Clinical trials: Arthritis Hip
Osteoarthritis, Rheumatoid Arthritis
Anterior Advantage With KINCISE
This is a post-market prospective, 1:1 randomized, multicenter non-inferiority study to compare the femoral broaching time for THA with the Anterior Advantage approach with KINCISE vs. without KINCISE.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Post Traumatic Arthritis
- Trial name
- NCT04191733
- Testing
- KINCISE(TM) Surgical Automated System
- Where
- 11 sites in United States
- Volunteers
- 250 people
- Sponsor
- DePuy Orthopaedics
Arthritis
Aquatic Exercise and Efficacy Enhancement to Decrease Fall Risk in Older Adults With Hip Osteoarthritis
The objective of this project is to determine the effect of aquatic exercise and aquatic exercise combined with an education program on decreasing fall risk in older adults with hip osteoarthritis.
- Trial name
- NCT00289458
- Testing
- exercise, 2, Control
- Where
- Canada
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Osteoarthritis
Pain Expectations in Subjects With Osteoarthritis
The purpose of this research study is to test whether or not researchers can alter or change expectations on pain. The researchers will test whether there is an effect on the size of the pupil and responses to thermal heat…
- Trial name
- NCT02155257
- Testing
- Modafinil, Gabapentin
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Osteoarthritis, Arthritis
Long-Term Analgesic Efficacy And Safety Of Tanezumab Alone Or In Combination With Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Versus NSAIDs Alone In Patients With Osteoarthritis Of The Knee Or Hip
The purpose of this study is to investigate the long-term analgesic efficacy and safety of tanezumab for patients with osteoarthritis (OA) of the knee or hip currently experiencing partial benefit from, and are tolerating…
- Trial name
- NCT00809354
- Testing
- NSAID, tanezumab
- Where
- 333 sites in United States, Canada and 10 more
- Volunteers
- 2,720 people
- Sponsor
- Pfizer
Osteoarthritis, Knee, Osteoarthritis, Hip
Study to Determine the Safety and the Efficacy of Fasinumab Compared to Placebo and Nonsteroidal Anti-inflammatory Drugs (NSAIDs) for Treatment of Adults With Pain From Osteoarthritis of the Knee or Hip
The primary objective of the study is to evaluate the efficacy of fasinumab compared to placebo, when administered for up to 24 weeks in patients with pain due to osteoarthritis (OA) of the knee or hip.
- Trial name
- FACT OA2 (NCT03304379)
- Testing
- Fasinumab, Diclofenac, Celecoxib
- Where
- 71 sites in United States
- Volunteers
- 1,650 people
- Sponsor
- Regeneron Pharmaceuticals
Knee Osteoarthritis, Hip Osteoarthritis
Use of Knotless Suture for Closure of Total Hip and Knee Arthroplasties
Barbed sutures offer several potential advantages in layered wound closure of hip and knee replacement surgeries. It use is gaining increased acceptance across many of the other surgical disciplines at this time.
- Trial name
- NCT00834483
- Testing
- Knotless suture for wound closure, Layered traditional wound closure (monocryl)
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Osteoarthritis, Hip
Mini Stem DEXA (Dual Energy X-ray Absorptiometry)
The objective of this study is to evaluate the bone ingrowth after implantation of the study device. This study will also document any device-related surgical complications or adverse radiographic observations.
- Trial name
- MISDexa (NCT01066936)
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- Smith & Nephew, Inc.
Osteoarthritis
Tanezumab In Osteoarthritis Of The Hip Or Knee
The purpose of the study is to test the efficacy and safety of 2 doses of tanezumab compared to oxycodone CR and placebo in patients with osteoarthritis
- Trial name
- NCT00985621
- Testing
- tanezumab 10 mg, tanezumab 5 mg, oxycodone
- Where
- 112 sites in United States, Austria and 5 more
- Volunteers
- 614 people
- Sponsor
- Pfizer
Arthroplasty, Replacement, Hip
Tritanium® Primary Acetabular Shell Study
This study will be a prospective, non-randomized evaluation of the Tritanium® Acetabular Shell for primary total hip replacement (THR) with a cementless application in a consecutive series of patients who meet the eligibility…
- Trial name
- NCT01063751
- Testing
- Tritanium® Primary Acetabular Shell
- Where
- 7 sites in United States
- Volunteers
- 275 people
- Sponsor
- Stryker Orthopaedics
Osteoarthritis
POLARSTEM Cementless Hip Stem
Multicenter observational study to validate that the POLARSTEM™ is a state-of-the-art implant in terms of radiographic, clinical performance and long-term survivorship.
- Trial name
- POLARSTEM (NCT02648152)
- Testing
- Total Hip Arthroplasty
- Where
- 3 sites in Germany, Switzerland
- Volunteers
- 218 people
- Sponsor
- Smith & Nephew, Inc.
Osteoarthritis, Knee, Osteoarthritis, Hip
Resilience for Older Workers With OA Through Exercise
Exercise is effective at reducing pain while improving physical function. However we do not know if exercise can boost resilience in the workplace, to allow people with osteoarthritis to work as long as they desire.
- Trial name
- NCT02609672
- Testing
- Exercise, No Exercise
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- McMaster University
Osteoarthritis
Extension Study Of Tanezumab In Osteoarthritis
Safety extension study of Phase 3 Osteoarthritis trials with Tanezumab
- Trial name
- NCT00809783
- Testing
- tanezumab
- Where
- 226 sites in United States
- Volunteers
- 2,147 people
- Sponsor
- Pfizer
Osteo Arthritis Knee, Osteoarthritis, Hip
Development of an Osteoarthritis (OA) Care Plan to Improve Process and Quality of OA Treatment Decisions
Knee and hip osteoarthritis (OA) is the most common cause of disability in the U.S. and affects more than 60% of adults over 65 years.
- Trial name
- NCT03102580
- Testing
- OA Care Plan
- Where
- United States
- Volunteers
- 5,713 people
- Sponsor
- University of Massachusetts, Worcester
Knee Osteoarthritis, Hip Osteoarthritis
Mepivacaine Versus Low-Dose Bupivacaine For Primary Total Hip and Knee Arthroplasty
This research is being done to see if there is a difference between two different spinal anesthetics (Mepivacaine vs. Bupivacaine) as it relates to reducing post-operative complications and the time it takes for subjects to…
- Trial name
- NCT03838874
- Testing
- Low-Dose Bupivacaine, Mepivacaine
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- Mayo Clinic
Osteoarthritis, Hip, Osteoarthritis, Knee
A Study Evaluating Pain Relief and Safety of Orally Administered CR845 in Patients With Osteoarthritis of Hip or Knee
The study schedule consists of a Screening Period (up to 14 days), a blinded 4- week Titration-to-Effect Period with weekly visits, a blinded 4-week Maintenance Treatment Period at the optimal dose level determined for each…
- Conditions
- Osteoarthritis, Hip, Osteoarthritis, Knee, Arthritis, Joint Diseases
- Trial name
- NCT02944448
- Testing
- CR845 tablet 1 mg, CR845 tablet 2.5 mg, CR845 tablet 5 mg
- Where
- 35 sites in United States
- Volunteers
- 761 people
- Sponsor
- Cara Therapeutics, Inc.
Surgery, Hip Osteoarthritis
Two Year Study With Robotic-Arm Assisted Hip Surgery.
This study will involve a quantitative assessment of prospectively collected computed tomography, radiographic and patient outcomes data from multiple centers.
- Trial name
- NCT03891199
- Testing
- Robotic-Arm Assisted THA
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Osteoarthritis, Knee, Osteoarthritis, Hip
Increasing Physical Activity in Older Adults With Osteoarthritis Pain: Examining a Brief Behavioral Intervention
The purpose of this study is to evaluate how older adults might benefit from sessions that teach behavioral coping skills for increasing physical activity and reducing interference from arthritis pain.
- Trial name
- NCT04490395
- Testing
- Engage PA, Treatment as Usual plus (TAU+)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Duke University
Pain, Osteoarthritis, Hip
Placebo-controlled Trial With OROS Hydromorphone Hydrochloride to Treat Patients With Moderate to Severe Pain Induced by Osteoarthritis of the Hip or the Knee
This clinical trial tests the pain relieving effectiveness of OROS hydromorphone, a once-daily formulation of a strong opioid against placebo in patients, who are suffering from pain due to osteoarthritis of the hip or the knee…
- Conditions
- Pain, Osteoarthritis, Hip, Osteoarthritis, Knee
- Trial name
- NCT00980798
- Testing
- OROS hydromorphone HCl
- Where
- 12 sites in Czechia, Romania and 2 more
- Volunteers
- 288 people
- Sponsor
- Janssen-Cilag International NV
Hip Arthroplasty, Osteoarthritis
Minimally Invasive Surgery of the Hip Versus Standard Approach
The purpose of this study is to determine if there is a difference in terms of length of hospital stay and post-operative outcomes between patients whose total hip replacement surgery is performed with a minimally invasive versus…
- Trial name
- NCT00261040
- Testing
- Minimally Invasive Surgery, Standard Surgery
- Volunteers
- 40 people
- Sponsor
- Ottawa Hospital Research Institute
Osteoarthritis, Hip
Study to Evaluate a Procedure for Intra-articular Injection of FX006 in Patients With Osteoarthritis of the Hip
This is a multi-center, single-arm, open-label study of FX006 in patients with hip OA. A maximum number of approximately 30 patients may be enrolled in this protocol.
- Trial name
- NCT04065074
- Testing
- FX006 32 mg
- Where
- 5 sites in United States
- Volunteers
- 16 people
- Sponsor
- Pacira Pharmaceuticals, Inc