Clinical trials: Artery Stenosis
Ischemic Stroke
Bare -Metal Stents and Drug -Eluting Stents in the Treatment of Patients With Vertebral Artery Ostium Stenosis
The study hypothesizes that Drug -eluting stents are more effective in preventing restenosis than Bare-metal stents after Vertebral Artery Ostium stenting
- Trial name
- NCT02197559
- Testing
- DES group, BMS group
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Xuanwu Hospital, Beijing
Intracranial Atherosclerosis, Cognitive Impairment
Cognitive Decline and Underlying Mechanisms in Symptomatic Intracranial Artery Stenosis Patients: A Cohort Study
The purpose of this study is to explore the mechanism of cognitive impairment in patients with symptomatic intracranial atherosclerotic stenosis (ICAS), and further plans to explore the impact of different treatment options on…
- Conditions
- Intracranial Atherosclerosis, Cognitive Impairment, Cerebrovascular Event
- Trial name
- NCT06336174
- Testing
- Aspirin Tablet, Clopidogrel Bisulfate Tablets and Atorvastatin, Endovascular therapy,Aspirin Tablet, Clopidogrel Bisulfate Tablets and Atorvastatin
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Anhui Medical University
Carotid Artery Stenosis
Evaluation of the Ton-bridge Carotid Stent for Carotid Artery Stenosis
The purpose of this trial is to evaluate effectiveness and safety of the Ton-bridge carotid stent for the treatment of carotid artery stenosis.
- Trial name
- NCT06365697
- Testing
- Ton-bridge carotid stent, WALLSTENT carotid stent
- Where
- 7 sites in China
- Volunteers
- 188 people
- Sponsor
- Ton-Bridge Medical Tech. Co., Ltd
Coronary Artery Disease
Mainz Registry of Flow-mediated Constriction
The goal of the flow-mediated constriction/ FMC-registry is to investigate whether the measurement of endothelial function using flow-mediated dilation and flow-mediated constriction provides on the presence of coronary…
- Trial name
- NCT01787370
- Where
- Germany
- Volunteers
- 750 people
- Sponsor
- Johannes Gutenberg University Mainz
Coronary Artery Disease, Coronary Stenosis
Transit Time Flow Measurement in Coronary Surgery
Transit-time flowmetry (TTFM) allows grafts quality control during coronary artery bypass surgery by measuring the flow volume through them.
- Conditions
- Coronary Artery Disease, Coronary Stenosis, Coronary Bypass Graft Stenosis
- Trial name
- COLLATERAL (NCT06471062)
- Where
- Italy
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Coronary Occlusion, Left Main Coronary Artery Disease
ANGiographic Evaluation of Left Main Coronary Artery INtErvention
To assess if an angiographic follow-up at 6 months after Percutaneous Coronary Intervention in Left Main Coronary Artery Disease decrease the composite objective of death, myocardial infarction, and stroke at 36 months.
- Conditions
- Coronary Occlusion, Left Main Coronary Artery Disease, Coronary Artery Stenosis, Coronary Disease
- Trial name
- ANGELINE (NCT04604197)
- Testing
- Angiography and Clinical Follow up, Clinical Follow up
- Where
- 30 sites in Spain
- Volunteers
- 400 people
- Sponsor
- Fundación EPIC
Ischemic Heart Disease, Coronary Artery Stenosis
AI-Enhanced Single-Lead ECG Screening for Coronary Stenosis
It is a prospective, controlled, single-center, non-randomized, observational study. Two patient groups are planned for inclusion: the first - 200 patients with significant coronary artery stenosis confirmed by coronary…
- Conditions
- Ischemic Heart Disease, Coronary Artery Stenosis, Stable Angina Pectoris, Acute Coronary Syndromes
- Trial name
- NCT07579624
- Testing
- single-channel electrocardiogram
- Where
- Russia
- Volunteers
- 400 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Coronary Artery Stenosis
Anatomical Assessment Versus Pull Back RFR Measurement
The READY register is a multicenter open label registry of patients underwent invasive intracoronary FFR and RFR measurement using the Quantien system.
- Trial name
- READY (NCT04857762)
- Where
- 6 sites in Austria, Hungary
- Volunteers
- 500 people
- Sponsor
- Szabolcs - Szatmár - Bereg County Hospitals and University Teaching Hospital, András Jósa Teaching H
Hypertrophic Cardiomyopathy, Coronary Artery Disease
Hypertrophic Cardiomyopathy Pilot Study
This study evaluates mechanisms of arrhythmogenicity in hypertrophic cardiomyopathy, in comparison to patients with well-understood arrhythmogenic substrate (ischemic cardiomyopathy), as well as to individuals free from…
- Trial name
- NCT02806479
- Testing
- Observational: Arrhythmogenic Substrate
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Oregon Health and Science University
Cognitive Function, Stenosis
Clinical Registration Study of Patients With Intracranial / Carotid Stenosis
Through prospective registration and follow-up, this study will collect data of patients with intracranial/carotid stenosis, including clinical information, neuropsychological scales, multimodal magnetic resonance images.
- Trial name
- NCT05322824
- Testing
- standard medical treatment, Interventional stenting
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Peripheral Arterial Disease, Femoropopliteal Stenosis
PMCF Study for Peripheral Arteries Above the Knee (ATK)
The rationale of this study is to confirm and support the clinical safety and performance of the products in a real-word population of 350 patients who underwent an endovascular intervention within standard-of-care (SOC) of the…
- Conditions
- Peripheral Arterial Disease, Femoropopliteal Stenosis, Angiopathy, Peripheral
- Trial name
- NCT05312580
- Where
- 9 sites in Austria, France and 1 more
- Volunteers
- 387 people
- Sponsor
- Cordis US Corp.
Acute Coronary Syndrome With ST Elevation on Electrocardiogram, Acute Coronary Syndrome Without ST Elevation on Electrocardiogram
Tryptase and Coronary Heart Disease
The main aim of this study will evaluate differences in serum levels of tryptase in study population. Will be selected a number of 350 patients hospitalized for coronary heart disease.
- Conditions
- Acute Coronary Syndrome With ST Elevation on Electrocardiogram, Acute Coronary Syndrome Without ST Elevation on Electrocardiogram, Noncritical Coronary Artery Disease Coronary Stenosis Less Than 50 Per Cent, Aortic Aneurysms
- Trial name
- NCT01618279
- Where
- Italy
- Volunteers
- 350 people
- Sponsor
- Niguarda Hospital
Valvular Disease, Valvular Heart Disease
Epidemiology and Long-term Outcome of Patients With VHD
Valvular heart diseases are significant problem in Polish population. Coexistence of coronary artery disease in patients with VHD increases the risk of death and affects further therapeutic strategy.
- Conditions
- Valvular Disease, Valvular Heart Disease, Aortic Valve Stenosis, Mitral Insufficiency and Aortic Stenosis
- Trial name
- BIA-WAD (NCT04527367)
- Testing
- Innovative medical technologies in invasive cardiology and cardiac surgery
- Where
- Poland
- Volunteers
- 2,500 people
- Sponsor
- Medical University of Bialystok
Coronary Artery Disease, Coronary Stenosis
Contrast Enhancement on Coronary Computed Tomographic Angiography
Computed tomographic angiography (CTA) is an important prognostic tool with regard to the detection of coronary artery stenoses.
- Trial name
- EICAR (NCT02462044)
- Testing
- 240 mg Iodine, 300 mg Iodine, 370 mg Iodine
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Maastricht University Medical Center
Aortic Stenosis, Aortic Sclerosis
Risk Factors Associated With Calcification of the Aortic Valve
The purpose of this study is to determine the degree of endothelial dysfunction and inflammation in calcific aortic valve disease associated with coronary artery disease(CAD).
- Trial name
- NCT00375336
- Where
- Czechia
- Volunteers
- 300 people
- Sponsor
- Charles University, Czech Republic
Solid Malignancy Located in the Head and Neck, Cancer
Study of 68GaNOTA-Anti-MMR-VHH2 in Oncological Lesions, Cardiovascular Atherosclerosis, Syndrome With Abnormal Immune Activation and sarcoïdosis
Phase II study to evaluate the clinical potential of 68GaNOTA-anti-MMR-VHH2 for in vivo imaging of Macrophage Mannose Receptor (MMR)-expressing Macrophages by means of Positron Emission Tomography (PET) in patients with…
- Conditions
- Solid Malignancy Located in the Head and Neck, Cancer, Carotid Stenosis, Atherosclerosis of Artery
- Trial name
- MITRAS (NCT04758650)
- Testing
- 68GaNOTA-Anti-MMR-VHH2
- Where
- Belgium
- Volunteers
- 29 people
- Sponsor
- Universitair Ziekenhuis Brussel
Coagulation Disorder, Ischemic Heart Disease
Thrombin Generation Values and Percutaneous Coronary Intervention Results.
Cardiovascular diseases are the most common cause of death in the western world. Myocardial infarction pathogenesis usually involves the development of an atherosclerotic plaque and thrombus.
- Conditions
- Coagulation Disorder, Ischemic Heart Disease, Artery Coronary Stenosis
- Trial name
- NCT03391622
- Testing
- Calibrated Automated Thrombogram
- Where
- Israel
- Volunteers
- 128 people
- Sponsor
- HaEmek Medical Center, Israel
Intracranial Artery Stenosis
Improving Blood Lipid Management in Symptomatic Intracranial Atherosclerotic Stenosis on Clinical Outcome
sICASBLM is a prospective controlled trial, to asses the impact of improving blood lipid management on clinical outcome of moderate to severe symptomatic intracranial atherosclerotic stenosis patients (LDL-C>1.8mmol/L) without…
- Trial name
- sICASBLM (NCT05397405)
- Testing
- PCSK9 inhibitor
- Where
- 2 sites in China
- Volunteers
- 180 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Stable Coronary Artery Disease
Impact of Intensive Exercise Training on Coronary Collateral Circulation in Patients With Stable CAD
Exercise training in patients with coronary artery disease is able to correct several risk factors. Furthermore endothelial function can be improved.
- Trial name
- NCT01209637
- Testing
- exercise training, Intensive exercise training
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- University of Leipzig
Coronary Artery Disease
Diagnostic Accuracy of Quantitative Flow Ratio
The aim of this study was to investigate the accuracy of quantitative flow ratio (QFR) for predicting fractional flow reserve (FFR) ≤0.80 in an independent core laboratory.
- Trial name
- NCT06305572
- Testing
- QFR
- Where
- South Korea
- Volunteers
- 280 people
- Sponsor
- Seoul National University Hospital
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