Clinical trials: Arthritis of Knee
Osteoarthritis, Knee
Evaluation of GW406381 in Treating Adults With Osteoarthritis Of The Knee
This study was designed to evaluate the effectiveness of GW406381 (a COX-2 inhibitor) in treating the signs and symptoms of osteoarthritis of the knee.
- Trial name
- NCT00120900
- Testing
- GW406381
- Where
- 19 sites in Denmark, Netherlands and 4 more
- Volunteers
- 1,340 people
- Sponsor
- GlaxoSmithKline
Knee Osteoarthritis (OA)
A Placebo-Controlled Study of Collagen Hydrolysate in Subjects With Knee Osteoarthritis (OA)
This study is designed to evaluate, by MRI, knee cartilage and structure in all subjects. Half the subjects in this study will take collagen hydrolysate each day for 48 weeks and the other half of the subjects will take a placebo…
- Trial name
- NMR (NCT00536302)
- Testing
- Collagen Hydrolysate
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- GELITA
Arthritis, Osteoarthritis
Tanezumab in Osteoarthritis of the Knee
Test the efficacy and safety of 3 doses in Osteoarthritis of the knee in patients.
- Trial name
- NCT00733902
- Testing
- tanezumab
- Where
- 82 sites in United States
- Volunteers
- 697 people
- Sponsor
- Pfizer
Osteoarthritis, Knee
Alignment Comparison Between TruMatch™ Personalized Solutions and Conventional Total Knee Replacement Instrumentation
This investigation is intended to provide clinical information about alignment using TruMatch™ and to compare the results to a conventional total knee replacement.
- Trial name
- NCT01108237
- Testing
- TruMatch™ Personalized Solutions, Total Knee Arthroplasty with Conventional Instrumentation.
- Where
- 4 sites in United States
- Volunteers
- 78 people
- Sponsor
- DePuy Orthopaedics
Osteoarthritis, Knee
Clinical Study to Evaluate Efficacy and Safety of ANT-301 in Patients With Knee Osteoarthritis in Grade III/IV by K/L
This is a phase I open study to evaluate the efficacy and safety of ANT-301 in patients with knee osteoarthritis K\&L Grade III/IV.
- Trial name
- NCT06539429
- Testing
- ANT-301
- Where
- South Korea
- Volunteers
- 6 people
- Sponsor
- Anterogen Co., Ltd.
Knee Osteoarthritis
Post Market Clinical Follow-Up Study- EVOLUTION® Revision CCK
Sponsor is conducting this post market clinical follow-up (PMCF) study to evaluate the safety and efficacy of its EVOLUTION® Revision CCK Tibia and EVOLUTION® Revision CCK Femur with EVOLUTION® CCK Tibial inserts.
- Trial name
- NCT04145401
- Testing
- Revision Knee implants
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- MicroPort Orthopedics Inc.
Knee Osteoarthritis
Sanomechanics® Rehabilitative Technology
Rehabilitative Sanomechanics Method (RSM) of exercise designed to restore normal subperiosteal transmission of in-joint pressures and normalizing contact pressures on cartilages, will reduce pain in the affected joints and…
- Trial name
- NCT05512507
- Testing
- Physical Therapy Program
- Volunteers
- 15 people
- Sponsor
- PolyOrth International
Osteoarthritis, Knee
Efficacy and Safety of Celecoxib Versus Ibuprofen in the Treatment of Osteoarthritis of the Knee (Europe)
To compare the efficacy and safety of celecoxib versus ibuprofen in subjects with osteoarthritis (OA) of the knee.
- Trial name
- NCT00630929
- Testing
- Ibuprofen, Celecoxib
- Where
- 33 sites in Germany, Spain and 1 more
- Volunteers
- 388 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Knee Osteoarthritis, Knee Osteoarthritis (OA)
Knee Osteoarthritis and Spa Therapy
The aim of this clinical trial is to assess the efficacy of the 18-day balneotherapy program (therapeutic indication: Rheumatology) in terms of functional incapacity and the disorders (pain, joint stiffness) induced by…
- Trial name
- SANTIAGO (NCT06617975)
- Testing
- Balneotherapy program in rheumatology indication
- Where
- France
- Volunteers
- 80 people
- Sponsor
- CEN Biotech
Osteoarthritis, Knee
Efficacy and Safety of Rebel Reliever Brace in Patients With Symptomatic Medial Knee Osteoarthritis
The purpose of the study is to evaluate the superiority of Rebel Reliever® knee brace + standard treatment versus standard treatment alone in terms of last 24-hour pain relief after 6 weeks.
- Trial name
- ROTOR (NCT02021136)
- Testing
- Rebel Reliever, Control
- Where
- France
- Volunteers
- 67 people
- Sponsor
- Thuasne
Knee Osteoarthritis
Study of Cingal for the Relief of Knee Osteoarthritis Compared to Triamcinolone Hexacetonide at 39 Weeks Follow up
Extension study to Cingal 16-02 to obtain 39-week safety and efficacy follow-up data
- Trial name
- Cingal17-02 (NCT03390036)
- Testing
- Cingal, Monovisc, Triamcinolone Hexacetonide
- Where
- 17 sites in Hungary, Poland
- Volunteers
- 526 people
- Sponsor
- Anika Therapeutics, Inc.
Osteoarthritis
Efficacy of ThermoProfen in Patients With Mild to Moderate Pain Associated With Osteoarthritis of the Knee
ThermoProfen is a transdermal ketoprofen patch that is integrated with a long-lasting CHADD (Controlled Heat-Assisted Drug Delivery) unit for the treatment of chronic pain associated with osteoarthritis.
- Trial name
- NCT00488267
- Testing
- ThermoProfen™ (Matrix Transdermal Ketoprofen/CHADD™ System)
- Where
- 36 sites in United States
- Volunteers
- 679 people
- Sponsor
- ZARS Pharma Inc.
Osteo Arthritis Knee
MISHA Post-Market Clinical Study
Prospective evaluation of the safety and effectiveness of the MISHA Knee System. The study will collect data on the procedural and long-term adverse events, WOMAC pain and function scores, KSS satisfaction, subsequent surgical…
- Trial name
- NCT06118892
- Testing
- MISHA Knee System
- Where
- 4 sites in United States
- Volunteers
- 120 people
- Sponsor
- Moximed
Knee Osteoarthritis
Study on Efficacy and Safety of Chondroitin Sulfate + Glucosamine Hydrochloride Versus Celecoxib in Knee Osteoarthritis
The purpose of this study is to determine whether the combination of Chondroitin sulfate (CS) and Glucosamine Hydrochloride (GH) has similar efficacy to Celecoxib (CE) in the treatment of patients with moderate to severe knee…
- Trial name
- MOVES (NCT01425853)
- Testing
- Chondroitin/Glucosamine (Droglican), Celecoxib
- Where
- Spain
- Volunteers
- 606 people
- Sponsor
- Bioiberica
Osteoarthritis
Efficacy of Proprietary Cherry Juice Blend in Osteoarthritis of the Knee
The primary purpose of this research study is to test the ability of a proprietary cherry juice blend to be helpful in the treatment of osteoarthritis (OA) of the knee.
- Trial name
- NCT00443092
- Testing
- proprietary cherry juice blend (food), control juice (kool aid blend)
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- CherryPharm
Knee Osteoarthritis
Patterned Electrical Neuromuscular Stimulation and Therapeutic Exercise for Osteoarthritis of the Knee: Pilot Study
The purpose of the study is to investigate the benefits of the Patterned Neuromuscular Electrical Stimulation (PENS) for the treatment of osteoarthritis.
- Trial name
- NCT00701506
- Testing
- Patterned Electrical Neuromuscular Stimulation
- Where
- Japan
- Volunteers
- 13 people
- Sponsor
- RS Medical
Osteoarthritis
Tanezumab In Osteoarthritis Of The Hip Or Knee
The purpose of the study is to test the efficacy and safety of 2 doses of tanezumab compared to oxycodone CR and placebo in patients with osteoarthritis
- Trial name
- NCT00985621
- Testing
- tanezumab 10 mg, tanezumab 5 mg, oxycodone
- Where
- 112 sites in United States, Austria and 5 more
- Volunteers
- 614 people
- Sponsor
- Pfizer
Osteoarthritis Thumb
Pivotal Study to Evaluate Efficacy and Safety of SP5M001 Inj. as Compared to Synovian Inj. in Patients With Mild to Moderate Knee Osteoarthritis
This is a randomized, double-blind, multicenter, non-inferiority, pivotal clinical trial to assess the efficacy and safety of the novel hexamethylenediamine (HMDA) cross-linked hyaluronate intra-articular injection (SP5M001)…
- Trial name
- NCT06307847
- Testing
- SP5M001 inj, Synovian inj
- Where
- 14 sites in South Korea
- Volunteers
- 223 people
- Sponsor
- Shin Poong Pharmaceutical Co. Ltd.
Osteoarthritis
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Rising Oral Doses of BI 1026706 in Male and Female Healthy Subjects and Patients With Osteoarthritis of the Knee
To investigate the safety and tolerability of BI 1026706 in male and female healthy subjects and osteoarthritis (OA) patients following oral administration of repeated rising doses To explore the pharmacokinetics after multiple…
- Trial name
- NCT02126826
- Testing
- BI 1026706
- Where
- Germany
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Osteoarthritis, Knee
A Controlled Study of an Herbal Topical Patch in Treating Osteoarthritis (OA) of the Knee
An evaluation of the safety and efficacy of an herbal patch in treating osteoarthritis pain of the right or left knee.
- Trial name
- NCT01183624
- Testing
- Herbal Patch
- Where
- 12 sites in China
- Volunteers
- 626 people
- Sponsor
- Johnson & Johnson Consumer and Personal Products Worldwide
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