Clinical trials: Artery Stenosis
Cerebral Artery Stenosis, Carotid Artery Stent
Prediction of Hyperperfusion After Carotid Stenting by Multi-parameter Characteristics Based on Cerebral Autoregulation
Cerebral hyperperfusion syndrome (CHS) is one of the severe complication after carotid artery stenting with a high mortality rate.
- Conditions
- Cerebral Artery Stenosis, Carotid Artery Stent, Dynamic Cerebral Autoregulation
- Trial name
- HACASS (NCT06058676)
- Testing
- carotid artery stenting
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Xuanwu Hospital, Beijing
Coronary Artery Stenosis
Multivessel Disease Diagnosed at the Time of PPCI for STEMI: Complete Revascularization Versus Conservative Strategy.
The aim of the study is to find the optimal management of patients with acute myocardial infarction with ST elevations treated by primary PCI who have at least one significant stenosis of non-culprit coronary artery.
- Trial name
- Prague-13 (NCT01332591)
- Testing
- Percutaneous coronary intervention
- Where
- Czechia
- Volunteers
- 213 people
- Sponsor
- St. Anne's University Hospital Brno, Czech Republic
Aortic Valve Disorder, Aortic Valve Insufficiency
Clinical Trial of the Edwards Aortic Bioprosthesis, Model 11000
The purpose of this observational trial is to gather further clinical data to confirm the safety and performance of the Edwards Pericardial Aortic Bioprosthesis, Model 11000 in this trial population.
- Conditions
- Aortic Valve Disorder, Aortic Valve Insufficiency, Aortic Valve Stenosis, Heart Failure
- Trial name
- NCT01651052
- Testing
- Heart Valve Surgery
- Where
- 2 sites in Poland
- Volunteers
- 133 people
- Sponsor
- Edwards Lifesciences
Blood Pressure Variability, Intracranial Artery Stenosis
Blood Pressure Variability and the Prognosis of Ischemic Stroke With Intracranial Artery Stenosis
Correlation study about Blood Pressure Variability and the prognosis of ischemic stroke with intracranial artery stenosis
- Trial name
- NCT01665235
- Testing
- Amlodipine, ACEI / ARB, Aspirin or Clopidogrel
- Where
- China
- Volunteers
- 200 people
- Sponsor
- RenJi Hospital
Coronary Artery Disease, Coronary Artery Stenosis
First in Man Study of the DREAMS 2nd Generation Drug Eluting Absorbable Metal Scaffold (BIOSOLVE-II)
BIOSOLVE-II is a prospective, international, multicenter, First in Man study. The purpose of this study is to assess the safety and clinical performance of the drug eluting absorbable metal scaffold (DREAMS 2nd Generation).
- Trial name
- BIOSOLVE-II (NCT01960504)
- Testing
- Percutaneous Coronary Intervention (DREAMS) stenting
- Where
- 13 sites in Belgium, Brazil and 6 more
- Volunteers
- 123 people
- Sponsor
- Biotronik AG
Ischemic Heart Disease, Coronary Atherosclerosis
Sirolimus-eluting Stent CALYPSO vs Everolimus-eluting Stent XIENCE
The aim of the study is to evaluate the efficacy and safety of sirolimus-eluting coronary stent "Calypso" (Angioline, Russia) in comparison with everolimus-eluting coronary stent "Xience" (Abbott Vascular, USA)
- Conditions
- Ischemic Heart Disease, Coronary Atherosclerosis, Coronary Artery Disease, Coronary Artery Stenosis
- Trial name
- PATRIOT (NCT02681016)
- Testing
- DES "Calypso", DES "Xience Prime", Coronary angioplasty
- Where
- Russia
- Volunteers
- 610 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Coronary Artery Disease
Hydroxyapatite Active Pro Healing Clinical Trial Program
The purpose of this first feasibility study is to evaluate the performance of Vesta™ \& VestaCOR™ (Hydroxy-Apetite coated GenX) stent in de novo native coronary artery lesions.
- Trial name
- HApFIM (NCT00474084)
- Testing
- Intravascular Coronary Stent
- Volunteers
- 70 people
- Sponsor
- BioSync Scientific Pvt. Ltd.
Coronary Artery Disease, Myocardial Ischemia
AVJ-301 Clinical Trial: A Clinical Evaluation of AVJ-301 (Absorb™ BVS) in Japanese Population
Prospective, Randomized (2:1), active control, single-blind, non-inferiority, multicenter, Japanese Clinical Trial to evaluate the safety and effectiveness of Absorb™ BVS (AVJ-301) in the treatment of subjects with ischemic heart…
- Trial name
- ABSORB JAPAN (NCT01844284)
- Testing
- XIENCE PRIME®/XIENCE Xpedition™, Absorb™ BVS
- Where
- 39 sites in Japan
- Volunteers
- 400 people
- Sponsor
- Abbott Medical Devices
Atherosclerotic Heart Disease With Angina Nos
Effect of Hypercholesterolemia With or Without Hypertension on Coronary Artery Stenosis in Patients With Angina: a Retrospective Study
A multicenter, retrospective clinical study was carried out in the medical records management system of 6 hospitals in Tianjin. Patients who were suffered with Coronary heart disease angina pectoris and underwent coronary…
- Trial name
- NCT04444024
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Tianjin University of Traditional Chinese Medicine
Carotid Artery Stenosis
Evaluation of a Novel Technique to Diagnose Carotid Artery Stenosis
The purpose of this study is to determine the accuracy of a new non-invasive device, the Carotid Stenotic Scan (CSS), to check for stenosis of the internal carotid artery (ICA) as compared to a carotid ultrasound study.
- Trial name
- NCT03464851
- Testing
- Carotid Stenotic Scan (CSS)
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- The Cleveland Clinic
Coronary Artery Disease, Coronary Artery Stenosis
Absorb IV Randomized Controlled Trial
ABSORB IV is a prospective, randomized (1:1, Absorb BVS to XIENCE), single-blind, multi-center study, registering approximately 2610 subjects from approximately 140 sites in the United States and outside the United States.
- Conditions
- Coronary Artery Disease, Coronary Artery Stenosis, Coronary Disease, Coronary Stenosis
- Trial name
- NCT02173379
- Testing
- Absorb BVS, XIENCE
- Where
- 120 sites in United States, Australia and 3 more
- Volunteers
- 2,604 people
- Sponsor
- Abbott Medical Devices
Carotid Stenosis
Cognitive Outcome After Carotid Surgery
The purpose of this study is to understand how carotid endarterectomy (CEA) or percutaneous carotid angioplasty and stenting (CAS) affect memory and thinking resulting in improving or worsening of thinking or memory.
- Trial name
- NCT02118233
- Where
- 3 sites in United States
- Volunteers
- 56 people
- Sponsor
- Lahey Clinic
Coronary Atherosclerosis, Coronary Artery Calcification
Firefighter Aged Garlic Extract Investigation With CoQ10 as a Treatment for Heart Disease (FAITH)
1. Statement of Problem According to the National Fire Protection Association (NFPA), 43.7% of all firefighters that died on the job experienced sudden cardiac death. The job also affords an incredible amount of stress.
- Conditions
- Coronary Atherosclerosis, Coronary Artery Calcification, Coronary Stenosis
- Trial name
- NCT00860847
- Testing
- Aged garlic extract and Coenzyme Q10
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Intracranial Aneurysm, Cerebrovascular Stenosis
Hybrid Operating Treatment of Coexistence of Intracranial Aneurysms and Cerebrovascular Stenosis
To evaluate the clinical benefits and risks of hybrid operating techniques in management of intracranial aneurysms with coexistence of atherosclerotic intracranial arterial stenosis.
- Conditions
- Intracranial Aneurysm, Cerebrovascular Stenosis, Atheroscleroses, Cerebral
- Trial name
- HOT-CIACS (NCT03204435)
- Testing
- Microsurgical aneurysmal operating techniques, endovascular techniques for cerebrovascular stenosis, endovascular techniques for intracranial aneurysms
- Where
- China
- Volunteers
- 196 people
- Sponsor
- liuxingju
Coronary Stenosis, Drug-coated Balloon
Bingo Drug-Coated Balloon in Real World
The purpose is to observe and evaluate the safety and efficacy of Bingo drug-coated balloon in the real world.
- Conditions
- Coronary Stenosis, Drug-coated Balloon, De Novo Stenosis, Coronary Artery Disease in Transplanted Heart Accelerated
- Trial name
- NCT04234893
- Where
- China
- Volunteers
- 805 people
- Sponsor
- Yinyi(Liaoning) Biotech Co., Ltd.
Atherosclerotic Renal Artery Stenosis, Hypertension
Covered vs Bare Metal Stents for Atherosclerotic Renal Artery Stenosis
Atherosclerotic renal artery stenosis is the most common cause of secondary hypertension , increasing the risk of cardiovascular and kidney-related complications.
- Conditions
- Atherosclerotic Renal Artery Stenosis, Hypertension, Renal Artery Stenosis
- Trial name
- COMBAT (NCT07566065)
- Testing
- Covered Stent, Bare Metal Stent
- Where
- 15 sites in China
- Volunteers
- 150 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Coronary Artery Disease, Diagnosis
Evaluating AI-Gatekeeper Software in Coronary Artery Stenosis Screening: A Multicenter RCT
The purpose of this study is to determine the efficacy, safety, and cost-effectiveness of AI-Gatekeeper software to assist clinicians in the diagnosis of coronary artery disease by predicting coronary artery stenosis (≥50%) from…
- Trial name
- AIGatekeeper (NCT06178900)
- Testing
- Assisted by the AI-Gatekeeper software group
- Where
- 5 sites in South Korea
- Volunteers
- 450 people
- Sponsor
- INFINITT Healthcare
Carotid Stenosis, Optical Coherence Tomography (OCT)
Endovascular Treatment of Cerebrovascular Diseases Guided by Optical Coherence Tomography (OCT) Technology（CVD-OCT）
OCT techniques have been used in the assessment of both intracranial and extracranial lesions.(1) Preprocedural evaluation: The morphologic characteristics of carotid atherosclerotic plaques can be evaluated by OCT before surgery…
- Conditions
- Carotid Stenosis, Optical Coherence Tomography (OCT), Endovascular Treatment
- Trial name
- （CVD-OCT) (NCT06986330)
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Cardiovascular Diseases, Myocardial Ischemia
Cohort Study of Heart Rate Variability
To examine factors affecting heart rate variability (HRV) and the role of HRV in heart disease. Specifically, to examine the role of HRV: as a predictor of fatal and nonfatal ischemic heart disease over a six year follow-up of…
- Conditions
- Cardiovascular Diseases, Myocardial Ischemia, Carotid Stenosis, Hypertension
- Trial name
- NCT00005399
- Testing
- No interventions
- Volunteers
- 111,654 people
- Sponsor
- University of North Carolina, Chapel Hill
Coronary Artery Stenosis
Fractional Flow Reserve (FFR) Versus Intravascular Ultrasound (IVUS) in Intermediate Coronary Artery Disease
This study is a prospective, randomized, multi-center, open label trial to compare the clinical outcomes and effectiveness of Intravascular ultrasound (IVUS) versus Fractional Flow Reserve (FFR) guided Percutaneous coronary…
- Trial name
- FAVOR (NCT01175863)
- Testing
- Grey scale intravascular ultrasound (Galaxy or Virtual histology-Intravascular Ultrasound), Pressure wire(Radi Medical Systems)
- Where
- 8 sites in South Korea
- Volunteers
- 1,400 people
- Sponsor
- Ajou University School of Medicine
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