Clinical trials: Arthritis, Unspecified
Hip Arthritis
Post Market, Retrospective Study to Evaluate Patients Implanted With Medacta Versafit Cup DM ™️ 2 Years Post-op
This is a post-market, retrospective with one prospective visit, multi- center study, designed to assess the clinical outcomes, surgical details including Anterior or Posterior surgical approach, and collect all complication data…
- Trial name
- NCT03897387
- Where
- 3 sites in United States
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- Medacta USA
Congestive Heart Failure
Exercise-based Cardiac Rehabilitation in Congestive Heart Failure With Coexisting Knee Osteoarthritis
Exercise-based cardiac rehabilitation (CR) has been shown to significantly improve cardiovascular health and overall well-being in patients with congestive heart failure (CHF).
- Trial name
- NCT07440914
- Testing
- Exercise Based Cardiac Rehabilitation, Controlled Group
- Where
- Pakistan
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Axial Spondyloarthritis
Add-on Therapy for Axial Spondyloarthritis
Rationale: Recent investigations suggest that, through certain concentration/meditation techniques, it is possible to modulate autonomic activity.
- Trial name
- NCT02744014
- Testing
- Add-on Therapy for Axial Spondyloarthritis
- Where
- 2 sites in Netherlands
- Volunteers
- 24 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Gonarthrosis; Primary
Efficacy of Ultrasound-Guided Genicular Nerve Block in Patients With Gonarthrosis: A Randomized, Placebo-Controlled, Double-Blind Study
This study planned to enroll a minimum of 30 patients aged 50 years and older, with a diagnosis of gonarthrosis classified as stage 2 or higher according to the Kellgren-Lawrence grading system, and who report complaints of knee…
- Trial name
- NCT07326098
- Testing
- genicular nerve block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ege University
Osteoarthritis, Knee
Knee Osteoarthritis Treatment With Platelet-rich Plasma
Knee osteoarthritis (KOA) is a disease characterized by cartilage degeneration, synovium inflammation, bone remodeling, osteophyte formation, inflammations and loss of articular function.
- Trial name
- NCT05824806
- Testing
- PRP Protocol A, PRP Protocol B, Hyaluronic acid
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- Instituto Nacional de Traumatologia e Ortopedia
Rheumatoid Arthritis
Observational Study to Explore the Effectiveness of Adalimumab Treatment in Conjunction With Utilization of a Patient Support Program (PSP)
This study is a non-confirmatory post-marketing observational study to explore and describe the effectiveness of adalimumab on rheumatoid arthritis (RA) treatment course and participant satisfaction over time in context with…
- Trial name
- PASSION (NCT01383421)
- Volunteers
- 1,036 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Arthritis, Rheumatoid, Spondylitis, Ankylosing
Post Marketing Surveillance Study of Remicade in Patients With Chronic Inflammatory Diseases (P04840)
This study will be performed to evaluate and document the safety and efficacy of infliximab (Remicade®) in the treatment of chronic inflammatory diseases in big cohorts in the daily routine practice of rheumatologists…
- Conditions
- Arthritis, Rheumatoid, Spondylitis, Ankylosing, Arthritis, Psoriatic, Psoriasis
- Trial name
- REMission (NCT00727298)
- Testing
- Infliximab
- Volunteers
- 4,485 people
- Sponsor
- Merck Sharp & Dohme LLC
Osteoarthritis, Knee, Total Knee Replacement
Cooling of the Knee After Total Knee Arthroplasty
This study investigates whether cooling the knee after total knee replacement surgery can reduce pain and improve early recovery.
- Trial name
- NCT07416721
- Testing
- Cool Down Liquid with Bandage ( CoolDown, CH), Ice package cooling system, Standard Postoperative Protocol Without Cooling
- Where
- Serbia
- Volunteers
- 99 people
- Sponsor
- Clinical Center of Vojvodina
Knee Osteoarthritis
Efficacy Study of Pre-emptive Etoricoxib for Postoperative Pain and Functional Outcome in Total Knee Arthroplasty
The purpose of this study is to study the efficacy of pre-emptive etoricoxib in reducing post-operative pain and improving function outcome after a total knee arthroplasty.
- Trial name
- NCT01246362
- Testing
- Control, Etoricoxib
- Where
- Singapore
- Volunteers
- 65 people
- Sponsor
- Singapore General Hospital
Osteoarthritis, Knee
Finnish Unicompartmental and Total Knee Arthroplasty Investigation
Unicondylar knee arthroplasty (UKA) can be used as the treatment of knee OA isolated to a single compartment instead of TKA. Both UKA and TKA have been used for decades as a treatment of knee OA.
- Trial name
- FUNCTION (NCT02481427)
- Testing
- Unicondylar Knee Replacement, Total Knee Replacement
- Where
- 3 sites in Finland
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Rheumatoid Arthritis
Study of LX3305 and Methotrexate in Subjects With Stable Rheumatoid Arthritis
The purpose of the study is to evaluate the effect of LX3305 on methotrexate (MTX) pharmacokinetics and to evaluate the safety and tolerability of LX3305 given over 14 days in subjects with stable rheumatoid arthritis that are…
- Trial name
- NCT00847886
- Testing
- LX3305, Methotrexate
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Lexicon Pharmaceuticals
Osteoarthritis, Hip
Autologous Culture Expanded Adipose Derived MSCs for Treatment of Painful Hip OA
Will injection(s) of autologous culture-expanded AMSCs be safe and efficacious for treatment of painful Hip OA, and if so, which dosing regimen is most effective?
- Trial name
- NCT03608579
- Testing
- Autologous Adipose Derived Mesenchymal Stromal Cells
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Mayo Clinic
Knee OA
a Single HYAJOINT Plus Combined With a Single PPR Versus a Single PRP for Knee OA
Intraarticular hyaluronan or platelet-rich plasma (PRP) is each effective in the treatment for knee osteoarthritis (OA). The efficacy of combined hyaluronan with PRP for knee OA remained unclear.
- Trial name
- NCT04315103
- Testing
- a single intraarticular injection of HYAJOINT Plus (3 ml) followed by 3 ml PRP
- Where
- 2 sites in Taiwan
- Volunteers
- 85 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Osteoarthritis of Knee
Knee Injections for Obese Patients With Knee Arthritis
The purpose of this study is to assess obese patients with knee arthritis and determine the non-inferiority of a low dose steroid treatment vs. standard dose steroid treatment for two knee outcome measures: pain and function.
- Trial name
- NCT06782529
- Testing
- Triamcinolone Acetonide Low Dose, Triamcinolone Acetonide Standard Dose
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Knee Osteoarthritis
Effects of α MAT Versus Steroid Injection in Knee Osteoarthritis (STα MAT-knee Study)
Knee Osteoarthritis (OA) is a common degenerative knee condition of the knee which is treated symptomatically. Knee cartilage tissue has little regenerative ability With the developments in regenerative medicine, stem cells might…
- Trial name
- NCT04230902
- Testing
- Microfragmented Adipose Tissue Transplant, Corticosteroid injection
- Where
- Lebanon
- Volunteers
- 48 people
- Sponsor
- American University of Beirut Medical Center
Knee Osteoarthritis
Biological Response of Stage IV Knee Osteoarthritis to Serial 12.5% Dextrose
Dextrose injection in end-stage knee arthritis will cause growth of cartilage cells in a particular area of complete cartilage loss. Dextrose concentration will be 12.5%.
- Trial name
- NCT01210183
- Testing
- Dextrose intraarticularly administered
- Where
- Argentina
- Volunteers
- 6 people
- Sponsor
- Universidad Nacional de Rosario
Carpometacarpal (CMC) Osteoarthritis
Randomized Placebo Controlled Study of Triamcinolone Acetonide Extended Release Injection for Thumb (CMC) Osteoarthritis
The goal of this study is to investigate if a timed release steroid injection may be beneficial in treating carpometacarpal (CMC) joint (thumb) osteoarthritis. The main questions to be answered are: 1.
- Trial name
- NCT06237153
- Testing
- Triamcinolone Acetonide extended release suspension
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Marie Badalamente
Rheumatoid Arthritis
A Safety Analysis of Oral Prednisone as a Pre-Treatment for Rituximab in Rheumatoid Arthritis.
This study will be an open-label prospective analysis of oral prednisone (compared to IV methylprednisolone) as a pre-treatment for rituximab in patients with rheumatoid arthritis.
- Trial name
- NCT00580229
- Testing
- prednisone
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of South Florida
Periarthritis, Bursitis
Local Injection Under US Control in GTPS.
We hypothesize that local ultrasound guided injection with corticosteroid and local anaesthetic are effective on the symptoms of GTPS.
- Trial name
- NCT01807962
- Testing
- rapidocain and bethametsaone, sterile saline
- Where
- Switzerland
- Volunteers
- 46 people
- Sponsor
- Stephane Genevay
Osteoarthritis, Knee
Effects of Gaseous Cryotherapy on Knee ROM After TKA: A Feasibility Study
A pilot study was performed to investigate the feasibility of a large randomized controlled trial (RCT) to assess the effects of hyperbaric gaseous cryotherapy (HGC) on the change in knee flexion range of motion in the first two…
- Trial name
- NCT02516280
- Testing
- Cryoton ™, Control ice bag
- Volunteers
- 65 people
- Sponsor
- Centre Hospitalier de Verdun
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