Clinical trials: Arthritis, Unspecified
Osteoarthritis
Viscosupplementation in the Hip Following Hip Arthroscopy
Hip arthroscopy is a rapidly evolving procedure that has seen an exponential increase in the number of cases performed yearly. With hip arthroscopy still in its infancy in relation to knee and shoulder arthroscopy, there are…
- Trial name
- NCT02476903
- Testing
- Monovisc
- Sponsor
- Rothman Institute Orthopaedics
Rheumatoid Arthritis
A Study to Evaluate the Long-Term Safety and Efficacy of GDC-0853 in Participants With Moderate to Severe Rheumatoid Arthritis Enrolled in Study GA29350
A study to evaluate the long-term safety and efficacy of GDC-0853 in participants with moderate to severe active Rheumatoid Arthritis (RA) who have completed 12 weeks of study treatment in Study GA29350.
- Trial name
- NCT02983227
- Testing
- GDC-0853
- Where
- 104 sites in United States, Argentina and 8 more
- Volunteers
- 496 people
- Sponsor
- Genentech, Inc.
Knee Osteoarthritis
Evaluation of the Efficiency of Propioceptive Study According to Radiological Stages in Patients With Knee Osteoarthritis
Evaluation of the Efficiency of Propioceptive Study According to Radiological Stages in Patients with Knee Osteoarthritis
- Trial name
- NCT06150170
- Testing
- Proprioceptive training
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Istanbul University
Gout, Renal Insufficiency
Optimal Administration of Allopurinol in Dialysis Patients
Gout has a strong association with the metabolic syndrome, and it is often seen in patients with renal insufficiency. Allopurinol is a medication intended to lower uric acid and therefore prevents gout attacks.
- Trial name
- NCT02477488
- Testing
- Allopurinol
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Chikungunya, Arthritis
Chikungunya Arthritis in the Americas
Chikungunya is a mosquito-borne viral illness that leads to chronic joint pain in approximately one half of patients. The mechanisms leading to long term arthritis in humans has not been well established.
- Trial name
- NCT02463968
- Testing
- Venipuncture for blood draw, Arthrocentesis for synovial fluid draw
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- George Washington University
Anti-CCP Positive Early Rheumatoid Arthritis
Effect Assessment of Periodontal Prophylaxis on Rheumatoid Arthritis Activity.
The purpose of this study is to assess the impact of an intervention (scaled every 06 months associated with the use of mouthwash with essential oils (toothpaste and Listerine® 2 times / day containing polymer Triclosan (Colgate…
- Trial name
- BHYRRA (NCT01706874)
- Testing
- Periodontal prophylaxis
- Where
- France
- Volunteers
- 92 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Knee Osteoarthritis
New Options for Treating Knee Osteoarthritis Pain
This study will be a single-site, four-arm, randomized, placebo-controlled clinical trial. Knee osteoarthritis patients (N=164) will be randomized to Reiki, Sham Reiki (placebo control), mindfulness meditation (active control)…
- Trial name
- NCT05541718
- Testing
- Reiki, Mindfulness Meditation
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- University of Utah
Knee Osteoarthritis
Pain Compared Between the First and the Second Surgery in Staged BTKA
postoperative pain and analgesic consumption between the first and the second surgery would be compared in patients undergoing staged bilateral total knee arthroplasty (BTKA).
- Trial name
- NCT01457313
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Seoul National University Bundang Hospital
Spondylosis, Osteoarthritis
Medial Branch Radiofrequency Ablation and Lumbar Multifidi
The purpose of this study is to evaluate the effects of lumbar medial branch radiofrequency ablation (RFA) on lumbar multifidi muscle size and clinical spinal stability.
- Trial name
- NCT03744260
- Testing
- Patients undergo ultrasound and lumbar MRI
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Columbia University
Exercise, Ankylosing Spondylitis
Clinical Pilates and Aerobic Exercise in Patients With Ankylosing Spondylitis
The aim of our study is to investigate the effect of Clinical Pilates Exercises on functional status and quality of life when applied together with aerobic exercise in patients with ankylosing spondylitis (AS).
- Trial name
- NCT03211559
- Testing
- Exercise
- Where
- Cyprus
- Volunteers
- 36 people
- Sponsor
- Eastern Mediterranean University
SLE (Systemic Lupus), Systemic Sclerosis
Clinical Study on Targeted CD19 or CD19-BCMA CAR-T Therapy for Autoimmune Diseases
This is an open clinical pharmacological translational Research Study, aiming to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics and efficacy of CD19 or CD19-BCMA CAR-T in patients with active SLE, SSc, AAV…
- Conditions
- SLE (Systemic Lupus), Systemic Sclerosis, ANCA Associated Vasculitis, Idiopathic Inflammatory Myopathies
- Trial name
- NCT06548607
- Testing
- CD19 or CD19-BCMA CAR-T
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Nanjing Bioheng Biotech Co., Ltd.
Rheumatoid Arthritis
To Compare the Efficacy and Safety of Low-dose Glucocorticoids and Tofacitinib in Alleviating Moderate to High Disease Activity Rheumatoid Arthritis for 24 Weeks
Glucocorticoids are effective in the treatment of rheumatoid arthritis, but long-term use of glucocorticoids has many side effects. Tofacitinib is a new small-molecule drug targeting JAK, which has been found to act quickly.
- Trial name
- NCT05606107
- Testing
- Tofacitinib, Glucocorticoid
- Where
- 5 sites in China
- Volunteers
- 230 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Calcific Tendinitis of Shoulder
Ultrasound-Guided Extracorporeal Shock Wave Therapy for Calcific Tendinitis
Calcific tendinitis of the shoulder is a debilitating musculoskeletal condition that significantly impacts the working-age population, typically those between 30 and 60 years of age.
- Trial name
- ESWT (NCT07756307)
- Testing
- Ultrasound guide localization, Palpation localization
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Medical University WanFang Hospital
Ankylosing Spondylitis (AS) / Radiographic Axial SpA (r-axSpA)
Biomarkers in Ankylosing Spondylitis
In this study, we aimed to compare serum PGRN(progranulin) and TNF-α levels in AS patients with healthy controls and to determine the relationship between TNF-α inhibitor use and PGRN levels in AS patients.
- Trial name
- NCT07117344
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Arthritis, Rheumatoid
Safety, Efficacy and Pharmacokinetics Study of ALD518 in Patients With Active Rheumatoid Arthritis
The purpose of this study is to determine the safety and efficacy of ALD518 in three different doses in patients who have not had an adequate response to methotrexate.
- Trial name
- ALD518-003 (NCT00867516)
- Testing
- ALD518, Infusion without ALD518'
- Where
- 26 sites in Canada, Georgia and 4 more
- Volunteers
- 127 people
- Sponsor
- CSL Behring
Knee Osteoarthristis
Sleep TO Prevent Post-surgical Pain
This research study is being done to compare different methods of addressing sleep problems before total knee replacement surgery. These methods include Cognitive Behavioral Therapy and light exposure.
- Trial name
- STOPPP (NCT06976138)
- Testing
- Cognitive-Behavioral Therapy for Insomnia, Bright Light therapy via the Re-Timer®, Negative Ion exposure via IonMi Device
- Where
- 2 sites in United States
- Volunteers
- 252 people
- Sponsor
- Johns Hopkins University
Rheumatoid Arthritis
Gonadotropin-Releasing Hormone (GnRH)-Antagonist Therapy in Rheumatoid Arthritis
The purpose of this study is to compare the safety and efficacy of gonadotropin-releasing hormone (GnRH) antagonist therapy versus placebo in patients with moderate to severe rheumatoid arthritis.
- Trial name
- AGRA (NCT00667758)
- Testing
- Cetrorelix
- Where
- Norway
- Volunteers
- 104 people
- Sponsor
- Betanien Hospital
Ankylosing Spondylitis
Study Evaluating Etanercept in Patients With Ankylosing Spondylitis
This study will assess the efficacy of etanercept for the treatment of Ankylosing Spondylitis (AS).
- Trial name
- NCT00458185
- Testing
- etanercept
- Volunteers
- 40 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Rheumatoid Arthritis
Study To Assess The Efficacy And Safety Of Pf-06651600 In Subjects With Rheumatoid Arthritis With An Inadequate Response To Methotrexate
This is an 8 week study to assess the efficacy and safety profile of PF-06651600 in seropositive subjects with rheumatoid arthritis with an inadequate response to methotrexate (up to approximately 50% of subjects may also have…
- Trial name
- NCT02969044
- Testing
- PF-06651600
- Where
- 30 sites in United States, Bulgaria and 7 more
- Volunteers
- 70 people
- Sponsor
- Pfizer
Knee Osteoarthritis
Effects of MWM Vs Sustained Mobilization on Knee Osteoarthritis
This article focused on people diagnosed with grade III Knee OA with sample size of 68 patients , who will randomly divided into two groups .
- Trial name
- MWM (NCT07315464)
- Testing
- mulligan moblization, kaltenborn moblization
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Lahore University of Biological and Applied Sciences
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