Clinical trials: Arthritis,Rheumatoid
Rheumatoid Arthritis
The Study of Abatacept in Combination With Etanercept
The Study was designed to look at the safety and efficacy of abatacept in combination with etanercept.
- Trial name
- NCT00162279
- Testing
- Abatacept
- Where
- 35 sites in United States
- Volunteers
- 141 people
- Sponsor
- Bristol-Myers Squibb
Arthritis, Rheumatoid, Colitis, Ulcerative
A Study of Jyseleca Tablet (Filgotinib Maleate) in Korean Participants
The purpose of this study is to collect and evaluate the following information in relation to the safety and the efficacy of Jyseleca tablet (Filgotinib Maleate) 100 milligram (mg) and 200 mg in this post marketing setting: (1)…
- Trial name
- NCT06246123
- Testing
- Non-interventional
- Where
- 59 sites in South Korea
- Volunteers
- 2,040 people
- Sponsor
- Eisai Korea Inc.
Rheumatoid Arthritis
Efficacy and Safety of Olokizumab With Rheumatoid Arthritis With Previously Failed to Anti-tumor Necrosis Factor (Anti-TNF) Therapy
The primary objective of this study is to evaluate the efficacy and safety of CDP6038 administered subcutaneous (sc) at various doses compared to placebo.
- Trial name
- NCT01463059
- Testing
- Olokizumab 60 mg, Olokizumab 120 mg, Olokizumab 240 mg
- Where
- 39 sites in Japan, South Korea and 1 more
- Volunteers
- 119 people
- Sponsor
- UCB Japan Co. Ltd.
Rheumatoid Arthritis
Study of Human Placenta-derived Cells (PDA001) to Evaluate the Safety and Effectiveness for Patients With Active Rheumatoid Arthritis
The primary objective of the study is to assess the safety and efficacy of 2 dose groups (PDA001 versus vehicle control) in subjects with active rheumatoid Arthritis.
- Trial name
- NCT01261403
- Testing
- PDA001
- Where
- 16 sites in United States
- Volunteers
- 26 people
- Sponsor
- Celularity Incorporated
Osteoarthritis, Rheumatoid Arthritis
Cormet Large Diameter Metal on Metal (LDMOM) Total Hip System (G030265)
To demonstrate the safety and efficacy of the Cormet Large Diameter Metal on Metal (LDMOM) Total Hip System using a composite clinical success (CCS) primary endpoint.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Avascular Necrosis
- Trial name
- NCT00867256
- Testing
- Large Diameter Metal on Metal
- Volunteers
- 195 people
- Sponsor
- Corin
Rheumatoid Arthritis
Impact and Use of Abatacept IV for Rheumatoid Arthritis in Real Life Setting
The purpose of this study is to assess Abatacept Intravenous (IV) effectiveness in patients with inadequate response to one or more conventional Disease Modifying Against Rheumatism (DMARDs) including Methotrexate in France…
- Trial name
- ReACTION (NCT02037737)
- Testing
- Abatacept
- Volunteers
- 153 people
- Sponsor
- Bristol-Myers Squibb
Dry Eye
A Study to Assess the Safety and Efficacy of ECF843 vs Vehicle in Subjects With Dry Eye Disease
The study was planned to be conducted in 2 parts: Part 1 to determine the efficacy and safety of ECF843 vs vehicle, followed by Part 2 with additional exploratory assessments of ECF843 vs Vehicle.
- Trial name
- NCT04391894
- Testing
- ECF843, ECF843 vehicle
- Where
- 52 sites in United States
- Volunteers
- 718 people
- Sponsor
- Novartis Pharmaceuticals
Rheumatoid Arthritis
Efficacy and Safety Study of TAS5315 Compared With Placebo in Participants With Rheumatoid Arthritis.
The purpose of this study is to assess the efficacy and safety of TAS5315 in combination with methotrexate in a 12 week or 36 week in participants with rheumatoid arthritis with inadequate response to methotrexate.
- Trial name
- NCT03605251
- Testing
- TAS5315 low dose, TAS5315 high dose
- Where
- Japan
- Volunteers
- 91 people
- Sponsor
- Taiho Pharmaceutical Co., Ltd.
Rheumatoid Arthritis
A Study of Liquid Certolizumab Pegol as Additional Medication to Methotrexate in the Treatment of Signs and Symptoms of Rheumatoid Arthritis and in Prevention of Joint Damage in Patients With Active Rheumatoid Arthritis
A 24 week study in which patients are given study medication and assessed for signs and symptoms of rheumatoid arthritis. X-rays are performed to assess the progress of joint damage during the study.
- Trial name
- NCT00160602
- Testing
- Certolizumab Pegol
- Where
- 70 sites in United States, Bulgaria and 13 more
- Volunteers
- 590 people
- Sponsor
- UCB Pharma
Rheumatoid Diseases, Rheumatoid Arthritis
Post-Marketing Use Of CT-P13 (Infliximab) For Standard Of Care Treatment Of Rheumatoid Diseases Who Are Naïve To Biologics Or Switched From Remicade
To assess persistence of CT-P13 in patients with Rheumatoid Diseases (Rheumatoid arthritis [RA], ankylosing spondylitis [AS], and psoriatic arthritis [PsA]) who are naïve to biologics or are switching from stable Remicade to…
- Conditions
- Rheumatoid Diseases, Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis
- Trial name
- PERSIST (NCT02605642)
- Testing
- CT-P13
- Where
- 38 sites in Bulgaria, Canada and 5 more
- Volunteers
- 351 people
- Sponsor
- Pfizer
Rheumatoid Arthritis
Comparative Pharmacokinetic Study of Three Abatacept Products in Male Normal Healthy Volunteers by the Subcutaneous Route
This is a randomised, double-blind, single dose, parallel groups study to compare the PK, immunogenicity, and safety of 3 abatacept products (DRL_AB, RP and RMP) in male NHV.
- Trial name
- NCT06126042
- Testing
- Test Product, Reference product, Reference Medicinal Product
- Where
- 3 sites in United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Rheumatoid Arthritis
A Retrospective Chart Review of MabThera (Rituximab) Treatment in Rheumatoid Arthritis (RA) Participants in Australia
This is a cross-sectional, observational study examining the factors leading to the therapeutic decision to use MabThera (rituximab) in participants with RA.
- Trial name
- NCT02564770
- Where
- Australia
- Volunteers
- 167 people
- Sponsor
- Hoffmann-La Roche
Rheumatoid Arthritis
Study to Evaluate the Bioequivalence of Pfizer Korea Inc. "XELJANZ 5Mg Tablet" in Healthy Volunteers
This study is an open-label, randomized, fasted, single dose, crossover study to evaluate the bioequivalence of Chong Kun Dang Pharmaceutical "Chong Kun Dang Tofacitinib Tablet" and Pfizer Korea Inc.
- Trial name
- NCT03868072
- Testing
- XELJANZ 5Mg Tablet, Chong Kun Dang Tofacitinib Tablet
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Arthritis, Rheumatoid
INFINITY™ With ADAPTIS™ Technology Study
INFINITY™ with ADAPTIS™ Technology Total Ankle Replacement Follow-up (ITAR2) - Prospective, multi-site, multi-year post-market clinical follow-up study Study Group Primary/Unilateral and/or bilateral Total Ankle Arthroplasty…
- Trial name
- ITAR2 (NCT04594993)
- Testing
- INFINITY™ with ADAPTIS™ Technology Total Ankle System
- Where
- 13 sites in United States
- Volunteers
- 200 people
- Sponsor
- Stryker Trauma and Extremities
Osteoarthritis, Rheumatoid Arthritis
A Phase 1 Clinical Trial to Evaluate the Safety and Pharmacokinetic Characteristics of DW1809
Randomized, Open-label, Oral, Single-dose, two-Sequence, four-Period, crossover study
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Back Pain, Acute Upper Respiratory Tract Infection
- Trial name
- NCT05214677
- Testing
- DW1809, DW1809-1
- Where
- South Korea
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Osteoarthritis, Arthritis, Rheumatoid
Assessing the Impact of MOVALIS in Osteoarthritis and Rheumatoid Arthritis Patients on Health Related Quality of Life
The objective of the observational study is to examine the effect of MOVALIS (Meloxicam) therapy on Health Related Quality of Life (HRQoL) in the diverse region of Central and Eastern Europe.
- Trial name
- NCT00619177
- Where
- 319 sites in Croatia, Czechia and 3 more
- Volunteers
- 3,569 people
- Sponsor
- Boehringer Ingelheim
Rheumatoid Arthritis
An Observational Study of Glucocorticoid Use in Patients With Rheumatoid Arthritis on Treatment With RoActemra/Actemra (Tocilizumab)
This observational study will evaluate the glucocorticoid sparing effect after 12 months of treatment with RoActemra/Actemra (tocilizumab) in patients with rheumatoid arthritis.
- Trial name
- NCT01392001
- Where
- 116 sites in France
- Volunteers
- 322 people
- Sponsor
- Hoffmann-La Roche
Rheumatoid Arthritis (RA)
A Study to Compare Efficacy, Pharmacokinetics, Safety and Immunogenicity of MB04 [Proposed Etanercept Biosimilar] to Enbrel® [EU-sourced] in Rheumatoid Arthritis
A study to compare efficacy, pharmacokinetics, safety and immunogenicity of MB04 [proposed etanercept biosimilar] to Enbrel® [EU-sourced] in rheumatoid arthritis
- Trial name
- NCT06596772
- Testing
- MB04 (proposed biosimilar to etanercept), Enbrel (etanercept)
- Where
- 60 sites in Bulgaria, Georgia and 4 more
- Volunteers
- 501 people
- Sponsor
- mAbxience Research S.L.
Arthritis, Rheumatoid
A Study Comparing Sirukumab (CNTO 136) Monotherapy With Adalimumab (HUMIRA®) Monotherapy in the Treatment of Active Rheumatoid Arthritis
The primary objective is to investigate the efficacy of sirukumab monotherapy compared with adalimumab monotherapy in biologic naïve subjects with active rheumatoid arthritis who are intolerant to methotrexate, who are considered…
- Trial name
- SIRROUND-H (NCT02019472)
- Testing
- adalimumab 40 mg, sirukumab 100 mg, sirukumab 50 mg
- Where
- 107 sites in United States, Bulgaria and 14 more
- Volunteers
- 559 people
- Sponsor
- Janssen Research & Development, LLC
Rheumatoid Arthritis
A Study to Evaluate the Safety and Efficacy of Rituximab in Combination With Methotrexate Compared to Methotrexate Alone in Patients With Active Rheumatoid Arthritis
This study evaluated the efficacy and safety of rituximab in patients with active rheumatoid arthritis (RA).
- Trial name
- SERENE (NCT00299130)
- Testing
- Folate, Methotrexate, Methylprednisolone
- Volunteers
- 511 people
- Sponsor
- Genentech, Inc.
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