Clinical trials: Arthritis, Unspecified
Effect of Manual Lymphatic Drainage on Upper Extremity Functionality in Rheumatoid Arthritis
Manual Lymphatic Drainage for Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a chronic, progressive, autoimmune disease characterized by inflammation of the synovial joints and tendon sheaths. As a result of synovitis, progressive damage occurs in cartilage, bone and joints.
- Trial name
- NCT05529537
- Testing
- manual lymphatic drainage, excersize
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Selcuk University
Rheumatoid Arthritis
Treatment of Arthritis With Syk Kinase Inhibition (TASKI-1)
This is a Phase II, multicenter, randomized, double-blind, placebo-controlled, ascending dose, dose ranging study to evaluate up to three doses of R935788 (50 mg bid, 100 mg bid and 150 mg bid).
- Trial name
- NCT00326339
- Testing
- R788
- Where
- 38 sites in United States, Mexico
- Volunteers
- 189 people
- Sponsor
- Rigel Pharmaceuticals
TMJ Disorder, Ankylosis
Clinical, Microbial and Tissue-based Characterization of Patients Treated for Severe Temporomandibular Joint Pathology
The general objective of this observational study is to clarify the clinical, microbial, and tissue characteristics, aetiology, and risk factors behind severe TMJ pathology.
- Conditions
- TMJ Disorder, Ankylosis, Osteoarthritis
- Trial name
- NCT07350239
- Testing
- open TMJ surgery such as arthroplasty surgery with or without autogen or allogen reconstruction
- Volunteers
- 20 people
- Sponsor
- Örebro University, Sweden
Osteoarthritis, Rheumatoid Arthritis
Effects of Lacosamide on Post-operative Opioid Requirements After a Total Hip Arthroplasty:
The purpose of this study is to determine how effect lacosamide is in reducing the amount of pain medication needed following a total hip arthroplasty.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Avascular Necrosis
- Trial name
- NCT02342977
- Testing
- Lacosamide
- Where
- United States
- Sponsor
- Indiana University
Sacroiliitis, Sacroiliac Joint Dysfunction
Post-Market Clinical Study on a Modular SI Joint Fusion System
A prospective study on the use of the TransLoc 3D SI Joint Fusion System for patients with sacroiliac joint disruptions or degenerative sacroiliitis.
- Trial name
- SPARTAN (NCT05916092)
- Testing
- TransLoc 3D
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- CornerLoc
Systemic Juvenile Idiopathic Arthritis
Study of MRA for Polyarticular Juvenile Idiopathic Arthritis (pJIA)
This is an open-label, Phase III study to evaluate the efficacy, safety and PK of MRA in patients with pJIA.
- Trial name
- NCT00144664
- Testing
- MRA(Tocilizumab)
- Volunteers
- 19 people
- Sponsor
- Chugai Pharmaceutical
Systemic Juvenile Idiopathic Arthritis
Study of Efficacy and Safety of Canakinumab in Japanese Patients With SJIA
This was a phase III study designed to provide efficacy and safety data for canakinumab administered for at least 48 weeks as subcutaneous (s.c.) injection every 4 weeks (q4wk) in Japanese patients with Systemic Juvenile…
- Trial name
- NCT02396212
- Testing
- Canakinumab
- Where
- 7 sites in Japan
- Volunteers
- 19 people
- Sponsor
- Novartis Pharmaceuticals
Osteoarthritis
Geniculate Artery Embolization for Treatment of Osteoarthritis
Single-arm, single-center, no sham or placebo, prospective pilot trial designed to evaluate the feasibility and safety of transcatheter arterial embolization in patients with mild to moderate radiographic knee OA.
- Trial name
- NCT04379700
- Testing
- Transcatheter arterial embolization, Embozene™ Microspheres
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- NYU Langone Health
Rheumatoid Arthritis
Study Evaluating the Clinical and Therapeutic Management of Rheumatoid Arthritis in Spain
This is an epidemiological, multicenter, retrospective study to analyze the management of rheumatoid arthritis (RA) in usual clinical practice in Spain.
- Trial name
- NCT00881881
- Volunteers
- 360 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Arthritis Knee, Pain, Postoperative
Exparel Use in Adductor Canal Block After Total Knee Arthroplasty
Exparel has been shown to have better pain control compared to previously used infiltration agents, including bupivacaine, while having a minor side effect profile.
- Conditions
- Arthritis Knee, Pain, Postoperative, Opioid Use
- Trial name
- NCT04910165
- Testing
- Exparel, Ropivacaine
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- St. Luke's Hospital, Pennsylvania
Ankle Arthritis
The Use of a Dynamic Compression Intramedullary Nail for Tibiotalocalcaneal Arthrodesis
The purpose of this study is to determine the clinical efficacy of a novel dynamic compression intramedullary nail for tibiotalocalcaneal (TTC) arthrodesis.
- Trial name
- NCT02324907
- Testing
- Procedure/Surgery
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Duke University
Psoriatic Arthritis
AMG 827 in Subjects With Psoriatic Arthritis
The study will examine the safety and effectiveness of AMG 827 for the treatment of psoriatic arthritis
- Trial name
- NCT01516957
- Testing
- AMG 827 140, AMG 827 280, AMG 827 210
- Where
- 31 sites in United States, Canada
- Volunteers
- 168 people
- Sponsor
- Bausch Health Americas, Inc.
Arthritis of Knee
ROCC Knee Data Collection
This observational study intends to collect efficacy and safety data on ROCC Knee system.
- Trial name
- NCT00758901
- Testing
- Knee Replacement (with ROCC Knee prosthesis)
- Where
- 3 sites in Austria, France and 1 more
- Volunteers
- 200 people
- Sponsor
- Zimmer Biomet
Arthritis, Rheumatoid, Tocilizumab
Characterization of the Effect of Tocilizumab in Vivo and in Vitro on T Follicular Helper Cells in Rheumatoid Arthritis Patients and Consequence on B Cells Maturation
Naïve CD4+ helper T (Th) cells, upon encountering their cognate antigens presented on professional antigen-presenting cells, differentiate into different effector cells: Th1 cells produce Interferon-γ and regulate antigen…
- Conditions
- Arthritis, Rheumatoid, Tocilizumab, T-Lymphocytes, Helper-Inducer
- Trial name
- Tocihelper (NCT02569736)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Association Aquitaine de Recherche Clinique en Rhumatologie
Osteoarthritis, Knee, Knee Pain Chronic
Impact of Dexamethasone Route on Pain and Inflammation in iPACK With ACB for Knee Arthroplasty
"The Effect of Dexamethasone Administration Route on Pain and Inflammatory Response in iPACK With ACB for Total Knee Arthroplasty" - written in plain language according to ClinicalTrials.gov standards: The goal of this clinical…
- Conditions
- Osteoarthritis, Knee, Knee Pain Chronic, Arthropathy of Knee
- Trial name
- NCT07180953
- Testing
- NaCl 0.9%, Dexamethasone 4mg
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Rheumatoid Arthritis
Umbilical Cord Mesenchymal Stromal Cell Secretome for Moderate Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent synovial inflammation, progressive joint destruction, pain, and functional disability.
- Trial name
- SECRETOME-RA (NCT07715045)
- Testing
- Umbilical Cord-Derived Mesenchymal Stromal Cell (UC-MSC) Secretome
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Universitas Sriwijaya
Arthritis, Rheumatoid, Colitis, Ulcerative
A Study to Learn About the Study Medicine Called Infliximab (Genetical Recombination)[Infliximab Biosimilar 3] in People With Rheumatoid Arthritis, Ulcerative Colitis, Crohn's Disease, or Psoriasis
The purpose of this study is to learn about the safety of the safety of the study medicine called infliximab for the possible treatment of rheumatoid arthritis (RA), ulcerative colitis (UC, Crohn's disease, or psoriasis.
- Conditions
- Arthritis, Rheumatoid, Colitis, Ulcerative, Crohn Disease, Psoriasis
- Trial name
- NCT05796245
- Where
- Japan
- Volunteers
- 2,207 people
- Sponsor
- Pfizer
Acute Gout Arthritis, Acupuncture
Immediate Analgesic Effects of Cheek Acupuncture for Acute Gouty Arthritis
The goal of this clinical trial is to evaluate the immediate analgesic effect and patients' evaluation of the treatment of cheek acupuncture in patients with acute gouty arthritis.
- Conditions
- Acute Gout Arthritis, Acupuncture, Acute Pain
- Trial name
- CAAGA (NCT06001112)
- Testing
- cheek acupuncture, Etoricoxib
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Ankylosing Spondylitis
Interleukin-17 (IL-17) Inhibitor in Combination With Tumor Necrosis Factor α (TNFα )Inhibitor for the Treatment of Ankylosing Spondylitis
The aim of the study is to investigate the efficacy and safety of adalimumab in combination with secukinumab for the treatment of ankylosing spondylitis.
- Trial name
- NCT06833112
- Testing
- Secukinumab, Adalimumab
- Where
- China
- Volunteers
- 10 people
- Sponsor
- The Affiliated Hospital Of Guizhou Medical University
Axial Spondyloarthritis
Efficacy of Golimumab in Early Axial Spondyloarthritis in Relation to Gut Inflammation
The hypothesis of the study is that the presence of (subclinical) gut inflammation at baseline in patients with early active axial spondyloarthritis predisposes to a more severe disease defined as more need to use anti-tumor…
- Trial name
- GO-GUT (NCT03270501)
- Testing
- Golimumab
- Where
- 3 sites in Belgium
- Volunteers
- 64 people
- Sponsor
- University Ghent
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