Clinical trials: Arthrodesis
Medial Malleolus Fracture, Lisfranc Injury
Performance and Safety Evaluation of Inion CompressOn Screw in Foot and Ankle Surgeries. PMCF Investigation
The study in question is a post market clinical follow up (PMCF) study to evaluate the safety and performance of bioabsorbable headless compression screw Inion CompressOn in selected fracture, osteotomy and arthrodeses operations…
- Conditions
- Medial Malleolus Fracture, Lisfranc Injury, Lisfranc Fracture, Talus Fracture
- Trial name
- NCT05555459
- Testing
- Operation
- Where
- Finland
- Volunteers
- 125 people
- Sponsor
- Inion Oy
Knee Arthrodesis With Intramedullary Nail
Follow-up of Patients After Knee Arthrodesis With an Intramedullary Nail
Follow-up of patients who underwent a knee arthrodesis with different types of intramedullary nails.
- Trial name
- NCT00284297
- Testing
- History taken and clinical examination
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University Hospital, Ghent
Chirurgical Intervention
Effects of Osteopathic Management on Disability and Quality of Life After Lumbar Arthrodesis
The aim of our study is to assess the effect of a combined physiotherapy and osteopathy treatment versus a placebo on the management of disability and quality of life after lumbar arthrodesis.
- Trial name
- OSTEODESE (NCT06802120)
- Testing
- osteopathy real
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Clinique Bizet
Lumbar Degenerative Disease
Evaluation of Radiculitis Following Use of Bone Morphogenetic Protein-2 for Interbody Arthrodesis in Spinal Surgery
Clinician directed use of bone morphogenetic proteins (BMPs) in ways other than FDA approved, has increased recently due to the morbidity associated with harvest of iliac crest bone graft in spinal arthrodesis procedures.
- Trial name
- NCT00984672
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Mayo Clinic
Hyperpronated Foot, Reconstruction Surgeries of the Foot
Evaluate the Continued Safety and Performance of the Foot and Ankle Products
The objective of the registry is to evaluate the continued safety and performance of Arthrex foot and ankle products, including the ProStop® implant for hyperpronated foot; Bio-Compression Screw for reconstruction surgeries of…
- Conditions
- Hyperpronated Foot, Reconstruction Surgeries of the Foot, Fixation of Fractures and Fusion (Bunionectomy Osteotomies) of the Foot/Ankle, Fixation of Small Bone Fragments of the Foot/Ankle
- Trial name
- NCT04715139
- Testing
- Products listed in Group/Cohort Description
- Where
- 7 sites in United States, Germany and 1 more
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Arthrex, Inc.
Ankle and Hindfoot Arthrodesis
Long-term Safety and Effectiveness of AUGMENT® Injectable Bone Graft Compared to Autologous Bone Graft
The objective of this long-term study is to evaluate the long-term effectiveness and safety of AUGMENT® Injectable Bone Graft vs. autologous bone graft.
- Trial name
- NCT03998137
- Testing
- AUGMENT® Injectable Bone Graft, Standard of Care
- Volunteers
- 94 people
- Sponsor
- BioMimetic Therapeutics
Ankle Fractures, Pilon Fracture
FRAME Study (Frailty-Related Ankle Fracture Management and Evaluation)
This will be a multi-centre randomized controlled trial, with London Health Sciences Centre (LHSC) as the lead site. Elderly patients with complex ankle fractures who meet the inclusion criteria and provide consent will be…
- Trial name
- FRAME (NCT05131321)
- Testing
- Primary ankle arthrodesis (fusion), ORIF (open reduction and internal fixation), Intramedullary Fibular Nailing (IMFN)
- Where
- Canada
- Volunteers
- 172 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Arthritis Foot
Interest of Medial Partial Arthrodesis in Degenerative and Inflammatory Damage of Lisfranc Tarsometatarsal Joint.
Research Hypothesis: Lisfranc tarsometatarsal joint arthrodesis is a reliable surgical procedure, allowing the restoration of satisfactory function and a painless foot with an acceptable complication rate.
- Trial name
- NCT04937764
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Central Hospital, Nancy, France
Spinal Stenosis, Bilateral Lumbar Arthrodesis
Combined Analysis of Retrospective and Prospective Data From Patients Who Underwent Facet Arthroplasty With the TOPS™ System or the TOPS + Versalink™ Fixation System at a Single Center.
The TOPS™ system is an alternative to spinal fusion designed to stabilize-rather than fuse-the affected vertebral level, thereby relieving pain caused by degenerative spondylolisthesis and spinal stenosis.
- Trial name
- TOPS (NCT07845344)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 200 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Pilon Fracture, Arthritis
Anterior Tibiotalar Arthrodesis With Blade Plate Fixation
The aim of this study is to evaluate the clinical and radiographic outcomes of patients who have previously undergone tibiotalar arthrodesis using an anterior approach with blade-plate fixation for tibiotalar arthritis secondary…
- Trial name
- NCT01818466
- Sponsor
- University of Utah
Scaphoid Fractures, Distal Radius Fractures
Prospective Clinical Trial Comparing Infraclavicular Versus Axillary Approach to Brachial Plexus Block
The brachial plexus block is an anesthetic technique often used for surgical procedures of the upper limb. To get the brachial plexus block, several routes can be used, including the axillary and infraclavicular approach.
- Conditions
- Scaphoid Fractures, Distal Radius Fractures, Wrist Injury Arthrodesis
- Trial name
- NCT02208245
- Testing
- Ultrasound: Axillary block, Ultrasound: Infraclavicular block, Ropivacaine
- Where
- Brazil
- Volunteers
- 46 people
- Sponsor
- Federal University of São Paulo
Sacroiliitis, Sacroiliac; Fusion
Evaluation of the iFuse Bedrock Technique in Association With Posterior Lumbosacral Fusion With Iliac Fixation.
The purpose of this study is to describe the impact of the iFuse Bedrock technique to decrease post-operative pains in patients who underwent multilevel posterior lumbosacral fusion.
- Conditions
- Sacroiliitis, Sacroiliac; Fusion, Lumbosacral; Fusion, Spine Deformity
- Trial name
- NCT05276024
- Testing
- iFuse Bedrock technique
- Where
- 2 sites in France
- Volunteers
- 48 people
- Sponsor
- Polyclinique Bordeaux Nord Aquitaine
End-stage Ankle Arthritis (ESAA), Osteoarthritis (OA)
Comparing Ankle Fusion to Ankle Replacement
End-stage ankle arthritis (ESAA) is a debilitating condition associated with severe pain, dysfunction, and reduced quality of life.
- Trial name
- NCT01620541
- Testing
- Ankle Arthrodesis, Ankle Arthroplasty
- Where
- 6 sites in United States
- Volunteers
- 517 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Fracture;Pelvis, Sacral Fracture
Sacral Fracture Fusion/Fixation for Rapid Rehabilitation
To determine the safety and efficacy of concomitant sacral fracture fixation and sacroiliac (SI) joint fusion vs. non-surgical management for patients with debilitating sacral fragility or insufficiency fractures
- Conditions
- Fracture;Pelvis, Sacral Fracture, Sacroiliac; Fusion, Fragility Fracture
- Trial name
- SAFFRON (NCT05426356)
- Testing
- Surgical Intervention, Non-Surgical Management
- Where
- 7 sites in United States
- Volunteers
- 28 people
- Sponsor
- SI-BONE, Inc.
Pseudoarthrosis of Bone
SPECT/CT Bone Scan Quantification Surgery
The hypothesis of our study is that SPECT/CT bone scan fixation quantified by SUVMAX on a CZT solid state camera preoperatively would identify good responders to lumbar arthrodesis surgery.
- Trial name
- PERQUAL (NCT05183542)
- Testing
- Bone scan
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Central Hospital, Nancy, France
Sacro Iliac Joint Pain, Sacro-iliac Joints
Posterior-Inferior Intra-articular Cortical Piercing Titanium Implant for Sacroiliac Joint Fusion: Evaluation of Safety and Effectiveness Outcomes
The purpose of this study is to evaluate outcomes in patients treated with iFuse INTRA Ti for chronic SI joint pain.
- Conditions
- Sacro Iliac Joint Pain, Sacro-iliac Joints, Sacroiliac Disorder, Sacroiliac Joint Dysfunction
- Trial name
- PIERCE (NCT07565545)
- Testing
- iFuse INTRA Ti Implant System
- Volunteers
- 120 people
- Sponsor
- SI-BONE, Inc.
Arthritis
Observational Study of Total Ankle Arthroplasty and Tibiotalar Arthrodesis
In case of severe ankle arthritis, the two common surgical treatments are tibiotalar arthrodesis and total ankle arthroplasty. Few studies have compared these treatments and it remains difficult to determine which operation is…
- Trial name
- NCT02025946
- Where
- 8 sites in Belgium, France and 5 more
- Sponsor
- Integra LifeSciences Services
Post-operative Pain
Added Value of Local Clonidine for Spine Postoperative Pain Control, in Addition to Bupivacaine
The objective of this prospective randomized double-blind study is to evaluate the added analgesic value of clonidine to the conventional local bupivacaine wound infiltration in posterior spine surgery.
- Trial name
- NCT01902108
- Testing
- Bupivacaine, Clonidine
- Where
- Lebanon
- Volunteers
- 225 people
- Sponsor
- St Joseph University, Beirut, Lebanon
Disc Degeneration
Comparaison of Interbody Bone Fusion Between Two Osteoinductive Bioactive Bone Substitutes After Anterior Lumbar Interbody Arthrodesis in Degenerative Lumbar Disc Surgery in Adults
Disc degeneration is a progressive deterioration process of the intervertebral disc, which can manifest as significant low back pain and a loss of mobility that interferes with daily activities.
- Trial name
- FUSALIF (NCT07044206)
- Testing
- Use of bone substitute during intervertebral fusion surgery
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Wrist Arthritis
Clinical and Patient-reported Outcomes After Total Wrist Arthroplasty and Total Wrist Arthrodesis
The wrist is often considered to be the fundament of the hand. Patients with a destroyed wrist joint caused by osteoarthritis or rheumatoid arthritis may suffer from pain and functional disabilities with impaired life quality.
- Trial name
- NCT05693636
- Testing
- Total wrist arthroplasty
- Volunteers
- 51 people
- Sponsor
- Region Skane