Clinical trials: Arthroplasty, Knee Replacement
Hyperglycemia
Postoperative Hyperglycemia After Knee Primary Knee Arthroplasty Surgery
Patients in three hospitals in Sweden who will have knee arthroplasty surgery for the first time are invited to participate in the study, approximately 2000 patients.
- Trial name
- NCT03830931
- Where
- Sweden
- Volunteers
- 1,448 people
- Sponsor
- Lund University
Knee Arthroplasty
Multimodal Modeling of the Knee Joint
The trial will contribute to the development of an innovative algorithm that aims to simplify and improve preoperative knee surgical decision.
- Trial name
- KneeMod (NCT04179812)
- Where
- France
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Total Knee Replacement
Postural Correctors & Activity Trackers in Total Knee Replacement Rehab
To assess the impact of postural corrector on post-operative knee function and activity To evaluate the role of activity tracker in monitoring and enhancing post-operative rehabilitation To assess the effects of postural…
- Trial name
- NCT06877845
- Testing
- Activity Tracker & Postural Corrector, Conventional Therapy
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Acute Postoperative Pain, Chronic Postoperative Pain
Femoral and Epidural Block After Total Knee Arthroplasty
Total knee prosthetic replacement causes severe postoperative pain. Various analgesic techniques have been used in pain control.
- Trial name
- NCT02115945
- Testing
- DN4 test, The SF 12 test, HAD scale
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Knee Disease, Knee Osteoarthritis
Ultrasound Guıded Adductor Canal Block vs Perıcapsular Nerve Group Block in Knee Artroplasty
Knee arthroplasty surgery numbers are increasing depending on joint deformities and cartilage degenerations. Severe postoperative pain may occur in these patients due to surgery and the placed prosthesis.
- Conditions
- Knee Disease, Knee Osteoarthritis, Knee Arthropathy
- Trial name
- NCT06203483
- Testing
- Adductor canal block, PENG block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bursa City Hospital
Arthroplasty, Replacement, Knee
Silkeborg Knee Replacement Cohort Study
In this cohort study, we will investigate short and long term outcomes after knee replacement surgery and identify preoperative and early postoperative factors associated with long term outcome.
- Trial name
- NCT03411083
- Testing
- Total or unicompartmental knee replacement
- Where
- Denmark
- Volunteers
- 1,225 people
- Sponsor
- Central Jutland Regional Hospital
Surgery
Comparison Between Kinesiotaping and Cold Therapy After Total Knee Arthroplasty
The investigators aim was to compare the effectiveness of kinesiotaping and cold therapy on muscle strength and functional performance outcomes in patients with TKA during early postoperative period.
- Trial name
- NCT02747901
- Testing
- KINESIOTAPING, COLD THERAPY
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people
- Sponsor
- Dokuz Eylul University
Knee Osteoarthritis
The Influence of Coronally Knee Alignment on the Tibial Tuberosity Rotation
The primary aim of this study is to find a possible correlation between tibial tuberosity rotation and coronal leg alignment. If correlation exists, a more individual tibial component rotation might be proposed during a total…
- Trial name
- NCT05295602
- Testing
- CT scan
- Where
- Slovenia
- Volunteers
- 200 people
- Sponsor
- Valdoltra Orthopedic Hospital
Osteoarthritis
Anterior Referencing Versus Posterior Referencing in Minimally Invasive Total Knee Arthroplasty
The purpose of this study is to look at two different referencing systems for total knee replacement surgery. In anterior referencing system, referencing cuts are made from the front surface of the femur.
- Trial name
- AR vs PR (NCT01135030)
- Testing
- Total knee
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Heekin Orthopedic Research Institute
Total Knee Replacement, Postoperative Recovery
Efficacy of Kinesiotaping During Rehabilitation Following Total Knee Replacement Surgery
The aim of this study was to examine the efficacy of Kinesiotaping (KT) within postoperative rehabilitation after Total Knee Replacement (TKR) surgery by determining whether KT enhances early postoperative outcomes, in terms of…
- Conditions
- Total Knee Replacement, Postoperative Recovery, Rehabilitation Outcome
- Trial name
- KT-TKR (NCT06831682)
- Testing
- Kinesiotaping (KT), Standard Rehabilitation
- Where
- Germany
- Volunteers
- 102 people
- Sponsor
- SRH Gesundheitszentrum Bad Herrenalb
Osteo Arthritis Knee
Trial of Unicompartmental Versus Total Knee Arthroplasty
This study is a prospective, randomized trial to compare patient outcomes of unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA) for the treatment of medial compartment osteoarthritis.
- Trial name
- NCT03385759
- Testing
- Unicompartmental knee arthroplasty, Total knee arthroplasty
- Where
- 2 sites in United States
- Volunteers
- 112 people
- Sponsor
- Anderson Orthopaedic Research Institute
Arthroplasty, Replacement, Knee
Evaluation of Triathlon - a New Total Knee Prosthesis System - Triathlon vs. Duracon
The objective is to investigate the Clinical, Radiographic, Roentgen Stereophotogrammetric behaviour and patient outcome when using the Triathlon total knee prosthesis in a prospective randomized clinical trial.
- Trial name
- NCT00436982
- Testing
- Cemented Triathlon total knee system, Duracon total knee system
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Stryker Orthopaedics
Primary Gonarthrosis, Genu Recurvatum
The Results of Oxford Unicompartmental Knee Arthroplasty in Patients With and Without Preoperative Genu Recurvatum
The purpose of this study is to explore the effects of the Oxford unicompartmental knee arthroplasty on two groups of patients, namely one with genu recurvatum before the procedure and one without.
- Trial name
- NCT02854189
- Testing
- Oxford unicompartmental knee arthroplasty
- Volunteers
- 104 people
- Sponsor
- Thammasat University
Osteoarthritis
Randomized Controlled Trial of Tranexamic Acid in Total Knee Arthroplasty: Intravenous vs. Topical
The purpose of this study is to determine whether topical or intravenous administration of tranexamic acid during unilateral total knee replacement is more effective at reducing bleeding in the first 24 hours following surgery.
- Trial name
- NCT01940523
- Testing
- Topical Tranexamic Acid, Intravenous Tranexamic Acid
- Where
- 2 sites in United States
- Volunteers
- 640 people
- Sponsor
- Hospital for Special Surgery, New York
Total Knee Arthroplasty, Osteoarthritis
Optimizing Physical Activity Outcomes After Total Knee Arthroplasty
Although total knee arthroplasty is an effective intervention for decreasing knee pain and improving physical function, physical activity levels remain low up to a year after surgery.
- Trial name
- NCT03226106
- Testing
- Physical Activity Behavior Intervention, Attention Control
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- VA Office of Research and Development
Arthroplasty, Hip Replacement, Arthroplasty, Knee Replacement
Early Perioperative Quality Of Recovery After Hip and Knee Arthroplasty: a Retrospective Comparative Cohort Study
Hip and knee replacements are indicated to improve long-term quality of life and pain. These long-term results may depend on the quality of the initial postoperative recovery.
- Trial name
- EARLY-QoR (NCT06107296)
- Where
- France
- Volunteers
- 600 people
- Sponsor
- University Hospital, Strasbourg, France
Osteoarthritis, Knee, Osteoarthritis, Hip
Impact of a POPOP on Preoperative Health, Eligibility, and Clinical & Patient-Reported Outcomes in TJA
In this pilot study, we will test the hypothesis that a POPOP for currently ineligible UAMS orthopedic surgery patients wanting hip or knee replacement improves markers of preoperative health, ability to reach a BMI threshold <40…
- Conditions
- Osteoarthritis, Knee, Osteoarthritis, Hip, Avascular Necrosis, Rheumatoid Arthritis
- Trial name
- NCT04910048
- Testing
- POPOP (preoperative patient optimization program), SOC (standard of care)
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Arkansas
Postoperative Pain
Analgesic Benefit of Preoperative vs. Postoperative Etoricoxib in Total Knee Arthroplasty
Evaluation of the efficacy of preemptive versus postoperative administration of etoricoxib in total knee arthroplasty (TKA).
- Trial name
- NCT02534610
- Testing
- Etoricoxib
- Where
- Romania
- Volunteers
- 165 people
- Sponsor
- Foisor Orthopedics Clinical Hospital
Knee Arthritis, Knee Osteoarthritis
Role of Suzetrigine as a Part of a Multimodal Regimen to Reduce Pain and Opioid Use After Total Knee Arthroplasty
This study is a prospective, single-arm interventional trial enrolling patients undergoing total knee arthroplasty (TKA) for knee arthritis.
- Trial name
- NCT07624526
- Testing
- Suzetrigine
- Where
- 3 sites in United States
- Volunteers
- 75 people
- Sponsor
- Emory University
Knee Pain After Total Knee Arthroplasty, Osteoarthritis Pain
Open-label Milnacipran for Persistent Knee Pain One Year After Total Knee Arthroplasty (TKA)
The current study examines the effects of milnacipran in patients who have chronic persistent knee pain one year or longer after total knee arthroplasty (TKA) to evaluate for a pain-relieving effect.
- Trial name
- NCT01780389
- Testing
- Open-label flexibly dosed milnacipran
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Duke University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.