Clinical trials: Arthritis, Degenerative
Osteoarthritis
Investigating Medical Research Trends in Osteoarthritis Clinical Trials
Clinical research participation percentages haven't always been fully representative of a given demographic. The goal is to find out which aspects of a clinical trial may make it more difficult for patients to take part or see it…
- Trial name
- NCT05811858
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
Hip Replacement, Primary, Secondary or Post-traumatic Osteoarthrosis
Observational Study to Evaluate Long-Term Outcome in Hip Arthroplasty
This long-term outcomes study is designed to collect safety and efficacy data on designated, commercially available, hip arthroplasty products.
- Conditions
- Hip Replacement, Primary, Secondary or Post-traumatic Osteoarthrosis, Femur Head Necrosis, Congenital Dislocations
- Trial name
- NCT02230826
- Where
- 13 sites in France
- Volunteers
- 2,500 people
- Sponsor
- Corin
Osteoarthritis
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of Multiple Subcutaneous Doses of OLP-1002
This is a Phase 1b, randomised, double-blind, placebo-controlled, parallel study to evaluate the safety, tolerability, pharmacokinetics and preliminary efficacy of multiple SC doses of OLP-1002 in patients who have pain due to…
- Trial name
- NCT04677933
- Testing
- A: OLP-1002, B: OLP-1002
- Where
- 4 sites in Australia
- Volunteers
- 30 people
- Sponsor
- OliPass Australia Pty Ltd
Osteoarthritis
Efficacy and Safety Study of Naproxcinod in Subjects With Osteoarthritis of the Knee
To study of efficacy and safety of Naproxcinod vs. Naproxen and Placebo in the indication of signs and symptoms of osteoarthritis
- Trial name
- NCT00504127
- Testing
- Naproxcinod 375 mg bid, Naproxcinod 750 mg bid, Naproxen 500 mg bid
- Where
- 73 sites in United States
- Volunteers
- 1,020 people
- Sponsor
- NicOx
Age-Related Macular Degeneration, Allergies
Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives
To collect, preserve, and/or distribute annotated biospecimens and associated medical data to institutionally approved, investigator-directed biomedical research to discover and develop new treatments, diagnostics, and…
- Conditions
- Age-Related Macular Degeneration, Allergies, Alpha-Gal Syndrome, Alzheimer Disease
- Trial name
- NCT05635266
- Testing
- Specimen sample
- Where
- United States
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Sanguine Biosciences
Osteoarthritis
Study to Assess the Efficacy and Safety of Meloxicam vs. Diclofenac SR in Patients With Osteoarthritis of the Knee
To assess the efficacy and safety of meloxicam 7.5mg once daily compared with diclofenac 100mg SR once daily over a treatment period of 8 weeks
- Trial name
- NCT02183129
- Testing
- Diclofenac, Meloxicam
- Volunteers
- 91 people
- Sponsor
- Boehringer Ingelheim
Osteoarthritis of the Knee
Safety and Efficacy of Two Dosages of Diractin® in Osteoarthritis (OA)
The purpose of this study is to provide replicated evidence of safety and efficacy of 50 mg and 100 mg ketoprofen in Diractin®.
- Trial name
- NCT00716547
- Testing
- ketoprofen in Diractin®, celecoxib
- Where
- 4 sites in Czechia, Germany and 2 more
- Volunteers
- 1,399 people
- Sponsor
- IDEA AG
Osteoarthritis, Hip, Femur Head Necrosis
Prospective Clinical 5-year Follow-up of the LINK® SP-CL® Hip Prosthesis Stem
The objective of this PMCF is to collect clinical and radiographic outcome information on Total Hip Arthroplasty (THA) performed with LINK® SP-CL® Hip Prosthesis Stem under routine conditions.
- Conditions
- Osteoarthritis, Hip, Femur Head Necrosis, Femoral Neck Fractures
- Trial name
- NCT02288117
- Where
- 4 sites in Germany, Italy and 1 more
- Volunteers
- 240 people
- Sponsor
- Waldemar Link GmbH & Co. KG
Osteoarthritis
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Rising Oral Doses of BI 1026706 in Male and Female Healthy Subjects and Patients With Osteoarthritis of the Knee
To investigate the safety and tolerability of BI 1026706 in male and female healthy subjects and osteoarthritis (OA) patients following oral administration of repeated rising doses To explore the pharmacokinetics after multiple…
- Trial name
- NCT02126826
- Testing
- BI 1026706
- Where
- Germany
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Mild to Moderate Knee OA
A Prospective Observational Study to Evaluate Long-term Changes in Cartilage Morphology in Subjects Who Previously Received TPX-100 or Placebo in Study TPX-100-1 for Patellar Osteoarthritis Involving Both Knees
To evaluate the long-term changes in patellar cartilage thickness in TPX-100 versus placebo-treated knees in subjects who participated in Study TPX-100-1 or TPX-100-2.
- Trial name
- NCT03125499
- Testing
- Previous treated with TPX-100
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- OrthoTrophix, Inc
Osteoarthritis, Rheumatoid Arthritis
Descriptive Study in Patients Treated With Vimovo™, Including Registration of the Physicians' Prescribing Patterns
The most common pain-relievers used by patients with rheumatic disorders are called non-steroidal anti-inflammatory drugs (NSAIDs).
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Ankylosing Spondylitis
- Trial name
- CHARACTERIZE (NCT01511926)
- Where
- 96 sites in Belgium, Finland and 6 more
- Volunteers
- 2,000 people
- Sponsor
- AstraZeneca
Bone Necrosis, Arthritis/Arthrosis
Prospective Clinical 5-year Follow-up of the LINK® Endo-Model® SL®
The objective of this study is to collect outcome information on patients requiring Total Knee Replacement (TKR) in primary or revision cases and therefore receiving the LINK® Endo-Model® SL® under routine conditions.
- Conditions
- Bone Necrosis, Arthritis/Arthrosis, Failure of Prosthetic Joint Implant
- Trial name
- NCT02367417
- Where
- 3 sites in Germany
- Volunteers
- 61 people
- Sponsor
- Waldemar Link GmbH & Co. KG
Osteoarthritis of the Hip
Low Level Magnetic Fields for the Treatment of Osteoarthritis of the Hip
The purpose of this study is to see if using a device called the Resonator, that puts out very low level electromagnetic fields will help symptoms of painful hip(s)
- Trial name
- NCT01312285
- Testing
- Resonator device
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- pico-tesla Magnetic Therapies, LLC
Osteoarthritis, Hip, Coxarthrosis; Primary
Osseointegration of THA Grafted by PolyNASS (ACTISURF-CERAFIT® ) Versus Non-grafted THA (CERAFIT®)
The infection rate after Total Hip Arthroplasty (THA) is about 1%. It is a serious condition, with high morbidity, sometimes fatal, requiring costly treatment.
- Conditions
- Osteoarthritis, Hip, Coxarthrosis; Primary, Coxarthrosis; Secondary, Osteonecrosis; Aseptic, Idiopathic
- Trial name
- NCT03113981
- Testing
- Total Hip Arthroplasty
- Where
- 7 sites in France
- Volunteers
- 340 people
- Sponsor
- Societe ACTIVBIOMAT
Osteoarthritis
A Study to Access the Efficacy and Safety of Meloxicam in Patients With Osteoarthritis of the Knee
To Access the Efficacy and Safety of Meloxicam 7.5mg once daily over a treatment period of 56 days
- Trial name
- NCT02183116
- Testing
- Meloxicam
- Volunteers
- 30 people
- Sponsor
- Boehringer Ingelheim
Degenerative Osteoarthritis, Rheumatoid Arthritis
Orthopilot Elite Post-Market Clinical Follow-Up
Prospective, multicenter, observational, comparative clinical trial on the equivalence of two different OrthoPilot® navigation system generations applied for computer-assisted total knee arthroplasty
- Conditions
- Degenerative Osteoarthritis, Rheumatoid Arthritis, Posttraumatic Arthropathy, Instability, Joint
- Trial name
- NCT03817632
- Testing
- Computer assisted primary total knee replacement with OrthoPilot FS101 navigation system and Software 5.1, Computer assisted primary total knee replacement with OrthoPilot Elite navigation system and Software 6.0
- Where
- 3 sites in Germany
- Volunteers
- 217 people
- Sponsor
- Aesculap AG
Osteoarthritis of the Knee
The Study to Evaluate Efficacy and Safety of Imotun Capsule in Osteoarthritis of the Knee
The purpose of this study is to evaluate efficacy and safety of Imotun capsule in osteoarthritis of the knee
- Trial name
- ABSOLUTE-OS (NCT01743287)
- Testing
- Imotun capsule
- Where
- 10 sites in South Korea
- Volunteers
- 234 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Pain, Osteoarthritis, Knee
A Dose-Finding Study to Evaluate the Efficacy and Safety of GSK3858279 in Adults With Knee Osteoarthritis (OA) Pain
This is dose-finding study of GSK3858279 in participants with moderate to severe knee osteoarthritis pain. The purpose of this study is to investigate and provide the data necessary to select the optimal effective and safe…
- Trial name
- MARS-17 (NCT05838742)
- Testing
- GSK3858279
- Where
- 93 sites in United States, Argentina and 11 more
- Volunteers
- 314 people
- Sponsor
- GlaxoSmithKline
Osteoarthritis of the CMC-1 Joint
Clinical Evaluation of the Articulinx InterCarpoMetacarpal Cushion (ICMC) for Osteoarthritis of the First Metacarpal Joint
This study is to evaluate the performance of the Articulinx ICMC (InterCarpoMetacarpalCushion) in the carpometacarpal joint (CMC joint) and to describe the clinical results in patients who have been treated with this device.
- Trial name
- NCT01973803
- Where
- 3 sites in Germany
- Volunteers
- 40 people
- Sponsor
- Articulinx
Total Knee Arthroplasty, Osteoarthritis
A Study to Compare the NexGen LPS and LPS-Flex Knee Implants
The purpose of this study is to test for significant differences in functional outcomes obtained by using a NexGen LPS versus a NexGen LPS-Flex knee implant.
- Trial name
- NCT00763386
- Testing
- NexGen LPS-Flex Fixed Bearing Knee, NexGen Legacy Posterior Stabilized Knee
- Where
- 15 sites in United States, Canada
- Volunteers
- 331 people
- Sponsor
- Zimmer Biomet
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