation program
- Where
- Portugal
- Volunteers
- 96 people
- Sponsor
- Universidade do Porto
Arterial Stiffness
Augmented Velocity Index of Intra-abdominal, Carotid and Retinal Arteries
Background: Augmented Velocity Index (Avi) is a new Doppler index which can potentially be used to assess arterial stiffness. The Avi of common carotid artery is found to be associated with arterial stiffness and have initial…
- Trial name
- NCT05273905
- Testing
- Ultrasound derived Avi
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Adenoma
Arterial Stiffness Index as a Predictor of Surgically Correctable Primary Aldosteronism
Our main objective is to assess whether aortic stiffness is a predictor of blood pressure response after surgery in patients with an aldosterone producing adenoma or a unilateral adrenal hyperplasia.
- Trial name
- NCT01190501
- Testing
- complier device
- Where
- France
- Volunteers
- 96 people
- Sponsor
- University Hospital, Toulouse
Arterial Stiffness
Atorvastatin Effects On Arterial Stiffness In Hemodialysis
This research aims to assess effects of atorvastatin on arterial stiffness in hemodialysis patients
- Trial name
- NCT04472637
- Testing
- Atorvastatin
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Alexandria University
Arterial Stiffness
Effect of Interval Training on Arterial Stiffness in Women With Hypertension
this study is aiming to assess the chronic effect of the interval training program on arterial stiffness in women with hypertension
- Trial name
- NCT04862754
- Testing
- interval training exercise
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Large Artery Stiffness, Aortic Disease
Phenotyping Heterogeneity and Regionality of the Aorta
The aorta distributes cardiac stroke volume into the whole body through its finetuned conductance function, that is propagation and modulation of flow pattern.
- Conditions
- Large Artery Stiffness, Aortic Disease, Aortic Stenosis, Aortic Aneurysm
- Trial name
- PHaRAo (NCT05603520)
- Testing
- Collection of Clinical Data
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Infrarenal Abdominal Aortic Aneurysm
Arterial Stiffness, Blood Pressure and Cardiac Output Study
Comparison of non-invasively obtained central blood pressure using SphygmoCor and invasively recorded central blood pressure in patients with an AAA that will be treated with EVAR.
- Trial name
- ABC (NCT03469388)
- Testing
- Pulse wave analyses; central blood presaure parameters
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Rijnstate Hospital
Cardiovascular Risk Factor, Blood Pressure
Diurnal BP Patterns in Those at Increased Risk of CVD
In health, blood pressure (BP) falls at night by >10% compared with day-time values. This natural dipping pattern is important as without it there is an increased risk of cardiovascular disease (CVD).
- Conditions
- Cardiovascular Risk Factor, Blood Pressure, Arterial Stiffness, Chronic Kidney Diseases
- Trial name
- NCT04522765
- Testing
- Assessment of 24 hour blood pressure and arterial stiffness
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Cardiovascular Risk Factor, Cardiovascular Diseases
VOPITB a New Devices to Determine Peripheral Arterial Stiffness: Validation Study
Our group has developed a device called "Velocidad Onda de Pulso Indice Tobillo Brazo (VOPITB)" . In this device the oscillometric method is used for easily and accurately measure the pulse wave velocity PWV in the arms and legs…
- Conditions
- Cardiovascular Risk Factor, Cardiovascular Diseases, Atherosclerosis of Artery
- Trial name
- NCT04303546
- Testing
- arterial stiffness measurements
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Extremadura
Graves' Disease
D-vitamin And Graves' Disease; Morbidity And Relapse Reduction
The purpose of this study is to investigate the effects of vitamin D supplementation on morbidity and risk of relapse in patients with Graves' disease.
- Trial name
- DAGMAR (NCT02384668)
- Testing
- Cholecalciferol
- Where
- 8 sites in Denmark
- Volunteers
- 278 people
- Sponsor
- University of Aarhus
Blood Pressure
Blueberry Consumption Improves Vascular Function and Lowers Blood Pressure in Postmenopausal Women With Pre- and Stage 1-hypertension
Cardiovascular disease (CVD) continues to be the leading cause of death in the U.S. Americans have been more concerned about their blood cholesterol levels and dietary cholesterol intakes rather than their overall cardiovascular…
- Trial name
- NCT01686282
- Testing
- Freeze-dried Blueberry Powder
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Florida State University
Vascular Calcification, Systemic and Arterial Stiffness
Treatment to Reduce Vascular Calcification in Hemodialysis Patients Using Vitamin K
The proposed study will seek to evaluate the prevalence and the progression of vascular calcification in a cohort of maintenance hemodialysis patients in Asian population.
- Conditions
- Vascular Calcification, Systemic and Arterial Stiffness, Complication of Hemodialysis, Deficiency of Vitamin K2
- Trial name
- TReVasc-HDK (NCT02870829)
- Testing
- menaquinone-7
- Where
- Singapore
- Volunteers
- 178 people
- Sponsor
- National University Health System, Singapore