Clinical trials: Arthritis, Rheumatoid (RA)
Spondyloarthritis (SpA), Psoriatic Arthritis (PsA)
Assessment of Nutritional Status in Rheumatic Diseases and Association to Disease Activity
The aim of the present work is to assess the nutritional status among different rheumatic diseases patients and to study its association with the corresponding diseases activity.
- Conditions
- Spondyloarthritis (SpA), Psoriatic Arthritis (PsA), Systemic Lupus Erythematous (SLE), Systemic Sclerosis (SSc)
- Trial name
- NCT07277491
- Where
- Egypt
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Cairo University
Rheumatoid Arthritis
Observation of Treatment With Certolizumab Pegol in Daily Practice
This is an observational, non-interventional, non-comparative, post-authorization safety study to evaluate efficacy and long-term safety of Cimzia in adult patients with RA in need of treatment with a biological product.
- Trial name
- FasT (NCT01069419)
- Where
- 163 sites in Germany
- Volunteers
- 1,117 people
- Sponsor
- UCB Pharma GmbH
Rheumatoid Arthritis
A Study to Evaluate the Efficacy and Safety of ASP1707 in Postmenopausal Female Patients With Rheumatoid Arthritis Taking Methotrexate
The objective of this study is to evaluate the efficacy, pharmacokinetics, pharmacodynamics and safety of ASP1707 in combination with MTX in postmenopausal female patients with RA.
- Trial name
- NCT02884635
- Testing
- ASP1707, Methotrexate
- Where
- 27 sites in Japan
- Volunteers
- 72 people
- Sponsor
- Astellas Pharma Inc
Arthritis, Rheumatoid
A Study to Validate Questionnaires FLARE and OM-RA-FLARE Measuring Disease Flares in Patients With Rheumatoid Arthritis.
Rheumatoid arthritis (RA) is a rheumatic inflammatory synovitis characterized by pain and joint swelling as well as thickening synovial (pannus) lesions that are responsible of osteocartilaginous and tendon damage.
- Trial name
- FLARE (NCT01722617)
- Testing
- Questionnaire
- Where
- 13 sites in France
- Volunteers
- 207 people
- Sponsor
- Central Hospital, Nancy, France
Rheumatoid Arthritis (RA)
Comparison of Methotrexate (MTX) and the VIBEX™ MTX Device
Relative Bioavailability Comparison study
- Trial name
- NCT01618968
- Testing
- MTX
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Antares Pharma Inc.
Rheumatoid Arthritis, Ankylosing Spondylitis
A Study to Evaluate the Safety of Remsima® SC in the Treatment of RA, AS, PsA and Ps
This is an observational, prospective cohort study to evaluate the safety of Remsima® SC in the treatment of RA, AS, PsA and Ps.
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis, Psoriasis
- Trial name
- NCT05866614
- Testing
- Remsima IV, Remsima SC
- Where
- France
- Volunteers
- 881 people
- Sponsor
- Celltrion
Rheumatoid Arthritis
Etanercept SFP in RA Patients
Purpose of this study is to evaluate the immunogenicity and overall safety of etanercept SFP therapy administered once weekly for 24 weeks to subjects with rheumatoid arthritis.
- Trial name
- NCT00413452
- Testing
- Etanercept
- Volunteers
- 224 people
- Sponsor
- Amgen
Rheumatoid Arthritis
The Chinese University of Hong Kong Early Arthritis Study
The purpose of this study is: 1. To ascertain whether the quantitative assessment of enhancing synovial volume and perfusion indices on serial Magnetic Resonance Imaging (MRI) examination are useful indicators of responsiveness…
- Trial name
- ERA (NCT00901550)
- Testing
- Methotrexate, Infliximab
- Where
- 3 sites in China
- Volunteers
- 40 people
- Sponsor
- Chinese University of Hong Kong
Rheumatoid Arthritis
The Effects of Nutritional on Disease Activity and Functional Status in RA
Rheumatoid arthritis (RA) is a chronic, autoimmune, systemic, inflammatory disease. RA is a chronic inflammatory disease in which many patients cannot achieve remission despite current pharmacological treatments.
- Trial name
- NCT05227885
- Testing
- questionnaire form
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Balikesir University
Rheumatoid Arthritis
Extension Study to Assess the Efficacy and Safety of Repeat Treatment With Rituximab (MabThera) in Participants With Active Rheumatoid Arthritis (RA)
This study will assess the long-term safety and efficacy of repeat treatment courses of rituximab, in combination with methotrexate in a disease-modifying anti-rheumatic drug (DMARD) inadequate responder population of…
- Trial name
- NCT02093026
- Testing
- Rituximab, Methotrexate, Methylprednisolone
- Where
- 92 sites in United States, Australia and 14 more
- Volunteers
- 465 people
- Sponsor
- Hoffmann-La Roche
Rheumatoid Arthritis
Efficacy of Lodotra®(Prednisone) in Reduction of Morning Stiffness Duration(K-IMPROvE)
This study is multicenter, Ph IV, single arm, interventional study to assess relative reduction of morning stiffness of Lodotra® in Rheumatoid Arthritis patients.Study medication will start after study visit at baseline (week 0…
- Trial name
- NCT02072200
- Testing
- Lodotra®
- Where
- South Korea
- Volunteers
- 147 people
- Sponsor
- Mundipharma Korea Ltd
Rheumatoid Arthritis
Trial of a Physical Activity Intervention for RA Fatigue
The major goal of this project is to conduct a randomized, controlled trial of the impact of a practical, low cost physical activity intervention on fatigue among persons with rheumatoid arthritis (RA).
- Trial name
- NCT01874977
- Testing
- Pedometer, Educational materials, Step count goals
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of California, San Francisco
Rheumatoid Arthritis (RA
Investigation Of The Effects Of Anti-Tnf-Α And Non-Tnf-Α Drugs İn Patients With Rheumatoid Arthritis
In RA, joint structure is damaged due to destructive inflammation in the synovium. This condition negatively affects the patient's level of physical activity.
- Trial name
- NCT07182630
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Firat University
Rheumatoid Arthritis
A Pharmacokinetic (PK) and Pharmacodynamic (PD) Study of Golimumab in Patients With Rheumatoid Arthritis (RA)
This is a Phase 1, pharmacokinetic and pharmacodynamic study of intravenous and subcutaneous administered golimumab in patients with rheumatoid arthritis.
- Trial name
- NCT01362153
- Testing
- Golimumab
- Where
- 9 sites in United States
- Volunteers
- 49 people
- Sponsor
- Centocor, Inc.
Rheumatoid Arthritis (RA)
Dietary Factors and Rheumatoid Arthritis Risk in the UK Biobank
Rheumatoid arthritis (RA) is the most common inflammatory arthritis, affecting around 1% of the UK population. It affects around 400,000 adults and is characterised by synovial inflammation, cartilage and bone damage that…
- Trial name
- NCT06670183
- Testing
- Dietary patterns, Food groups and Nutrients, Alcohol intake
- Volunteers
- 500,000 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Rheumatoid Arthritis
Effect of MTX Discontinuation on Shingrix Response in RA
The goal of this clinical trial is to learn if methotrexate discontinuation affect on immunogeneity of shingrix in RA patients. The main questions it aims to answer are: Discontinuation of methotrexate after shingrix immunization…
- Trial name
- NCT06574594
- Testing
- Methotrexate
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- Konkuk University Medical Center
Rheumatoid Arthritis
Infliximab for the Treatment of Early Rheumatoid Arthritis
This study will test whether the drug combination of methotrexate and infliximab (anti-TNF-alpha antibody) is more effective than methotrexate alone for treating rheumatoid arthritis early in the disease.
- Trial name
- NCT00006292
- Testing
- Infliximab
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
RA
To Evaluate Sarilumab - SAR153191 (REGN88) - Auto-injector Device In Patients With Rheumatoid Arthritis
Primary Objective: To collect real-use data of the sarilumab auto-injector device (AID) used by rheumatoid arthritis (RA) participants.
- Trial name
- SARIL-RA-EASY (NCT02057250)
- Testing
- Sarilumab, Auto-Injector Device (AID), Pre-filled Syringe (PFS)
- Where
- 53 sites in United States, Chile and 4 more
- Volunteers
- 217 people
- Sponsor
- Sanofi
Rheumatoid Arthritis
RA-PRO PRAGMATIC TRIAL
The 2021 ACR RA treatment guideline, based on widely acknowledged low to moderate quality evidence, recommends switching to a non-tumor necrosis factor (TNFi) biologic (choose among existing medications, currently, rituximab…
- Trial name
- RA-PROPR (NCT04692493)
- Testing
- targeted synthetic DMARD class, non-TNFi-biologic class
- Where
- 49 sites in United States, Canada
- Volunteers
- 924 people
- Sponsor
- University of Alabama at Birmingham
Rheumatoid Arthritis (RA)
A Study in Rheumatoid Arthritis Patients Who Have Completed a Preceding Study With ABBV-105 Given Alone or in Combination With Upadacitinib
This was a long-term extension (LTE) study to assess the safety, tolerability, and efficacy of ABBV-105 (elsubrutinib [ELS]) and ABBV-599 (ELS 60 mg and upadacitinib [UPA] 15 mg) in participants with rheumatoid arthritis (RA) who…
- Trial name
- NCT03823378
- Testing
- Elsubrutinib, Upadacitinib
- Where
- 30 sites in Belgium, Canada and 5 more
- Volunteers
- 97 people
- Sponsor
- AbbVie