Clinical trials: Arterial Thromboembolic Event
Stroke, Acute, Stroke, Ischemic
Magnetically Enhanced Diffusion for Acute Ischaemic Stroke (MEDIS) Trial
The objective of the MEDIS study is to determine if subjects experiencing an Acute Ischaemic Stroke due to large vessel occlusion, treated with IV tPA combined with the MED procedure have a greater likelihood of recanalisation…
- Conditions
- Stroke, Acute, Stroke, Ischemic, Infarction, Middle Cerebral Artery, Strokes Thrombotic
- Trial name
- MEDIS (NCT03098732)
- Testing
- Magnetically Enhanced Diffusion (MED)
- Where
- 2 sites in United Kingdom
- Volunteers
- 120 people
- Sponsor
- Pulse Therapeutics
Arterial Thromboembolism
A PMCF Study to Confirm the Performance and Safety of the LeMaitre® TufTex Single Lumen Embolectomy Catheter
A post market clinical study to confirm the performance and safety of the LeMaitre® TufTex Single Lumen Embolectomy Catheter on patients undergoing surgical treatment for the removal of arterial emboli and/or thrombi
- Trial name
- SLC (NCT05386277)
- Testing
- TufTex Single Lumen Embolectomy Catheter
- Where
- 3 sites in Belgium, Germany and 1 more
- Volunteers
- 112 people
- Sponsor
- LeMaitre Vascular
Carotid Atherosclerosis, Carotid Stenosis
Carotid Arteries Stenting Complications: Transradial Approach Versus Transfemoral
The aim is to compare the safety of using transfemoral and transradial approach in patient undergoing carotid arteries stenting.
- Conditions
- Carotid Atherosclerosis, Carotid Stenosis, Ischemic Attack, Stroke
- Trial name
- NCT02722720
- Testing
- Transradial carotid artery stenting, Transfemoral carotid artery stenting
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Pulmonary Hypertension, Pulmonary Thromboembolisms
Electrical Impedance Tomography for Assessment of Pulmonary Hypertension
Pulmonary hypertension is a serious and progressive disease that is difficult to treat and diagnose, mainly because its symptoms are nonspecific and often delay recognition. Early diagnosis is a major challenge.
- Trial name
- NCT07453017
- Testing
- Electrical Impedance Tomography (EIT), Right Heart Catheterization
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- University of Sao Paulo General Hospital
Mesenteric Artery Ischemia, Thromboembolism
Endovascular thromBectomy of Acute Mesentery Vessels Occlusion Hybrid With Emergent Laparoscopic Surgery
Acute mesenteric artery thromboembolism(AMT) is one of the important causes of acute abdomen and intestinal necrosis. If the intestinal blood supply is not restore in time, the prognosis of the disease is often poor and even…
- Trial name
- BOWEL (NCT04686981)
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Thromboembolism, Arterial
Fiix-prothrombin Time for Monitoring Warfarin
Experiments suggest that during treatment with vitamin K antagonists (VKA) the activity of coagulation factors (F) II and X better reflect anticoagulation than does FVII.
- Conditions
- Thromboembolism, Arterial, Venous
- Trial name
- Fiix (NCT01565239)
- Testing
- Fiix prothrombin time
- Where
- Iceland
- Volunteers
- 1,156 people
- Sponsor
- Landspitali University Hospital
Aortic Dissection, Thrombosis in Left Atrium and Right Axillary Artery
Multi-detector Computer Tomography Protocol Project: Chest Imaging Technique and Case Presentation
Multi-detector computer tomography protocol project: Chest imaging technique and case presentation.
- Conditions
- Aortic Dissection, Thrombosis in Left Atrium and Right Axillary Artery, Double IVC, May-Thurner Syndrome
- Trial name
- NCT01206751
- Testing
- Chest imaging technique and case presentation
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Medical University WanFang Hospital
Pulmonary Hypertension
PIMR and Pulmonary Vascular Disease
The findings from this innovative, first-in-man, prospective pilot study will elucidate the role of PIMR and RV-IMR in pre-capillary PH.
- Trial name
- NCT05843461
- Testing
- Pulmonary Index of Microcirculatory Resistance, Right Ventricle Index of Microcirculatory Resistance, Pulmonary artery OCT
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, Los Angeles
Stroke
PERIOP 2 - A Safety and Effectiveness of LMWH vs Placebo Bridging Therapy for Patients on Long Term Warfarin Requiring Temporary Interruption of Warfarin.
The purpose of the study is to determine the effectiveness and safety of LMWH postoperative bridging therapy (standard of care) versus postoperative placebo bridging therapy (experimental arm)for patients with mechanical heart…
- Trial name
- NCT00432796
- Testing
- Dalteparin
- Where
- 8 sites in Canada, India
- Volunteers
- 1,473 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Intracranial Embolism, Thrombosis
Ultrasound Enhanced Thrombolytic Therapy of Middle Cerebral Artery Occlusion
The purpose of the present, randomized, controlled multicenter phase III trial is to investigate the safety and efficacy of continuous 1-hour insonation of occluded middle cerebral artery with 2 MHz TCCS in stroke patients…
- Trial name
- NCT00336596
- Testing
- transcranial ultrasound in patients treated with iv t-PA
- Where
- 6 sites in Switzerland
- Volunteers
- 400 people
- Sponsor
- University of Zurich
Carotid Stenosis
Evaluation of the TriActiv ProGuard System During Carotid Artery Stenting
The purpose of this study is to evaluate the safety and efficacy of the TriActiv® ProGuard™ System when used during a stent placement in a blockage within the carotid artery in patients considered to be at high risk for…
- Trial name
- NCT00395785
- Testing
- Carotid Stent Implantation, Embolic Protection
- Where
- 34 sites in United States, Germany
- Volunteers
- 400 people
- Sponsor
- Kensey Nash Corporation
COVID-19
Effect of Anticoagulation Therapy on Clinical Outcomes in COVID-19
Patients with moderate to severe COVID-19 present a very high risk of thromboembolic disease.This multicenter, prospective, randomized, event-driven study evaluates rivaroxaban compared with standard of care with…
- Trial name
- COVID-PREVENT (NCT04416048)
- Testing
- Rivaroxaban, Standard Of Care (SOC)
- Where
- 24 sites in Germany
- Volunteers
- 111 people
- Sponsor
- Charite University, Berlin, Germany
Stroke, Stroke, Acute
Impact of COVID-19 Vaccines on Cerebrovascular Health
Safe and effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines may reduce the transmission of and achieve population immunity against the COVID-19 pandemic, which accounted for more than 3.75million…
- Conditions
- Stroke, Stroke, Acute, Stroke, Ischemic, Dementia
- Trial name
- NCT04992195
- Testing
- Laboratory tests and Montreal Cognitive Assessment
- Where
- Hong Kong
- Volunteers
- 415 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Anesthesia, Pulmonary Hypertension
Effect of Vasopressin Versus Norepinephrine on Post-operative Mean Pulmonary Arterial Pressure Following Pulmonary Endarterectomy Surgery,
Chronic thromboembolic pulmonary hypertension (CTEPH), one of the leading causes of pulmonary hypertension (PH), is caused by the chronic obstruction of the pulmonary arteries following episode of pulmonary embolism.
- Conditions
- Anesthesia, Pulmonary Hypertension, Chronic Pulmonary Thromboembolism, Vasopressor
- Trial name
- VANOPE (NCT07614438)
- Testing
- Vasopressin, Norepinephrine
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Heparin-induced Thrombocytopenia
Rivaroxaban for Treatment of Patients With Suspected or Confirmed Heparin-Induced Thrombocytopenia
Heparin is an anticoagulant (blood thinner) that is commonly used to treat patients with heart attacks and patients with blood clots in their legs or lungs (venous thrombosis).
- Trial name
- NCT01598168
- Testing
- Rivaroxaban
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- McMaster University
Acute Venous and Arterial Thrombotic and Thromboembolic Events, Healthy Volunteers
A Study to Learn How Safe BAY3018250 is, How it Moves Into, Through and Out of the Body, and How it Affects the Body in Healthy Chinese Participants
Researchers are looking for a better way to treat people who have acute venous and arterial thrombotic and thromboembolic events.
- Trial name
- NCT06619483
- Testing
- BAY3018250 Dose 1, BAY3018250 Dose 2
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bayer
Antiphospholipid Syndrome, Venous Thromboembolism
Effectivity and Safety of Different Anticoagulants in Patients With Thromboembolic Antiphospholipid Syndrome
Retrospective monocentric registry to evaluate the efficacy and safety of different anticoagulants in patients with thromboembolic antiphospholipid syndrome
- Conditions
- Antiphospholipid Syndrome, Venous Thromboembolism, Arterial Thromboembolism, Major Bleed
- Trial name
- NCT05195372
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Cardioangiologisches Centrum Bethanien
Coronary Artery Disease, Acute Cerebrovascular Accident
Incidence of Acute Cerebrovascular Events Using Either Minimized or Standard Cardiopulmonary Bypass Circuit
The prospective, randomized, two centre study investigates acute cerebrovascular events during extracorporal circulation and the early post operative outcome when using either the minimized cardiopulmonary bypass circuit…
- Conditions
- Coronary Artery Disease, Acute Cerebrovascular Accident, Intracranial Embolism, Embolism, Air
- Trial name
- ROCsafeTM (NCT00862160)
- Testing
- ROCsafeTM
- Where
- 2 sites in Germany
- Volunteers
- 64 people
- Sponsor
- Hannover Medical School
Carotid Artery Thrombosis, Carotid Artery Stenosis
Randomized Clinical Trial of Polyester vs. Polyurethane Patch for Carotid Endarterectomy
This study examines the risk of thrombogenicity of the carotid patches in polyurethane compared to carotid patches in polyester including death, any stroke, carotid thrombosis at 30 days and long-term results including stroke and…
- Conditions
- Carotid Artery Thrombosis, Carotid Artery Stenosis, Stroke
- Trial name
- NCT02341196
- Testing
- CEA
- Volunteers
- 450 people
- Sponsor
- University of Poitiers
Hematoma
Strategy of Continued Versus Interrupted Novel Oral Anti-coagulant at Time of Device Surgery in Patients With Moderate to High Risk of Arterial Thromboembolic Events
The purpose of this study is to determine the best strategy to manage novel oral anti-coagulants (NOACs) at the time of pacemaker or defibrillator surgery.
- Trial name
- BRUISECONTROL2 (NCT01675076)
- Testing
- Dabigatran, Rivaroxaban, Apixaban
- Where
- 15 sites in Canada, Israel
- Volunteers
- 663 people
- Sponsor
- Ottawa Heart Institute Research Corporation