Clinical trials: Arthritis, Degenerative
Osteoarthritis of the Knee
Dose Finding Study of Bone Morphogenetic Protein 7 (BMP-7) in Subjects With Osteoarthritis (OA) of the Knee
The objectives of the study are to evaluate the safety and efficacy of intraarticular BMP-7 for the treatment of osteoarthritis of the knee.
- Trial name
- NCT01111045
- Testing
- Bone morphogenetic protein 7
- Where
- 25 sites in United States
- Volunteers
- 355 people
- Sponsor
- Stryker Biotech
Wrist Osteoarthritis
WristArt Total Wrist Arthroplasty Implant First In Human Study
The WristArt implant will be implanted for the first time in humans' wrists
- Trial name
- NCT06196528
- Testing
- WristArt implant
- Where
- Israel
- Volunteers
- 5 people
- Sponsor
- Fibioseq Medical
Joint Disease, Osteoarthritis
Radiostereometric Analysis (RSA) of the PROFEMUR® Preserve Classic Femoral Components
MicroPort Orthopedics (MPO) is conducting this study to investigate the primary stability of its PROFEMUR® Preserve Femoral Components using radiostereometric analysis (RSA).
- Trial name
- TOPAZ (NCT02668211)
- Testing
- PROFEMUR Preserve Classic Femoral Components
- Where
- Canada
- Sponsor
- MicroPort Orthopedics Inc.
Osteoarthritis
A Study to Assess Etoricoxib Versus Diclofenac in Chinese Patients With Osteoarthritis of the Knee or Hip (0663-080)(COMPLETED)
A Study to Assess Etoricoxib versus Diclofenac in Chinese Patients with Osteoarthritis of the Knee or Hip
- Trial name
- NCT00140972
- Testing
- MK0663; etoricoxib / Duration of Treatment:4 Weeks, Comparator: diclofenac sodium tablet 75 mg / Duration of Treatment:4 Weeks
- Volunteers
- 160 people
- Sponsor
- Organon and Co
Osteoarthritis (OA) of the Knee, Fracture
LinkSymphoKnee (LSK) Total Knee Replacement System Study - Ultra-congruent (UC)
To collect information about implant performance and patient clinical outcomes in patients undergoing primary total knee arthroplasty with the LinkSymphoKnee total knee replacement system with ultra-congruent tibial bearing…
- Conditions
- Osteoarthritis (OA) of the Knee, Fracture, Rheumatoid Arthritis
- Trial name
- NCT06670651
- Testing
- total knee arthroplasty device
- Where
- 2 sites in United States
- Volunteers
- 600 people
- Sponsor
- LinkBio Corp.
Knee Osteoarthritis
Study on Efficacy and Safety of Chondroitin Sulfate + Glucosamine Hydrochloride Versus Celecoxib in Knee Osteoarthritis
The purpose of this study is to determine whether the combination of Chondroitin sulfate (CS) and Glucosamine Hydrochloride (GH) has similar efficacy to Celecoxib (CE) in the treatment of patients with moderate to severe knee…
- Trial name
- MOVES (NCT01425853)
- Testing
- Chondroitin/Glucosamine (Droglican), Celecoxib
- Where
- Spain
- Volunteers
- 606 people
- Sponsor
- Bioiberica
Knee Osteoarthritis
Clinical Trial to Evaluate the Efficacy and Safety of Conjuran® After First and Second Cycle (Repeat) Administration in Patients With Knee Osteoarthritis
This clinical trial aims to evaluate and compare the efficacy and safety of Conjuran® and Hyruan in patients with knee osteoarthritis following first and second cycle (repeat) administration.
- Trial name
- NCT07646483
- Testing
- Conjuran, Hyruan
- Volunteers
- 180 people
- Sponsor
- PharmaResearch Co.,Ltd
Knee Osteoarthritis
Effectiveness and Safety of Intra-articular SEMICAL GEL-B CROSS Therapy in Knee Osteoarthritis (SEM-ART1)
The goal of this clinical trial is to evaluate the effectiveness and safety of intra-articular injection of a cross-linked sodium hyaluronate; SEMICAL GEL-B CROSS, in knee osteoarthritis.
- Trial name
- NCT06141018
- Testing
- Cross-linked intra-articular hyaluronic acid
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Semikal Technology
Osteoarthritis, Knee
Osteoarthritis of the Knee, Inflammation, and the Effect of Adalimumab (OKINADA)
This is a Canadian randomized, double-blind, placebo-controlled, multicenter study designed to evaluate the clinical efficacy and safety of adalimumab versus placebo when used to treat subjects with a diagnosis of osteoarthritis…
- Trial name
- OKINADA (NCT02471118)
- Testing
- Adalimumab 40 mg
- Where
- 7 sites in Canada
- Volunteers
- 62 people
- Sponsor
- CARE ARTHRITIS LTD.
Osteoarthritis
Safety and Biologic Activity Study of Gevokizumab to Treat Erosive Osteoarthritis of the Hand
The purpose of this proof-of-concept study is to determine whether gevokizumab is effective in the treatment of active inflammatory, erosive osteoarthritis of the hand.
- Trial name
- NCT01683396
- Testing
- gevokizumab
- Where
- 27 sites in United States
- Volunteers
- 87 people
- Sponsor
- XOMA (US) LLC
Chronic Pain, Osteoarthritis, Hip
Long Term Safety and Efficacy Study of Tanezumab in Subjects With Osteoarthritis of the Hip or Knee
The purpose of this study is to compare the long-term joint safety and efficacy (pain relief) of the investigational study drug, tanezumab compared to non-steroidal anti inflammatory drugs (NSAIDs) in subjects with osteoarthritis…
- Conditions
- Chronic Pain, Osteoarthritis, Hip, Osteoarthritis, Knee
- Trial name
- NCT02528188
- Testing
- NSAID, Tanezumab 2.5 mg, Tanezumab 5 mg
- Where
- 507 sites in United States, Australia and 16 more
- Volunteers
- 3,021 people
- Sponsor
- Pfizer
Osteoarthritis
ORCA Study: Osteoarthritis and Risks Associated With the Consumption of NSAIDs
Cross-sectional epidemiological study in patients with diagnosis of osteoarthritis (OA) in order to evaluate risk factors associated with the use / prescription of non-steroidal anti-inflammatory drugs (NSAID).
- Trial name
- ORCA (NCT04099459)
- Where
- Colombia
- Volunteers
- 1,250 people
- Sponsor
- Scandinavia Pharma
Osteoarthritis, Rheumatoid Arthritis
Cormet Large Diameter Metal on Metal (LDMOM) Total Hip System (G030265)
To demonstrate the safety and efficacy of the Cormet Large Diameter Metal on Metal (LDMOM) Total Hip System using a composite clinical success (CCS) primary endpoint.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Avascular Necrosis
- Trial name
- NCT00867256
- Testing
- Large Diameter Metal on Metal
- Volunteers
- 195 people
- Sponsor
- Corin
Degenerative Arthritis
Efficacy and Safety Study of TissueGene-C to Degenerative Arthritis
The purpose of this study is to determine whether TissueGene-C, an allogeneic human chondrocytes expressing Transforming Growth Factor(TGF)-b1, is effective and safe in patients with degenerative arthritis.
- Trial name
- NCT02072070
- Testing
- TissueGene-C
- Where
- 12 sites in South Korea
- Volunteers
- 163 people
- Sponsor
- Kolon Life Science
Osteoarthritis
The Safety and Efficacy of XytriX (Umbilical Cord-Derived Mesenchymal Stem Cells) in the Treatment of Knee Osteoarthritis
This study aims to study the safety and efficacy of XytriX, an umbilical cord-derived stem cell product, in the treatment of Grade I-IV knee osteoarthritis.
- Trial name
- NCT07487766
- Testing
- Mesenchymal Stem Cell Injection
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- TricelX Inc.
Pain
An Efficacy and Safety Study of Acetaminophen Plus Tramadol Hydrochloride (JNS013) in Participants With Chronic Pain
The purpose of this study is to evaluate the efficacy and safety of tramadol hydrochloride plus acetaminophen (JNS013) in participants with chronic pain accompanied by osteoarthritis (a progressive and degenerative joint disease…
- Trial name
- NCT00736853
- Testing
- Tramadol Hydrochloride Plus Acetaminophen (Open-Label), Tramadol Hydrochloride Plus Acetaminophen (Double-Blind)
- Where
- 20 sites in Japan
- Volunteers
- 321 people
- Sponsor
- Janssen Pharmaceutical K.K.
Knee Osteoarthristis
ArtiBest for Knee Osteoarthritis
The goal of this clinical trial is to evaluate the real-world effectiveness and safety of ArtiBest in the treatment of knee osteoarthritis. The main questions it aims to answer are: 1.
- Trial name
- NCT06994546
- Testing
- ArtiBest ® Intra articular Injection
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Maxigen Biotech Inc.
Osteoarthritis
Autologous Conditioned Plasma (ACP) Intra-articular (IA) Injections for Knee Osteoarthritis (OA)
This study is primarily investigating the effectiveness of Autologous Conditioned Plasma (ACP) Intra-articular (IA) in patients with Osteoarthritis (OA) in the knee.
- Trial name
- NCT02713542
- Testing
- ACP
- Where
- 4 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Arthrex, Inc.
Osteoarthritis, Rheumatoid Arthritis
A Phase 1 Clinical Trial to Evaluate the Safety and Pharmacokinetic Characteristics of DW1809
Randomized, Open-label, Oral, Single-dose, two-Sequence, four-Period, crossover study
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Back Pain, Acute Upper Respiratory Tract Infection
- Trial name
- NCT05214677
- Testing
- DW1809, DW1809-1
- Where
- South Korea
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Osteoarthritis, Arthritis, Rheumatoid
Assessing the Impact of MOVALIS in Osteoarthritis and Rheumatoid Arthritis Patients on Health Related Quality of Life
The objective of the observational study is to examine the effect of MOVALIS (Meloxicam) therapy on Health Related Quality of Life (HRQoL) in the diverse region of Central and Eastern Europe.
- Trial name
- NCT00619177
- Where
- 319 sites in Croatia, Czechia and 3 more
- Volunteers
- 3,569 people
- Sponsor
- Boehringer Ingelheim
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