Clinical trials: Arthritis, Unspecified
Rheumatoid Arthritis
Substudy - Low Dose of Abatacept in Subjects With Rheumatoid Arthritis
The purpose of this exploratory sub-study was to evaluate from a clinical perspective the impact on disease activity of lowering the dose of abatacept from 10 mg/kg to 5 mg/kg in subjects who had achieved remission (Disease…
- Trial name
- NCT00989235
- Testing
- Abatacept
- Volunteers
- 108 people
- Sponsor
- Bristol-Myers Squibb
Rheumatoid Arthritis, Ankylosing Spondylitis
Assessment of Treatment Safety and Quality of Life in Patients Receiving Etanercept Biosimilar for Autoimmune Arthritis
In this open-label, multi-center, observational, post-marketing surveillance study, patients with ankylosing spondylitis, psoriatic arthritis, or rheumatoid arthritis received biosimilar etanercept 25 mg twice weekly or 50 mg…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis
- Trial name
- ASQA (NCT04582084)
- Testing
- Etanercept
- Where
- 10 sites in Iran
- Volunteers
- 583 people
- Sponsor
- AryoGen Pharmed Co.
Arthritis, Rheumatoid
Efficacy and Safety of Valdecoxib and Naproxen in Treating the Signs and Symptoms of Rheumatoid Arthritis (RA) in a Severe Rheumatoid Arthritis Patients
The objectives of the study were to evaluate the efficacy, safety, and tolerability of valdecoxib 10 mg once daily (QD) or naproxen 500 mg twice daily (BID) versus placebo, and to assess the efficacy of valdecoxib 10 mg QD versus…
- Trial name
- NCT00650455
- Testing
- valdecoxib, naproxen
- Where
- 55 sites in United States, Canada
- Volunteers
- 489 people
- Sponsor
- Pfizer
Rheumatoid Arthritis, Diabetic Neuropathy
Basket Study (CT-100-002) to Evaluate the Effects of a DiNaMo™ Component Training
CT-100 is a platform that provides interactive, software based therapeutic components that may be used as part of a multimodal treatment in supplementary or standalone prescription or nonprescription software-based digital…
- Conditions
- Rheumatoid Arthritis, Diabetic Neuropathy, Fibromyalgia, Irritable Bowel Syndrome
- Trial name
- NCT05573685
- Testing
- DiNaMo Study App
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Click Therapeutics, Inc.
Knee Osteoarthritis
Follow-up Study for Participants Jointstem Clinical Trial
This study is a long term follow-up study to investigate the safety of autologous transplantation of Adipose Tissue derived Mesenchymal stem cells (MSCs) in patient with Knee Osteoarthritis.
- Trial name
- NCT03509025
- Testing
- Jointstem
- Where
- 2 sites in South Korea
- Volunteers
- 11 people
- Sponsor
- R-Bio
Chronic Pain
Study to Evaluate the Efficacy and Safety of Hydrocodone Bitartrate Extended-Release Tablets (CEP-33237) for Relief of Moderate to Severe Pain in Patients With Osteoarthritis or Low Back Pain Who Require Opioid Treatment for an Extended Period of Time
The primary objective of this study is to evaluate efficacy of hydrocodone extended-release (ER) tablets compared with placebo in alleviating moderate to severe pain in patients with osteoarthritis or low back pain as assessed by…
- Trial name
- NCT01240863
- Testing
- Hydrocodone ER
- Where
- 73 sites in United States
- Volunteers
- 391 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Psoriatic Arthritis
A Study to Evaluate the Efficacy, Safety, and Tolerability of NDI-034858 in Participants With Active Psoriatic Arthritis
This study is designed to evaluate the efficacy, safety, and tolerability of NDI-034858 in participants with active Psoriatic Arthritis (PsA).
- Trial name
- NCT05153148
- Testing
- NDI-034858
- Where
- 56 sites in United States, Czechia and 2 more
- Volunteers
- 305 people
- Sponsor
- Takeda
Osteoarthritis of the Knee
To Compare the Efficacy and Safety of LAYLA in Osteoarthritis Patients of the Knee
This is a randomized, double-blind study to compare the efficacy and safety of LAYLA tablet and CENATONE tablet in the treatment of osteoarthritis of the knee.
- Trial name
- NCT02049606
- Testing
- LAYLA tablet, CENATONE tablet
- Where
- 6 sites in South Korea
- Volunteers
- 134 people
- Sponsor
- PMG Pharm Co., Ltd
Osteoarthritis of the Knee
Total Knee Arthroplasty Functional Outcomes Study Research Design
The purpose of this study is to obtain patient oriented and clinically oriented physical function outcomes both pre-operatively and post-operatively in patients receiving a total knee arthroplasty.
- Trial name
- NCT02228538
- Testing
- Total knee arthroplasty patients
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Restor3D
Rheumatoid Arthritis
A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to Methotrexate
This study will evaluate the safety and efficacy of MabThera in patients with active rheumatoid arthritis who have had an inadequate response or were intolerant to treatment with methotrexate.
- Trial name
- NCT00934648
- Testing
- rituximab [MabThera/Rituxan], methotrexate
- Where
- 5 sites in Morocco
- Volunteers
- 15 people
- Sponsor
- Hoffmann-La Roche
Osteoarthritis of the Knee, Arthroplasty, Replacement, Knee
Flex Intramedullary Rod Study
The purpose of this study is to compare the effect of post-operative ROM between Flex IM rod and Rigid IM rod, to collect bone morphology of Japanese lower extremity and to research the incidence of overhung with Flex IM rod.
- Trial name
- NCT02543489
- Testing
- Flex IM rod
- Where
- 3 sites in Japan
- Volunteers
- 100 people
- Sponsor
- Stryker Japan K.K.
Moderately to Severely Active Rheumatoid Arthritis
A Phase 3 Study to Evaluate Efficacy & Safety of Subcutaneous CT-P13 in Patients With Moderate to Severe Active Rheumatoid Arthritis
This is a Randomized, Placebo-Controlled, Double-Blind, Parallel-Group, Phase 3 Study to Evaluate the Efficacy and Safety of Subcutaneous CT-P13 in Patients with Moderately to Severely Active Rheumatoid Arthritis
- Trial name
- NCT06738719
- Testing
- CT-P13 SC Auto-Injector
- Where
- Poland
- Volunteers
- 192 people
- Sponsor
- Celltrion
Osteoarthritis
A Study to Determine the Difference in Low Contact Stress (LCS) Duofix Versus Low LCS Porocoat Knee Systems
The primary objective of this investigation is to test the hypothesis that the Duofix Tibial component results in a reduction of immediate postoperative pain compared to the LCS Porocoat version.
- Trial name
- NCT00733499
- Testing
- LCS Complete Duofix, LCS Complete Porocoat
- Where
- Ireland
- Volunteers
- 206 people
- Sponsor
- DePuy International
Knee Pain Chronic, Knee Osteoarthritis
The Effects of Home Use of Transcutaneous Electrical Nerve Stimulation on People With Knee OA and or Chronic Knee Pain
The purpose of the research is to see if the use of transcutaneous electrical nerve stimulation (TENS) at home would reduce knee pain and swelling in people with knee OA and/or chronic knee pain.
- Trial name
- NCT05062499
- Testing
- Active TENS
- Volunteers
- 60 people
- Sponsor
- Omron Healthcare Co., Ltd.
Psoriatic Arthritis
Study to Evaluate Tulisokibart in Adults With Psoriatic Arthritis (MK-7240-015)
Researchers are looking for new ways to treat Psoriatic Arthritis (PsA). This study will help find out if a study medicine called tulisokibart (MK-7240) can treat symptoms of active PsA.
- Trial name
- NCT07486960
- Testing
- Tulisokibart
- Where
- 50 sites in United States, Canada and 6 more
- Volunteers
- 140 people
- Sponsor
- Merck Sharp & Dohme LLC
Rheumatoid Arthritis
A Study to Assess the Effect of Tocilizumab on Signs and Symptoms in Patients With Rheumatoid Arthritis
This single arm, open label study will assess the safety and efficacy, with regard to reduction of signs and symptoms,of treatment with tocilizumab in patients with moderate to severe active rheumatoid arthritis.
- Trial name
- NCT00848120
- Testing
- tocilizumab [RoActemra/Actemra]
- Where
- 4 sites in Philippines
- Volunteers
- 29 people
- Sponsor
- Hoffmann-La Roche
Bioavailability of ASP015K, Pharmacokinetics of ASP015K
A Single Oral Dose Study of ASP015K in Healthy Volunteers Assessing the Relative Bioavailability Across Three Tablet Strengths From a New Formulation of ASP015K
The purpose of this study is to determine the relative bioavailability and pharmacokinetic profiles from three strengths of a new tablet formulation of ASP015K and to evaluate the safety and tolerability after a single dose of…
- Conditions
- Bioavailability of ASP015K, Pharmacokinetics of ASP015K, Healthy Subjects
- Trial name
- NCT01486017
- Testing
- ASP015K
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Knee Osteoarthritis
X-Ray Study Investigating The Safety And Efficacy Of SD-6010 In Subjects With Osteoarthritis Of The Knee
The objective of this 2-year study is to evaluate the safety, tolerability and disease modifying efficacy of SD 6010, an inhibitor of inducible nitric oxide synthase (iNOS).
- Trial name
- NCT01438918
- Testing
- SD-6010
- Sponsor
- Pfizer
Rheumatoid Arthritis
A Study in Participants With Moderate to Severe Rheumatoid Arthritis
The purpose of this study is to determine whether baricitinib therapy alone is noninferior to methotrexate (MTX) therapy alone in the treatment of moderate to severe active rheumatoid arthritis (RA) in those who have had limited…
- Trial name
- RA-BEGIN (NCT01711359)
- Testing
- Baricitinib, Methotrexate, Folic Acid
- Where
- 154 sites in United States, Argentina and 17 more
- Volunteers
- 588 people
- Sponsor
- Eli Lilly and Company
Osteoarthritis
A Study of MK0663 and an Approved Drug in the Treatment of Osteoarthritis (0663-076)(COMPLETED)
The purpose of this study is to compare the safety and effectiveness of an investigational drug and an approved drug in the treatment of osteoarthritis of the knee and hip.
- Trial name
- NCT00092768
- Testing
- MK0663, etoricoxib, Comparator: celecoxib
- Volunteers
- 500 people
- Sponsor
- Organon and Co
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