Clinical trials: Artery Stenosis
Coronary Artery Disease, Myocardial Infarction
Clinical Evaluation of Radiation Reduction for Optimized Safety
The primary objective of this study is to determine whether a reduced radiation protocol (RRP) in which angiograms are acquired at ultralow radiation doses and then processed using spatiotemporal enhancement software can produce…
- Conditions
- Coronary Artery Disease, Myocardial Infarction, Coronary Disease, Coronary Stenosis
- Trial name
- CERROS (NCT06348875)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Angiowave Imaging
Peripheral Arterial Disease, Carotid Stenosis
EValuation of Systemic Atherothrombosis in Patients With ARTerial Disease of the Lower Limbs
The purpose of this study is to determine the prevalence and risk factors, at the time of the diagnosis of PAD, for asymptomatic carotid stenosis and abdominal aortic aneurysm.
- Conditions
- Peripheral Arterial Disease, Carotid Stenosis, Abdominal Aortic Aneurysm
- Trial name
- EVART (NCT01224600)
- Testing
- patients with newly diagnosed PAD (<1year)
- Where
- 115 sites in Belgium, France
- Volunteers
- 1,056 people
- Sponsor
- Institut de l'Atherothrombose
Carotid Artery Stenosis
Ultrasound-guided Intermediate Cervical Plexus Block for Carotid Surgery
Since stroke and myocardial ischemia are major causes of perioperative morbidity and mortality associated with carotid endarterectomy, monitoring the brain and ensuring the best hemodynamic stability are important goals of…
- Trial name
- NCT02450734
- Testing
- Ultrasound-guided intermediate cervical plexus block
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Institut Mutualiste Montsouris
Ischemic Stroke, Carotid Stenosis
Radial Versus Femoral Access For Carotid Artery Stenting
Background: For moderate to severe carotid artery atherosclerotic stenosis, in the past decades, carotid artery stenting (CAS) has been an alternative to carotid endarterectomy (CEA) for the treatment of carotid artery stenosis.
- Conditions
- Ischemic Stroke, Carotid Stenosis, Cerebral Revascularization, Carotid Artery Diseases
- Trial name
- RACE-CAS (NCT05416853)
- Testing
- Carotid Artery Stenting (CAS)
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- The First Affiliated Hospital of University of Science and Technology of China
Internal Carotid Artery Stenosis
The Observation About the Effects of Internal Carotid Artery Stenosis on Fundus Vessels and the Changes of Fundus Vessels After Interventional Therapy
The investigators plan to collect 30 participants with internal carotid artery stenosis to observed the relationship between the degree of internal carotid artery stenosis and fundus vessels （and blood flow）density before…
- Trial name
- NCT05260229
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Coronary Artery Stenosis
The Real-world Firebird 2 Versus Cypher Sirolimus-eluting Stent in Treating Patients With Coronary Artery Disease
Sirolimus-eluting stent (SES) has been world-widely used in clinical practice in treating patients with coronary artery disease (CAD).
- Trial name
- REFIRE (NCT01328730)
- Testing
- Firebird 2 SES, Cypher SES
- Where
- China
- Volunteers
- 430 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Asymptomatic, Artery
Stenting Versus Best Medical Treatment of Asymptomatic High Grade Carotid Artery Stenosis
Background. Carotid artery stenting (CAS) recently has become an accepted method for treatment of patients with high-grade carotid artery stenosis, who are at an increased risk for surgical carotid endarterectomy (CEA).
- Trial name
- NCT00497094
- Testing
- carotid artery stenting
- Where
- Austria
- Volunteers
- 148 people
- Sponsor
- Vienna General Hospital
Diagnosis Coronary Artery Disease
Diagnostic Performances of Computed TomographIc Coronary Angiography and Intravascular Ultrasound
Diagnostic purposes of the coronary angiography is to detect stenosis (anatomy) and to detect ischemia related stenosis (function). Coronary angiography (CAG) is a gold standard invasive techniques, but has several limitations.
- Trial name
- IMAGES-FFR (NCT01400230)
- Testing
- diagnostic procedures CCTA, CAG, IVUS and FFR
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Seoul National University Hospital
Coronary Bypass Graft Stenosis
Optical Coherence Tomography of the Saphenous Vein Graft
OCTOCAB is a prospective, randomized (1:1), single-center trial. The purpose of this study is to determine whether intravascular optical coherence tomography (OCT) guided saphenous vein grafting in coronary artery bypass surgery…
- Trial name
- OCTOCAB (NCT05129228)
- Testing
- OCT-guided saphenous vein CABG
- Where
- United States
- Volunteers
- 760 people
- Sponsor
- St. Francis Hospital, New York
Coronary Artery Disease, Coronary Stenosis
Maastricht Biomarker CT Study
Introduction Cardiovascular disease is the leading cause of death in the Western world. The main cause for cardiovascular events is the development of atherosclerosis in the coronary arteries.
- Trial name
- NCT01671930
- Where
- Netherlands
- Volunteers
- 5,000 people
- Sponsor
- Maastricht University Medical Center
Renal Artery Stenosis, Aortic Dissection
On-table Renal Perfusion Evaluation Renal Artery Stenosis or Obstruction
1. Evaluate the feasibility for the on-table evaluation of the renal perfusion by using Syngo Dyna Parenchymal Blood Volume(PBV) Body; 2.
- Conditions
- Renal Artery Stenosis, Aortic Dissection, Renal Perfusion, Renal Artery Obstruction
- Trial name
- NCT03530748
- Testing
- Endovascular therapy and Imaging Acquisition
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Zhongshan Hospital
Coronary Disease, Coronary Artery Disease
SIROOP Registry - A Prospective Registry Study to Evaluate the Outcomes of Coronary Artery Disease Patients Treated With SIROlimus Or Paclitaxel Eluting Balloon Catheters
The purpose of the SIROOP Registry is to retrospectively and prospectively collect baseline, clinical and procedural characteristics of patients who have undergone PCI and are treated with either currently available sirolimus or…
- Conditions
- Coronary Disease, Coronary Artery Disease, Coronary Restenosis, Coronary Arteriosclerosis
- Trial name
- SIROOP (NCT04988685)
- Testing
- Sirolimus Eluting Balloon
- Where
- Switzerland
- Volunteers
- 2,000 people
- Sponsor
- Luzerner Kantonsspital
Coronary Arterial Disease (CAD)
Non-invasive Detection of Coronary Artery Stenosis
The aim of this viability study is to investigate using a novel medical device, the potential for detecting partial blockages in the arteries within the wall of the heart (coronary artery stenosis).
- Trial name
- NIDCAS (NCT06750016)
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Nilocas
Carotid Stenosis, Carotid Artery Diseases
Ultrafast Ultrasound Imaging Assesment of Carotid Plaque Neovascularization
Stroke is the second leading cause of death in the Western world and the leading cause of major lifelong disability. About 15% of strokes are secondary to thrombosis or embolization of an unstable atheromatous carotid plaque.
- Conditions
- Carotid Stenosis, Carotid Artery Diseases, Carotid Atherosclerosis, Carotid Artery Plaque
- Trial name
- ULTRA-VASC (NCT04470687)
- Testing
- contrast enhanced ultrafast ultrasound imaging
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Coronary Artery Disease, Coronary Artery Stenosis
Study of the No-touch Saphenous Vein Graft
Authors hypothesize that "no-touch" saphenous vein as I graft is superior over conventional "no-touch" saphenous vein as free graft in the incidence of graft patency.
- Conditions
- Coronary Artery Disease, Coronary Artery Stenosis, Graft Failure, Cardiac Ischemia
- Trial name
- NCT05757947
- Testing
- Сoronary bypass surgery according to the I-graft method, Сoronary bypass surgery by the method of free conduit
- Where
- Russia
- Volunteers
- 106 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Carotid Stenosis
Evaluation of the TriActiv ProGuard System During Carotid Artery Stenting
The purpose of this study is to evaluate the safety and efficacy of the TriActiv® ProGuard™ System when used during a stent placement in a blockage within the carotid artery in patients considered to be at high risk for…
- Trial name
- NCT00395785
- Testing
- Carotid Stent Implantation, Embolic Protection
- Where
- 34 sites in United States, Germany
- Volunteers
- 400 people
- Sponsor
- Kensey Nash Corporation
Coronary Artery Disease
Treatment of Coronary De-novo Stenosis by a Sirolimus Coated Balloon or a Paclitaxel Coated Balloon Catheter
To examine the treatment of coronary de-novo stenosis with a sirolimus coated balloon versus a paclitaxel coated balloon
- Trial name
- SCBDENOVO (NCT03908450)
- Testing
- PTCA of coronary de novo lesion PCB, PTCA of coronary de novo lesion SCB
- Where
- 4 sites in Germany, Switzerland
- Volunteers
- 70 people
- Sponsor
- InnoRa GmbH
Carotid Stenosis
Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial
Carotid revascularization for primary prevention of stroke (CREST-2) is two independent multicenter, randomized controlled trials of carotid revascularization and intensive medical management versus medical management alone in…
- Trial name
- CREST-2 (NCT02089217)
- Testing
- Carotid endarterectomy (CEA), Carotid Stenting (CAS), Intensive Medical Management - no CEA
- Where
- 167 sites in United States, Australia and 3 more
- Volunteers
- 2,486 people
- Sponsor
- Mayo Clinic
Choroid, Carotid Stenosis
Ocular Effects of Carotid Endarterectomy
All patients undergoing carotid endarterectomy in Shaare Zedek Medical Hospital, during about 1 year, will be offered to participate. Retinal and choroidal structural changes will be assessed using swept-source OCT technology
- Conditions
- Choroid, Carotid Stenosis, Carotid Endarterectomy
- Trial name
- NCT02448355
- Testing
- OCT swept source DRI-Atlantis, Topcon
- Volunteers
- 30 people
- Sponsor
- Shaare Zedek Medical Center
Stable Angina Pectoris, Unstable Angina Pectoris
Non-invasive Diagnosis of Coronary Artery Stenoses by Doppler Echocardiography
Non-invasive evaluation of patients with stable angina and unstable coronary syndromes with transthoracic Doppler echocardiography to evaluate presence of significant coronary stenoses.
- Conditions
- Stable Angina Pectoris, Unstable Angina Pectoris, Acute Myocardial Infarction
- Trial name
- NCT00281346
- Testing
- Doppler echocardiography
- Where
- Norway
- Volunteers
- 110 people
- Sponsor
- Norwegian University of Science and Technology
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