Clinical trials: Arthritis Knee
Osteoarthritis
A Study to Assess Etoricoxib Versus Diclofenac in Chinese Patients With Osteoarthritis of the Knee or Hip (0663-080)(COMPLETED)
A Study to Assess Etoricoxib versus Diclofenac in Chinese Patients with Osteoarthritis of the Knee or Hip
- Trial name
- NCT00140972
- Testing
- MK0663; etoricoxib / Duration of Treatment:4 Weeks, Comparator: diclofenac sodium tablet 75 mg / Duration of Treatment:4 Weeks
- Volunteers
- 160 people
- Sponsor
- Organon and Co
Knee Osteoarthritis, Arthritis Knee
How Does the Addition of Adductor Canal Block to Local Infiltration Affect Recovery in Patients Undergoing Total Knee Arthroplasty? A Feasibility Study.
The use of periarticular injection and adductor canal block are well-established techniques used both in combination or in isolation in the management of postoperative pain for patients undergoing total knee arthroplasty.
- Conditions
- Knee Osteoarthritis, Arthritis Knee, Knee Disease, Opioid Use
- Trial name
- TRUE KnORTH (NCT04648072)
- Testing
- Adductor Canal Block, Periarticular Injection
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Health Sciences North Research Institute
Knee Osteoarthritis
A Phase 4 Study of Imrecoxib in Treatment of Knee Osteoarthritis
The purpose of this study is to evaluate the efficacy and safety of Imrecoxib in the treatment of patients with knee osteoarthritis.
- Trial name
- NCT01985165
- Testing
- Imrecoxib
- Where
- 19 sites in China
- Volunteers
- 2,400 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Spine Degeneration, Hip Arthritis
Evaluating the Efficacy of a Mobile Application in Postoperative Rehabilitation
This study aims to evaluate the effectiveness of a mobile application in improving postoperative rehabilitation outcomes among patients undergoing orthopedic surgery.
- Conditions
- Spine Degeneration, Hip Arthritis, Knee Osteoarthritis, Hip Fractures
- Trial name
- NCT06407427
- Testing
- App for in-bed conditioning exercises, Usual care
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Yale University
Osteoarthritis, Knee, Hypertension
The Clinical Impact of Diet on Medical Conditions Treated Within Bundled Payment Models: a Pilot Study
Diet interventions (e.g., low-energy diets) are recommended as a treatment for obesity, obese patients with osteoarthritis, hypertension (HTN), and type 2 diabetes (T2D).
- Conditions
- Osteoarthritis, Knee, Hypertension, Type 2 Diabetes, Obesity
- Trial name
- NCT05735873
- Testing
- Low-energy diet
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Osteoarthritis
A Single Time-Point Study to Evaluate the ConforMIS iTotal® (CR) Knee Versus Off-the-Shelf
It has been noted that patients "dramatically overestimate their functional ability early after surgery." Despite use of assistive devices increasing and functional testing scores decreasing post-surgery, the patient reported…
- Trial name
- STEPS (NCT02251522)
- Testing
- ConforMIS Total Knee Replacement System, Off-the-Shelf Knee Replacement System
- Where
- 16 sites in United States, Germany
- Volunteers
- 873 people
- Sponsor
- Restor3D
Osteoarthritis,Knee
Single Adductor-canal-block Versus Peri-articular Infiltration on Outcome After Total Knee Arthroplasty
The purpose of this study is to compare the effect of single adductor-canal-block versus single femoral nerve block on the recovery after total knee arthroplasty.
- Trial name
- NCT02784041
- Testing
- single adductor-canal-block, periarticular infiltration
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Knee Osteoarthritis
Balance Training Using Biodex Stability System in Knee Osteoarthritis.
This was a randomized control Trial, conducted with two group of patients, one has received Balance and stability training on Biodex stability system along with conservative protocol of traditional exercises.
- Trial name
- NCT04019366
- Testing
- Balance Training, Conventional Training
- Where
- Pakistan
- Volunteers
- 43 people
- Sponsor
- Riphah International University
Osteoarthritis, Knee
Study of Safety, Tolerability and Pharmacokinetics of LNA043 in Japanese Osteoarthritis Participants
The objective of this study was to determine the safety, tolerability and pharmacokinetics after single ascending dose of LNA043 in Japanese participants with osteoarthritis of the knee.
- Trial name
- NCT04564053
- Testing
- LNA043
- Where
- 2 sites in Japan
- Volunteers
- 12 people
- Sponsor
- Novartis Pharmaceuticals
Osteoarthritis of the Knee
Comparative Study of Olive Oil With Piroxicam Gel in Osteoarthritis of the Knee
this is a randomized double blinded trial which is conducted to measure the efficacy of topical virgin olive oil on osteoarthritis of knee that will be done in contrast to standard piroxicam gel.
- Trial name
- NCT00670475
- Testing
- Piroxicam, Olive Oil
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Ardabil University of Medical Sciences
Osteo Arthritis Knee
Radiographic Migration Analysis of the ATTUNE Cementless CR Fixed-Bearing Total Knee Replacement
This is a multi-centre, single cohort trial of patients undergoing cruciate-retaining total knee arthroplasty with the Attune Cementless, Fixed Bearing, Cruciate Retaining TKA System.
- Trial name
- NCT06189872
- Testing
- Attune Cementless
- Where
- 3 sites in Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Canadian Radiostereometric Analysis Network
Knee Osteoarthritis, Anatomically Aligned Total Knee Arthroplasty
A Comparison of Anatomically Aligned Versus Conventional in Unilateral Total Knee Arthroplasty
Total knee arthroplasty(TKA) is a successful orthopedic surgery with excellent clinical outcome and survival. However, there are concerns about patient satisfaction in previous reports, and dissatisfaction rate of 15-30% is…
- Trial name
- NCT04181528
- Testing
- Total knee arthroplasty implant
- Volunteers
- 100 people
- Sponsor
- The Catholic University of Korea
Leg Length Inequality, Osteoarthritis, Knee
Shoe Lifts for Leg Length Inequality in Adults With Knee or Hip Symptoms
Limb length inequality is when a person has one leg that is longer than the other. This research will look at correcting limb length inequality in adults with knee or hip symptoms.
- Conditions
- Leg Length Inequality, Osteoarthritis, Knee, Osteoarthritis, Hip
- Trial name
- NCT01894100
- Testing
- Shoe lift correction for leg length inequality
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of North Carolina, Chapel Hill
Knee Osteoarthritis
Mobilization Effect on Hamstring Length
The aim of this research is to determine the effect of knee joint mobilization in patients with knee osteoarthritis having hamstring tightness.
- Trial name
- NCT04574700
- Testing
- knee joint mobilization and traction, Post isometric relaxation
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Knee Osteoarthritis
Bespoke vs Standard Instrumentation in TKR
Total knee replacements are operations that are offered to patients who have severe arthritis pain that is affecting daily activities that is no longer controlled with painkillers.
- Trial name
- SPHERE (NCT05579951)
- Testing
- Patient specific instrumentation, Conventional
- Where
- United Kingdom
- Volunteers
- 172 people
- Sponsor
- Manchester University NHS Foundation Trust
Knee Osteoarthritis
RF TKA Prehabilitation
The purpose of this study is to compare the effects of the radiofrequency applied to the sensory innervation of the knee, with respect to a control group (standard therapy), in a prehabilitation program aiming to improve the…
- Trial name
- NCT03758300
- Testing
- Radiofrequency
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Knee Osteoarthritis
Evaluate Safety and Explore Efficacy of FURESTEM-OA Kit Inj. in Patients With Knee Osteoarthritis
A Single, Dose Escalation, Optimal Dose Finding Phase I/IIa Clinical Trial to Evaluate Safety and Explore Efficacy of the Single Treatment of FURESTEM-OA Kit Inj. in Patients with Knee Osteoarthritis
- Trial name
- NCT05944627
- Testing
- FURESTEM-OA Kit Inj.
- Volunteers
- 68 people
- Sponsor
- Kang Stem Biotech Co., Ltd.
Symptomatic Osteoarthritis of the Knee
Intra-articular Injections for Knee Osteoarthritis: A Single Blinded Prospective Randomized Trial
To investigate the clinical benefit of intra-articular injections of saline in patients with symptomatic osteoarthritis of the knee and compare the clinical response of saline to the current standard treatment with…
- Trial name
- NCT02995083
- Testing
- 40 mg Depo-Medrol in 1 ml, 9 ml of 1% lidocaine, Normal Saline 10 ml, Air 10 ml
- Sponsor
- Rush University Medical Center
Knee Osteoarthritis
Observation of the Clinical Efficacy of Two Surgical Procedures for Varus Knee Osteoarthritis
The purpose of this study is to conduct a prospective randomized controlled trial to compare the effects between two surgical procedures in the treatment of varus knee osteoarthritis.The hypothesis was that there would be no…
- Trial name
- NCT05382429
- Testing
- OWHTO, CWHTO
- Where
- China
- Volunteers
- 160 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Knee Osteoarthritis
Effectiveness of DN With or Without Mulligan Two Leg Rotation Technique on Pain ROM and Joint Dysfunction in KO
The objective of study is to determine the effectiveness of dry needling with or without mulligan two leg rotation technique on pain, range of motion and joint dysfunction in knee osteoarthritis.
- Trial name
- NCT06739954
- Testing
- Mulligan's Two Leg Rotation technique, Dry Needling
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Superior University