Clinical trials: Arthroplasties, Replacement
Adrenal Cortex Hormones, Arthroplasty, Replacement, Knee
Comparing Different Doses of Corticosteroids in Local Infiltration Analgesia (LIA) for Total Knee Arthroplasty
This study aims to compare the efficacy of different doses of glucocorticoids in local infiltration analgesia (LIA) during total knee arthroplasty (TKA) through a prospective single-center randomized controlled trial, and to…
- Conditions
- Adrenal Cortex Hormones, Arthroplasty, Replacement, Knee, Anesthesia, Local
- Trial name
- NCT07337772
- Testing
- LIA with different doses of Diprospan
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Periprosthetic Joint Infection
Intraoperative Microbial Contamination
This is a randomized, controlled study which aims to show whether iodine impregnated incisional foil (IobanTM) has a place in the prevention of prosthetic joint infection (PJI).
- Trial name
- ICON (NCT03139539)
- Testing
- Ioban
- Where
- 3 sites in Denmark
- Volunteers
- 1,661 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Osteoarthritis
DSJ-2016-07 ATTUNE® Cementless CR RP Japan
The primary objective is to investigate the change from pre-operative baseline to two year postoperative functional performance improvement for the ATTUNE® primary, cementless TKA RP system as measured with the KOOS questionnaire…
- Trial name
- NCT03193034
- Testing
- Cementless Total Knee Arthroplasty
- Where
- 4 sites in Japan
- Volunteers
- 81 people
- Sponsor
- DePuy Orthopaedics
Distal Femur Fracture
Distal Femur Fx: ORIF(Open Reduction and Internal Fixation) vs DFR (Distal Femur Replacement Total Knee Arthroplasty)
Supracondylar femur periprosthetic fractures about a total knee arthroplasty (TKA) are a catastrophic and challenging complication of TKA and unfortunately are increasing in incidence.
- Trial name
- NCT05792189
- Testing
- Timed Up and Go Test on subjects with ORIF of distal femur fractures, Koos Jr assesment on subjects with ORIF of distal femur fractures, Timed Up and Go Test on subjects with DFR of distal femur fracture
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Florida
Osteoarthritis, Knee, Osteoarthritis, Hip
Study Evaluating the Efficacy of Joint Replacement
Patient-related outcomes were originally designed to measure outcomes in clinical studies. They were not developed to predict outcomes, however, different studies showed close association between values achieved preoperatively…
- Trial name
- SEVERE (NCT04691466)
- Testing
- Joint replacement
- Where
- Poland
- Volunteers
- 1,000 people
- Sponsor
- Nicolaus Copernicus University
Osteoarthritis
Study of AQUACEL™ Ag Surgical Cover Dressing Following Total Knee Replacement
The aim of the study is to determine whether the AQUACEL™ Ag SURGICAL cover dressing is successful in reducing the incidence of wound infection in high risk patients following total knee replacement.
- Trial name
- NCT02217202
- Testing
- Aquacel Ag dressing
- Sponsor
- Golden Jubilee National Hospital
Arthroplasty, Replacement, Shoulder
S-33 SMR Shoulder HP Reverse Glenosphere
Study Design: Single arm, retrospective and prospective, single center, post-market clinical study Purpose:To demonstrate the safety and effectiveness of the SMR Reverse HP Shoulder System device for primary, fracture or revision…
- Trial name
- NCT05339815
- Testing
- SMR shoulder arthroplasty
- Where
- United Kingdom
- Volunteers
- 205 people
- Sponsor
- Limacorporate S.p.a
Osteoarthritis, Hip
Dual Energy X-ray Absorptiometry (DXA) Comparison Hip Resurfacing Versus Total Hip Arthroplasty (THA)
This study compares the change (loss) of bone mineral density (BMD) that occurs in the proximal femur after hip resurfacing and total hip replacement.
- Trial name
- NCT01359527
- Testing
- Hip Resurfacing, Total Hip Arthroplasty
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Spokane Joint Replacement Center
Hip Replacement in Osteoarthritis Patients
RSA Study of Furlong Evolution With and Without Collar
The aim of this study is to further investigate the clinical and radiological importance of design changes in cementless hip prosthesis.
- Trial name
- NCT01894854
- Testing
- Stem collar
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Region Skane
Arthroplasty, Replacement, Hip
Visibility of Site Marking for Surgical Time Out With Two Different Skin Preparation Solutions
Skin preparation solutions are used to clean the skin of the patient before surgery to decrease the rate of infection. This is particularly important for hip replacement to reduce the risk of prosthetic joint infection.
- Trial name
- site marking (NCT00739583)
- Testing
- CHG 2% w/v and IPA 70% v/v, Iodophor 0.7% and IPA 74% w/w
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Arthritis, Rheumatoid
Study of People With Rheumatoid Arthritis Who Require Joint Surgery in the Hand
A procedure called silicone metacarpophalangeal joint arthroplasty (SMPA) is sometimes used to treat knuckle deformity in the hands of rheumatoid arthritis (RA) patients.
- Trial name
- NCT00124254
- Testing
- Silicone metacarpophalangeal joint arthroplasty, Usual care
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 170 people
- Sponsor
- University of Michigan
Acute Pain, Regional Anesthesia Morbidity
A Trial Comparing Adductor Canal Catheter and Intraarticular Catheter Following Primary Total Knee Arthroplasty
The study is a prospective randomized controlled trial comparing intraarticular catheters and adductor canal catheters for postoperative analgesia following a primary Total Knee Arthroplasty (TKA).
- Trial name
- NCT02497911
- Testing
- Adductor Canal Catheter, Intraarticular Catheter, Ropivicaine
- Volunteers
- 110 people
- Sponsor
- Thomas Jefferson University
Avascular Necrosis of Hip, Total Hip Replacement Arthroplasty
Rotational Thromboelstometry (ROTEM) change_colloid_total Hip Replacement Arthroplasty
The investigators administered different kinds of colloids before transfusion of red blood cell to patient undergoing total hip replacement arthroplasty.
- Trial name
- NCT01512628
- Testing
- Pentaspan, voluven, volulyte
- Where
- South Korea
- Volunteers
- 75 people
- Sponsor
- Seoul National University Bundang Hospital
Arthroplasty, Replacement, Knee
Wearable Sensors for Monitoring Recovery After Total Knee Arthroplasty
The goal of this observational study is to investigate the potential of wearable sensors for monitoring the postoperative recovery of patients after TKA.
- Trial name
- NCT05992064
- Testing
- Measuring gait
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Aalborg University Hospital
Arthropathy of Hip
Clinical Analysis of Suction Drainage in Cementless Hip Replacement
Randomized prospective study assessing suction drainage in total hip arthroplasty. Group without drainage, 50 hips, compared with group with suction drainage, 50 hips.
- Trial name
- NCT04333264
- Testing
- suction drainage, no suction drainage
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bartosz Paweł
Knee Osteoarthritis, Joint Disease
Multi-variable Prediction Model of Total Knee Replacement Outcome
Total knee arthroplasty (TKA) is a surgical procedure applied as a common solution to overcome limitations produced by advanced stages of severe gonarthrosis.
- Conditions
- Knee Osteoarthritis, Joint Disease, Total Knee Replacement, Arthroplasty Complications
- Trial name
- NCT03894514
- Where
- Spain
- Volunteers
- 243 people
- Sponsor
- University of Valencia
Total Knee Replacement
The Efficacy of Low-load Blood Flow Restricted Resistance Before TKR
The primary aim of this study is to investigate the efficacy of 8 weeks of Low-load blood flow restricted exercise (BFRE) compared to receiving standard care only (no preoperative training) before total knee replacement (TKR) on…
- Trial name
- NCT04081493
- Testing
- Low-load blood flow restricted exercise
- Where
- 3 sites in Denmark
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Total Knee Replacement, Total Hip Replacement
Post Op Home Monitoring After Joint Replacements
The investigators propose to deploy an interactive device to monitor the patient's recovery and vital signs at home after joint replacements. These will be early discharge patients on the same day or the next morning.
- Trial name
- POHM (NCT02143232)
- Testing
- remote patient monitoring (Telus RPM)
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- Ottawa Hospital Research Institute
Arthroplasty, Hip Replacement, Anemia
Postoperative Anemia and Functional Outcomes After Fast-track Primary Hip Arthroplasty
The purpose of this study is to evaluate the possible association between postoperative anaemia and functional outcomes the first 2 weeks after primary hip arthroplasty.
- Trial name
- NCT01514006
- Where
- 2 sites in Denmark
- Volunteers
- 125 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Arthroplasty, Replacement, Thromboembolism
Pradaxa (Dabigatran Etexilate) 150 mg/q.d. in Patients With Moderate Renal Impairment After Hip or Knee Replacement Surgery
An observational cohort study on safety and efficacy to generate additional data on the benefit/risk profile of the 150 mg dose of Pradaxa in patients with renal impairment
- Trial name
- NCT00847301
- Where
- 53 sites in Austria, France and 5 more
- Volunteers
- 472 people
- Sponsor
- Boehringer Ingelheim
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