Clinical trials: Artery Disease, Peripheral
Peripheral Arterial Disease
Clinical Trial to Evaluate Efficacy and Safety of SID142 in Patients With Chronic Artery Occlusive Disease
Rinexin® Tab (Cilostazol 100mg, Ginkgo biloba leaf extract 80mg) has been widely used as an anti-platelet agent for the treatment of PAD.
- Trial name
- NCT03318276
- Testing
- SID142, Rinexin® Tab
- Where
- South Korea
- Volunteers
- 170 people
- Sponsor
- SK Chemicals Co., Ltd.
Peripheral Artery Disease, Atherosclerosis
Clinical Use and Safety of the Xtreme Touch (Magic Touch PTA)- Neo Sirolimus Coated PTA Balloon Catheter in the Treatment of Infrainguinal Peripheral Arterial Disease
This study postulates that the application of Sirolimus, an anti-proliferative agent that inhibits neointimal hyperplasia, via Sirolimus coated balloon (SCB) will be safe and will result in better arterial patency in…
- Trial name
- XTOSI (NCT04368091)
- Testing
- Xtreme Touch - Neo sirolimus coated PTA balloon catheter
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- Concept Medical Inc.
Chronic Limb Threatening Ischemia, Infrapopliteal Arterial Occlusive Disease
Revascularization of Single Vesrus Multiple Infrapopliteal Vessels in Chronic Limb Threatening Ischemia
This interventional prospective study aims to assess the effectiveness of single vessel versus multiple vessel infrapopliteal angioplasty in patients with chronic threatening limb ischemia .
- Trial name
- NCT07068789
- Testing
- balloon angioplasty
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sohag University
Aortic Aneurysm, Peripheral Arterial Disease
Validation of the Cheetah NICOM by Comparison to TEE During Open Vascular Surgery - Pilot Study
The Cheetah NICOM is a non-invasive cardiac output monitor that has been validated in various clinical contexts but not during the occlusion of major arteries, as takes place in vascular surgery.
- Trial name
- NCT02630550
- Testing
- Cheetah NICOM, Transesophageal echocardiography (TEE)
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Peripheral Arterial Disease, Aortoiliac Occlusive Disease
Predictors of Major Adverse Limb Events After Endovascular Iliac Stenting: a Real-world Cohort Study
Peripheral arterial disease involving the iliac arteries is a common manifestation of systemic atherosclerosis and a major cause of lifestyle-limiting claudication and chronic limb-threatening ischemia.
- Conditions
- Peripheral Arterial Disease, Aortoiliac Occlusive Disease, Chronic Limb-Threatening Ischemia, Intermittent Claudication
- Trial name
- PREMISE-ILIAC (NCT07672249)
- Testing
- Iliac stenting
- Where
- Italy
- Volunteers
- 98 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Critical Lower Limb Ischemia, Postoperative Complications
Impact of Nutritional and Inflammatory Status in Patients With Critical Limb-threatening Ischemia
The peripheral arterial disease (PAD) has been associated with all-cause and cardiovascular mortality. Despite minimally invasive endovascular techniques, patients with critical limb-threatening ischemia (CLTI) have a poor…
- Trial name
- NCT04756115
- Testing
- Vascular Surgery.
- Where
- Spain
- Volunteers
- 310 people
- Sponsor
- Vascular Investigation Network Spanish Society for Angiology and Vascular Surgery
Peripheral Arterial Disease
DISRUPT PAD III Observational Study
The Disrupt PAD III study was designed as a randomized controlled trial (RCT) with an additional observational registry component.
- Trial name
- PAD III OS (NCT05881421)
- Where
- 30 sites in United States, Germany and 1 more
- Volunteers
- 1,373 people
- Sponsor
- Shockwave Medical, Inc.
Peripheral Arterial Disease
An Investigator Initiated Trial to Evaluate the Safety and Feasibility of the DyNETIC-35 Stent for Iliac Lesions Via a Trans-radial Approach
This feasibility study with a 30 day follow up period will assess the safety and feasibility of the Dynetic-35 stent for the treatment of peripheral iliac artery lesions via a trans-radial approach.
- Trial name
- NCT05372952
- Testing
- Dynetic-35 Peripheral Balloon-Expandable Stent System
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Klinikum Arnsberg
Cardiovascular Diseases, Metabolic Disease
Vascular Lab Resource (VLR) Biorepository
This is a study of biomarkers obtained from prospectively collected subject samples and their correlation with cardiovascular and metabolic diseases.
- Conditions
- Cardiovascular Diseases, Metabolic Disease, Peripheral Artery Disease, Carotid Disease
- Trial name
- NCT05628948
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- The Cleveland Clinic
Peripheral Artery Disease
Online Support for Outpatient Peripheral Arterial Disease Self-management
This study looks to examine whether an online patient tool to monitor factors affecting patients peripheral artery disease can lead to improvements in patients' disease and slow its progression.
- Trial name
- NCT03464006
- Testing
- Online Support Module, Standard of Care
- Volunteers
- 200 people
- Sponsor
- McMaster University
Peripheral Arterial Disease
MitoQ Treatment of Claudication: Myofiber and Micro-vessel Pathology
In our research, we are delving into whether taking MitoQ for six months can improve the symptoms and function of people diagnosed with peripheral artery disease, especially those who suffer from leg pain while walking, known as…
- Trial name
- NCT06409949
- Testing
- Walking assessment, QOL Survey, Ankle pressure at rest and after stress
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Nebraska
Metabolic Syndrome, Coronary Artery Disease
The Effects of Muscle Training in Coronary Artery Patients With Metabolic Syndrome
The aim of this study is to investigate the effects of peripheral and respiratory muscle training on respiratory muscle strength, respiratory functions, exercise capacity and quality of life in coronary artery patients with…
- Trial name
- NCT03523026
- Testing
- Neuromuscular Electrical Stimulation, Inspirator Muscle Training, Peripheral Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medipol University Hospital
Peripheral Arterial Disease
Electrical Stimulation in Peripheral Arterial Disease
The investigators wish to investigate the effects of neuromuscular stimulation on intermittent claudication.
- Trial name
- PAD (NCT02136537)
- Testing
- Bilateral NMES legs, Best medical therapy
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Imperial College London
Peripheral Artery Disease
Comparative Pharmacokinetic Study Between Two Extended-Release Cilostazol Formulations in Korea
This is a randomized, open-label, multiple-dose, two-sequence, two-period crossover study to to compare the safety/tolerability and pharmacokinetics between Pletaal SR Cap. and Cilostan CR Tab. in healthy volunteers
- Trial name
- NCT03524963
- Testing
- Cilostan CR Tab., Pletaal SR Cap.
- Where
- South Korea
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bundang CHA Hospital
Peripheral Artery Disease, Heart Failure
Myocardial Dysfunction Evaluation in Lower Extremity Arterial Disease Patients With Deformation Analysis
Single centre observational study to assess lower extremity arterial disease (LEAD) patients' cardiac dysfunction with strain analyses and to assess connections between cardiac dysfunction, metabolomic changes and target organ…
- Trial name
- MEDAL (NCT06215248)
- Where
- Estonia
- Volunteers
- 162 people
- Sponsor
- Tartu University Hospital
Peripheral Artery Disease, Peripheral Vascular Disease
Absolute Pro® MOMENTUM™
To evaluate the safety and effectiveness of the Absolute Pro® Peripheral Self-Expanding Stent System and the Absolute Pro® LL Peripheral Self-Expanding Stent System for the treatment of subjects with atherosclerotic de novo or…
- Trial name
- MOMENTUM (NCT01444378)
- Testing
- Stenting using Absolute Pro® and Pro LL® Peripheral Stent Systems
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Abbott Medical Devices
Mild Cognitive Impairment, Dementia
Remote Ischemic Conditioning of the Human Brain in Dementia Patients
The study investigates the incidence of remote ischemic conditioning in mild cognitive impairment and dementia patients
- Conditions
- Mild Cognitive Impairment, Dementia, Intermittent Claudication
- Trial name
- RICBDE (NCT04168021)
- Testing
- Leg ischemia
- Volunteers
- 90 people
- Sponsor
- Aristotle University Of Thessaloniki
Peripheral Arterial Disease
Hemodynamic Characteristics of Peripheral Arterial Disease Using Computational Fluid Dynamics
Peripheral arterial disease can reduce blood flow to the legs. This study will examine how blood flow patterns in the leg arteries differ between people with peripheral arterial disease and people without the disease.
- Trial name
- NCT07860138
- Testing
- Computational Fluid Dynamics Simulation
- Where
- China
- Volunteers
- 14 people
- Sponsor
- Fudan University
Critical Limb Ischemia (CLI), Popliteal Nerve Block
Ultrasound-Guided Sciatic Popliteal Nerve Block vs. Erector Spinae Plane Block in Endovascular Management of CLI
Comparison of popliteal sciatic nerve block and erector spinae plane block (ESPB) in patients undergoing endovascular management of critical lower limb ischemia (CLI).
- Conditions
- Critical Limb Ischemia (CLI), Popliteal Nerve Block, ESPB
- Trial name
- NCT06913348
- Testing
- Popliteal sciatic nerve block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Minia University Hospital
Restenosis, Peripheral Arterial Disease
Local Delivery of Paclitaxel Via the TAPAS Catheter to Prevent Restenosis From Percutaneous Femoropopliteal Intervention
The purpose of this study is to assess the safety and efficacy of administering intra-arterial paclitaxel in the femoropopliteal arteries via the TAPAS catheter following percutaneous revascularization to prevent restenosis.
- Trial name
- PacTAP (NCT01599078)
- Testing
- Paclitaxel
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Midwest Cardiovascular Research Foundation
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