Clinical trials: Arthroplasty, Replacement, Shoulder
Primary Generalized (Osteo)Arthritis, Post-traumatic Arthrosis of Other Joints, Upper Arm
Simpliciti IDE Trial; Replacing the Humeral Head in Total Shoulder Arthroplasty
The purpose of this study is to demonstrate safety and efficacy of the Simpliciti Shoulder System in total shoulder arthroplasty.
- Trial name
- NCT01390038
- Testing
- Simpliciti™ Shoulder System
- Where
- 14 sites in United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Stryker Trauma and Extremities
Acute Pain
Liposome Bupivacaine Interscalene Total Shoulder
This is a randomized prospective outcomes study comparing two groups of patients. One group will receive liposomal bupivacaine plus bupivacaine and the other will receive bupivacaine alone in interscalene blocks when undergoing…
- Trial name
- NCT03587636
- Testing
- liposome bupivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Closed Fracture Proximal Humerus, Four Part
Reverse Total Shoulder Arthroplasty Versus Open Reduction Internal Fixation of 3&4 Part Proximal Humerus Fractures
Will patients who suffer complex humerus fractures have better functional outcomes and less implant failure with shoulder replacement (reverse total shoulder arthroplasty, RTSA) compared to shoulder repair (open reduction and…
- Trial name
- NCT02597972
- Testing
- Fracture repair, Fracture repair with joint replacement
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Mayo Clinic
Rotator Cuff Tears, Rotator Cuff Tear Arthropathy
Retrovertion Assesment and Study in Elderly Patients With Reverse Total Shoulder Arthroplasty
Determine the optimal degree of retroversion (0-30º) to obtain the best rotational mobility, both internal and external, of the shoulder after implanting a reversed sghoulder arthroplasty (Comprehensive system), and analyze the…
- Trial name
- NCT06316050
- Testing
- humeral retroversion
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Consorci Sanitari de Terrassa
Shoulder Pain, Shoulder Osteoarthritis
Patient Reported Outcome After Stemmed Versus Stemless Total Shoulder Arthroplasty for Glenohumeral Osteoarthritis.
Stemless shoulder arthroplasty systems with uncemented metaphyseal fixation have been used in Europe for glenohumeral osteoarthritis since 2004.
- Conditions
- Shoulder Pain, Shoulder Osteoarthritis, Shoulder Arthritis
- Trial name
- NCT03877315
- Testing
- Stemmed shoulder arthroplasty, Biomet Comprehensive® Total Shoulder System., Stemless shoulder arthroplasty, Biomet Comprehensive® Nano Shoulder System.
- Where
- Denmark
- Volunteers
- 78 people
- Sponsor
- Zealand University Hospital
Cuff Tear Arthropathy, Omarthrosis
EMG and Delta Function in Standard RTSA vs Lateralization
Reverse total shoulder arthroplasty (RTSA) is a well-established method to treat patients with irreparable rotator cuff tears and glenohumeral osteoarthritis.
- Conditions
- Cuff Tear Arthropathy, Omarthrosis, Rotator Cuff Tear Arthropathy
- Trial name
- EMGRTSA (NCT07464977)
- Testing
- Lateralization of glenoid component, Standard implantation technique
- Where
- Austria
- Volunteers
- 130 people
- Sponsor
- Vienna Hospital Association
Post-Operative Pain
Comparison of Pulmonary Function and Efficacy of Different Nerve Block Catheters for Shoulder Surgery
This study is designed to evaluate lung function and pain control of continuous supraclavicular versus suprascapular versus interscalene nerve catheters in subjects undergoing total shoulder replacement.
- Trial name
- NCT02117778
- Testing
- Continuous Nerve Block
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Benaroya Research Institute
Shoulder Osteoarthritis
Subscapularis Strength After Total Shoulder Arthroplasty
This is a randomized, double-blinded, standard of care-controlled clinical trial. The purpose of this study is to determine the difference in subscapularis strength and function after anatomic Total Shoulder Arthroplasty (aTSA)…
- Trial name
- NCT03854357
- Testing
- Subscapularis Rehabilitation, Standard Rehabilitation
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Shoulder Arthroplasty, Shoulder Osteoarthritis
Programmed Intermittent Bolus During Continuous Interscalene Nerve Block for Shoulder Arthroplasty
A new infusion strategy named the 'programmed intermittent bolus' (PIB) technique delivers the hourly dose within minutes compared to the traditional infusion that delivers such dose over an hour.
- Conditions
- Shoulder Arthroplasty, Shoulder Osteoarthritis, Pain Management
- Trial name
- NCT03268837
- Testing
- Programmed Intermittent Bolus, Continuous Infusion
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Osteoarthritis of the Shoulder, Shoulder Pain
Improving Pain Management After Total Shoulder Replacement Using Bupivacaine Liposome
To improve pain control and decrease opioid requirements for subjects undergoing Total Shoulder Replacement.
- Conditions
- Osteoarthritis of the Shoulder, Shoulder Pain, Pain, Postoperative
- Trial name
- NCT04134442
- Testing
- Bupivacaine Liposome Injection, Standard Therapy
- Where
- United States
- Sponsor
- University of Massachusetts, Worcester
Pain
Exparel Interscalene vs Indwelling Catheter
The investigators are comparing an indwelling catheter with intermediate duration local anesthetic to a single shot peripheral nerve block with long acting a local anesthetic (Exparel).
- Trial name
- NCT03827213
- Testing
- Exparel, Indwelling Interscalene Catheter
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Montefiore Medical Center
Arthritis
Evaluation of Implant Fixation in Reverse Total Shoulder Arthroplasty
Reverse total shoulder replacement surgery (RTSA) is performed for individuals with advanced arthritis of the shoulder who also have tears in their rotator cuff muscles.
- Trial name
- NCT02305966
- Testing
- surgery, 0.8 mm diameter Tantalum marker beads
- Volunteers
- 40 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Total Shoulder Arthroplasty, Rotator Cuff Tears
Ultrasound After Total Shoulder Arthroplasty
The purpose of this study would be to evaluate a group of patients status post post-total shoulder arthroplasty to assess the integrity of the rotator cuff using ultrasound.
- Conditions
- Total Shoulder Arthroplasty, Rotator Cuff Tears, Rotator Cuff Injuries
- Trial name
- NCT04416932
- Testing
- Ultasound
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Duke University
Shoulder Joint Disease, Complications; Arthroplasty
Tranexamic Acid in Reverse Total Shoulder Arthroplasty
To the Investigators' knowledge, TXA has not been studied in the setting of reverse total shoulder arthroplasty. We propose a double-blinded, randomized, controlled trial comparing perioperative administration of TXA to placebo…
- Conditions
- Shoulder Joint Disease, Complications; Arthroplasty, Intraoperative Complications, Blood Loss, Surgical
- Trial name
- TXA (NCT02043132)
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Corewell Health East
Primary Anatomic or Reverse Total Shoulder Arthroplasty
Hydrogen Peroxide to the Wound Following Surgical Incision Affecting Cultures in Primary Shoulder Arthroplast
Cutibacterium acnes has been the focus of much recent shoulder literature, as it has been found to be both a common cause of periprosthetic joint infection as well as a common contaminant in shoulder surgery.
- Trial name
- NCT04609306
- Testing
- H2O2 application to incision
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Florida
Shoulder Osteoarthritis, Cuff Tear Arthropathy
Local Infiltration Analgesia Vs. Interscalene Block in Total Shoulder Arthorplasty
Pain management following total shoulder arthroplasty is an important factor in determining patient outcomes and satisfaction. Interscalene brachial plexus blockade has been used successfully to minimize pain in the acute…
- Conditions
- Shoulder Osteoarthritis, Cuff Tear Arthropathy, Massive Rotator Cuff Tear
- Trial name
- NCT04415931
- Testing
- Local infiltration analgesia, Interscalene block
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of Missouri-Columbia
Osteoarthritis
Global® AP™ Total Shoulder Arthroplasty
This study will evaluate the clinical performance of DePuy Global® AP™ Shoulder prosthesis using the anchor pegged glenoid component and clinical and radiographic evaluations.
- Trial name
- NCT00719771
- Testing
- Global® AP™ Total shoulder arthroplasty
- Where
- 4 sites in United States
- Volunteers
- 64 people
- Sponsor
- DePuy Orthopaedics
Primary Reverse Total Shoulder Arthroplasty
Does Undergoing a Prehabilitation Protocol Aimed at Optimizing Scapulothoracic Mobility and Strengthening Improve Internal Rotation After Reverse Shoulder Arthroplasty?
Difficulty with internal rotation (IR) after reverse shoulder arthroplasty (RSA) is common. Current rehabilitation protocols may not optimize IR.
- Trial name
- NCT07145957
- Testing
- Prehabilitation
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Florida
Anatomic Total Shoulder Arthroplasty
Comparison of Glenoid Component Position Using Intelligent Reusable Instrument (IRI) vs Standard Surgical Instruments
The proposed clinical study will enroll patients indicated for standard of care anatomic total shoulder arthroplasty. They will receive all pre operative testing, intra-operative care including all implants and post operative…
- Trial name
- IRI (NCT01801241)
- Testing
- Anatomic TSA using IRI Instrumentation, Anatomic Total Shoulder Arthroplasty
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- The Cleveland Clinic
Shoulder Pain, Shoulder Injuries
MDR - Comprehensive Reverse/Versa Dial Ti Glenosphere
The objective of this retrospective/prospective consecutives series PMCF study is to collect data confirming safety, performance and clinical benefits of the Comprehensive Versa-Dial Reverse Ti Glenosphere when used for primary…
- Conditions
- Shoulder Pain, Shoulder Injuries, Shoulder Fractures, Shoulder Arthritis
- Trial name
- NCT04003272
- Testing
- Comprehensive Reverse Versa-Dial Titanium Glenosphere
- Where
- 2 sites in United States
- Volunteers
- 59 people
- Sponsor
- Zimmer Biomet