Clinical trials: Artery Disease, Peripheral
Peripheral Arterial Disease
Non-invasive Cardiac Screening in High Risk Patients -The GROUND Study
The purpose of this study is to find out if subjecting cardiac high risk patients to non invasive cardiac imaging, followed by treatment will improve survival and quality of life
- Trial name
- NCT00189111
- Testing
- Cardiac Imaging + Treatment
- Where
- 5 sites in Netherlands
- Volunteers
- 1,200 people
- Sponsor
- Clinical Research Office Imaging Division
Peripheral Arterial Disease
TurboPower + DCB Treatment of Femoropopliteal De Novo/ Restenotic and In-Stent Restenosis Lesions
A retrospective study to evaluate Turbo Power laser atherectomy + drug coated balloon (DCB) angioplasty for the treatment of femoropopliteal de novo/restenotic lesions and in-stent restenosis (ISR).
- Trial name
- NCT03306199
- Testing
- Laser Atherectomy
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Spectranetics Corporation
Type 2 Diabetes, Obstructive Sleep Apnea (OSA)
Screening for Obstructive Sleep Apnea in High-risk Patients in a Danish Rural Population: A Pilot Feasibility Study
Background: Obstructive sleep apnea (OSA) is a sleep disorder characterized by recurrent collapse of the upper airway during sleep, resulting in intermittent hypoxia and fragmented sleep.
- Trial name
- NCT07778121
- Testing
- Home Sleep Apnea Test
- Where
- Denmark
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Peripheral Artery Disease
Community Walking Exercise for Patients With Peripheral Artery Disease
The primary aim of the study is to determine the effect of a community-based walking exercise program with detailed training, monitoring, and coaching (TMC) exercise components enhanced by community-based participatory research…
- Trial name
- GAIT (NCT02075502)
- Testing
- Exercise therapy, lower extremity ET, peripheral open intervention
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Minnesota
Peripheral Arterial Occlusive Disease, Chronic Limb-Threatening Ischemia
Safety of Antithrombotic Heparin Proteoglycan Mimetic APAC in Peripheral Arterial Occlusive Disease and Chronic Limb-threatening Ischemia
The goal of this study is to learn if a new medicine (called antiplatelet and anticoagulant [APAC]) can help the body to prevent blood clots and whether APAC is safe and well tolerated in patients with blocked or narrowed…
- Trial name
- HEALING (NCT07352800)
- Testing
- APAC - dose level 0.50 mg/kg,, Unfractionated heparin (UFH), APAC dose level 1: 0.25 mg/kg,
- Where
- 3 sites in Finland
- Volunteers
- 42 people
- Sponsor
- Aplagon Oy
Peripheral Artery Disease, Critical Limb Ischemia
Platelet Reactivity in PAD Undergoing Percutaneous Angioplasty
Dual antiplatelet therapy has a key role in a prevention of thrombosis of treated artery in patients undergoing percutaneous transluminal angioplasty (PTA).
- Conditions
- Peripheral Artery Disease, Critical Limb Ischemia, Claudication, Intermittent
- Trial name
- PAD (NCT04165629)
- Testing
- Aspirin 300mg and Clopidogrel 300mg
- Where
- Serbia
- Volunteers
- 450 people
- Sponsor
- Clinical Centre of Serbia
Peripheral Arterial Disease, Atherosclerosis
Efficacy of Self-Expanding Nitinol S.M.A.R.T CONTROL Stent Versus Life Stent For The Atherosclerotic Femoro-Popliteal Arterial Disease
The nitinol stent has proven superior primary patency than balloon angioplasty in superficial femoral artery lesions. Recent stent design improvements focus on decreasing stent fracture rates which can negatively impact patency…
- Trial name
- SENS-FP-2 (NCT01653600)
- Testing
- S.M.A.R.T CONTROL Stent, LifeStent
- Where
- South Korea
- Volunteers
- 346 people
- Sponsor
- Korea University Guro Hospital
Peripheral Artery Disease
Paclitaxel-eluting Balloon Angioplasty With Provisional Use of Nitinol Stent Versus Systematic Implantation of Paclitaxel-eluting Stent for the Treatment of Femoropopliteal de Novo Lesions
To determine in patients with symptomatic femoropopliteal lesions whether percutaneous revascularization with paclitaxel-eluting balloon angioplasty (PEB) and provisional nitinol stent is superior with respect to the 12-month…
- Trial name
- NCT01969630
- Testing
- PEB, PES
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Ospedale San Donato
Aging, Aortic Aneurysm, Abdominal
The Intersectional Viborg Screening Program: Cost-(Effectiveness) of Screening for Diabetes and Cardiovascular Diseases
This is an intersectional and interdisciplinary screening program in Viborg Municipality, including 67 years old citizens. This observational study will estimate the cost-effectiveness of a combined screening program for the…
- Conditions
- Aging, Aortic Aneurysm, Abdominal, Hypertension, Mass Screening
- Trial name
- VISP (NCT03395509)
- Where
- Denmark
- Volunteers
- 4,500 people, healthy volunteers welcome
- Sponsor
- Central Jutland Regional Hospital
Peripheral Arterial Disease
A Non-significant Risk Clinical Study to Assess Perfusion Changes With Application of a TUS for Patients With PAD
The objective of the clinical trial is to gather evidence on the safety, performance and clinical efficacy Vibrato Sleeve TUS in people with peripheral artery disease (PAD).
- Trial name
- Concerto (NCT05100745)
- Testing
- Therapeutic Device
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Vibrato Medical, Inc.
Peripheral Arterial Disease, Peripheral Vascular Diseases
Mind Body Program for Vascular Disease
The purpose of the current study is to conduct a proof-of-concept test regarding the delivery of a Mind Body Program for vascular disease, focusing on support for depression, stress, and adherence, as part of patients' chronic…
- Trial name
- NCT05757752
- Testing
- Problem Solving Therapy and Integrated Care
- Where
- United States
- Sponsor
- Yale University
Critical Limb Ischemia (CLI)
Critical Limb Ischemia Rapid Delivery by SurgWerks-CLI Kit and VXP System
This is a prospective, double-blinded, randomized, placebo-controlled, multi-center, pivotal clinical study in which subjects are evaluated for prevention of major limb amputation in the treatment of non-reconstructable…
- Trial name
- CLIRST III (NCT02538978)
- Testing
- Autologous Bone Marrow Concentrate (aBMC)
- Volunteers
- 224 people
- Sponsor
- Cesca Therapeutics, Inc.
Peripheral Collaterals, Arteriogenesis
Assessment of Natural Bypasses in the Lower Limb
Concerning the promotion of peripheral collateral growth, clinical studies investigating new therapeutic strategies have used imprecise assessment methods and therefore determined only "weak" endpoints.
- Conditions
- Peripheral Collaterals, Arteriogenesis, Coronary Artery Disease
- Trial name
- NCT01742455
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Chronic Limb Threatening Ischemia
Clinical Outcomes Following Surgical Debridement of Diabetic Foot Infection with Borderline Vascularity
Observe Timing to complete healing of wounds \& Limb salvage in both cohorts those who are undergoing Debridement only and those who are undergoing Debridement plus PTA
- Trial name
- NCT05553509
- Testing
- PER CUTANEOUS TRANSLUMINAL ANGIOPLASTY
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Assiut University
Peripheral Arterial Disease
Clinical and MRI Cardiac Biomarkers on Peripheral Arterial Disease in Patients With Long Term DM
The aim of this study is to establish a clinically feasible simultaneous evaluation of heart and lower limb using MRI and to assess the combined benefit of clinical and cardiac MRI imaging markers in the evaluation of PAD and…
- Trial name
- CMRPADDM (NCT02850432)
- Testing
- Invasive treatment, Conservative treatment
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Peripheral Arterial Disease, Restenosis
Local Paclitaxel Delivery to Prevent Restenosis in Peripheral Arterial Disease
The purpose of this study is to determine if the addition of a catheter-based local delivery of paclitaxel into the peripheral arterial vessels in patients with peripheral arterial disease (PAD) and subsequent restenosis of the…
- Trial name
- ResTAP (NCT03858764)
- Sponsor
- Jane Phillips Medical Center
Vascular Disease, Peripheral
3 Month PHI PAD PoM Study
This is a multi-center, randomized, blinded, placebo controlled study to evaluate the safety of GSK1278863 and its acute and short-term (e.g.
- Trial name
- NCT02135848
- Testing
- GSK1278863
- Where
- 12 sites in United States
- Volunteers
- 46 people
- Sponsor
- GlaxoSmithKline
Peripheral Angioplasty, Pain Management
Virtual Reality for Pain and Anxiety Relief During Peripheral Angioplasty
Peripheral arterial disease can cause serious leg pain and discomfort. During treatment with angioplasty, patients often feel pain and anxiety because the procedure is usually done with local anesthesia and no sedation.
- Conditions
- Peripheral Angioplasty, Pain Management, Virtual Reality
- Trial name
- VRPAIN (NCT07057752)
- Testing
- Virtual Reality, dexketoprofen + midazolam
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Kastamonu University
Peripheral Arterial Disease (PAD), Moderate Risk for Cardiovascular Disease (CVD)
Prevalence of Peripheral Arterial Disease in Subject With a Moderate Risk of Cardiovascular (CV) Disease (CVD) in Primary Prevention
Non interventional study aimed to establish the prevalence of lower extremity peripheral arterial disease (PAD), defined as an ankle-brachial index (ABI) not above 0.90 in subjects with a moderate risk of cardiovascular disease…
- Trial name
- PANDORA (NCT00689377)
- Where
- 331 sites in Belgium, France and 4 more
- Volunteers
- 9,000 people
- Sponsor
- AstraZeneca
Peripheral Arterial Disease, Diabetic Angiopathies
Evaluating Bu Yang Huanwu Decoction For Early Diabetic Vascular Disease
The goal of this clinical trial is to learn if adding a Traditional Chinese Medicine formula, Bu Yang Huanwu Decoction (specifically the capsule form called Hua Yu Wan Capsule), to standard treatment can help prevent leg pain at…
- Conditions
- Peripheral Arterial Disease, Diabetic Angiopathies, Arterial Occlusive Diseases
- Trial name
- NCT07658807
- Testing
- Hua Yu Wan Capsule, Aspirin
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Xuanwu Hospital, Beijing
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