Clinical trials: Arthritis, Unspecified
Mild Knee Osteoarthritis, Moderate Knee Osteoarthritis
The Efficacy and Safety Study of 2107 Injection in Subjects With Mild to Moderate Knee Osteoarthritis
This will be a 26-week, prospective, international, multi-center, randomized, active-controlled, double-blinded (to subject and Investigator) study in subjects with mild to moderate OA in the knees to assess safety and efficacy…
- Trial name
- NCT07746843
- Testing
- 2107 Injection, DUROLANE®
- Where
- 3 sites in Poland, Spain and 1 more
- Volunteers
- 286 people
- Sponsor
- BioRegen Biomedical (Changzhou) Co., Ltd
Rheumatoid Arthritis
A Study of Tocilizumab in Combination With DMARDs in Patients With Moderate to Severe Rheumatoid Arthritis
This 2-arm study assessed the safety and efficacy of tocilizumab versus placebo, both in combination with disease modifying antirheumatic drugs (DMARDs), in regard to reduction in signs and symptoms, in patients with moderate to…
- Trial name
- ROSE (NCT00531817)
- Testing
- Tocilizumab, Permitted DMARDs
- Where
- 157 sites in United States, Puerto Rico
- Volunteers
- 619 people
- Sponsor
- Hoffmann-La Roche
Osteoarthritis of the Knee
Cross-over Study of the Efficacy and Safety of SierraSil Joint Formula 14 in Osteoarthritis of the Knee
Osteoarthritis (OA) affects approximately 10% of people older than 60 years, and compromises the quality of life of more than 21 million North Americans.
- Trial name
- 11SOHS (NCT02156440)
- Testing
- SierraSil Joint Formula 14
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- KGK Science Inc.
Rheumatoid Arthritis
Alloimmune Response to Citrullinated Shared Epitope Sequence in Patients With Rheumatoid Arthritis
Rheumatoid arthritis (RA) is an autoimmune and sistemic disease,characterized by joint sinovitis and the production of autoantibodies (Ab).
- Trial name
- ABSEC (NCT03506035)
- Testing
- Research new biomarker for RA
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Corporacion Parc Tauli
Sjogren Syndrome, Sjogren Disease
TREATMENT OF VAGINAL DRYNESS IN SJÖGREN'S DISEASE WITH CO2-LASER VERSUS TOPICAL PROMESTRIENE
Sjögren's disease (SjD) is a chronic, immune-mediated, systemic inflammatory disease characterized mainly by involvement of the salivary and lacrimal glands, causing symptoms of sicca syndrome.
- Conditions
- Sjogren Syndrome, Sjogren Disease, Primary Sjogren Syndrome
- Trial name
- VaLS (NCT07153276)
- Testing
- Fractional CO2 laser (vaginal), Promestriene Vaginal
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo General Hospital
Bioavailability of ASP015K, Pharmacokinetics of ASP015K
A Single Oral Dose Study of ASP015K in Healthy Volunteers Assessing the Relative Bioavailability Across Three Tablet Strengths From a New Formulation of ASP015K
The purpose of this study is to determine the relative bioavailability and pharmacokinetic profiles from three strengths of a new tablet formulation of ASP015K and to evaluate the safety and tolerability after a single dose of…
- Conditions
- Bioavailability of ASP015K, Pharmacokinetics of ASP015K, Healthy Subjects
- Trial name
- NCT01486017
- Testing
- ASP015K
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Arthropathy of Knee Joint
Improving Function After Knee Arthroplasty With Weight-Bearing Biofeedback
The purpose of this study is to determine if rehabilitation using weight-bearing biofeedback training following total knee arthroplasty (TKA) is more effective than standard rehabilitation methods in promoting weight-bearing…
- Trial name
- RELOAD (NCT01333189)
- Testing
- Weight-bearing biofeedback exercise, Standard of care exercise
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Colorado, Denver
Psoriasis (PsO), Psoriatic Arthritis (PsA)
A Clinical Trial of Antiplatelets in Psoriasis
The purpose of this study is to determine the effect of antiplatelet therapy on the endovascular phenotype in psoriasis, specifically whether clopidogrel reduces vascular endothelial pro-atherosclerotic transcript expression more…
- Trial name
- NCT07744191
- Testing
- Aspirin, Clopidogrel
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- NYU Langone Health
Spondyloarthropathies
The Characterization of Small Bowel and Colonic Involvement in Patients With Seronegative Spondyloarthritides
Up to 60% of patients with Seronegative Spondyloarthritides have inflammation in the colon or ileum. This is usually asymptomatic, but in 5 to 10% of patients with SA, Frank IBD will develop.
- Trial name
- SPONDILENDO (NCT00768950)
- Testing
- Capsule endoscopy examination, Colonoscopy
- Where
- Romania
- Volunteers
- 65 people
- Sponsor
- Carol Davila University of Medicine and Pharmacy
Osteoarthritis (OA) of the Knee
Anti-Diabetic Drug, Exercise and Healthy Diet for Knee Osteoarthritis With Overweight/Obesity
Obesity is associated with increased pain with knee osteoarthritis and increase progression of knee osteoarthritis while weight loss intervention has been shown to reduce pain and requirement of total knee replacement.
- Trial name
- ADDED (NCT07065591)
- Testing
- Metformin
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- The University of Hong Kong
Hip Osteoarthritis
Comparative Effects of Focused and Radial Shock-Wave Therapies in Hip Osteoarthritis.
There is no scientific study in the literature regarding the use of shock wave therapy in hip osteoarthritis. In this study, we aim to investigate both the effectiveness of ESWT and which type of ESWT can be more effective in hip…
- Trial name
- NCT05224674
- Testing
- Extracorporeal Shock Wave Therapy (ESWT)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Yuzuncu Yil University
Rheumatoid Arthritis
Puerarin Versus Atorvastatin in Treating Metabolism Syndrome in Patients With Chronic Rheumatic Diseases
To evaluate the Effect of Puerarin tablets versus statins in treating metabolism syndrome in patients with chronic rheumatic diseases
- Trial name
- NCT02219191
- Testing
- puerarin tablet 50 mg, Atorvastatin tablet 20 mg
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Chengdu PLA General Hospital
Ankylosing Spondylitis
Electroacupuncture for Relieving Pain in Ankylosing Spondylitis
Background: Ankylosing spondylitis imposes burdens on individuals and society that AS costs 3 times higher than general population. Conventional approaches for AS have their limitation.
- Trial name
- NCT02697968
- Testing
- Electroacupuncture
- Where
- Hong Kong
- Volunteers
- 20 people
- Sponsor
- The University of Hong Kong
SpA, PsA
Closing the Gap in Care in Seronegative Inflammatory Arthritis
Rheumatologists treating patients with seronegative arthritis will be randomized to treat their patients to a target or to treat their patients under their usual standard of care.
- Trial name
- Metrix II (NCT01749618)
- Testing
- Education and Feedback
- Where
- 9 sites in Canada
- Volunteers
- 40 people
- Sponsor
- Pope Research Corporation
Rheumatoid Arthritis (RA)
Comparison of Methotrexate (MTX) and the VIBEX™ MTX Device
Relative Bioavailability Comparison study
- Trial name
- NCT01618968
- Testing
- MTX
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- Antares Pharma Inc.
Ankylosing Spondylitis
Effects of Aerobic Training in Patients With Ankylosing Spondylitis
This is a randomized controlled trial with blinded assessor on the effects of aerobic exercise (walking)in patients with Ankylosing Spondylitis.
- Trial name
- NCT01586650
- Testing
- aerobic training, Stretching exercises
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Federal University of São Paulo
Knee Osteoarthritis
Assessment of Safety and Efficacy of ARTHRUM 2.5% for Treatment of Painful Osteoarthritis of the Knee
ARTHRUM 2.5% MONO-INJECTION as symptomatic treatment by joint injection extends the conservative therapeutic arsenal in Knee osteoarthritis.
- Trial name
- ART-ONE75 (NCT06228274)
- Testing
- ARTHRUM 2.5%
- Volunteers
- 218 people
- Sponsor
- LCA Pharmaceutical
Osteoarthritis, Osteoarthritis Thumbs
Prospective Clinical Study to Evaluate the Safety and Efficacy of Intraarticular Administration of Micro-grafts of Adipose Tissue (Adipo-micro-grafts) in the Treatment of Osteoarthritis of the Trapezium-metacarpal Joint (ADIPO_MICRO_GRAFTS_1)
The objective of this interventional study is the Change in the Michigan Hand Questionnaire (MHQ) score over time in subjects with Eaton Littler grade II and III trapeziometacarpal osteoarthritis.
- Trial name
- AMG_1 (NCT06997991)
- Testing
- adipose micro-grafts injection
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- Azienda Ospedaliero, Universitaria Ospedali Riuniti
Osteoarthritis, Knee, Rheumatoid Arthritis
Vanguard Rocc Post Market Surveillance
The objective of this project is to obtain prospective, multi-center, long term (10 year) clinical data on the Vanguard Rocc knee prosthesis.
- Conditions
- Osteoarthritis, Knee, Rheumatoid Arthritis, Traumatic Arthritis, Posttraumatic Deformity
- Trial name
- NCT03664791
- Testing
- Vanguard Rocc
- Where
- 9 sites in Belgium, Denmark and 2 more
- Volunteers
- 450 people
- Sponsor
- Zimmer Biomet
Knee Arthropathy, Hip Arthritis
Concepts for Analgosedation During Placement of Regional Anaesthesia Before Operations.
Aim of the study is to specify the best analgosedation technique during placement of regional anaesthesia from the patients' view.
- Conditions
- Knee Arthropathy, Hip Arthritis, Fractures, Closed
- Trial name
- NCT04026074
- Testing
- Fentanyl, Remifentanil, Clonidine
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Graz
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