Clinical trials: Arthroplasties, Replacement
Arthroplasty, Replacement, Knee, Total Knee Replacement
Metal Ion Concentrations After Total Knee Arthroplasty
The purpose of this study is to analyze the metal ion concentrations in the patients blood following robotic-assisted total knee arthroplasty (TKA) compared to conventional total knee arthroplasty using cutting guides.
- Conditions
- Arthroplasty, Replacement, Knee, Total Knee Replacement, Blood Metal Ion Concentration
- Trial name
- NCT06447922
- Testing
- Metal ion level testing
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Arthroplasty, Replacement, Hip, Osteoarthritis, Hip
Antibiotic Impregnated Bone Graft to Reduce Infection in Hip Replacement.
Total hip replacement is the most successful treatment modern healthcare can offer patients to regain quality of life. Periprosthetic joint infection (PJI) is the most common and devastating complication after total hip…
- Conditions
- Arthroplasty, Replacement, Hip, Osteoarthritis, Hip, Antibiotic Resistant Infection, Prosthetic Joint Infection
- Trial name
- ABOGRAFT (NCT05169229)
- Testing
- Vancomycin + Tobramycin, Saline
- Where
- Sweden
- Volunteers
- 1,100 people
- Sponsor
- University Hospital, Linkoeping
Arthroplasty Replacement, Knee, Anesthesia Conduction
Migration Rate for Continuous Adductor Canal Block Catheters After Primary Total Knee Arthroplasty Surgery: a Comparison Between Two Insertion Techniques
Continuous adductor canal block (CACB) is becoming increasingly popular for providing postoperative analgesia following knee arthroplasties.
- Trial name
- ISAFExOOPS (NCT07681622)
- Testing
- ISAFE technique for adductor canal catheter insertion, OOPS technique
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Arthroplasty Replacement, Knee, Arthroplasty Total Hip Replacement
A Prospective, Single-arm, Trial to Determine Contamination Rates When Using an Antibacterial Incise Drape During Orthopedic Surgery
The goal of this clinical study is to generate data on the intended use of a chlorhexidine gluconate (CHG)-impregnated antimicrobial incise drape.
- Trial name
- NCT07356323
- Testing
- 3M™ Ioban™ CHG Chlorhexidine Gluconate Incise Drape (2% w/w CHG)
- Where
- 2 sites in United States
- Volunteers
- 179 people
- Sponsor
- Solventum US LLC
Arthroplasty, Replacement
To Evaluate the Performance of the CORI™ KNEE TENSIONER as an Accessory to the CORI™ Surgical System.
To evaluate the performance of the CORI™ KNEE TENSIONER as an accessory to the CORI™ Surgical System.
- Conditions
- Arthroplasty, Replacement, Knee
- Trial name
- NCT04849884
- Testing
- CORI™ KNEE TENSIONER
- Where
- 4 sites in United States
- Volunteers
- 77 people
- Sponsor
- Smith & Nephew, Inc.
Hip Osteoarthritis, Arthroplasty, Replacement, Hip
Preoperative Fasting and the Gut Microbiome Before Hip Replacement
Postoperative complications occur in 5-15% of patients undergoing elective primary total hip arthroplasty (THA), including periprosthetic joint infection (PJI), thrombosis, wound healing disorders, and metabolic dysregulation.
- Conditions
- Hip Osteoarthritis, Arthroplasty, Replacement, Hip, Postoperative Complications, Surgical Wound Infection
- Trial name
- PreFAST-Hip (NCT07651462)
- Testing
- Buchinger Fastenbox + intermittent fasting (20-day preoperative schedule)
- Where
- Germany
- Volunteers
- 130 people
- Sponsor
- Charite University, Berlin, Germany
Arthroplasty, Replacement, Knee, Total Knee Arthroplasty
Systemic Lidocaine Versus Ultrasound-guided Adductor Canal Block for Patients Undergoing Total Knee Arthroplasty
The investigators are evaluating the postoperative outcomes in patients undergoing total knee arthroplasty that receive either systemic lidocaine or ultrasound-guided adductor canal block as part of their anesthetic plan.
- Trial name
- ACBSL (NCT04828083)
- Testing
- Lidocaine IV, Saline IV
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Rhode Island Hospital
Arthroplasty, Replacement, Knee, Osteoarthritis, Knee
TracPatch in Total Knee Arthroplasty
Total Knee Arthroplasty is becoming an increasingly common operation. An important part of a successful overall patient outcome is regaining functional range of motion after surgery.
- Trial name
- NCT03466476
- Testing
- Consensus TracPatch
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Miami
Arthroplasty, Replacement, Shoulder
S-33 SMR Shoulder HP Reverse Glenosphere
Study Design: Single arm, retrospective and prospective, single center, post-market clinical study Purpose:To demonstrate the safety and effectiveness of the SMR Reverse HP Shoulder System device for primary, fracture or revision…
- Trial name
- NCT05339815
- Testing
- SMR shoulder arthroplasty
- Where
- United Kingdom
- Volunteers
- 205 people
- Sponsor
- Limacorporate S.p.a
Orthopedic Disorder, Humerus Fracture
Early Versus Delayed Rehabilitation After Reverse Total Shoulder Arthroplasty for Proximal Humerus Fracture
Proximal humerus fractures can be a debilitating injury in the elderly, impacting the ability to function independently or complete activities of daily living due to pain and restricted shoulder motion.
- Conditions
- Orthopedic Disorder, Humerus Fracture, Shoulder Arthroplasty, Reverse Shoulder Replacement
- Trial name
- NCT06869343
- Testing
- Physical Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Virginia
Osteoporosis, Arthroplasties, Knee Replacement
Abaloparatide Before Total Knee Arthroplasty
The investigator hypothesizes that treating osteoporotic patients with abaloparatide prior to and after total knee arthroplasty will significantly reduce the amount of bone loss.
- Trial name
- NCT04167163
- Testing
- Abaloparatide
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of Wisconsin, Madison
Hip Osteoarthritis, Hip Arthroplasty Replacement
Post-Operative Spinal Block Duration and Pain Relief After Hip Replacement Surgery: Comparing Single-Shot Spinal Ropivacaine and Bupivacaine
This study aims to determine whether isobaric ropivacaine is more suitable than isobaric bupivacaine for spinal anesthesia in outpatient total hip arthroplasty (THA).
- Conditions
- Hip Osteoarthritis, Hip Arthroplasty Replacement, Postoperative Pain After Ambulatory Surgery
- Trial name
- ROBUTHA (NCT07631091)
- Testing
- Spinal Anesthesia with Ropivacaine 15 mg (5 mg/ml), Spinal Anesthesia with Bupivacaine 11 mg (5 mg/ml)
- Volunteers
- 176 people
- Sponsor
- University of Turku
Arthroplasty, Replacement, Knee
Testing Regional Anesthesia Techniques for Up and Early Discharge Following Knee Arthroplasty - A Feasibility Study
To assess feasibility of a a trial investigation postoperative patient-reported quality of recovery after total knee arthroplasty (TKA) with periarticular joint injection (PAI) ± single shot adductor canal block with or without…
- Trial name
- TRUE KnORTH 2 (NCT06054750)
- Testing
- Ropivacaine, Normal saline
- Where
- Canada
- Sponsor
- McMaster University
Osteo Arthritis Knee, Knee Arthritis
Persona IQ Cohort Study
A prospective multicenter longitudinal cohort study of Zimmer Biomet (ZB) Persona IQ The Smart Knee which consists of the Persona Personalized Knee (PPK) System with mymobility® platform that is attempting to develop correlative…
- Conditions
- Osteo Arthritis Knee, Knee Arthritis, Monitoring Orthopedic Devices, Total Knee Arthroplasty
- Trial name
- NCT06089291
- Testing
- Persona IQ
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Zimmer Biomet
Osteoarthritis, Knee, Fractures, Ununited
Modern Methods of Treatment and Diagnosis of Patients With Injuries and Diseases of the Musculoskeletal System
Brief Summary This clinical study investigates the safety and effectiveness of combining advanced regenerative therapies with personalized surgical technology for patients with delayed fracture healing (non-unions), knee…
- Conditions
- Osteoarthritis, Knee, Fractures, Ununited, Arthroplasty, Replacement, Knee
- Trial name
- MTDMS (NCT07628010)
- Testing
- Autologous Mesenchymal Stromal Cells Combined with Platelet-Rich Plasma, Patient-Specific 3D-Printed Surgical Instruments
- Where
- Ukraine
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zaporizhzhiya State Medical University
Arthroplasty, Replacement
Triathlon Tritanium Cone Augments Outcomes Study
The purpose of this study was to evaluate the success rate of the Triathlon Tritanium Cone Augment with the Triathlon TS Total Knee System at 2 years postoperative, defined as absence of revision of the Femoral Cone Augment or…
- Conditions
- Arthroplasty, Replacement, Knee
- Trial name
- NCT02521103
- Testing
- Triathlon Tritanium Cone Augments
- Where
- 9 sites in United States
- Volunteers
- 254 people
- Sponsor
- Stryker Orthopaedics
Knee Arthroplasty, Total, Knee Replacement Arthroplasty
Remote Monitoring After Knee Replacement Surgery
The goal of this clinical trial is to evaluate the effect, cost-effectiveness, safety and satisfaction with replacing standardized, pre-scheduled face-to-face visits with remote monitoring and video consultations or face-to-face…
- Trial name
- OA-AID TKR (NCT07003932)
- Testing
- Remote monitoring, Usual Care
- Where
- Norway
- Volunteers
- 140 people
- Sponsor
- Diakonhjemmet Hospital
Arthroplasty, Replacement, Hip
Low Concentration Local Anesthesia Fascia Iliaca Block for Total Hip Arthroplasty
Fascia iliaca compartment block (FICB) is a documented option for postoperative analgesia for total hip arthroplasty (THA) surgery.
- Trial name
- HALF (NCT06102811)
- Testing
- Low Concentration Local Anesthetic Fascia Iliaca Compartment Block, High Concentration Local Anesthetic Fascia Iliaca Compartment Block
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Toronto
Arthroplasty, Replacement
sACB vs cACB in TKA
This study compares the analgesic efficacy of single-dose adductor canal block (sACB) versus continuous-dose adductor canal block (cACB) for postoperative pain management in total knee replacement patients.
- Conditions
- Arthroplasty, Replacement, Knee
- Trial name
- NCT07581886
- Testing
- Continuous ACB, Single-shot ACB
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Arthroplasty, Replacement, Knee
Evaluation of Triathlon - A New Total Knee Prosthesis System - RSA Triathlon Cruciate Retaining - Cemented vs. Uncemented
The objective is to investigate the Clinical, Radiographic, Roentgen Stereophotogrammetric behaviour and patient outcome when using the Triathlon total knee prosthesis in a prospective randomized clinical trial.
- Trial name
- TriathlonRSA (NCT02525601)
- Testing
- Triathlon CR cemented, Triathlon CR uncemented
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Region Skane