Clinical trials: Arthroplasties, Replacement
Knee Osteoarthritis
Effects of Tele-prehabilitation in Patients Waiting for Knee Replacement
After knee arthroplasty rehabilitation is fundamental to patient's functional recovery, but in recent years there has been a growing interest in the possibility to prepare patients for surgery through a "prehabilitation" program.
- Trial name
- NCT05668312
- Testing
- Tele-prehabilitation, Standard prehabilitation
- Where
- 2 sites in Italy
- Volunteers
- 68 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Arthroplasty, Replacement, Knee
Preoperative Prediction of Postoperative Physical Function
End-stage KOA results in limitations in activities of daily life (ADL), work and leisure. Treatment for KOA is a stepped care process starting with a conservative approach and in which joint replacement surgery can be considered…
- Trial name
- NCT05602701
- Testing
- Preoperative assessment
- Where
- 3 sites in Netherlands
- Volunteers
- 40 people
- Sponsor
- Maastricht University Medical Center
Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
Antibiotic Prophylaxis in Primary Joint Arthroplasty of the Hip and Knee.
A retrospective study will be performed to compare the incidence of revision procedures performed for the treatment of postoperative periprosthetic joint infection (PJI) between patients treated with a single preoperative…
- Conditions
- Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee, Antibiotic Prophylaxis
- Trial name
- NCT03348254
- Testing
- Single shot antibiotic prophylaxis, Multiple shot antibiotic prophylaxis
- Where
- Netherlands
- Volunteers
- 242,179 people
- Sponsor
- Onze Lieve Vrouwe Gasthuis
Knee Osteoarthritis, Rehabilitation
Preoperative Rehabilitation in Greek Patients Undergoing Total Knee Arthroplasty
Purpose: The purpose of this study was to investigate the efficacy of a 6-week supervised high-intensity preoperative training program on muscle strength, functional performance and patient-reported outcomes in patients…
- Trial name
- NCT04911205
- Testing
- Preoperative training program
- Volunteers
- 88 people
- Sponsor
- National and Kapodistrian University of Athens
Knee Osteoarthritis
MultiCenter IDE Study of the PEEK-OPTIMA™ Femoral Component vs a CoCr Alloy TKA Femoral Component of Similar Design
The purpose of this investigational device exemption (IDE) study is to monitor the performance (safety and efficacy) of the Maxx Orthopedics, Freedom Total Knee® System, with a femoral component of similar design, manufactured…
- Trial name
- NCT06627673
- Testing
- Total Knee Arthroplasty
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Maxx Orthopedics Inc
Osteoarthritis
Improving Services and Outcomes for Joint Replacement Patients
Primary total knee or total hip replacement surgeries are costly high volume procedures \& outcomes may be affected by surgical \& care processes \& individual patient characteristics.
- Trial name
- NCT01899443
- Testing
- Observation
- Where
- 18 sites in Australia
- Volunteers
- 1,900 people
- Sponsor
- South West Sydney Local Health District
Central Sensitisation, Postoperative Pain
Evaluation of the Effect of Central Sensitivity on Pain and Functional Status After Total Knee Joint Replacement Surgery
The study is a prospective observational study designed to determine the effects of central sensitization on pain and functional status of patients before and after total knee joint replacement surgery.
- Conditions
- Central Sensitisation, Postoperative Pain, Arthritis
- Trial name
- NCT06553118
- Testing
- Total knee arthroplasty
- Volunteers
- 80 people
- Sponsor
- Istanbul University
Ossification, Heterotopic
Prevention of Heterotopic Ossification With Arcoxia After Total Hip Replacement
The purpose of the study is to determine whether Arcoxia is effective in preventing heterotopic ossification after total hip arthroplasty.
- Trial name
- Arcoxia (NCT01022190)
- Testing
- Etoricoxib (Arcoxia)
- Where
- Netherlands
- Volunteers
- 42 people
- Sponsor
- Radboud University Medical Center
Direct Infection of Hip- and Knee Arthroplasty
Debridement, Antibiotics and Implant Retention in Early Periprosthetic Joint Infection: A Retrospective Cohort Study
Introduction: Periprosthetic joint infection (PJI) is a common cause for reoperation after knee and hip arthroplasty surgery. Debridement, antibiotics and implant retention (DAIR) is recommended in early infections (< 4 weeks)…
- Trial name
- DAIR (NCT02087020)
- Testing
- Debridement, antibiotics and implant retention
- Where
- Sweden
- Volunteers
- 51 people
- Sponsor
- Danderyd Hospital
Hip Osteoarthritis, Knee Osteoarthritis
Efficacy of a Digital Biofeedback System for Home-based Rehabilitation After Total Joint Replacement
The study was designed to assess the efficacy of a home-based rehabilitation program using a digital kinematic biofeedback system after total hip or knee replacement. This is a single-arm prospective study.
- Trial name
- NCT03648060
- Testing
- Digital kinematic biofeedback system
- Where
- Portugal
- Volunteers
- 88 people
- Sponsor
- Sword Health, SA
Joint (Knee or Hip Replacement), Infection as Complication of Medical Care
Swiss Revision Cohort
This study follows patients with infections after a joint replacement over time. During follow-up, treatment outcomes are carefully measured to determine whether the infection can be cured.
- Trial name
- REVCO (NCT07473089)
- Testing
- Revision for periprosthetic joint infections of the hip, knee, shoulder, elbow or ankle
- Where
- 5 sites in Switzerland
- Volunteers
- 329 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Metastatic Cancer to the Hip
Fully Constrained Acetabular Liner vs. Dual Mobility Hip Joint in the Surgical Treatment of Metastatic Bone Disease of the Hip
The purpose of the current study is to investigate whether dual mobility liners are non-inferior til constrained liners regarding the post-operative hip joint dislocation risk following total hip replacement in patients with…
- Trial name
- NCT05461313
- Testing
- Constrained Liner, Dual Mobility
- Where
- Denmark
- Volunteers
- 146 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Auriculotherapy, Arthroplasty, Replacement, Knee
The Role of Auricular Point Diagnosis and Treatment in ERAS During TKA
To further improve the surgical outcomes of patients undergoing total knee arthroplasty (TKA). This study aims to use ear acupoint therapy to address the following clinical issues: 1 The degree of postoperative inflammation and…
- Conditions
- Auriculotherapy, Arthroplasty, Replacement, Knee, Enhanced Recovery After Surgery
- Trial name
- NCT06273488
- Testing
- Auriculotherapy
- Where
- China
- Volunteers
- 116 people
- Sponsor
- Peking Union Medical College
Pain, Postoperative
Biopsychosocial Impact on Caregivers in Patients Undergoing Joint and Spine Surgery
The purpose of this study is to describe the biopsychosocial impact of caregivers in patients undergoing total knee arthroplasty, total hip arthroplasty, and cervical/thoracic/lumbar spine surgery.Defining such impacts may offer…
- Trial name
- NCT03059602
- Testing
- No specific treatment based intervention-health measurement instrument
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Defense and Veterans Center for Integrative Pain Management
Osteo Arthritis Shoulders, Avascular Necrosis of the Head of Humerus
Easytech Reversed Shoulder System Clinical Study
The purpose of the study is to collect data to demonstrate the safety and effectiveness of the Easytech Reversed Shoulder System for the treatment of patients who require a reverse total shoulder arthroplasty.
- Conditions
- Osteo Arthritis Shoulders, Avascular Necrosis of the Head of Humerus, Rotator Cuff Tear
- Trial name
- NCT03806842
- Testing
- Easytech group
- Where
- 6 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- FX Shoulder Solutions
Shoulder Pain, Shoulder Arthritis
Subscapularis Indocyanine Green Perfusion Pilot Study
The Purpose of this pilot study is to evaluate the feasibility of open wide-field imaging of indocyanine green ingress and egress during total shoulder arthroplasty.
- Conditions
- Shoulder Pain, Shoulder Arthritis, Shoulder Arthroplasty
- Trial name
- ICG (NCT05179941)
- Testing
- Perfusion with Indocyanine green
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Knee Arthropathy, Post Operative Pain
Function and Pain Following Knee Replacement
The goal of this interventional study is to compare pain management techniques (femoral nerve block, intra-articular block, none) in TKA patients.
- Conditions
- Knee Arthropathy, Post Operative Pain, Pain, Postoperative
- Trial name
- NCT05478005
- Testing
- Femoral nerve block, Intra-articular block
- Where
- Israel
- Volunteers
- 54 people
- Sponsor
- University of Haifa
Foramen Ovale, Patent, Delirium
Patent Foramen Ovale and the Risk of Postoperative Delirium Following Elective Hip and Knee Arthroplasty Surgeries
This study will involve patients who are planned to have hip or knee replacement surgeries. They will undergo a Transthoracic Echocardiogram study (an ultrasound of the heart) to look for a Patent Foramen Ovale (PFO).
- Conditions
- Foramen Ovale, Patent, Delirium, Arthroplasty, Replacement, Hip, Arthroplasty, Replacement, Knee
- Trial name
- NCT02400892
- Testing
- TTE Bubble Study
- Where
- Canada
- Volunteers
- 226 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Osteoarthritis, Hip, Arthritis
A Clinical Investigation of the M2a-Magnum™ Hip System
The purpose of this prospective clinical data collection is to document the performance and clinical outcomes of the M2a-Magnum™ Hip System
- Conditions
- Osteoarthritis, Hip, Arthritis, Rheumatoid Arthritis, Joint Disease
- Trial name
- NCT00698347
- Testing
- M2a-Magnum™ Hip System
- Volunteers
- 249 people
- Sponsor
- Biomet Orthopedics, LLC
Osteo Arthritis Knee, Total Knee Arthroplasty
Comparing Surgical and Economical Parameters of Total Knee Replacement.
Randomized study comparing surgical and economic parameter of Total Knee Arthroplasty performed using two different specific surgical techniques.
- Trial name
- NCT03427047
- Testing
- MyKnee with single use Efficiency Instrument, Stryker Navigational with conventional metal instruments
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Medacta USA
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