Clinical trials: Arthroplasty, Replacement, Shoulder
Shoulder Pain, Opioid Use
Multimodal Analgesia in Shoulder Arthroplasty
Opioid medications are associated with many side effects and the risk of abuse or overdose. Orthopaedic surgeons are currently investigating ways to control pain after surgery while limiting the amount of opioid medications…
- Trial name
- NCT03586934
- Testing
- Acetaminophen, Celecoxib 200mg, Celecoxib 400 mg
- Where
- United States
- Sponsor
- Rush University Medical Center
Osteoarthritis of Shoulder
Evaluation of Structural and Functional Integrity of the Rotator Cuff After Total Shoulder Arthroplasty
The purpose of this study is to examine the rotator cuff muscles in your shoulder at one and two year post total shoulder replacement surgery.
- Trial name
- NCT03921944
- Testing
- CT scan of the shoulders
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Milton S. Hershey Medical Center
Total Shoulder Arthroplasty, Pain Management
ZYNRELEF vs Continuous Catheter for Pain Management Following Shoulder Arthroplasty
The purpose of this study is to determine if local intra-operative application of ZYNRELEF (topical medication) during shoulder replacement surgery improves pain control (as defined by opioid consumption after surgery) compared…
- Trial name
- NCT07280195
- Testing
- Zynrelef, Bupivacaine
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Washington University School of Medicine
Total Shoulder Arthroplasty, Iodine
Iodine Drapes Used in TSA
This study will directly compare the positive culture rate in shoulder arthroplasty using iodine-impregnated versus non-iodine-impregnated drapes used during surgery
- Conditions
- Total Shoulder Arthroplasty, Iodine, Shoulder Surgery
- Trial name
- NCT07721415
- Testing
- Total shoulder arthroplasty, Iodine impregnated drapes, Tissue Culture Samples
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- tnicholson
Shoulder Pain
Liposomal Bupivacaine (Exparel ® ) Plus 0.5% Bupivacaine HCL Versus 0.5% Bupivacaine HCL for Interscalene Nerve Block (ISB) for Patients Undergoing Total Shoulder Arthroplasty(TSA)
This is a phase IV , randomized, single-blind, single-center study comparing patient related outcomes such as postoperative pain and opioid usage for patients who receive ISB 's containing liposomal bupivacaine (Exparel®) plus…
- Trial name
- NCT03913091
- Testing
- Liposomal Bupivacaine, 0.5% Bupivacaine HCL
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Reverse Shoulder Replacement
Tornier Blueprint Planning Software in Patients Receiving Reverse Shoulder Arthroplasty
Compare sizing determined in pre-operative planning of reverse shoulder arthroplasty to operative implant size selected.
- Trial name
- NCT04474665
- Testing
- Reverse shoulder arthroplasty utilizing Blueprint Software
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Spine Institute of Louisiana Foundation
Arthropathy of Shoulder Region, Grossly Deficient Rotator Cuff
Post-Market Study of Comprehensive Reverse Augmented Glenoid and Mini Humeral Tray in Total Shoulder Arthroplasty
This study is a multicenter, prospective, non-randomized, non-controlled, dual cohort post market surveillance study. The primary objective of this study is to confirm the safety and performance of the Comprehensive Reverse…
- Conditions
- Arthropathy of Shoulder Region, Grossly Deficient Rotator Cuff, Osteoarthritis of the Shoulder, Rheumatoid Arthritis Without Humeral Metaphyseal Defects
- Trial name
- NCT03726554
- Testing
- Comprehensive Reverse Porous Augmented Glenoid, Comprehensive Mini Humeral Tray
- Where
- 6 sites in United States
- Volunteers
- 99 people
- Sponsor
- Zimmer Biomet
Shoulder Osteoarthritis
Rehabilitation Following Reverse Total Shoulder Arthroplasty
Reverse total shoulder arthroplasty (RTSA) has been successful in patients with rotator cuff arthropathy, proximal humerus fractures, failed primary total shoulder arthroplasty or failed hemiarthroplasty, and massive irreparable…
- Trial name
- RTSA (NCT03804853)
- Testing
- Rehabilitiation
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- HealthPartners Institute
Shoulder Osteoarthritis
Fixed Inclination Humeral Cut
The purpose of the present study is to determine if a standard humeral cut using a fixed neck shaft angled prosthesis for patients undergoing anatomic TSA is able to restore normal glenohumeral relationships as compared to a…
- Trial name
- NCT03922763
- Testing
- Anatomical cut, Cutting guide
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rothman Institute Orthopaedics
Osteoarthritis, Inflammatory Arthritis
Rotator Cuff Sparing Total Arthroplasty
Design: Prospective, randomized clinical trial, of 120 patients requiring a total shoulder replacement (TSR). Purpose: To collect and evaluate long-term clinical data on patients whose total shoulder replacement (TSR) is…
- Trial name
- NCT01961986
- Testing
- TSR - traditional subscapularis release, TSR - rotator cuff sparing
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- NYU Langone Health
Total Shoulder Arthoplasty
TSA Versus RSA in Patients >75
Total shoulder arthroplasty (TSA) has proven to be a predictable and successful operation for the treatment of symptomatic glenohumeral osteoarthritis (GHOA) with an intact rotator cuff.
- Trial name
- NCT04827277
- Testing
- Reverse Total Shoulder Replacement, Anatomic Total Shoulder Replacement
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Osteoarthritis, Rotator Cuff Tear Arthropathy
Prediction of Development of Scapular Notching Following Reverse Total Shoulder Arthroplasty
The hypothesis is that computer simulated bony impingement of the bone surrounding the spherical glenoid implant (the glenosphere) along the scapular neck on three-dimensional (3-D) computed tomography (CT) imaging analysis is…
- Conditions
- Osteoarthritis, Rotator Cuff Tear Arthropathy, Reverse Total Shoulder Arthroplasty, Scapular Notching
- Trial name
- NCT02052466
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Eric Ricchetti
Surgery, Surgical Site Infection
SURGX Antimicrobial Gel Versus Povidone-iodine Skin Incision Prep in Total Shoulder Arthroplasty
Comparing the growth of intra-operative tissue cultures of Cutibacterium Acnes after primary shoulder replacement when using a no-prep control group versus antimicrobial wound gel versus betadine applied to the skin layer after…
- Conditions
- Surgery, Surgical Site Infection, Cutibacterium Acnes, Prosthetic-joint Infection
- Trial name
- NCT05919888
- Testing
- Povidone-Iodine, SURGX Wound Gel
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- St. Louis University
Glenohumeral Arthritis, Total Shoulder Arthroplasty
Pain Management After Total Shoulder Arthroplasty
The purpose of the study is to determine if pain management after total shoulder arthroplasty is more efficacious with ultrasound guided, continuous Interscalene block or with local tissue infiltration with liposomal bupivacaine.
- Trial name
- NCT03219983
- Testing
- Ropivacaine, liposomal bupivacaine
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- The Christ Hospital
Arthroplasty, Replacement, Shoulder, Shoulder Osteoarthritis
Does BIO-RSA Provides Superior Clinical Outcome Compared to Conventional RSA?
The goal of this clinical trial is to compare two different types of reverse shoulder replacements. Researchers will compare a conventional reverse shoulder replacement with a lateralized reverse shoulder replacement to see if…
- Trial name
- CARS-1 (NCT06025331)
- Testing
- BIO-RSA, RSA
- Where
- 2 sites in Norway
- Volunteers
- 130 people
- Sponsor
- Lovisenberg Diakonale Hospital
Shoulder Arthritis
A Study Comparing Shoulder Replacement Techniques For Patients With Shoulder Arthritis And An Intact Rotator Cuff
The purpose of this study is to determine if patients undergoing anatomic total shoulder arthroplasty (aTSA) will have improved patient reported outcome scores at 1 year compared to those undergoing reverse total shoulder…
- Trial name
- SOAR (NCT07584356)
- Testing
- aTSA, rTSA
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Mayo Clinic
Arthroplasty, Replacement, Shoulder
Evaluation of Regeneten Augmentation for Subscapularis Healing After Total Shoulder Arthroplasty (RESTOR)
The purpose of this study is to evaluate whether augmentation of subscapularis repair with the Regeneten implant after anatomic total shoulder arthroplasty (TSA) can improve rates of subscapularis healing and improve clinical…
- Trial name
- NCT04861714
- Testing
- Regeneten, Standard repair
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Ohio State University
Shoulder Fractures, Shoulder Arthritis Osteoarthritis
Zimmer Biomet Shoulder Arthroplasty PMCF Study
This is a multicenter, prospective, non-controlled post market surveillance study. The objectives of this study are to confirm the safety, performance, and clinical benefits of the Zimmer Biomet Shoulder Arthroplasty systems in…
- Conditions
- Shoulder Fractures, Shoulder Arthritis Osteoarthritis, Shoulder Injury, Shoulder Pain
- Trial name
- NCT06920459
- Testing
- Alliance™ Glenoid
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 50 people
- Sponsor
- Zimmer Biomet
Total Shoulder Arthroplasty
Diagnostic Accuracy of Synovial Biopsy for Implant-Related Shoulder Infections
The purpose of this study is to determine the efficacy of retrieving tissue samples via an x-ray guided needle that is inserted into the infected tissue in the shoulder.
- Trial name
- NCT02143245
- Testing
- Synovial Biopsy, Open Tissue Biopsy
- Where
- 4 sites in Canada
- Volunteers
- 118 people
- Sponsor
- Ottawa Hospital Research Institute
Shoulder Arthritis
Study of Personalized Instrument in Total Shoulder Arthroplasty The P.I.T.S.A. Study
Total shoulder arthroplasty is an effective procedure to improve patients function and to relieve shoulder pain in cases of glenohumeral arthritis. The main challenge of this procedure is implanting the glenoid component.
- Trial name
- PITSA (NCT03839758)
- Testing
- TSA standard, RTSA standard, TSA Blueprint
- Where
- Canada
- Volunteers
- 112 people
- Sponsor
- Université de Montréal