Clinical trials: Arthropathy of Knee
Knee Osteoarthritis
Knee Injections for the Clinical Management of Knee OsteoArthritis
Knee osteoarthritis (OA) is an incurable disease that involves breakdown of the knee joint. This breakdown is often accompanied by knee pain and stiffness, which can limit a person's daily physical activity.
- Trial name
- KICK-OA (NCT04595890)
- Testing
- Arthrex Angel System used to prepare injection of Bone Marrow Concentrate (BMC), Saline injection
- Where
- United States
- Sponsor
- University of Delaware
Osteoarthritis, Knee, Rheumatoid Arthritis of Knee
Evaluation of The Safety And Performance of The Freedom Total Knee® System With The PEEK-OPTIMA Femoral Component
Prospective, multi-centre, non-comparative, post-market surveillance clinical study
- Conditions
- Osteoarthritis, Knee, Rheumatoid Arthritis of Knee, Traumatic Arthritis of Knee (Diagnosis), Polyarthritis
- Trial name
- NCT03224689
- Testing
- PEEK-Optima Femoral Component
- Where
- Belgium
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Maxx Orthopedics Inc
Osteoarthritis, Pain
An Investigation Into the Role of Walking in Treating the Symptoms of Knee Osteoarthritis: The WalkOut Study
There are over 8.75 million people in the United Kingdom with osteoarthritis in their knees. The effect of this condition can be debilitating. Symptoms are due to wear and tear of the knee joint.
- Conditions
- Osteoarthritis, Pain, Arthritis, Gonarthritis
- Trial name
- WalkOut (NCT02748291)
- Testing
- Walking, Department of Health Physical Activity Guidelines
- Where
- United Kingdom
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Knee Osteoarthritis
Circuit Training on Knee Osteoarthritis Patients
Introduction: The increase in intermuscular adipose tissue (IMAT) can contribute to muscle weakness and consequently on progression of knee OA.
- Trial name
- NCT02761590
- Testing
- Circuit training protocol
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Universidade Federal de Sao Carlos
Osteoarthritis, Knee, Postoperative Pain
A Randomized Comparison of the Efficacy of the IPACK Block Versus the Popliteal Plexus Block for Posterior Knee Analgesia, in Patients Undergoing a Total Knee Arthroplasty and Receiving a Continuous Distal Femoral Triangle Block
Total knee arthroplasty (TKA) is commonly associated with significant postoperative pain, including pain arising from the posterior aspect of the knee.
- Trial name
- NCT07876310
- Testing
- Ultrasound-Guided iPACK Block, Ultrasound-Guided Popliteal Plexus Block, Ultrasound-Guided Continuous Femoral Triangle Block
- Volunteers
- 136 people
- Sponsor
- Clinica Santa Maria
Osteoarthritis, Osteo Arthritis Knee
Exercise on Knee OA With the Star Excursion Balance Test
Osteoarthritis is a prevalent and disabling condition. Exercise is recommended to maintain strength and mobility, and to decrease pain.
- Trial name
- NCT03450486
- Testing
- exercise
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Western University, Canada
Knee Osteoarthritis
Efficacy of Dehydrated Cell and Protein Concentrate Versus Corticosteroid
To compare the efficacy of Ascent injection versus corticosteroid injection in treating knee osteoarthritis.
- Trial name
- NCT03710005
- Testing
- Ascent, Standard
- Where
- 4 sites in United States
- Volunteers
- 51 people
- Sponsor
- StimLabs
Knee Osteoarthritis
Comparison of Single Intra-articular Injection of Hyruan-One With Hylan G-F 20 in Knee Osteoarthritis
We compare the efficacy of intra-articular injection of Hyruan-One with Hylan G-F 20 and placebo (NSS) controlled in a double-blind RCT.
- Trial name
- NCT03484091
- Testing
- Hyruan-One, Hylan G-F 20, Normal saline
- Where
- Thailand
- Volunteers
- 276 people
- Sponsor
- Thammasat University
Osteoarthritis
Clinical Trial of Allogenic Adipose Tissue-Derived Mesenchymal Progenitor Cells Therapy for Knee Osteoarthritis
Evaluate the safety and efficacy of Allogenic Adipose Tissue-Derived Mesenchymal Progenitor Cells Therapy for Knee Osteoarthritis.
- Trial name
- NCT02641860
- Testing
- Mesenchymal progenitor cells
- Where
- China
- Volunteers
- 22 people
- Sponsor
- Shanghai AbelZeta Ltd.
Osteoarthritis, Knee, Hypertension
Staying Active With Arthritis: RCT of Physical Activity for Older Adults With Osteoarthritis and Hypertension
The purpose of the Staying Active with Arthritis (STAR) research study is to determine if a 6-month program will improve leg exercise, fitness walking, and clinical outcomes (function, blood pressure, leg strength, pain, fatigue…
- Trial name
- STAR (NCT01280903)
- Testing
- STAR Intervention, Attention-Control
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- University of Pittsburgh
Osteoarthritis, Knee
Comparative Study of CT and Fluoroscopic Guided Genicular Nerve Ablation in the Treatment of Knee Osteoarthritis
The goal of this study is to evaluate the comparative effectiveness of CT-guided and fluoroscopic-guided genicular nerve ablation in reducing knee pain and improving function in adults diagnosed with knee osteoarthritis…
- Trial name
- NCT06514703
- Testing
- CT-Guided Genicular Nerve Ablation, Fluoroscopic-Guided Genicular Nerve Ablation
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Zagazig University
Osteoarthritis, Hyperthyroidism
Povidone Iodine Irrıgation at Hip-Knee Arthroplasty
Povidone iodine (PI) solution is an antimicrobial solution that can be used at hip and knee arthroplasty cases. It contains iodine that may be absorbed by the body.
- Conditions
- Osteoarthritis, Hyperthyroidism, Iodine Toxicity
- Trial name
- NCT05599841
- Testing
- PI solution, Saline Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara University
Osteoarthritis, Knee
A Study of LY2828360 in Patients With Osteoarthritic Knee Pain
To investigate the safety, efficacy and pharmacokinetics of single daily oral dose of LY2828360 in male and female subjects with osteoarthritic knee pain
- Trial name
- NCT01319929
- Testing
- LY2828360
- Where
- Denmark
- Volunteers
- 39 people
- Sponsor
- Eli Lilly and Company
Patellofemoral Pain Syndrome
Comparative Effects Of Clamshell And Short Arc Quadriceps Exercises In Patellofemoral Pain
This is a research study to compare two different exercises for people who have patellofemoral pain syndrome. Patellofemoral pain syndrome means pain around or behind the kneecap, which is also called "runner's knee".
- Trial name
- CASCAPE-PFPS (NCT07646431)
- Testing
- Clamshell Exercise, Short Arc Quadriceps Exercise
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Green International University
Knee Osteoarthritis, Knee Disease
ESPB vs FICB for Pain Management Following Total Hip Prosthesis Surgery
Hip arthroplasty surgery is frequently performed on elderly patients in the community and it is associated with long-term postoperative hospital stays and high mortality.
- Conditions
- Knee Osteoarthritis, Knee Disease, Knee Arthritis
- Trial name
- NCT05621161
- Testing
- Postoperative analgesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Mursel Ekinci
Osteoarthritis
Use of Pulsed Electromagnetic Fields for Postoperative Knee Pain
The purpose of this study is to determine whether the Torino II device, which emits a pulsed electromagnetic field), will help to decrease pain and swelling after knee replacement surgery, and thereby decrease the use of narcotic…
- Trial name
- NCT01415856
- Testing
- Active Device (Torino II)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Center for Joint Surgery and Sports Medicine, Maryland
Anterior Cruciate Ligament Reconstruction
Intraarticular Injection of Tranexamic Acid Reduced Postoperative Hemarthrosis in Arthroscopic Anterior Cruciate Ligament Reconstruction
Post-anterior cruciate ligament reconstruction (ACLR) hemarthrosis may result in increased pain thus delaying postoperative rehabilitation, which may eventually lead to arthrofibrosis and a functional deficit.
- Trial name
- NCT03580018
- Testing
- Tranexamic Acid Powder, Post-anterior cruciate ligament reconstruction (ACLR)
- Where
- Taiwan
- Volunteers
- 320 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Knee Arthritis, Knee Arthropathy
ESPB vs iPACK+ACB in Total Knee Arthroplasty
Effect of iPACK block with Adductor Canal Block and ESPB on pain management, and NLR and PLR following knee arthroplasty
- Conditions
- Knee Arthritis, Knee Arthropathy, Knee Osteoarthritis, Knee Pain Chronic
- Trial name
- NCT06302218
- Testing
- Ropivacaine 0.2% Injectable Solution, control group
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Knee Osteoarthritis
Efficacy of Radial Shockwave Therapy for Treatment of Pain in Knee Osteoarthritis
The objective of this study is to compare the results of 2000 impulses of radius shockwaves per week with 2000 placebo shockwaves on the treatment of pain and functional incapacity of patients with severe primary knee…
- Trial name
- NCT02197962
- Testing
- Extracorporeal Radial shockwaves
- Where
- 2 sites in Brazil
- Volunteers
- 105 people
- Sponsor
- Marta Imamura
Osteoarthritis of the Knee
Shengyu Decoction and Lijin Manipulation for Knee OA: 3D Gait Analysis
Detailed Description Avoid duplicating information that will be entered or uploaded elsewhere in the record.
- Trial name
- NCT06451783
- Testing
- Traditional Chinese medicine combined with manipulation treatment, Celecoxib capsule
- Where
- China
- Volunteers
- 94 people
- Sponsor
- Xuhui Central Hospital, Shanghai
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