Clinical trials: Artery Disease, Peripheral
Peripheral Arterial Disease
Multi-center Study for Stent Graft System for Peripheral Artery
The utility of GP1101 will be evaluated relative to that of surgical bypass in the treatment of Femoral/Popliteal Arterial Symptomatic Peripheral Arterial Disease.
- Trial name
- VJH11-01 (NCT01575808)
- Testing
- GP1101
- Where
- 15 sites in Japan
- Volunteers
- 133 people
- Sponsor
- W.L.Gore & Associates
Blood Pressure, Ischemic Stroke
Comparison of Peripheral and Cerebral Arterial Flow in Acute Ischemic Stroke: Fimasartan vs. Valsartan vs. Atenolol
Confirm central blood pressure reduction effect of Fimasartan, Valsartan and Atenolol and compare correlation with the measured peripheral (central blood pressure, pulse wave velocity, and flow-mediated dilation) and cerebral…
- Trial name
- FAVOR (NCT02403349)
- Testing
- Fimasartan, Valsartan, Atenolol
- Volunteers
- 105 people
- Sponsor
- Ajou University School of Medicine
Peripheral Arterial Occlusive Disease
Retrospective Safety Survey In Patients Included In NV1FGF Clinical Trials
The objective of this study is to collect retrospectively long term safety data in patients who have participated in the previous phase I-II trials conducted with the compound.
- Trial name
- TALISMAN S (NCT01135797)
- Where
- 7 sites in United States, Belgium and 5 more
- Volunteers
- 164 people
- Sponsor
- Sanofi
Symptomatic Peripheral Arterial Disease, Occlusive Disease of Artery of Lower Extremity
IDOMENEO - Is Treatment Reality in Vascular Medicine Evidence-based and Follows Guideline Recommendations? A Project for Quality Development Exemplified by Peripheral Arterial Disease (PAD)
The prevalence of peripheral arterial disease (PAD) and the proportion of endovascular procedures for treatment are increasing worldwide.
- Conditions
- Symptomatic Peripheral Arterial Disease, Occlusive Disease of Artery of Lower Extremity, Quality of Life
- Trial name
- IDOMENEO (NCT03098290)
- Testing
- Catheter-based endovascular revascularization, Bypass-Surgery, Endarterectomy
- Where
- 35 sites in Germany
- Volunteers
- 5,608 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Peripheral Arterial Occlusive Disease
Ovine Graft (Omniflow II) Versus PTFE in Below Knee Arterial Reconstruction
The study intends to compare commonly used PTFE grafts with the biologic ovine graft Ominiflow II for below-knee bypass surgery in patients with peripheral artery occlusive disease with no autologous vein graft available.
- Trial name
- NCT00845585
- Testing
- Below Knee Arterial Reconstruction
- Where
- Switzerland
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Peripheral Arterial Disease
Exercise Therapy in Patients With Peripheral Artery Disease: Evaluating the Clinical Effectiveness of Exercise Therapy and Exploring Determinants of Improvement
I. To investigate whether patient characteristics, exercise therapy characteristics, local metabolic exercise response, endothelial function, autonomic function or atherosclerotic lesion location can predict the walking response…
- Trial name
- PROSECO (NCT03995589)
- Testing
- Walking, Control
- Where
- Belgium
- Volunteers
- 59 people
- Sponsor
- KU Leuven
Intermittent Claudication, Peripheral Vascular Disease
Extract of Ginkgo Biloba (EGB 761) and Vascular Function
This study will determine if a highly standardized herbal extract of the leaves of the Ginkgo Biloba tree will benefit patients who have pain on walking due to narrowing of the arteries of the legs.
- Trial name
- NCT00029991
- Testing
- Gingko Biloba (Herb)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Peripheral Vascular Diseases, Cardiovascular Diseases
Effectiveness of Group Walking Sessions for Increasing Activity in People With Peripheral Arterial Disease (The Group Oriented Arterial Leg Study [GOALS])
Lower extremity peripheral arterial disease (PAD) is a disease in which fatty build-up, or plaque, accumulates in the arteries of the legs.
- Trial name
- NCT00693940
- Testing
- Group mediated cognitive behavioral (GMCB) sessions, Health education sessions
- Where
- United States
- Volunteers
- 194 people
- Sponsor
- Northwestern University
Coronary Artery Disease
In-human Validation of a Technique for Measuring Central Aortic Hemodynamics With Peripheral Arterial Waveforms
Central aortic blood pressure (BP) and flow are generally more informative about the health condition of the heart and the arterial system compared with BP measured in peripheral locations (e.g. arm or leg).
- Trial name
- NCT01567748
- Testing
- BP Measurements at aorta, radial and femoral locations
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Alberta
Peripheral Artery Disease, Clopidogrel, Poor Metabolism of
The Value of Screening for HPR in Patients Undergoing Lower Extremity Arterial Endovascular Interventions
This is a randomized controlled trial designed to evaluate the role of screening for and intervening on patients with high on treatment platelet reactivity undergoing lower extremity arterial endovascular interventions.
- Conditions
- Peripheral Artery Disease, Clopidogrel, Poor Metabolism of, Peripheral Vascular Disease, Artery Disease
- Trial name
- NCT04007055
- Testing
- Point of care screening for HPR, Ticagrelor 90mg
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Marissa Jarosinski
Peripheral Arterial Disease, Intermittent Claudication
Study to Evaluate the Lower Extremity Intervention With Integrated Embolic Protection Using the Vanguard IEP System
The ENTRAP Study is a prospective, multi-center, non-randomized, single-arm, study with follow-up to 30 days to determine the acute safety, acute device performance and clinical performance of the Vanguard IEP Peripheral Balloon…
- Conditions
- Peripheral Arterial Disease, Intermittent Claudication, Atherosclerosis of Femoral Artery
- Trial name
- ENTRAP (NCT03271710)
- Testing
- peripheral balloon angioplasty
- Where
- 9 sites in Belgium, Germany
- Volunteers
- 113 people
- Sponsor
- Contego Medical, Inc.
Peripheral Arterial Disease
SAFE (Sarpogrelate Anplone in Femoro-popliteal Artery Intervention Efficacy) Study
After endovascular treatment (EVT) for peripheral artery disease (PAD), dual antiplatelet therapy (DAAT) of aspirin (ASA) and clopidogrel are currently drug of choice to prevent occlusion.
- Trial name
- NCT02959606
- Testing
- Sarpogrelate SR 300mg, Clopidogrel
- Where
- South Korea
- Volunteers
- 272 people
- Sponsor
- Seoul National University Hospital
Peripheral Arterial Disease
Efficacy and Safety Study of NV1FGF in Patients With Severe Peripheral Artery Occlusive Disease
This study is a double-blind study to evaluate the efficacy and safety of NV1FGF, a pCOR plasmid constructed by inserting the gene coding for the FGF compared to placebo in patients with severe Peripheral Arterial Occlusive…
- Trial name
- TALISMAN 201 (NCT00368797)
- Testing
- XRP0038 (NV1FGF)
- Where
- 6 sites in Belgium, France and 4 more
- Volunteers
- 125 people
- Sponsor
- Sanofi
Peripheral Arterial Disease
Near-Infrared Spectroscopy-Guided Exercise Training in Peripheral Arterial Disease
Background: Patients suffering with atherosclerotic peripheral arterial disease (PAD) have limited therapeutic options to improve claudication.
- Trial name
- NCT03478085
- Testing
- Oxygen guided exercise therapy
- Volunteers
- 18 people
- Sponsor
- Augusta University
Peripheral Arterial Disease, Aging
SMART Exercise for PAD
Supervised exercise therapy (SET), consisting of treadmill exercise conducted three times weekly at a center while supervised by healthcare personnel, is first line therapy for people disabled by lower extremity peripheral artery…
- Conditions
- Peripheral Arterial Disease, Aging, Peripheral Vascular Diseases, Walking, Difficulty
- Trial name
- NCT06032065
- Testing
- Supervised Treadmill Exercise, Home-Based Exercise, Nitrate-rich beetroot Juice
- Where
- 3 sites in United States
- Volunteers
- 210 people
- Sponsor
- Northwestern University
Critical Limb-Threatening Ischemia, Critical Limb Ischemia
Evaluation of the MAGNITUDE® Bioresorbable Drug-Eluting Scaffold in the Treatment of Patients With Below the Knee Disease in Australia
The objective of this prospective, multi-center, clinical investigation is to evaluate the MAGNITUDE BRS System for the planned treatment of narrowed infrapopliteal lesions.
- Conditions
- Critical Limb-Threatening Ischemia, Critical Limb Ischemia, Critical Lower Limb Ischemia
- Trial name
- MAGNITUDE-BTK (NCT06075940)
- Testing
- MAGNITUDE BRS
- Where
- Australia
- Volunteers
- 30 people
- Sponsor
- R3 Vascular Inc.
Peripheral Artery Disease, Vascular Disease
Intima Versus Adventitia Drug Delivery to Elucidate Mechanisms of Restenosis: Magnetic Resonance Imaging
This is a prospective, multicenter, randomized trial to determine the mechanisms of vascular healing. The study will evaluate subjects with peripheral artery disease (PAD) who require an endovascular intervention of the…
- Conditions
- Peripheral Artery Disease, Vascular Disease, Critical Limb Ischemia
- Trial name
- INVADER_MRI (NCT02807779)
- Testing
- Dexamethasone infusion, Drug coated balloon, Plain balloon angioplasty
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- University of California, San Francisco
Intermittent Claudication, Peripheral Artery Disease
A Study of GFH312 in Patients With Peripheral Artery Disease (PAD) and Intermittent Claudication (IC)
GFH312 could be a novel therapeutic option in the acute/chronic inflammatory process of atherosclerosis and provides potential beneficial effects to microvasculature function for PAD patients with IC in addition to preventing…
- Trial name
- NCT05618691
- Testing
- GFH312
- Where
- United States
- Sponsor
- Zhejiang Genfleet Therapeutics Co., Ltd.
Peripheral Vascular Diseases
Plaque Removal Versus Open Bypass Surgery For Critical Limb Ischemia
To compare the outcome of bypass surgery and plaque excision for treatment of critical limb ischemia in the lower limbs
- Trial name
- PROOF (NCT00504088)
- Testing
- Bypass, Silverhawk Plaque Excision
- Where
- 31 sites in United States
- Sponsor
- FoxHollow Technologies
Peripheral Arterial Diseases
The Jetstream (JET) Post-market Registry
The scope of the JET registry to observe long term treatment effects of Jetstream Navitus on various lesions types/morphologies.
- Trial name
- JET (NCT01436435)
- Testing
- Jetstream Atherectomy System
- Where
- 11 sites in United States
- Volunteers
- 241 people
- Sponsor
- Boston Scientific Corporation
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.