Clinical trials: Arthritis (Knee)
Osteoarthritis, Osteo Arthritis Knee
A Study to Assess Efficacy of Supporting Properties and Safety of ARTNEO in Patients With Knee Osteoarthritis
The goal of the interventional study is to assess the effectiveness of the supporting properties and safety of the dietary supplement ARTNEO (ARTNEO®), capsules with an average weight of 585 mg, in patients with osteoarthritis of…
- Conditions
- Osteoarthritis, Osteo Arthritis Knee, Osteoarthritis, Knee
- Trial name
- NCT06032442
- Testing
- ARTNEO, Artra
- Where
- Russia
- Volunteers
- 70 people
- Sponsor
- NPO Petrovax
Osteoarthritis
A Post-Market Retrospective Study on Revision Total Knee Arthroplasty Using Medacta GMK® Revision Prosthesis
This is a retrospective, single-site observational study, designed to assess the clinical outcomes and collect safety data of GMK Revision knee system used for primary or revision total knee arthroplasty at minimum two years…
- Trial name
- NCT02912351
- Testing
- Patient record review, Radiographs, and questionaires.
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medacta USA
Osteoarthritis
A Retrospective Study of the iTotal CR Knee Replacement System
This study involves retrospective collection of data regarding the first approximately 100 iTotal Knee Replacement System surgeries and their short term outcomes at a small set of centers throughout the US.
- Trial name
- NCT01564654
- Testing
- iTotal KRS
- Where
- 4 sites in United States
- Volunteers
- 89 people
- Sponsor
- Restor3D
Osteoarthritis, Knee
Clinical Study to Evaluate Efficacy and Safety of ANT-301 in Patients With Knee Osteoarthritis in Grade III/IV by K/L
This is a phase I open study to evaluate the efficacy and safety of ANT-301 in patients with knee osteoarthritis K\&L Grade III/IV.
- Trial name
- NCT06539429
- Testing
- ANT-301
- Where
- South Korea
- Volunteers
- 6 people
- Sponsor
- Anterogen Co., Ltd.
Knee Osteoarthritis
Effectiveness Study of the Ivivi SofPulse for Pain Amelioration in Adults With Mild to Moderate Knee Osteoarthritis
The purpose of this study is to determine the effectiveness of non-thermal Pulsed Radio Frequency (PRF) treatment with the Ivivi SofPulse for amelioration of knee pain in patients with mild to moderate Osteoarthritis and to…
- Trial name
- NCT01457742
- Testing
- Ivivi SofPulse
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Amp Orthopedics, Inc.
Total Knee Arthroplasty, Knee Disease
Study to Evaluate Long Term Performance and Safety of the Knee Prosthesis (HLS KneeTec Deep Dish)
The aim of this study is to assess the long-term performance and safety of HLS KneeTec Deep Dish knee prosthesis when used in standard medical practice
- Conditions
- Total Knee Arthroplasty, Knee Disease, Total Knee Replacement, Osteo Arthritis Knee
- Trial name
- NCT05211141
- Testing
- HLS KneeTec Deep Dish
- Where
- France
- Volunteers
- 119 people
- Sponsor
- Corin
Osteoarthritis of the Knee
The Study to Evaluate Efficacy and Safety of Imotun Capsule in Osteoarthritis of the Knee
The purpose of this study is to evaluate efficacy and safety of Imotun capsule in osteoarthritis of the knee
- Trial name
- ABSOLUTE-OS (NCT01743287)
- Testing
- Imotun capsule
- Where
- 10 sites in South Korea
- Volunteers
- 234 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Knee Osteoarthritis
To Assess the Efficacy of Collagen Supplement in Osteoarthritis
Collagen Supplement is a natural ingredient that contains undenatured collagen derived from chicken sternum. Collagen Supplement is efficacious and safe as compared to placebo and efficacy is also comparable to glucosamine plus…
- Trial name
- NCT04470336
- Testing
- Collagen Supplement, Glucosamine chondroitin
- Where
- 5 sites in India
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Arthritis, Osteoarthritis
A Comparison of Patients Receiving a Total Knee Replacement With Robotic Assistance or With Conventional Instrumentation
A total knee replacement is the removal of parts of the knee joint, that have become damaged due to osteoarthritis, and replacing these with artificial implants.
- Conditions
- Arthritis, Osteoarthritis, Knee, Joint Diseases
- Trial name
- NCT04976972
- Testing
- NAVIO/CORI Surgical System, Non-robotic conventional instrumentation
- Where
- 10 sites in Ireland, United Kingdom
- Sponsor
- Smith & Nephew Orthopaedics AG
Osteoarthritis, Knee
A Phase 2b/3a Study to Evaluate the Efficacy and Safety of JointStem in Patients Diagnosed as Knee Osteoarthritis
This study is a double-blind, randomized, placebo controlled, multi-center, superiority study to evaluate the efficacy and safety of JointStem, autologous adipose tissue derived mesenchymal stem cells (AdMSC), in patients…
- Trial name
- NCT04368806
- Testing
- JointStem
- Where
- 9 sites in United States, South Korea
- Volunteers
- 173 people
- Sponsor
- Nature Cell Co. Ltd.
Osteoarthritis
BOTOX® Efficacy and Safety in the Treatment of Knee Osteoarthritis
This study will evaluate the efficacy and safety of a single intra-articular injection of 2 doses of BOTOX® (onabotulinumtoxinA) compared with placebo as treatment for knee osteoarthritis symptoms.
- Trial name
- NCT02230956
- Testing
- onabotulinumtoxinA, Normal Saline
- Where
- 3 sites in United States, Czechia and 1 more
- Volunteers
- 176 people
- Sponsor
- Allergan
Knee Osteoarthritis
A Parallel-group Active Comparator, Double-blind, Multicenter, Randomized, Double-blind, Phase III Clinical Study
A multicenter, randomized, double-blind, parallel-group, placebo-controlled, and active-drug, 12-week, multicenter clinical study.
- Trial name
- SAVE (NCT03936192)
- Testing
- glucosamine sulphate 1500mg and meloxicam 15mg, Glucosamine sulfate 1500mg and chondroitin sulfate 1200mg
- Sponsor
- Eurofarma Laboratorios S.A.
Knee Osteoarthritis
Evaluation of Safety and Efficacy of ReHub in Patients Who Underwent Primary Total Knee Arthroplasty
This is a randomized, non-blinded, parallel assignment, clinical trial for the evaluation of safety and efficacy of ReHub, a telerehabilitation system made up of a cloud platform and an exercise kit with smart sensors, for…
- Trial name
- REHAPT (NCT04155957)
- Testing
- Rapid Recovery Rehabilitation Programme, ReHub
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Bio-Sensing Solutions S.L. (DyCare)
Osteoarthritis
Safety, Tolerability and Pharmacokinetics of SAR113945 Following Intra-articular Administration in Patients With Knee Osteoarthritis
Primary Objective: Assess the safety and tolerability of single intra-articular doses of SAR113945 in patients with knee osteoarthritis.
- Trial name
- NCT01113333
- Testing
- SAR113945
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Sanofi
Primary Knee Osteoarthritis Grade 3 - 4
LIKEST Study: Lipocet® in Adults With Primary Knee Osteoarthritis Grade 3-4
The purpose of this study is to assess the safety, tolerability and efficacy of Lipocet® (food supplement) in patients with primary knee osteoarthritis grade 3 - 4
- Trial name
- NCT06134115
- Testing
- Lipocet® (food supplement)
- Where
- 3 sites in Georgia
- Volunteers
- 60 people
- Sponsor
- Pharmanutra S.p.a.
Knee Osteoarthritis, Rheumatoid Arthritis
Freedom® Total Knee System for Treatment of Osteoarthritis, Rheumatoid Arthritis or Post-traumatic Arthritis
A prospective, multi-centre, non-comparative, post-market clinical follow-up study to evaluate the survivorship, safety and performance of the Freedom® Total Knee System in the treatment of approximately 450 subjects who in the…
- Conditions
- Knee Osteoarthritis, Rheumatoid Arthritis, Post-traumatic Osteoarthritis
- Trial name
- Freedom®450 (NCT04033588)
- Testing
- Freedom® Total Knee System
- Volunteers
- 450 people
- Sponsor
- Meril Life Sciences Pvt. Ltd.
Knee Osteoarthritis
Long-Term Follow-up Study of Subjects With Knee Osteoarthritis Who Had Administered FURESTEM-OA Kit Inj. in K0701 Study
Long-Term Follow-up Study of Subjects with Knee Osteoarthritis who had administered FURESTEM-OA Kit Inj. in K0701 study
- Trial name
- NCT06013306
- Volunteers
- 58 people
- Sponsor
- Kang Stem Biotech Co., Ltd.
Osteoarthritis, Knee
Safety Study of a Long-Acting Injectable Steroid to Treat Knee Osteoarthritis
The main purpose of this study is to understand the pharmacokinetics of EP-104IAR and to determine whether it is safe to use in patients with osteoarthritis (OA) of the knee.
- Trial name
- STEPUP (NCT02609126)
- Testing
- EP-104IAR, Vehicle
- Where
- 3 sites in Canada
- Volunteers
- 32 people
- Sponsor
- Eupraxia Pharmaceuticals Inc.
Knee Osteoarthritis
Efficacy and Safety of Glucosamine Sulfate and Chondroitin Sulfate Combination in Treatment of Knee Osteoarthritis
The purpose of this study is to determine whether 500 mg Glucosamine Sulfate / 400 mg Chondroitin Sulfate Capsules and 1500 mg Glucosamine Sulfate / 1200 mg Chondroitin Sulfate Sachet is effective and safe compared Cosamin DS ®…
- Trial name
- NCT02010918
- Testing
- glucosamine sulfate /chondroitin sulfate - capsules, glucosamine sulfate /chondroitin sulfate - sachet, Cosamin DS®
- Where
- Brazil
- Volunteers
- 922 people
- Sponsor
- Ache Laboratorios Farmaceuticos S.A.
Osteoarthritis, Knee
Study to Evaluate the Safety and Efficacy of a Low Level Light Device in Patients With Knee Osteoarthritis
This Phase I study is being conducted to examine the efficacy of the Light Sciences LLC (LSLLC) phototherapy device for home (self) treatment of knee osteoarthritis (OA).
- Trial name
- NCT00375544
- Testing
- Low level light therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Light Sciences LLC
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