Clinical trials: Arterial Ulcers
Wound, Venous Leg Ulcer
Geko™ Cross Therapy Registry - Wound
The geko™ Cross Therapy REGISTRY - Wound is a prospective, observational, anonymised data collection Registry with no experimental treatment that will fulfil an unmet need for an observational Registry to provide long-term…
- Conditions
- Wound, Venous Leg Ulcer, Diabetic Foot Ulcer, Arterial Leg Ulcer
- Trial name
- CTR-Wound (NCT05007301)
- Testing
- geko device
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 2,500 people
- Sponsor
- Firstkind Ltd
Diabetic Foot Ulcer, Coronary Artery Disease
Comparison of Imaging Quality Between Spectral Photon Counting Computed Tomography (SPCCT) and Dual Energy Computed Tomography (DECT)
This pilot study wants to determine to which extent SPCCT allows obtaining images with improved quality and diagnostic confidence when compared to standard Dual Energy CT (DECT), both with and without contrast agent injection.
- Conditions
- Diabetic Foot Ulcer, Coronary Artery Disease, Parenchymatous; Pneumonia, Kidney Stone
- Trial name
- SPEQUA (NCT04328181)
- Testing
- Spectral Photon Counting Computed Tomography (SPCCT), DECT (Dual Energy CT)
- Where
- France
- Volunteers
- 339 people
- Sponsor
- Hospices Civils de Lyon
Peripheral Arterial Disease, Peripheral Artery Disease
Implementation of Telemedicine for Patient With Lower Extremity Wounds
The objective of this study is to determine if patients with lower extremity wounds in rural communities who undergo specialty referral through telemedicine have expedited care compared to patients who are treated through…
- Conditions
- Peripheral Arterial Disease, Peripheral Artery Disease, Peripheral Vascular Diseases, Diabetic Foot
- Trial name
- NCT04440839
- Testing
- Telemedicine specialty consultation
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- University of California, Davis
Arterial Insufficiency
Evaluation of a Paraclinical Test for the Diagnosis of Arterial Insufficiency in Diabetic Patients With Foot Ulcers
The number of people living with diabetes has quadrupled worldwide since 1990, and more than 4.5 million people in France have diabetes.
- Trial name
- INFLUX-D (NCT07732270)
- Testing
- Handheld Doppler
- Where
- France
- Volunteers
- 84 people
- Sponsor
- Groupe Hospitalier de la Rochelle Ré Aunis
Peripheral Arterial Disease
Stimulation TcPO2 Test in the PAD Diagnosis in Diabetic Foot
All diagnostic procedures of peripheral arterial disease (PAD) in the diabetic foot (DF) are limited due to diabetes mellitus and its late complications.
- Trial name
- stimTcPO2 (NCT04404699)
- Testing
- Stimulation TcPO2 test
- Where
- Czechia
- Volunteers
- 79 people
- Sponsor
- Institute for Clinical and Experimental Medicine
Diabetic Foot, Arterial Occlusive Disease
Urokinase Therapy in Patients With Diabetic Foot Syndrome
The purpose of this study is to determine whether the additional therapy with low dose urokinase is more effective than only a conventional standard therapy concerning ulcer-healing, rate of major amputation and survival.
- Conditions
- Diabetic Foot, Arterial Occlusive Disease, Ischemia
- Trial name
- NCT00823225
- Testing
- standard therapy, Urokinase
- Where
- 6 sites in Germany
- Volunteers
- 5 people
- Sponsor
- medac GmbH
Peripheral Arterial Disease, Leg Ulcer
Cell Therapy for Lower Limb Ulcers in Patients With Critical Limb Ischemia
Peripheral arterial disease (PAD) can progress to critical limb ischemia (CLI) of the affected lower limb, characterized by pain at rest, ulcerations or gangrene, with a high risk of amputation.
- Trial name
- NCT06326203
- Testing
- CELULAS TRONCO, CONVENTIONAL DRESSING
- Volunteers
- 40 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Acute Aortic Syndrome, Aortic Dissection
18F Sodium Fluoride PET/CT in Acute Aortic Syndrome
The purpose of this study is to determine whether Sodium Fluoride imaging (using Positron Emission Tomography-Computed Tomography - PET-CT) is able to predict disease progression in acute aortic syndrome.
- Conditions
- Acute Aortic Syndrome, Aortic Dissection, Penetrating Aortic Ulcer, Intramural Hematoma
- Trial name
- FAASt (NCT03647566)
- Testing
- 18F Sodium Fluoride Positron Emission Tomography / Computed Tomography, CT Aortic Angiogram, Aortic MRI
- Where
- United Kingdom
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Thoracic Aortic Aneurysm, Penetrating Aortic Ulcers (PAUs)
MBA Early Feasibility Study
The MBA 25-04 study is a prospective, multicenter, non-randomized, single-arm, early feasibility study designed to assess the initial safety of the MBA device through five years following the index endovascular procedure.
- Conditions
- Thoracic Aortic Aneurysm, Penetrating Aortic Ulcers (PAUs), Thoracic Aortic Dissection, Pseudoaneurysm
- Trial name
- NCT07564375
- Testing
- GORE® Multibranch Arch Endoprosthesis, GORE® Ascending Stent Graft
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- W.L.Gore & Associates
Peripheral Arterial Occlusive Disease
Allogeneic ABCB5-positive Stem Cells for Treatment of PAOD
The aim of this clinical trial is to investigate the efficacy (by monitoring the wound size reduction of Peripheral Arterial Occlusive Disease-related clinically relevant ulcers) and safety (by monitoring adverse events) of one…
- Trial name
- NCT03339973
- Testing
- allo-APZ2-PAOD
- Where
- 18 sites in Austria, Czechia and 3 more
- Volunteers
- 24 people
- Sponsor
- RHEACELL GmbH & Co. KG
Arterial Leg Ulcer
Healing of Ischemic Leg Ulcers in Patients Treated With iSONIAzid
The main objective of this trial is to study the healing effect of an oral drug (isoniazid) in patients with ischemic (arterial) leg ulcers defined by a systolic toe pressure <40 mm Hg.
- Trial name
- SONIA (NCT04802928)
- Testing
- Isoniazid 300 milligram
- Where
- Denmark
- Sponsor
- Pharma 2100
Peripheral Arterial Disease
Ultrasound Cavitation Therapy for CLI
In this study, we will explore how ultrasound exposure of ultrasound contrast agents, which produces beneficial shear-mediated bioeffects, can be used to treat patients with severe non-healing ulcers secondary to peripheral…
- Trial name
- NCT05749250
- Testing
- Acoustic cavitation of ultrasound enhancing agents
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Virginia
Critical Limb Ischemia
Bone Marrow Aspirate Concentrate (BMAC) for Treatment of Critical Limb Ischemia (CLI)
Critical Limb Ischemia prevents the legs and feet from receiving oxygen and nutrients needed for proper function. This severe lack of blood flow can lead to painful legs while walking or at rest and can result in foot sores…
- Trial name
- NCT01245335
- Testing
- BMAC injection
- Where
- 34 sites in United States
- Volunteers
- 97 people
- Sponsor
- Harvest Technologies
Abdominal Aortic Aneurysm, Infrarenal Abdominal Aortic Aneurysm
Fast-Track Protocol for Endovascular Aneurysm Repair (EVAR) of Infrarenal Abdominal Aortic Aneurysms
The study aims to evaluate the clinical and economic efficacy of a "Fast-Track" protocol for the elective endovascular treatment (EVAR) of infrarenal abdominal aortic aneurysms (AAA).
- Conditions
- Abdominal Aortic Aneurysm, Infrarenal Abdominal Aortic Aneurysm, Penetrating Aortic Ulcers (PAUs), Iliac Aneurysm
- Trial name
- NCT07431047
- Volunteers
- 50 people
- Sponsor
- University of Bologna
Leg Ulcers Venous, Leg Ulcer Arterial
Local Application of Combined Optical and Magnetic Stimulation (COMS) for Treatment of Chronic Wounds: Safety Evaluation
The demographic shift and the increasing prevalence of chronic wounds represent major challenges for modern health care systems.
- Conditions
- Leg Ulcers Venous, Leg Ulcer Arterial, Leg Ulcer Mixed
- Trial name
- NCT03112395
- Testing
- Pio Medical Device
- Where
- 3 sites in Switzerland
- Volunteers
- 36 people
- Sponsor
- Piomic Medical AG
Diabetes, Diabetic Foot Ulcer
Electrical Stimulation to Accelerate Wound Healing
A clinical study at the Baylor College of Medicine, Division of Vascular Surgery and Endovascular Therapy, is being proposed to test the efficacy of a novel electrical stimulation platform named the Tennant Biomodulator designed…
- Conditions
- Diabetes, Diabetic Foot Ulcer, Peripheral Neuropathy, Peripheral Arterial Disease
- Trial name
- NCT03821675
- Testing
- Electrical Stimulation - Active
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Baylor College of Medicine
Aortic Aneurysm, Penetrating Ulcer
Zenith® TX2® Low Profile TAA Endovascular Graft
The Zenith TX2 Low Profile TAA Endovascular Graft extended study is to collect confirmatory safety and effectiveness data. The Zenith TX2 Low Profile TAA Endovascular Graft is indicated for the treatment of patients with a…
- Conditions
- Aortic Aneurysm, Penetrating Ulcer, Vascular Disease
- Trial name
- NCT02471781
- Testing
- Zenith TX2 Low Profile TAA Endovascular Graft
- Where
- 15 sites in United States
- Sponsor
- Cook Group Incorporated
Vascular Diseases, Peripheral Artery Disease
RECCORD (Recording Courses of Vascular Diseases) Registry
The RECording COurses of vasculaR Diseases registry (RECCORD registry) is an observational, prospective, multicentre, all-comers registry platform.
- Conditions
- Vascular Diseases, Peripheral Artery Disease, Claudication, Critical Limb Ischemia
- Trial name
- RECCORD (NCT03448029)
- Where
- Germany
- Volunteers
- 6,000 people
- Sponsor
- Deutsche Gesellschaft für Angiologie, Gesellschaft für Gefäßmedizin e.V.
Diabetic Foot
Induced Wound Healing by Application of Expanded Bone Marrow Stem Cells in Diabetic Patients With Critical Limb Ischemia
Diabetic foot patients with chronic limb ischemia and without the option for surgical or interventional revascularization were recruited and randomized to the transplant groups or the control group within this clinical trial.
- Trial name
- NCT01065337
- Testing
- tissue repair cells (TRC), bone marrow stem cells (BMC)
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Ruhr University of Bochum
Critical Limb Ischemia
Autologous Adipose-Derived Stromal Cell Delivered Via Intramuscular Injections for the Treatment of Critical Limb Ischemia
This is an open-label, non-randomized, multi center, patient sponsored study of Adipose-Derived Stromal Cell (ASC) implantation via intramuscular injections in patients who have critical limb ischemia not amenable for…
- Trial name
- NCT02099500
- Testing
- Liposuction, Stem Cell Injection
- Where
- United States
- Sponsor
- Ageless Regenerative Institute