Clinical trials: Artery Disease, Peripheral
Peripheral Vascular Disease
Comparison of the SUpera® PERipheral System in the Superficial Femoral Artery
This is a prospective, multicenter, non-randomized, single arm, pivotal trial. The main objective of this study is to demonstrate the safety and effectiveness of the IDev SUPERA® Nitinol Stent System in treating subjects with…
- Trial name
- SUPERB (NCT00933270)
- Testing
- SUPERA® Nitinol Stent System
- Where
- 49 sites in United States
- Volunteers
- 325 people
- Sponsor
- Abbott Medical Devices
Peripheral Arterial Disease
The Role of HSP90 in Peripheral Vascular Lesions of Diabetic Atherosclerosis
Diabetic foot disease with a global incidence of about 6% is one of the most serious complications of diabetes, which brings great pain and economic burden to patients.In China, the incidence rate is 8.1%, and the amputation rate…
- Trial name
- rhsppvlda (NCT04787770)
- Testing
- non-intervention
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Atherosclerotic Cardiovascular Disease (ASCVD), Coronary Heart Disease (CHD)
VICTORION-ASCERTAIN: Implementation Study (v-ASCERTAIN)
The goal of this study is to understand and compare an alternative model of care in comparison to the usual model of care in include male and female participants ≥18 years of age with a history of ASCVD (hear and blood vessels…
- Conditions
- Atherosclerotic Cardiovascular Disease (ASCVD), Coronary Heart Disease (CHD), Cerebrovascular Disease, Peripheral Arterial Disease (PAD)
- Trial name
- v-ASCERTAIN (NCT05834673)
- Testing
- SMS messages, Telephone-based support calls, GP Education
- Where
- Australia
- Volunteers
- 6 people
- Sponsor
- Monash University
Diabetic Neuropathy, Arthritis
Effect of Holofiber Socks and Bedding on Pain and Quality of Sleep in Subjects With Chronic Foot Pain
This study is designed to assess the effects of socks and bedding materials on foot pain, the level of blood oxygen existing in the feet and quality of sleep in subjects who have chronic foot pain from either diabetic neuropathy…
- Conditions
- Diabetic Neuropathy, Arthritis, Peripheral Arterial Disease, Plantar Fasciitis
- Trial name
- NCT00458497
- Testing
- Holofiber fabric, PET fabric
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Southern California Institute for Research and Education
Postoperative Delirium (POD), Peripheral Arterial Disease
Effect of Preoperative Ultrasound-Guided Stellate Ganglion Block on Postoperative Delirium in Older Adults Undergoing Elective Peripheral Endovascular Intervention
This randomized controlled trial will evaluate whether preoperative ultrasound-guided stellate ganglion block reduces the incidence of postoperative delirium in adults aged 60 years or older undergoing elective peripheral…
- Trial name
- NCT07848113
- Testing
- ropivacaine
- Volunteers
- 168 people
- Sponsor
- Assiut University
Peripheral Artery Disease
Bard LifeStent and Lutonix DCB for Treatment of Long Lesions in Femoropopliteal Arteries
Objective of this study is to evaluate the safety and efficacy of Lutonix 035 Drug Coated Dilatation PTA Catheter with Bard LifeStent Vascular Stent (hereinafter referred to as LifeStent) for treatment of long (10-24 cm) lesions…
- Trial name
- NCT02278991
- Testing
- Lutonix Drug Coated Balloon
- Where
- 12 sites in Germany, Greece and 1 more
- Volunteers
- 149 people
- Sponsor
- C. R. Bard
Fall, Fall Injury
Integrating Fall Prevention Balance Exercises Into a Program for Older Adults With Peripheral Artery Disease (PAD): A Mixed Methods Feasibility Study
The overarching objective of this study is to improve fall prevention efforts in community-dwelling older adults with peripheral artery disease (PAD) to reduce falls.
- Conditions
- Fall, Fall Injury, Peripheral Artery Disease, Peripheral Arterial Disease
- Trial name
- NCT05090774
- Testing
- Adapted Otago Exercise Program (OEP)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Minnesota
Pulmonary Arterial Hypertension
Sotatercept on Central Cardiopulmonary Performance and Peripheral Oxygen Transport During Exercise in Pulmonary Arterial Hypertension
The purpose of this study is to see if the drug sotatercept given for 36 weeks improves the functioning of the heart and improves quality of life.
- Trial name
- NCT06409026
- Testing
- Sotatercept
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Claudication, Intermittent, Peripheral Arterial Disease
REmotely Supervised Exercise Therapy Trial 2
Supervised exercise for intermittent claudication is a first line therapy for peripheral arterial disease, as recommended by the National Institute for Health and Clinical Excellence and the European Society for Vascular Surgery.
- Trial name
- RESET2 (NCT04925219)
- Testing
- Remotely supervised exercise programme, Self-directed exercise
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Mid and South Essex NHS Foundation Trust
Peripheral Arterial Disease
Pain and Hemodynamics in Peripheral Arterial Disease: Response to Pulsed Electromagnetic Treatment
patients with peripheral arterial disease are recommended to perform all exercise forms including elliptical type. electromagnetic treatment addition to exercise may increase benefits of this exercise
- Trial name
- NCT06252181
- Testing
- electromagnetic pulsed therapy, elliptical exercise
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ahram Canadian University
Peripheral Arterial Disease
The AbsorbaSeal Vascular Closure Device Trial
This study investigates the efficacy and safety of the AbsorbaSeal 6Fr Vascular Closure device (VCD) for the closure of access site of patients requiring percutaneous diagnostic or interventional procedures.
- Trial name
- NCT03730571
- Testing
- AbsorbaSeal 6Fr Vascular Closure Device
- Where
- 3 sites in Belgium
- Volunteers
- 9 people
- Sponsor
- ID3 Medical
Peripheral Arterial Disease
Debulking Atherectomy Versus Stent Angioplasty for Limb Ischaemia of Diabetic Lower Limb Atherosclerosis-occlusive Disease.
In order to assessment the safety and efficacy of debulking atherectomy versus stent angioplasty for limb ischaemia of diabetic lower limb atherosclerosis-occlusive disease, we intend to conduct a prospective, multicenter…
- Trial name
- NCT05670171
- Testing
- Debulking Atherectomy, Stent Angioplasty
- Where
- 10 sites in China
- Volunteers
- 244 people
- Sponsor
- Xuanwu Hospital, Beijing
Peripheral Artery Disease
3-year Follow-up of Patients Treated With Jetstream Combined With Ranger for Calcified Femoropopliteal Lesions
The goal of this non interventional study is to evaluate the long-term clinical effects (3-year follow-up after the procedure) of Jetstream atherectomy combined with a paclitaxel-eluting balloon (Ranger) in all patients who were…
- Trial name
- FIDJI (NCT06173960)
- Testing
- atherectomy
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Association de Provence pour la Promotion de l'Enseignement et la Recherche Cardiologique
Peripheral Arterial Disease
Paclitaxel Coated Balloon Catheter for Prevention of Restenosis in Femoropopliteal Arteries
The PACCOCATH FEM study is a randomized, double-blinded German multicenter trial on the efficacy and tolerance of a paclitaxel coated balloon catheter in prevention of restenosis after femoropopliteal angioplasty.
- Trial name
- PACCOCATH_F (NCT00472472)
- Testing
- paclitaxel coated balloon catheter (device with drug)
- Where
- 2 sites in Germany
- Volunteers
- 87 people
- Sponsor
- University Hospital, Saarland
Peripheral Artery Disease
Leg Heat Therapy in Peripheral Artery Disease
The goal of this randomized, double-blind, sham-controlled clinical trial is to evaluate the benefits of home-based, leg heat therapy (HT) on lower-extremity functioning and quality of life in patients who suffer from…
- Trial name
- NCT05465070
- Testing
- Leg heat therapy
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Indiana University
Herpes Zoster, Dementia
Postherpetic Neuralgia After Herpes Zoster and Incident Dementia Risk
This retrospective observational cohort study uses de-identified electronic health record data from the TriNetX Global Collaborative Network to evaluate whether postherpetic neuralgia after herpes zoster is associated with an…
- Conditions
- Herpes Zoster, Dementia, Postherpetic Neuralgia (PHN)
- Trial name
- NCT07399288
- Testing
- Exposure: postherpetic neuralgia
- Where
- Taiwan
- Volunteers
- 73,404 people
- Sponsor
- China Medical University Hospital
Androgen Receptor Abnormal, Insulin-Like Growth Factor I Deficiency
AR, IGF-IR, IR and Peripheral Artery Disease
Peripheral artery Disease (PAD) is a major cardiovascular disease that can impair quality of life (QoL). It affects more often male patients and its pathophysiology is not completely known.
- Conditions
- Androgen Receptor Abnormal, Insulin-Like Growth Factor I Deficiency, Insulin Receptor, Defect in
- Trial name
- ANIMALPAD (NCT04710186)
- Testing
- arterial reconstructive open surgery
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Catanzaro
Peripheral Arterial Disease
A Single-dose Escalation Safety and PK Study for PLC in Healthy Chinese
The main objective is to evaluate the effect of single dose Propionyl-L-Carnitine Hydrochloride on clinical pharmacokinetic characteristics and its effect of clinical pharmacokinetic characteristics and safety on healthy Chinese…
- Trial name
- NCT02786069
- Testing
- Propionyl L-carnitine Hydrochloride
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Lee's Pharmaceutical Limited
Peripheral Arterial Disease
DANCE Partner: Inflammatory Biomarker Analysis by Femoropopliteal Revascularization Method and Treatment Outcomes
This is a prospective, multi-center, observational registry to document the baseline, 24-hour and 30-day inflammatory response and procedural outcomes out to 12 month follow-up after femoropopliteal angioplasty or…
- Trial name
- NCT02469532
- Testing
- Balloon Angioplasty, Atherectomy System
- Where
- 6 sites in United States
- Volunteers
- 31 people
- Sponsor
- Mercator MedSystems, Inc.
Peripheral Arterial Disease
MyPADMGT Support of Out-Patients With Peripheral Arterial Disease
The investigators have developed an online program to help people with peripheral arterial disease (PAD) in their extremities to better self-manage their condition.
- Trial name
- Final_PADHSS (NCT04228549)
- Testing
- MyPADMGT, MyPADMGT + Nudging
- Where
- Canada
- Volunteers
- 126 people
- Sponsor
- McMaster University
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