Clinical trials: Arthroplasties, Replacement
Osteoarthritis, Knee, Osteoarthritis, Hip
Liposomal Bupivacaine Versus Standard Analgesia in Total Joint Arthroplasty (TJA)
The purpose of this study is to determine whether liposomal bupivacaine is effective in the management of pain following total joint arthroplasty, as compared to standard of care analgesia.
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Osteoarthritis, Shoulder
- Trial name
- NCT02197273
- Testing
- Liposomal bupivacaine, Standard of care analgesia
- Where
- United States
- Volunteers
- 211 people
- Sponsor
- OhioHealth
Arthroplasty, Replacement
INHANCE Stemless Reverse Shoulder IDE
2:1 Randomized, Controlled, Multi-Center, Prospective, Pre-Market Study of the INHANCE Stemless Reverse Cementless Total Shoulder.
- Conditions
- Arthroplasty, Replacement, Shoulder
- Trial name
- NCT06323980
- Testing
- Reverse Total Shoulder
- Where
- 15 sites in United States
- Volunteers
- 168 people
- Sponsor
- DePuy Orthopaedics
Degenerative Arthritis, Rheumatoid Arthritis
Long Term Follow-up of Integra® Cadence™ Total Ankle System in Primary Ankle Joint Replacement
This study will evaluate the long term performance and safety data for the Cadence™ Total Ankle System (CTAS) when used for primary arthroplasty in patients with primary arthritis (e.g.
- Conditions
- Degenerative Arthritis, Rheumatoid Arthritis, Traumatic Arthritis
- Trial name
- NCT03247023
- Testing
- Implantation of Integra Cadence Total Ankle System
- Where
- 6 sites in Belgium, Canada and 3 more
- Volunteers
- 65 people
- Sponsor
- Smith & Nephew, Inc.
Arthroplasty, Replacement, Knee, Chronic Pain
Effects of Exercise and Education in Patients With Chronic Pain After Total Knee Replacement
The purpose of the study is to investigate whether a 12-week neuromuscular rehabilitation program (NEMEX-TJR) combined with pain neuroscience education (PNE) provides greater pain relief, improvement in physical function and…
- Trial name
- NCT03886259
- Testing
- Neuromuscular exercises (NEMEX-TJR) and pain neuroscience education, Pain neuroscience education
- Where
- 3 sites in Denmark
- Volunteers
- 71 people
- Sponsor
- Aalborg University
Arthroplasty, Replacement, Knee, Patient-controlled Analgesia
Postoperative Patient Controlled Epidural Analgesia After Total Knee Arthroplasty With 2ug/ml Fentanyl Combine With 0.2% Ropivacaine or 0.2% Levobupivcaine
Postoperative epidural analgesia (EA) is an effective and well-accepted modality of pain relief technique after having total knee replacement operation(1,4).
- Trial name
- NCT01158586
- Testing
- Levobupivacaine
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- United Christian Hospital
Surgical, Anxiety
Virtual Reality Therapy to Improve Arthroplasty Outcomes
Virtual reality (VR) has recently emerged as a non-medication-based method to manage anxiety. The patient wears a VR headset and is offered an immersive environment with hypnotic components with sound and imagery in a 3D…
- Conditions
- Surgical, Anxiety, Pain Management, Joint (Knee or Hip Replacement)
- Trial name
- VROOM (NCT07872670)
- Testing
- Virtual Reality Headset, Blood Samples, Questionnaires
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- NHS Highland Research, Development and Innovation Organisation
Pain, Postoperative, Arthroplasty Complications
Intraoperative Ketamine for Patients Undergoing Total Joint Arthroplasty
Prospective randomized double blinded, placebo controlled study that will evaluate the effect of intra-operative ketamine administration on post-operative analgesic requirements and self-reported pain in patients undergoing total…
- Trial name
- NCT04437888
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Degenerative Arthritis, Inflammatory Arthritis
Kinematics of Silastic Joint Replacements in the Hand
To assess in vivo the kinematics of single piece silastic joint replacements in the hand with magnetic resonance imaging
- Trial name
- NCT05441462
- Testing
- Silastic Joint Replacement
- Where
- United Kingdom
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Wrightington, Wigan and Leigh NHS Foundation Trust
Hip Arthroplasty Replacement
Follow up Study of Patients Undergoing Total Hip Arthroplasty CERAFIT® Grafted With Poly Sodium Styrene Sulfonate
The risk of infection after primary Total Hip Arthroplasties (THA)is generally estimated to be less than 1% but remains a severe and costly complication, source of morbidity and even mortality.
- Trial name
- NCT01454271
- Testing
- Total Hip Arthroplasty Replacement
- Where
- France
- Sponsor
- Societe ACTIVBIOMAT
Knee Osteoarthritis
Psoas Sciatic Blockade for Knee Arthroplasty
Objectives: To compare the efficacy of continuous combined psoas sciatic block as a sole anaesthetic technique with conventional combined spinal epidural anesthesia for patients undergoing total knee arthroplasty.
- Trial name
- NCT03088371
- Testing
- Bupivacaine 0.25%, Pajunk Needle, Portex combined spinal epidural kit
- Volunteers
- 80 people
- Sponsor
- Menoufia University
Arthroplasty, Arthroplasty Replacement, Knee
oneKNEE - Prospective, Non-interventional, Multicenter PMCF-Study
Safety and Clinical Performance in terms of clinical outcome of oneKNEE® (total knee arthroplasty TKA), evaluated 2 years after implantation.
- Conditions
- Arthroplasty, Arthroplasty Replacement, Knee, Prosthetic Joint Infections of Knee, TKA Outcomes
- Trial name
- oneKNEE (NCT07682909)
- Testing
- oneKNEE®
- Volunteers
- 1,020 people
- Sponsor
- Aesculap AG
Hip Replacement Arthroplasty
Stimulating Catheter for Lumbar Plexus Block: Better Postoperative Analgesia?
Stimulating catheters have been introduced to reduce the incidence of secondary failure after continuous peripheral nerve blocks, but they effectiveness over traditional nonstimulating catheters is still controversial.
- Trial name
- NCT02162121
- Testing
- Continuous lumbar plexus: stimulating catheter, Spinal Anesthesia, Local anesthetic infusion
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- ASST Gaetano Pini-CTO
Arthroplasties, Replacement, Weight Loss
Weight Loss Before Total Joint Arthroplasty Using A Remote Dietitian and Mobile App
The purpose of this trial is to assess the impact of a 12-week remote dietitian supervised dietary and physical activity weight loss intervention and mobile app for patients with morbid obesity prior to undergoing total joint…
- Conditions
- Arthroplasties, Replacement, Weight Loss, Nutrition
- Trial name
- NCT04330391
- Testing
- Remote dietitian supervised weight loss intervention and mobile app
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Osteoarthritis
Fixed Bearing Versus Mobile Bearing Patient Satisfaction and Clinical Outcome Study
The purpose of this study is to determine if there is a patient satisfaction preference of Fixed Bearing versus Mobile Bearing Unicompartmental Knee Arthroplasty (UKA) in patients who are at a minimum two years post operative.
- Trial name
- NCT02633085
- Testing
- Fixed Bearing or Mobile Bearing UKA
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medacta USA
Postoperative Pain, Total Knee Arthroplasty
US Guided GNB vs Saline Injection for TKA
Do ultrasound-guided genicular nerve blocks with 0.5% bupivacaine provide improved knee analgesia for patients recovering from total knee replacement surgery compared to saline injection? Hypotheses: The investigators hypothesize…
- Conditions
- Postoperative Pain, Total Knee Arthroplasty, Nerve Block
- Trial name
- NCT03316118
- Testing
- bupivacaine, saline
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Northwestern University
Obesity, Knee Osteoarthritis
Wearable Bioimpedance Analyzer for Tracking Body Composition Changes
Obesity, namely at body mass index (BMI) levels exceeding 40kg/m2 (class III obesity), is a risk factor for many diseases including osteoarthritis (OA).
- Trial name
- NCT05986617
- Testing
- InBody Band 2
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Iowa
Ankle Osteoarthritis
Comparison of Customized and Standard Total Ankle Prostheses
The objective of this study is to compare primary total ankle replacement (TAR) performed with a customized procedure (prostheses customized for each patient based on his or her ankle morphology reconstructed from tomographic…
- Trial name
- NCT06193057
- Testing
- Total ankle arthroplasty
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Istituto Ortopedico Rizzoli
Arthroplasty, Knee Replacement
The Effectiveness of Combined Care for Knee Replacement Patients
The goal of this clinical trial is to compare the effectiveness of combined care guidance and general care guidance on pain scores, anxiety levels and joint mobility in patients undergoing total artificial knee replacement.
- Trial name
- NCT06393075
- Testing
- combined care guidance, general care guidance
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Osteoarthritis, Degenerative Joint Disease
Adding Value in Knee Arthroplasty Post-total Knee Replacement (TKR) Care Navigator Trial
The objectives of this research are to: Conduct a proof of concept randomized controlled trial with up to 300 patients undergoing primary total knee replacement (TKA) at Brigham and Women's Hospital (BWH).
- Trial name
- AViKA (NCT01540851)
- Testing
- Care Navigator, Standard Post-Operative TKA Care
- Where
- United States
- Volunteers
- 308 people
- Sponsor
- Brigham and Women's Hospital
Revision Total Knee Arthroplasty
ATTUNE Revision System in the Revision Total Knee Arthroplasty Population
Five-year, Prospective, multi-center, non-randomized, non-controlled study of the ATTUNE® Revision total knee prostheses, utilizing the fixed bearing (FB) and rotating platform (RP) tibial component with the posterior stabilizing…
- Trial name
- NCT03153475
- Testing
- ATTUNE Revision Knee System in Revision Total Knee Arthroplasty
- Where
- 38 sites in United States, Australia and 11 more
- Volunteers
- 400 people
- Sponsor
- DePuy Orthopaedics
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.