Clinical trials: Arthritis, Unspecified
Knee Osteoarthritis
Homologus PRP in the Infiltrative Treatment of Knee Osteoarthritis in Young Athletic Patients
The study consists of 3 phases (enrollment, infiltrative procedure, and controls): Identification by specialized orthopedic medical staff belonging to the SC Orthopedic and Trauma Clinic II of the Rizzoli Orthopedic Institute of…
- Trial name
- NCT06483269
- Testing
- PRP infiltration
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto Ortopedico Rizzoli
Rheumatoid Arthritis, Polymyalgia Rheumatica
Prevention of Glucocorticoid-Induced Osteoporosis in Rheumatic Diseases: Alendronate Versus Alfacalcidol.
The purpose of this study is to determine wich treatment is the most effective in prevention of glucocorticoid-induced osteoporosis in patients with rheumatic diseases.
- Conditions
- Rheumatoid Arthritis, Polymyalgia Rheumatica, Giant Cell Arteritis, Polymyositis
- Trial name
- NCT00138983
- Testing
- Alendronate versus alfacalcidol (1-alpha OH vitamin D)
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- UMC Utrecht
Pelvic Pain, Symphysis Pubis Dysfunction
Single Centre Blinded Randomized Controlled Trial Evaluating the Effectiveness of Two Pelvic Support Garments
This blinded randomized comparative trial aims to determine the effectiveness of a customized Dynamic Elastomeric Fabric Orthoses (DEFO) compared to a standard pelvic belt in: a) reducing pregnancy-related pelvic girdle pain…
- Trial name
- MAPS (NCT01820013)
- Testing
- Customised Dynamic Elastomeric fabric Orthoses, Serola Sacroiliac Belt
- Where
- 2 sites in United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Plymouth
Osteoarthritis, Knee, Arthroplasty, Replacement, Knee
Comparative Study of Total Knee Arthroplasty Using a Customized-patient Specific Instrument System.
Patient-specific instrumentation (PSI) has been introduced in total knee arthroplasty (TKA) as a new technology for improving accuracy in restoration of the alignment and biomechanics of the lower limb.
- Trial name
- NCT02500160
- Testing
- Patient specific instrumentation (MRI), Patient specific instrumentation (CT)
- Where
- South Korea
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kyung Hee University Hospital at Gangdong
Osteoarthritis, Total Knee Arthroplasty
Predictability of the Ability to Perform an Emergency Stop
Several studies exist on patient performance in drive simulators especially around and after surgery. Recommendations concerning the ability to drive preoperatively are based on these studies, which generated their data using…
- Trial name
- NCT02175160
- Testing
- Braking and functionality
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Knee Osteoarthritis
Observational Clinical Investigation of Arthrosamid in Knee Osteoarthritis
This is a prospective, long-term, observational, all-comers, open-label, multi-centre clinical investigation enrolling subjects with knee osteoarthritis who is eligible for treatment with Arthrosamid® according to the Instruction…
- Trial name
- LUNA (NCT05057559)
- Where
- 9 sites in Denmark, France and 3 more
- Volunteers
- 201 people
- Sponsor
- Contura
Osteoarthritis (OA) of the Knee
PCL Retention Versus Sacrifice During Total Knee Replacement With a Medial Pivot Prosthesis
otal knee replacement is a common treatment for patients with severe knee osteoarthritis when non-surgical treatments no longer provide adequate relief.
- Trial name
- NCT07849959
- Testing
- PCL Retention During Medial Pivot Total Knee Arthroplasty, PCL Sacrifice During Medial Pivot Total Knee Arthroplasty
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- University of Thessaly
Total Knee Arthroplasty, Knee Osteoarthritis
Patient-navigation-based Preoperative Rehabilitation Exercise Program in Patients Undergoing TKA
This study aimed to assess the effectiveness of a patient navigation-based preoperative rehabilitation exercise program for patients undergoing total knee arthroplasty.
- Trial name
- NCT07047079
- Testing
- Autonomous preoperative rehabilitation exercises, The navigator provided full-period preoperative rehabilitation exercise guidance+navigation services
- Where
- China
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Anna Sun
Rheumatoid Arthritis, Spondyloarthritis
Pregnancy and Medically Assisted Conception in Rare Diseases
Rare diseases frequently affect women of childbearing age. Pregnancy in these women has become less rare, but remains associated with high levels of complications.
- Conditions
- Rheumatoid Arthritis, Spondyloarthritis, Psoriatic Arthritis, Systemic Lupus Erythematosus
- Trial name
- EGR2 (NCT02450396)
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Osteoarthritis, Traumatic Arthritis
The Post-marketing Surveillance to Evaluate the Efficacy of CHONDRON (Autologous Cultured Chondrocyte) by Arthroscopy
A clinical trial to evaluate the long-term efficacy and safety of Chondron (Autologous cultured Chondrocyte) administered through arthroscopy from the drug's 48 weeks efficacy and safety evaluation with 96 weeks follow-up in…
- Trial name
- NCT02539069
- Testing
- Chondron Implantation
- Where
- South Korea
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cellontech Co., Ltd.
Osteoarthritis of the Knee
Proof-of Concept Study of Topical 3%-Diclofenac-Nano-Emulsion Cream for Knee OA Pain
This study valuates the safety and efficacy of treatment with 3% Diclofenac Nano-Emulsion Cream versus Placebo in subjects with osteoarthritis of the knee.
- Trial name
- NCT00484120
- Testing
- 3%-Diclofenac-Nano-Emulsion Cream
- Where
- 4 sites in Israel
- Volunteers
- 123 people
- Sponsor
- Pharmos
Rheumatoid Arthritis
Tocilizumab Effect on microRNA Expression and Adipokine Levels in Rheumatoid Arthritis Patients
The investigators propose to identify changes in cytokines like adipocytokines and microRNA (miR) expression (for example miR-9, miR-16, miR-125, miR-132, miR-146a, miR-150, miR-155, miR-181 and miR-223) in peripheral blood…
- Trial name
- NCT03149796
- Testing
- laboratory blood tests
- Volunteers
- 80 people
- Sponsor
- Carmel Medical Center
Sjögren's Syndrome, Systemic Lupus Erythematosus
Objective Measurement With TCM Pattern for AIDDES
To explore the association with TCM pattern and TCM tongue diagnosis for Autoimmune disease and Dry eye syndrome.
- Conditions
- Sjögren's Syndrome, Systemic Lupus Erythematosus, Dry Eye Syndrome
- Trial name
- NCT04747288
- Testing
- Traditional Chinese Medicine pattern, Traditional Chinese Medicine tongue diagnosis, Heart rate variability
- Where
- Taiwan
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Rheumatoid Arthritis, Carpal Tunnel Syndrome
The Reliability And Validity Of A Smartphone App
The goal of this observational study is to validate a smartphone app called Angulus. The main question it aims to answer is: Is an Angulus App valid and reliable system for masuring hand and wrist range of motion? Participants…
- Trial name
- NCT05819242
- Testing
- Angulus
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Osteoarthritis
Pivotal Study to Evaluate Efficacy and Safety of SP5M002 Inj. as Compared to Synovian Inj. in Patients With Mild to Moderate Knee Osteoarthritis
This is a randomized, double-blind, multicenter, Active Controlled, pivotal clinical trial to assess the efficacy and safety of the novel hexamethylenediamine (HMDA) cross-linked hyaluronate intra-articular injection (SP5M002)…
- Trial name
- NCT06399042
- Testing
- SP5M002 inj, Synovian inj
- Where
- 16 sites in South Korea
- Volunteers
- 297 people
- Sponsor
- Shin Poong Pharmaceutical Co. Ltd.
Active Rheumatoid Arthritis
Clinical Efficacy and Safety of Leflunomide in Egyptian Patients With Active Rheumatoid Arthritis
A Phase IV, Multi-Centric, Prospective, Observational Study to Assess the Clinical Efficacy and Safety of Leflunomide in Egyptian Patients with Active Rheumatoid Arthritis. (CLEAR)
- Trial name
- CLEAR (NCT03599986)
- Where
- Egypt
- Volunteers
- 398 people
- Sponsor
- Eva Pharma
Arthritis, Psoriatic
A Study of the Safety and Effectiveness of Ustekinumab in Patients With Psoriatic Arthritis
The purpose of this study is to evaluate the effectiveness (improvement of signs and symptoms) and safety of ustekinumab in participants with active psoriatic arthritis.
- Trial name
- NCT01009086
- Testing
- Ustekinumab 45 mg, Ustekinumab 90 mg
- Where
- 102 sites in United States, Australia and 12 more
- Volunteers
- 615 people
- Sponsor
- Janssen Research & Development, LLC
Joint Disease
Comprehensive Shoulder System Nano IDE
The purpose of this clinical study is to determine the safety and efficacy of the Comprehensive® Shoulder System with Nano Humeral Component in Total Shoulder Arthroplasty (TSA).
- Trial name
- Nano (NCT01936259)
- Testing
- Mini Stem, Nano
- Where
- 12 sites in United States
- Volunteers
- 258 people
- Sponsor
- Zimmer Biomet
Sjogren's Syndrome, Salivary Gland
Evaluation of Salivary Gland Dysfunction
This study will evaluate patients with complaints of dry mouth to determine the cause and severity of their salivary gland dysfunction and their possible eligibility for other NIDCR protocols.
- Trial name
- NCT00001196
- Where
- United States
- Volunteers
- 1,740 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Osteoarthritis
Hindfoot Alignment in Total Knee Replacement
When carrying out a knee replacement operation one of the goals is to correct any deformity of the leg (bowlegged or knock kneed).
- Trial name
- NCT02583503
- Testing
- Hindfoot alignment view x ray
- Volunteers
- 65 people
- Sponsor
- Golden Jubilee National Hospital
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